Confusions about the place of race in medicine result in part from a failure to recognize the plurality of race concepts. Recognition that the ordinary concept of race is not identical to the racialist concept of race makes it possible to ask whether there might be a legitimate place for the deployment of concepts of race in medical contexts. Two technical race concepts are considered. The concept of social race is the concept of a social group that is taken to (...) be a racialist race. It is apt for use in examining and addressing the medical effects of discrimination. The populationist concept of race represents race as a kind of biological population. It makes it possible to frame the question whether biological race is a factor in disease susceptibility and drug responsiveness. It is apt for use in determining whether biological race is a medically significant category. (shrink)
This book provides an authoritative account of Hegel's social philosophy at a level that presupposes no specialised knowledge of the subject. Hegel's social theory is designed to reconcile the individual with the modern social world. Michael Hardimon explores the concept of reconciliation in detail and discusses Hegel's views on the relationship between individuality and social membership, and on the family, civil society, and the state. The book is an important addition to the string of major studies of Hegel published (...) by Cambridge. It will interest a broad swathe of readers in philosophy, (both students and specialists), and could be used in courses on political and social theory. (shrink)
This article challenges the orthodox view that there is and can be no scientifically valid concept of race applicable to human beings by presenting a candidate scientific concept of biological race. The populationist concept of race specifies that a “race” is a subdivision of Homo sapiens—a group of populations that exhibits a distinctive pattern of genetically transmitted phenotypic characters and that belongs to an endogamous biological lineage initiated by a geographically separated and reproductively isolated founding population. The viability of the (...) PRC is shown by demonstrating its capacity to withstand a wide range of objections. A common theme is that the objections turn on misconceptions of the idea of a scientific concept of race. The final section argues that the PRC will not foster racism. (shrink)
Explication of the concept of socialrace: the concept variously refers to (1) a social group that is taken to be a racialist race, (2) the social position occupied by a particular social group that is a socialrace and (3) the system of social positions that are socialraces. Socialrace is distinguished from other more familiar forms of social construction. The sense in which socialrace counts as a race concept is explained. The advantages of the term ‘socialrace’ are discussed. The desiderata for (...) a conception of socialrace are articulated. The concept socialrace is contrasted with other similar concepts. (shrink)
Most models of corporate social responsibility revolve around the controversy as to whether business is a single dimensional entity of profit maximization or a multi-dimensional entity serving greater societal interests. Furthermore, the models are mostly descriptive in nature and are based on the experiences of western countries. There has been little attempt to develop a model that accounts for corporate social responsibility in diverse environments with differing socio-cultural and market settings. In this paper an attempt has been made to fill (...) this gap by developing a two-dimensional model of corporate social responsibility and empirically testing its validity in the context of two dissimilar cultures – Australia and Bangladesh. The two dimensions are the span of corporate responsibility and the range of outcomes of social commitments of businesses. The test results confirm the validity of the two-dimensional model in the two environments. The Factor analysis revealed two leading dimensions. Cluster analysis pointed to two distinctive clusters of managers in both Australia and Bangladesh, one consisting of managers with a broad contemporary concept of social responsibility, and the other with a limited narrow view. The paper concludes that corporate social responsibility is two-dimensional and universal in nature and that differing cultural and market settings in which managers operate may have little impact on the ethical perceptions of corporate managers. (shrink)
While new generations of implantable brain computer interface devices are being developed, evidence in the literature about their impact on the patient experience is lagging. In this article, we address this knowledge gap by analysing data from the first-in-human clinical trial to study patients with implanted BCI advisory devices. We explored perceptions of self-change across six patients who volunteered to be implanted with artificially intelligent BCI devices. We used qualitative methodological tools grounded in phenomenology to conduct in-depth, semi-structured interviews. Results (...) show that, on the one hand, BCIs can positively increase a sense of the self and control; on the other hand, they can induce radical distress, feelings of loss of control, and a rupture of patient identity. We conclude by offering suggestions for the proactive creation of preparedness protocols specific to intelligent—predictive and advisory—BCI technologies essential to prevent potential iatrogenic harms. (shrink)
The rule that one must obtain informed consent is well established in medical ethics and an intrinsic part of clinical practice and of research in biomedicine. However, there is a tendency that the rule today is being applied too rigidly and with too little sensitivity to the values that are at stake in connection with different kinds of research protocols. It is here argued that the quality of consent needs to be balanced against variables such as degree of confidentiality and (...) importance of values at stake, in order to be ethically acceptable. Appropriate information and consent procedures should be adjusted accordingly. Three levels are suggested, ranging from extensively informed consent with both written and oral information, through informed refusal with only a limited amount of information given to, at the other end of the scale, just making relevant information available. (shrink)
One might poetically muse that computers have the essence both of logic and machines. Through the case of the history of Separation Logic, we explore how this assertion is more than idle poetry. Separation Logic works because it merges the software engineer’s conceptual model of a program’s manipulation of computer memory with the logical model that interprets what sentences in the logic are true, and because it has a proof theory which aids in the crucial problem of scaling the reasoning (...) task. Scalability is a central problem, and some would even say the central problem, in appli- cations of logic in computer science. Separation Logic is an interesting case because of its widespread success in verification tools. For these two senses of model—the engineering/conceptual and the logical—to merge in a genuine sense, each must maintain their norms of use from their home disciplines. When this occurs, both the logic and engineering benefit greatly. Seeking this intersection of two different senses of model provides a strategy for how computer scientists and logicians may be successful. Furthermore, the history of Separation Logic for analysing programs provides a novel case for philosophers of science of how software engineers and computer scientists develop models and the components of such models. We provide three contributions: an exploration of the extent of models merging that is necessary for success in computer science; an introduction to the technical details of Separation Logic, which can be used for reasoning about other exhaustible resources; and an introduction to the problems, process, and results of computer scientists for those outside the field. (shrink)
This collection of papers in epistemic logic is oriented towards applications to game theory and individual decision theory. Most of these papers were presented at the inaugural conference of the LOFT (Logic for the Theory and Games and Decisions) conference series, which took place in 1994 in Marseille. Among the notions dealt with are those of common knowledge and common belief, infinite hierarchies of beliefs and belief spaces, logical omniscience, positive and negative introspection, backward induction and rationalizable equilibria in game (...) theory. (shrink)
Information is the fourth core element of public health legal preparedness and of legal preparedness for public health emergencies specifically. Clearly, the creation, transmittal, and application of information are vital to all public health endeavors. The critical significance of information grows exponentially as the complexity and scale of public threats increase.Only a small body of organized information on public health law existed before the 21st century: a series of landmark books published beginning in 1926 by Tobey, Grad, and Wing ; (...) model public health laws published as early as 1907; systematic reviews of original research studies published in the 1990s; and a small but growing number of articles published in public health journals and law reviews.With the new century came new public health law programs and activities at the Centers for Disease Control and Prevention, in public health professional associations, and in numerous non-profit and academic organizations. (shrink)
Information is the fourth core element of public health legal preparedness and of legal preparedness for public health emergencies specifically. Clearly, the creation, transmittal, and application of information are vital to all public health endeavors. The critical significance of information grows exponentially as the complexity and scale of public threats increase.Only a small body of organized information on public health law existed before the 21st century: a series of landmark books published beginning in 1926 by Tobey, Grad, and Wing ; (...) model public health laws published as early as 1907; systematic reviews of original research studies published in the 1990s; and a small but growing number of articles published in public health journals and law reviews.With the new century came new public health law programs and activities at the Centers for Disease Control and Prevention, in public health professional associations, and in numerous non-profit and academic organizations. (shrink)
In their environment, plants are continuously submitted to natural stimuli such as wind, rain, temperature changes, wounding, etc. These signals induce a cascade of events which lead to metabolic and morphogenetic responses.In this paper the different steps are described and discussed starting from the reception of the signal by a plant organ to the final morphogenetic response. In our laboratory two plants are studied: Bryonia dioica for which rubbing the internode results in reduced elongation and enhanced radial expansion and Bidens (...) pilosa for which the response occurs at distance, hence pricking the cotyledon of a plantlet induces the growth inhibition of both the hypocotyl and the axillary bud of the pricked cotyledon. (shrink)
This essay presents four ways of thinking about race. They consist of four related but distinct race concepts: the racialist concept of race, which is the traditional, pernicious, essentialist, and hierarchical concept of race; the concept of socialrace, which is the antiracist concept of race as a social construction; the minimalist concept of race, which is the deflationary concept of biological race that represents race as a matter of color, shape and geographical ancestry; and the populationist concept of race, the (...) race concept that represents races as populations, deriving from geographically separated and reproductive isolated founding populations. Taken together, the four concepts can help us better navigate our way through the murky conceptual domain of “race.”. (shrink)
Objective: Ethical guidelines are designed to ensure benefits, protection and respect of participants in clinical research. Clinical trials must now be registered on open-access databases and provide details on ethical considerations. This systematic survey aimed to determine the extent to which recently registered clinical trials report the use of standard of care and post-trial obligations in trial registries, and whether trial characteristics vary according to setting. Methods: We selected global randomized trials registered on http://www.clinicaltrials.gov and http://www.controlled-trials.com. We searched for intervention (...) trials of HIV/AIDS, malaria, and tuberculosis from 9 October 2004, the date of the most recent version of the Helsinki Declaration, to 10 April 2007. Results: We collected data from 312 trials. Fifty-eight percent (58%, 95% CI = 53 to 64) of trial protocols report informed consent. Fifty-eight percent (58%, 95% CI = 53 to 64) of trials report active controls. Almost no trials (1%, 95% CI = 0.5 to 3) mention post-trial provisions. Most trials measure surrogate outcomes. Twenty percent (20%, 95% CI = 16 to 25) of trials measure patient-important outcomes, such as death; and the odds that these outcomes are in a low income country are five times greater than for a developed country (odds ratio (OR) 5.03, 95% CI = 2.70 to 9.35, p = < 0.001). Pharmaceutical companies are involved in 28% (CI = 23 to 33) of trials and measure surrogate outcomes more often than nonpharmaceutical companies (OR 2.45, 95% CI = 1.18 to 5.09, p = 0.31). Conclusion: We found a large discrepancy in the quality of reporting and approaches used in trials in developing settings compared to wealthier settings. (shrink)
Genomic research results and incidental findings with health implications for a research participant are of potential interest not only to the participant, but also to the participant's family. Yet investigators lack guidance on return of results to relatives, including after the participant's death. In this paper, a national working group offers consensus analysis and recommendations, including an ethical framework to guide investigators in managing this challenging issue, before and after the participant's death.
Three experiments investigated the relationship between subjective experience and attentional lapses during sustained attention. These experiments employed two measures of subjective experience to examine how differences in awareness correspond to variations in both task performance and psycho-physiological measures . This series of experiments examine these phenomena during the Sustained Attention to Response Task . The results suggest we can dissociate between two components of subjective experience during sustained attention: task unrelated thought which corresponds to an absent minded disengagement from the (...) task and a pre-occupation with one's task performance that seems to be best conceptualised as a strategic attempt to deploy attentional resources in response to a perception of environmental demands which exceed ones ability to perform the task. The implications of these findings for our understanding of how awareness is maintained on task relevant material during periods of sustained attention are discussed. (shrink)
We surveyed IRB chairs' perspectives on offering individual genetic research results to participants and families, including family members of deceased participants, and the IRB's role in addressing these issues. Given a particular hypothetical scenario, respondents favored offering results to participants but not family members, giving choices at the time of initial consent, and honoring elicited choices. They felt IRBs should have authority regarding the process issues, but a more limited role in medical and scientific issues.
Background The ideal basis of age estimation is considered to be a combination of clinical, skeletal and dental examinations. It is not easy to determine how forensic physicians take account of evidence-based data obtained from medical journals in their medical decision-making. The question of what is an ethically acceptable probability that adolescents are incorrectly considered to be over 18 has not been answered. Methods In a retrospective study over 1 year (2007), 498 files (for 141 female subjects and 357 male (...) subjects) regarding age assessment requested by the public prosecutor's office for purposes of criminal or asylum proceedings were reviewed. Chronological age was estimated from a combination of physical examination, radiographic examination of the left hand and determination of dental status. Results Estimates of chronological age in 498 subjects claiming to be 9–14 years old were incompatible with the alleged age in 356 (71%) when made by the forensic physician but in only 17 (3%) when based on data from published studies on age estimation in adolescents. Conclusions The present study suggests that in most cases the forensic physician ignores the adolescent's word. Medical mission and ethics imply a need to listen to the claims of persons in custody, whatever the risk of false claims. This situation should prompt forensic physicians to keep up with published data on estimating the age of adolescents. (shrink)
The following text is taken from the publisher's website: "Romanticism is, and always has been, one of the most hotly contested terms in literary and cultural history. Many of the writers now described as Romantic refused to be defined by the word: 'it would be such bad taste', said Byron in 1820. Lovejoy spoke of a plurality of ‘romanticisms’, born of distinct thought complexes, whilst René Wellek argued that literatures labelled Romantic indicated common conceptions. Comparably, in the post-World War II (...) period, political commentators have seen Romanticism as either profoundly radical or deeply reactionary. This significant collection gathers key critical discussions that explore the complex and many-sided nature of the 'Romantic'. A new introduction by the editors, a full index and chronological table of contents guide the reader through the wealth of material dedicated to a term that is both extremely unstable and remarkably persistent.". (shrink)
Two-classes of phase-space spin quasi-distribution functions are introduced and discussed. The first class of these distributions is based on the delta function construction. It is shown that such a construction can be carried out for an arbitrary spin s and an arbitrary ordering of the spin operators. The second class of the spin distributions is constructed with the help of the spin coherent states. The connection of the spin coherent states to the Stratonovich formalism is established and discussed. It is (...) shown that the c-number phase-space description of quantum fluctuations provides a simple statistical picture of quantum fluctuations of spinoperators in terms of random directions on a unit sphere. For quantum states of the spin system the statistics of these random orientations is given by non-positive spin quasi-distribution functions. It is shown that the application of these spin quasi-distribution functions to the Einstein-Podolsky-Rosen correlations provide an insight into the quantum theory of measurement. (shrink)