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Lynn Chiu
University of Bordeaux/CNRS
  1.  87
    The Birth of the Holobiont: Multi-Species Birthing Through Mutual Scaffolding and Niche Construction.Lynn Chiu & Scott F. Gilbert - 2015 - Biosemiotics 8 (2):191-210.
    Holobionts are multicellular eukaryotes with multiple species of persistent symbionts. They are not individuals in the genetic sense— composed of and regulated by the same genome—but they are anatomical, physiological, developmental, immunological, and evolutionary units, evolved from a shared relationship between different species. We argue that many of the interactions between human and microbiota symbionts and the reproductive process of a new holobiont are best understood as instances of reciprocal scaffolding of developmental processes and mutual construction of developmental, ecological, and (...)
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  2.  50
    Microorganisms as Scaffolds of Host Individuality: An Eco-Immunity Account of the Holobiont.Lynn Chiu & Gérard Eberl - 2016 - Biology and Philosophy 31 (6):819-837.
    There is currently a great debate about whether the holobiont, i.e. a multicellular host and its residential microorganisms, constitutes a biological individual. We propose that resident microorganisms have a general and important role in the individuality of the host organism, not the holobiont. Drawing upon the Equilibrium Model of Immunity, we argue that microorganisms are scaffolds of immune capacities and processes that determine the constituency and persistence of the host organism. A scaffolding perspective accommodates the contingency and heterogeneity of resident (...)
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  3. Decoupling, Commingling, and the Evolutionary Significance of Experiential Niche Construction.Lynn Chiu - forthcoming - In Tobias Uller & Kevin Laland (eds.), Evolutionary Causation: Biological and Philosophical Reflections. pp. 299-322.
  4.  16
    Natural Selection is Not Environmental Selection: Revisiting Lewontin’s Argument From Niche Construction.Lynn Chiu - unknown
    Richard Lewontin is often cited as an inspiration and founder of what is now known as Niche Construction Theory. The first goal of this paper is to argue that they present distinct arguments from niche construction against Adaptationism. While Niche Construction Theory argues that natural selection is not the only adaptive evolutionary force, Lewontin rejects the externalist characterization of natural selection. The key difference lies in the types of phenomena that are allowed to count as “niche construction” and their argumentative (...)
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  5. Protective Microbiota: From Localized to Long-Reaching Co-Immunity.Lynn Chiu, Thomas Bazin, Marie-Elise Truchetet, Thierry Schaeverbeke, Laurence Delhaes & Thomas Pradeu - 2017 - Frontiers Immunology 8:1678.
    Resident microbiota do not just shape host immunity, they can also contribute to host protection against pathogens and infectious diseases. Previous reviews of the protective roles of the microbiota have focused exclusively on colonization resistance localized within a microenvironment. This review shows that the protection against pathogens also involves the mitigation of pathogenic impact without eliminating the pathogens (i.e., “disease tolerance”) and the containment of microorganisms to prevent pathogenic spread. Protective microorganisms can have an impact beyond their niche, interfering with (...)
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  6.  58
    Immune-Mediated Repair: A Matter of Repair.Paôline Laurent, Marie-Elise Truchetet, Valérie Jolivel, Pauline Manicki, Lynn Chiu & Thomas Pradeu - 2017 - Frontiers in Immunology 8:454.
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