This document presents the Bonn PRINTEGER Consensus Statement: Working with Research Integrity—Guidance for research performing organisations. The aim of the statement is to complement existing instruments by focusing specifically on institutional responsibilities for strengthening integrity. It takes into account the daily challenges and organisational contexts of most researchers. The statement intends to make research integrity challenges recognisable from the work-floor perspective, providing concrete advice on organisational measures to strengthen integrity. The statement, which was concluded February 7th 2018, provides guidance on (...) the following key issues: § 1. Providing information about research integrity§ 2. Providing education, training and mentoring§ 3. Strengthening a research integrity culture§ 4. Facilitating open dialogue§ 5. Wise incentive management§ 6. Implementing quality assurance procedures§ 7. Improving the work environment and work satisfaction§ 8. Increasing transparency of misconduct cases§ 9. Opening up research§ 10. Implementing safe and effective whistle-blowing channels§ 11. Protecting the alleged perpetrators§ 12. Establishing a research integrity committee and appointing an ombudsperson§ 13. Making explicit the applicable standards for research integrity. (shrink)

This document presents the Bonn PRINTEGER Consensus Statement: Working with Research Integrity—Guidance for research performing organisations. The aim of the statement is to complement existing instruments by focusing specifically on institutional responsibilities for strengthening integrity. It takes into account the daily challenges and organisational contexts of most researchers. The statement intends to make research integrity challenges recognisable from the work-floor perspective, providing concrete advice on organisational measures to strengthen integrity. The statement, which was concluded February 7th 2018, provides guidance on (...) the following key issues: § 1.Providing information about research integrity § 2.Providing education, training and mentoring § 3.Strengthening a research integrity culture § 4.Facilitating open dialogue § 5.Wise incentive management § 6.Implementing quality assurance procedures § 7.Improving the work environment and work satisfaction § 8.Increasing transparency of misconduct cases § 9.Opening up research § 10.Implementing safe and effective whistle-blowing channels § 11.Protecting the alleged perpetrators § 12.Establishing a research integrity committee and appointing an ombudsperson § 13.Making explicit the applicable standards for research integrity. (shrink)

Whereas in the 1970s early bioethicists believed that bioethics is an arena for the application of philosophical theories of utilitarianism, deontology, and natural law thinking, contemporary policy-oriented bioethicists seem rather to be keen on framing ethical issues through political ideologies. Bioethicists today are often labeled “liberal” or “communitarian,” referring to their different understandings of the relationship between the individual and society. Liberal individualism, with its conceptual base of autonomy, dignity, and privacy, enjoyed a long period of dominance in bioethics, but (...) it has increasingly come under attack from ideologies promoting a more salient role for concepts of solidarity, community, and public interest. (shrink)

A decade has passed since the mapping of the human genome—an event that paved the way for many new developments in biomedicine and related fields. In ethics, this milestone was accompanied by calls for changes in ruling ethical frameworks.

As artificial intelligence systems are becoming increasingly autonomous and will soon be able to make decisions on their own about what to do, AI researchers have started to talk about the need to align AI with human values. The AI ‘value alignment problem’ faces two kinds of challenges—a technical and a normative one—which are interrelated. The technical challenge deals with the question of how to encode human values in artificial intelligence. The normative challenge is associated with two questions: “Which values (...) or whose values should artificial intelligence align with?” My concern is that AI developers underestimate the difficulty of answering the normative question. They hope that we can easily identify the purposes we really desire and that they can focus on the design of those objectives. But how are we to decide which objectives or values to induce in AI, given that there is a plurality of values and moral principles and that our everyday life is full of moral disagreements? In my paper I will show that although it is not realistic to reach an agreement on what we, humans, really want as people value different things and seek different ends, it may be possible to agree on what we do not want to happen, considering the possibility that intelligence, equal to our own, or even exceeding it, can be created. I will argue for pluralism which is compatible with objectivism. In spite of the fact that there is no uniquely best solution to every moral problem, it is still possible to identify which answers are wrong. And this is where we should begin the value alignment of AI. (shrink)

This paper is concerned with analyzing transformations in the development, marketing, prescription, and access issues of pharmaceuticals, paying special attention to a variety of ethical and social aspects. A major focus of the article is on pharmacogenetics – a rapidly developing discipline which in the near future might well have a major effect on both drug development and clinical medicine.

What is Estonian Philosophy? What is Estonian Philosophy?

This personal letter describes the history and current situation of philosophy in Estonia. We sketch the development of academic philosophy since the foundation of Tartu University in 1632, and describe the current philosophical landscape. We discuss the challenges we are facing in trying to find a balance between the responsibility that a discipline in the humanties in a small country has with respect to local culture and society on the one hand, and our ambitions to build up an internationally collaborating (...) department with an international graduate programme on the other. We close with a description of the relation between academic philosophy and Estonian society and the role that the Center for Ethics in Tartu plays in supporting that relation. (shrink)

This article focuses on healthcare ethics discussions in Estonia. We begin with an overview of the reform policies that the healthcare institutions have undergone since the region regained independence from the Soviet Union in 1991. The principles of distributing healthcare services and questions regarding just what ethical healthcare should look like have received abundant coverage in the national media. An example of this is the exceptionally public case of V—a woman with leukemia whose expensive drugs the national health insurance fund (...) refused to compensate. In our subsequent discussion, we focus on a grand-scale local healthcare and research project—the Estonian Genome Project—that attempts to include 1 million DNA samples into one database. (shrink)