By utilizing new information from both clinical and experimental (lesion, electrophysiological, and gene-activation) studies with animals, the anatomy underlying anterograde amnesia has been reformulated. The distinction between temporal lobe and diencephalic amnesia is of limited value in that a common feature of anterograde amnesia is damage to part of an comprising the hippocampus, the fornix, the mamillary bodies, and the anterior thalamic nuclei. This view, which can be traced back to Delay and Brion (1969), differs from other recent models in (...) placing critical importance on the efferents from the hippocampus via the fornix to the diencephalon. These are necessary for the encoding and, hence, the effective subsequent recall of episodic memory. An additional feature of this hippocampalanterior thalamic and the perirhinal–medial dorsal thalamic systems are compromised, leading to severe deficits in both recall and recognition. (shrink)

As with the dialogue, so with the slave-boy episode within it, two questions are handled, one of them substantive, the other a question of method. The substantive question is how to double the square of a side of 2 units; the procedural question is how, if at all, can an answer be found by one who does not know it. It develops that the answer must be sought exclusively among opinions which the boy already holds, by means of questioning. What (...) I want to argue is that the boy's lesson is not an unqualified success any more than is Meno's. I shall maintain that, exactly parallel to the main discussion, Plato means to cast suspicion on the substantive answer which Socrates and the boy arrive at, and for an exactly parallel reason: the inquiry has been conducted improperly. On the other hand the lesson is far from an unqualified failure, since despite its lack of substantive result, it contains an important message about method. Just as it becomes clear in the discussion with Meno that any disciplined inquiry into virtue must refrain from asking what virtue is like until it has settled the more fundamental question of what virtue itself is, so in the slave-boy passage it is learned that we must refrain from asking what the solution to our problem is like until we have settled on what the solution itself is. (shrink)

The goal of our target article was to review a number of emerging facts about the effects of limbic damage on memory in humans and animals, and about divisions within recognition memory in humans. We then argued that this information can be synthesized to produce a new view of the substrates of episodic memory. The key pathway in this system is from the hippocampus to the anterior thalamic nuclei. There seems to be a general agreement that the importance of this (...) pathway has previously been underestimated and that it warrants further study. At the same time, a number of key questions remain. These concern the relationship of this system to another temporal-lobe/diencephalic system that contributes to recognition, and the relationship of these systems to prefrontal cortex activity. (shrink)

Health sector financing reforms that have been ongoing over the last decade in most developed countries are rooted in philosophical terms in the ideology of economic rationalism. The ideology suggests that it is possible to artificially create markets for activities in contexts where markets do not develop naturally, and that the creation of these artificial markets leads to resource allocations that are both more efficient and more equitable than historical arrangements. The application of the ideology to New Zealand's health sector (...) has generated some benefits—for example, a more rational approach to influencing the decisions of self-interested health care providers; but it has also generated some costs—for example, on ideological grounds it has brought into question the non-market rationales for maintaining a national health service system. (shrink)

The book's purpose is to introduce the reader to questions in Christian ethics through a careful examination of the fundamental meta-ethical questions posed by the "state we're in," whether understood as a new phase of modernity or as postmodernity.

Ronald Preston found Alasdair MacIntyre's analysis of plurality and incommensurability unconvincing, holding that, ultimately, a common rationality enabled disparate perspectives to achieve shared positions. This commitment made Preston sceptical of theologies which drew on MacIntyre to deny the possibility of meaningful dialogue with economics but he ignored the argument that shared liberal roots might constrain his own critique of market institutions. Preston's theological conversation with economics assumes a state-based capitalism, political dominance over economics and a thin plurality. Globalisation challenges such (...) foundations severely but MacIntyre's focus on communities of tradition offers only a weak challenge to global economic power. Preston's understanding of the significance of finitude in economics and MacIntyre's focus on the problems of plurality and the communitarian response are both important in any response to contemporary globalisation. This article explores whether the respective virtues of Preston's and MacIntyre's approaches can coalesce in a theology adequate to the global era. (shrink)