This paper lays out some of the empirical evidence for the importance of neural reuse—the reuse of existing (inherited and/or early-developing) neural circuitry for multiple behavioral purposes—in defining the overall functional structure of the brain. We then discuss in some detail one particular instance of such reuse: the involvement of a local neural circuit in finger awareness, number representation, and other diverse functions. Finally, we consider whether and how the notion of a developmental homology can help us understand the relationships (...) between the cognitive functions that develop out of shared neural supports. (shrink)

Genetic engineering is a rapidly evolving field of research with potentially powerful therapeutic applications. The technology CRISPR-Cas9 not only has improved the accuracy and overall feasbility of genome editing but also has increased access to users by lowering cost and increasing usability and speed. The potential benefits of genetic engineering may come with an increased risk of off-target events or carcinogenic growth. Germ-line cell therapy may also pose risks to potential progeny and thus have an additional burden of proof for (...) safety. Persons responsible for evaluating the ethics of genetic-engineering research programs or clinical trials should do so in light of the nature, integrity, and totality of the human person. Recent news of the implantation and birth of genetically engineered human embryos is just one example of increased rogue science. Health care institutions should consider what steps can be taken to prevent or slow this trend. (shrink)

In 1935, a group of mathematical statisticians in the United States announced the founding of a new professional organization, the Institute of Mathematical Statistics. In the coming years, this institution became a significant source of support for the growing community of mathematical statisticians. Thus it would seem that the formation of the Institute marked the beginning of the process of the creation of that community. This paper, however, argues that those who initially participated in the Institute constituted a small, loosely (...) organized, but wellconnected group within the broader scientific world even before they joined together formally to promote their discipline. We will examine some aspects of their education, employment, and interests in order to determine how American mathematical statisticians set themselves apart from other scientists and helped to define their discipline before the community acquired its official status. (shrink)