Enzymatic misrepair of ionizing‐radiation‐induced DNA damage can produce large‐scale rearrangements of the genome, such as translocations and dicentrics. These and other chromosome exchange aberrations can cause major phenotypic alterations, including cell death, mutation and neoplasia. Exchange formation requires that two (or more) genomic loci come together spatially. Consequently, the surprisingly rich aberration spectra uncovered by recently developed techniques, when combined with biophysically based computer modeling, help characterize large‐scale chromatin architecture in the interphase nucleus. Most results are consistent with a picture (...) whereby chromosomes are mainly confined to territories, chromatin motion is limited, and interchromosomal interactions involve mainly territory surfaces. Aberration spectra and modeling also help characterize DNA repair/misrepair mechanisms. Quantitative results for mammalian cells are best described by a breakage‐and‐reunion model, suggesting that the dominant recombinational mechanism during the G0/G1 phase of the cell cycle is non‐homologous end‐joining of radiogenic DNA double strand breaks. In turn, better mechanistic and quantitative understanding of aberration formation gives new insights into health‐related applications. BioEssays 24:714–723, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

The assumption in current U.S. mainstream medicine is that birthing requires hospitalization. In fact, while the American College of Obstetricians and Gynecologists supports the right of every birthing person to make a medically informed decision about their delivery, they do not recommend home birth owing to data indicating greater neonatal morbidity and mortality. In this article, we examine the evidence surrounding home birth in the United States and its current limitations, as well as the ethical considerations around birth setting.

Decentralized biobanking “de-bi” applies blockchain technology and web3 values to embed the procedural principles of transparency, accountability, and inclusion into the biomedical research ecosyst...

Occupy Wall Street, Indignés, Nuit Debout - plus que jamais la question est posée de définir la vie que nous souhaitons choisir et vivre. Une vie vécue est inséparable de ses formes, de ses modalités, de ses régimes, de ses gestes, de ses façons, de ses allures... qui sont déjà des idées. Le monde, tel que nous le partageons et lui donnons sens, ne se découpe pas seulement en individus, en classes ou en groupes, mais aussi en "styles", qui sont (...) autant de phrasés du vivre, animé de formes attirantes ou repoussantes, habitables ou inhabitables, c'est-à-dire de formes qualifiées : des formes qui comptent, investies de valeurs et de raisons d'y tenir, de s'y tenir, et aussi bien de les combattre. C'est sur ce plan des formes de la vie que se formulent aujourd'hui beaucoup de nos attentes, de nos revendications, et surtout de nos jugements. C'est toujours d'elles que l'on débat, et avec elles ce sont des idées complètes du vivre que l'on défend ou que l'on accuse. Une forme de vie ne s'éprouve que sous l'espèce de l'engagement, là où toute existence, personnelle ou collective, risque son idée. Vouloir défendre sa forme de vie, sans tapage, en la vivant, mais aussi savoir en douter et en exiger de tout autres, voilà à quoi l'histoire la plus contemporaine redonne de la gravité. Bien au-delà du champ de l'art, Marielle Macé propose la construction critique d'une véritable stylistique de l'existence. Cela suppose de s'intéresser sans préjugé à tout ce qu'engagent les variations formelles de la vie sur elle-même - styles, manières, façons - et de ne pas traiter forcément de vies éclatantes, triomphantes, d'apparences prisées ou de corps élégants. Ce n'est pas seulement la littérature mais bien toutes les sciences humaines qui, pour comprendre le monde immédiat, sous nos yeux, doivent s'y rendre vraiment attentives. (shrink)

Software vulnerabilities are the root cause for a multitude of security problems in computer systems. Owing to their efficiency and tight control over low-level system resources, the C and C++ programming languages are extensively used for a myriad of purposes, from implementing operating system kernels to user-space applications. However, insufficient or improper memory management frequently leads to invalid memory accesses, eventually resulting in memory corruption vulnerabilities. These vulnerabilities are used as a foothold for elaborated attacks that bypass existing defense methods. (...) In this paper, we summarise the main memory safety violation types (i.e. memory errors), and analyse how they are exploited by attackers and the main mitigation methods proposed in the research community. We further systematise the most relevant techniques with regards to memory corruption identification in current programs. (shrink)

Pasteur, théologien, philosophe cartésien et éditeur d’ouvrages spirituels, Pierre Poiret occupe un statut particulier et original dans l’histoire des idées religieuses : il incarne le rôle du « passeur spirituel », celui dont la mission est de transmettre à la postérité l’héritage des auteurs mystiques. Poiret n’est pas un mystique, mais un spécialiste de la « théologie mystique ». Mais qu’est-ce que le mot mystique désigne pour un protestant français du Refuge résidant en Hollande? Par quels moyens, selon Poiret, la (...) théologie mystique peut sortir de sa niche et s’adresser à un public élargi, toute confession confondue? Et encore, en quelle mesure son activité d’éditeur s’inscrit dans le cadre des querelles sur la mystique qui ont marqué la fin du xviie siècle? Telles sont les questions auxquelles cet article tentera de répondre. (shrink)

Most decision-making research in economics focuses on individual decisions. Yet, we know, from psychological research in particular, that individual preferences can be sensitive to social pressures. In this paper, we study the impact of a group environment on individual preferences for risky and ambiguous prospects. In our experiment, each participant was invited to make a series of lottery-choice decisions in two different conditions. In the Alone condition, individuals made private choices, whereas in the Group condition, individuals belonged to a three-person (...) group and group members’ choices were aggregated according to either a majority or unanimity rule. This design allows us to study the impact of a group environment on individuals’ attitude towards both risky and ambiguous prospects, while controlling for the decision rule used in the group. Our experimental results show that when individuals are in the Group condition, they tend to be less risk averse and more ambiguity averse than when they are not part of a group. Our experiment also suggests that the decision rule matters as it shows that these two trends tend to be stronger when the group implements a unanimity rule. Specifically, we found that individuals who belong to a group implementing a unanimity rule are significantly less risk averse than individuals who belong to a group that relies on the majority rule. We obtained a similar—but non-significant—result under ambiguity. (shrink)

Psychologists, as well as other mental health professionals, face unique demands in the workplace that create increased risk for burnout. This article discusses burnout prevalence and detection, including issues of complexity regarding diagnosis and assessment. An ethical lens is utilized to explore problems that may arise due to burnout, and the ethical responsibility of practicing self-care. Recommendations for graduate clinical training programs as well as practicing professionals are suggested, including strategies for monitoring self and others for warning signs of burnout (...) and implementing self-care. (shrink)

Tirant son titre du prochain manifeste à paraître des deux auteurs, ce bref article met en relief la complicité intellectuelle entre Stefano Harney et Fred Moten au sein de nos sensibilités contemporaines. Il suggère quelques façons de les entendre dialoguer ensemble – entre eux, avec nous, parmi nous.

The ancient Stoics proposed one of the most sophisticated and influential ethical frameworks in the history of philosophy. Its impact on theory and practice lasted for centuries during the Hellenistic and Roman periods. Today, their arguments and theories still inform many contemporary ethical debates. Moreover, some of the framework’s main tenets have been used as a theoretical foundation for cognitive–behavioural therapy (CBT), a widely used psychosocial intervention for improving mental health. Much of its lasting impact is the result of the (...) special attention Stoic ethics pays to moral psychology, action theory and education. Stoics consider one of the main components of the development of virtue to be a careful and systematic training of our desires and aversions. -/- This chapter will offer a clear, succinct and up-to-date discussion of four main topics: (1) the Stoic theory of desire; (2) the complex taxonomies of desire offered by the ancient Stoics; (3) the arguments, educational strategies, and practices the Stoics recommend to discipline our soul and extirpate our irrational desires and finally (4) a brief discussion of the possibility of adapting the Stoic philosophy for the education of desires in the present day. (shrink)

La denominada “crisis ambiental” que advierte sobre los límites materiales del planeta ha dado lugar a una extensa producción teórica durante décadas. Producción que, como regla general, ha relegado la relectura de los textos clásicos de las ciencias sociales. El presente artículo rescata algunos debates contemporáneos relacionados con la lectura en clave ecológica de la obra de Marx. Obra que adquiere especial importancia al momento de comprender las formas que toma la explotación de la naturaleza bajo el sistema capitalista, problemática (...) resignificada en el marco de las discusiones actuales sobre sustentabilidad ambiental. (shrink)

Should nurses have their own ethics to match specific problems met in their daily routines? How do nurses act in a society that is changing from a 'monocultural' to an 'intercultural' structure? What are the ethical consequences of these changes for their many tasks? How can the ethical aspects be taught to nurses? This article describes the current status of nursing ethics in the curriculum taught in schools of higher education for nurses in The Netherlands. Aspects of the debate on (...) nursing ethics are outlined and ideas about its future as a subject and discipline in nurse education are offered. Est-ce que le personnel infirmier doit avoir son éthique à soi pour faire face aux problèmes spécifiques dans la routine journalière? Et comment les infirmiers/ères se comportent-ils dans une société qui est en train de changer de la 'monoculture' en 'interculture'? Quels sont les conséquences éthiques de leur tâches? Comment peuvent ces aspets éthiques être enseignés aux infirmiers/ères? Cet article parle de l'état courant de l'éthique infirmier dans l'enseignement dans les écoles de l'education supérieure pour infirmiers/ères en Hollande. En plus, il donne une esquisse de la discussion sur l'éthique infirmier et donne quelques idées pour le futur de l'éthique infirmier comme sujet et discipline en soi dans l'éducation des infirmiers/ères. Sollte das Pflegepersonal seine eigene Ethik haben um den spezifischen Problemen seiner täglichen Routine gewachsen zu sein? Wie soll das Pflegepersonal in einer Gesellschaft handeln, die im Wechsel ist von einer 'Monokultur' zu einer 'Interkultur'? Was sind die ethischen Konsequenzen ihres handeln? Wie können diese ethischen Aspekte dem Pflegepersonal gelehrt werden? Dieser Artikel beschreibt den gegenwärtigen Zustand der Krankenpflege-Ethik im Lehrplan der Schulen für Höhere Ausbildung für Pflegepersonal in Holland. Er gibt auch einen Umriss über die Debatte über Krankenpflege-Ethik und formuliert einige Ideen für die Zukunft der Krankenpflege- Ethik als ein Thema und eine Disziplin in der Ausbildung des Pflegepersonals. (shrink)

Disparities in maternal morbidity and mortality for Latinx populations are a paradigmatic example of the now widely acknowledged structural racism in U.S. health care that predisposed minorities to...

The book presents insights from a mixed methodology study that examines recent mobility patterns exhibited by the middle classes. Its major contributions are two-fold: theoretically, it advances the conceptualisation of middle class migration; empirically, it analyses the migratory motivations of a relatively new Latin-American group in Australia. The accelerated insertion of the Mexican society into globalisation processes is strongly linked not only to the growing participation in migration phenomena but also to people's outflow to new destinations. Although studies of Mexican (...) emigration are vast, research on Mexican skilled migration is scarce, and research that focuses on mobility to non-USA destinations is even scarcer. Mexicans are a relatively new addition to Australia's multicultural society, and little is known about this group's profile and why they choose to migrate to Australia. Employing a mixed methodology approach, the book provides a comprehensive portrait of migration in a new group. (shrink)

Conscience – a catholic anthropological vision In the catholic tradition conscience always played an important role as visible in the ‘clausula Petri’ (Ac 5,30-33) or in Paul’s belief in its wisdom (Rm 2,14-16). Conscience can break rules (‘epikeia’), but should not stand up against the church as such. Luther’s historical deed left behind a distrust in conscience in the Catholic Church; it took 400 years to restore Paul’s vision of the conscience as the highest authority – if it is formed (...) and reaches the state of maturity. By his conscience, man is called to be as God created him; he is called by others to develop and to respect their dignity. He is also called by the world to form it according to its higher possibilities which cannot be realized but by man. Conscience is God’s voice in the person where his promises can be heard. Though conscience is free, it is the place where responsibility is formed according to what someone can and should do. This is why the conscience will keep its unavoidable and undeniable role – even in a postmodern context. (shrink)

El presente trabajo propone analizar la manera en que Agustín de Hipona recepciona el pensamiento de Tertuliano, autor cristiano latino, también africano, del que lo separan unos 200 años. Las principales menciones al cartaginés tienen lugar en la crítica agustiniana a la concepción de la corporeidad del alma defendida por Tertuliano. A fin de poder analizar los argumentos y los conceptos filosóficos utilizados por el hiponense en el desarrollo de su crítica presentamos, en primer lugar, una breve introducción a Tertuliano (...) (c. 160- c. 220), deteniéndonos en algunos pasajes cruciales de su obra titulada _De anima_ (208/210). En segundo lugar, nos dedicamos a presentar y analizar la discusión que lleva adelante Agustín respecto de la tesis de la corporeidad del alma humana en _De Genesi ad litteram _(finalizado hacia el 415)_,_ y en _De anima et eius origine, _escrita posteriormente, entre 419 y 420. Evaluamos entonces la posición del hiponense respecto de la hipótesis traducionista sobre el alma humana, ciertamente vinculada al corporalismo defendido por Tertuliano. (shrink)

The McGurk illusion occurs when listeners hear an illusory percept, resulting from mismatched pairings of audiovisual speech stimuli. Hearing a third percept—distinct from both the auditory and visual input—has been used as evidence of AV fusion. We examined whether the McGurk illusion is instead driven by visual dominance, whereby the third percept, e.g., “da,” represents a default percept for visemes with an ambiguous place of articulation, like/ga/. Participants watched videos of a talker uttering various consonant vowels with and without audios (...) of/ba/. Individuals transcribed the CV they saw or heard. In the V-only condition, individuals predominantly saw “da”/“ta” when viewing CVs with indiscernible POAs. Likewise, in the AV condition, upon perceiving an illusion, they predominantly heard “da”/“ta” for CVs with indiscernible POAs. The illusion was stronger in individuals who exhibited weak/ba/auditory encoding. In Experiment2, we attempted to replicate these findings using stimuli recorded from a different talker. The V-only results were not replicated, but again individuals predominately heard “da”/“ta”/“tha” as an illusory percept for various AV combinations, and the illusion was stronger in individuals who exhibited weak/ba/auditory encoding. These results demonstrate that when visual CVs with indiscernible POAs are paired with a weakly encoded auditory/ba/, listeners default to hearing “da”/“ta”/“tha”—thus, tempering the AV fusion account, and favoring a default mechanism triggered when both AV stimuli are ambiguous. (shrink)

To help eliminate perinatal HIV transmission, the US Department of Health and Human Services recommends against breastfeeding for women living with HIV, regardless of viral load or combined antiretroviral therapy status. However, cART radically improves HIV prognosis and virtually eliminates perinatal transmission, and breastfeeding's health benefits are well-established. In this setting, pregnancy is increasing among American women with HIV, and a harm reduction approach to those who breastfeed despite extensive counseling is suggested. We assess the evidence and ethical justification for (...) current policy, with attention to pertinent racial and health disparities. We first review perinatal transmission and breastfeeding data relevant to US infants. We compare hypothetical risk of HIV transmission from breastmilk to increased mortality from sudden infant death syndrome, necrotizing enterocolitis and sepsis from avoiding breastfeeding, finding that benefits may outweigh risks if mothers maintain undetectable viral load on cART. We then review maternal health considerations. We conclude that avoidance of breastfeeding by women living with HIV may not maximize health outcomes and discuss our recommendation for revising national guidelines in light of autonomy, harm reduction and health inequities. (shrink)

This paper seeks to find possibilities forreconciliation of the implementation of theprecautionary principle and the promotion ofinternational trade of genetically modified organisms,based on the assumption that a sustainabledevelopment is a right objective to strive for. Itstarts with an explanation of the background and therole of the precautionary principle, and describes inwhat way measures based on the precautionary principlecan easily lead to the creation of trade barriers. Thearticle then examines to what extent the WTO (WorldTrade Organisation) Agreements allow theimplementation of the (...) precautionary principle. Inaddition, structural conflicts between the perceptionof the precautionary principle and the concept oftrade liberalisation will be evoked. The last sectionof the paper analyses to what extent the WTO rulesprovide possibilities to avoid or solve theseconflicts in order to attempt to answer the mainquestion: are the precautionary principle and theinternational trade of genetically modified organismsreconcilable? (shrink)

The fragility of the subject is a recurring issue in the work of Anne Enright, one of Ireland's most remarkable and innovative writers. It is this specific interest, together with her attempt to make women into subjects, that inevitably links her work to Bracha Lichtenberg-Ettinger's theory of the matrixial borderspace, a feminine sphere that coexists with the Lacanian symbolic order and that, even before our entrance into this linguistic system, informs our subjectivity. By turning to a point in time before (...) language—the encounter between “self” and “other” during pregnancy—both Enright and Ettinger test the boundaries of and the gaps within the linguistic system. It is the going before language that ultimately enables both to go beyond some of the most persistent dualisms present within the linguistic system and to create room for an alternative—a feminine—understanding of the ethical relationality between self and other. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Respire, Con-spireMarielle Macé (bio)Translated by Alexis Ann StanleyA rather suffocating atmosphere is becoming our customary environment, ecologically, politically, and socially. It is time to affirm "a universal right to breathe"–what Achille Mbembe called the essential demand for justice that escalated during the age of the Anthropocene and is now crudely reemerging in the current pandemic's attack on the respiratory system.But the right to breathe is not "merely" the right (...) to live, to breathe in unpolluted spaces, or to share clean air; it is also the right to a breathable life, a life worth caring for. It is the right to love life, life with and among one another: the right to fraternize in and through breath, the right to detoxify our relationships and breathe with others. To respire with: to con-spire.Because in order to breathe, one needs air, but one especially needs other living beings, a world and landscapes with which to breathe, in which to breathe, and which can breathe through us. To breathe is not only to maintain one's own breath or nourish one's own organic system as if it lived an unconnected life; it is to acquiesce to the world, to the fact that there is a world—this one, precisely—and to participate in it. A person who breathes, in fact, partakes both in and of the world. Moreover, they make a gift to it, contributing to the way of the world in its entirety by a breath that tightly holds the ties binding each of our bodies to the current state of the living._______The lack of air, the feeling of a stifling age, even the fear of overwhelming suffocation—such is our current "natural" condition, the primary characteristic not only of our virtually toxic living environment, but also of our smothering, asphyxiating political condition wrought with violence and discrimination. Such also is the state of our social condition—the way we (rather poorly) create community—or rather, of our distinct social conditions. For there is a very inequitable distribution of the right to air or to breathe determined by which lives "count" and which do not.The Anthropocene is perhaps the age of a new respiratory 'condition.' Toxic fumes, pestilential odors, extensive carbon consumption, agro-chemical [End Page 177] discharge, microparticles, deforestation and soil asphyxiation, radioactive clouds with phantom trajectories and invisible powers of penetration… the history of industrial modernity is that of "the continuous and large-scale alteration of life's atmospheric conditions" (Zimmer 25). Recently, wildfires affecting America and Europe have been adding their horrifying fumes to century-old pollution. Even clouds ("the clouds up there, the marvelous clouds" of Baudelaire) are being targeted: China recently announced the country's intention to accelerate its cloud seeding program1 (in 2008, over one thousand shells loaded with silver iodide were dispersed in order to clear the skies of Beijing and prevent rain from ruining the opening ceremony of the Olympic games. This technique is also used more and more frequently to generate rainfall and avoid agricultural droughts. This type of 'sky colonization' or climate militarization is a profanation of language as much as of nature: to "sow the clouds" (or "grow meat")—even language tells us something is wrong…)It took a great amount of time and much denial before widespread bodily infection and industrial pollution's public health effects could be recognized. Industrialists may object (at times with doctors), but in the most working-class regions, bodies know: "lungs and our sense of smell protest in their own way against any conclusive evidence which would exonerate factories" (Zimmer 23).The history of pollution is, in fact, also a question of exploitation as well as a social history: that of the unequal distribution of air and the inequitable exposure (depending on one's living milieux) to what is oppressive, stifling—in a word, unbreathable. Unsanitary housing, proximity to mines or factories, and lack of access to healthcare are always factors; respiratory diseases are the most prevalent of occupational illnesses2; and the staggering surge in childhood lead poisoning in the very heart of our capitals—the weakest of bodies have... (shrink)

El presente artículo intenta ofrecer un marco documental para la discusión sobre la estructura cosmológica de Ferecides de Siros. Partiendo de la polémica entre quienes le adjudican un cosmograma quinario y aquellos que lo interpretan septenario, proponemos un recorrido por las antiguas doctrinas cosmológicas quinarias, tanto griegas como orientales, a fin de explorar su recurrencia y variedad. Se constata que la disputa religiosa entre los apologetas del cinco y los del siete existía ya en la antigüedad, pudiendo haber afectado a (...) la lectura que los doxógrafos hicieron entonces de la obra de Ferecides. Se expone la teoría de Nick Allen sobre la existencia de una «ideología pentádica» indoeuropea y se critica su sesgo idealista (pitagórico en la línea de Dumézil). Finalmente, se suscribe la hipótesis del origen «protogeométrico» de muchos de estos mapas ontológicos quinarios y se recapitulan las posibles referencias que manejaba el maestro de Pitágoras cuando ideó su teogonía. (shrink)

Cet article se penche sur la question des préférences de Gérard Genette, et chez Gérard Genette : sur ses objets de prédilection, c’est-à-dire sur ses « choses » préférées (œuvres, musiques, formes d’art, figures, paysages, personnes) ; mais surtout sur la préférence comme catégorie de la perception, du goût et du jugement, forme sensible de la relationnalité ou de la transcendance esthétique, et sur ce que cette affaire de préférences dit d’un certain rapport sensible aux généralités et aux catégories de (...) l’esprit, qui anime son œuvre et la porte vers nous. (shrink)

Prenatal ultrasound use is skyrocketing despite limited evidence of improved outcomes. One factor driving this trend is the widely recognized psychological appeal of real-time fetal imaging. Meanwhile, considering imperfect safety evidence, U.S. professional guidelines dictate that prenatal ultrasound—a screening test—should be governed by expected clinical benefits—an opportunity for intervention. However, when women’s healthcare professionals themselves are pregnant, their access to ultrasound technology permits informal, personal use that may deviate from standard-of-care, e.g., for reassurance. Highlighting a poignant case wherein a pregnant (...) obstetrician’s personal ultrasound use had unforeseen negative consequences, we explore this issue within context of professional ethics and informal medical care. We discuss how women’s health professionals’ self-care may influence and inform prenatal care at large. We advocate curtailing informal prenatal ultrasound use, but also potentially broadening accepted indications for or relaxing proscriptions against ultrasounds for patients. Further research and updated, evidence-based, ethically-sound guidelines are needed. (shrink)

Common hospital and surgical center responses to the Covid‐19 pandemic included curtailing “elective” procedures, which are typically determined based on implications for physical health and survival. However, in the focus solely on physical health and survival, procedures whose main benefits advance components of well‐being beyond health, including self‐determination, personal security, economic stability, equal respect, and creation of meaningful social relationships, have been disproportionately deprioritized. We describe how female reproduction‐related procedures, including abortion, surgical sterilization, reversible contraception devices and in vitro fertilization, (...) have been broadly categorized as “elective,” a designation that fails to capture the value of these procedures or their impact on women's overall well‐being. We argue that corresponding restrictions and delays of these procedures are problematically reflective of underlying structural views that marginalize women's rights and interests and therefore threaten to propagate gender injustice during the pandemic and beyond. Finally, we propose a framework for triaging reproduction‐related procedures during Covid‐19 that is more individualized, accounts for their significance for comprehensive well‐being, and can be used to inform resumption of operations as well as subsequent restriction phases. (shrink)

In the USA, there are missed opportunities to diagnose hepatitis C virus in pregnancy because screening is currently risk-stratified and thus primarily limited to individuals who disclose history of injection drug use or sexually transmitted infection risks. Over the past decade, the opioid epidemic has dramatically increased incidence of HCV and a feasible, well-tolerated cure was introduced. Considering these developments, recent evidence suggests universal HCV screening in pregnancy would be cost-effective and several professional organisations have called for updated national policy. (...) Historically, universal screening has been financially disincentivised on the healthcare system level, particularly since new diagnoses may generate an obligation to provide expensive treatments to a population largely reliant on public health resources. Here, we provide ethical arguments supporting universal HCV screening in pregnancy grounded in obligations to respect for persons, beneficence and justice. First, universal prenatal HCV screening respects pregnant women as persons by promoting their long-term health outside of pregnancy. Additionally, universal screening would optimise health outcomes within current treatment guidelines and may support research on treatment during pregnancy. Finally, universal screening would avoid potential harms of risk-stratifying pregnant women by highly stigmatised substance use and sexual behaviours. (shrink)

Background: Little is known about U.S. healthcare provider views and practices regarding evidence, counseling, and shared decision-making about in-hospital versus out-of-hospital birth settings. Methods: We conducted 19 in-depth, semistructured, qualitative interviews of eight obstetricians, eight midwives, and three pediatricians from across the United States. Interviews explored healthcare providers’ interpretation of the current evidence and their personal and professional experiences with childbirth within the existing medical, ethical, and legal context in the United States. Results: Themes emerged concerning risks and benefits, decision-making, (...) and patient-provider power dynamics. Collectively, the narratives illuminated fundamental ideological tensions between in- and out-of-hospital providers arising from divergent assignment of value to described risks and benefits. The majority of physicians focused on U.S.-specific data demonstrating increased neonatal morbidity and mortality associated with delayed access to hospital-based interventions, thereby justifying hospital birth as the standard of care. By contrast, midwives emphasized data demonstrating fewer interventions and superior maternal and neonatal outcomes in high-income European countries, where out-of-hospital birth is more common for low-risk birthing people. A key gap in counseling was revealed, as no interviewees offered anticipatory counseling regarding birth setting options. Providers directly and indirectly illustrated the propensity for asymmetric power relations between birth providers and pregnant people, especially in hospital settings. Conclusions: The narratives highlight the common goal of optimizing maternal and neonatal outcomes despite tensions arising from divergent prioritization of specific maternal and neonatal risks. Our findings suggest opportunities to foster collaboration and optimize outcomes via mutual respect and improved integration of care. (shrink)

Background: The prevalence of anxiety and depression in young students is associated with biosocial factors and scholastic stress. However, few studies have evaluated emotional-affective symptoms that are related to the immune system and antioxidant parameters in young individuals without diagnoses of affective disorders.Aim: This study aims to assess the relationship between emotional-affective symptoms and glutathione concentrations and CD4 and CD8 lymphocyte counts in college students.Methods: College students completed standardized psychometric instruments, including the Perceived Stress Scale, Hamilton Anxiety Scale, Beck Depression (...) Inventory, Familiar Social and Friends Support Scale, and Rosenberg Scale. Blood samples were biochemically analyzed. Analyses of variance were conducted between four groups according to symptom severity.Results: A considerable prevalence of stress, anxiety, and depression symptoms was observed and negatively correlated with self-esteem and socio-familiar support. Perceived stress was sexually dimorphic. Although biochemical parameters were within reference ranges, glutathione, CD4, and CD8 tended to be lower in participants with anxiety and depression symptoms, which may be of predictive value.Conclusion: The relationship between antioxidant/immune parameters and socio-affective scores is latent in undiagnosed college students who might develop affective disorders. The findings suggest that during the initial development of affective disorders, stress management strategies should be implemented to help college students cope with the academic load and monitor negative changes in their physiological state. (shrink)

Unlike previous studies that examine the direct effect of employees’ perceived corporate social responsibility (CSR) on affective organizational commitment (AOC), this article examines a mediated link through organizational trust and organizational identification. Social exchange and social identity theory provide the foundation for predictions that the primary outcomes of CSR initiatives are organizational trust and organizational identification, which in turn affect AOC. The test of the research model relies on data collected from 378 employees of local and multinational companies in South (...) Asia, as well as structural equation modeling to test the postulated relationships. Both organizational trust and organizational identification fully mediate the CSR–AOC link. However, the identification mechanism is significantly stronger than the trust mechanism in terms of building AOC from CSR. Out of four CSR components, CSR toward employees is the strongest predictor of employees’ trust, identification, and AOC, followed by CSR toward community, whereas CSR toward the environment has no effect. Finally, CSR toward community and employees are more associated with social exchange, whereas CSR toward consumers relates more to the social identity process. (shrink)

This article examines the role of the Spanish Atomic Forum as the representative of the nuclear sector in the public arena during the golden years of the nuclear power industry from the 1960s to 1970s. It focuses on the public image concerns of the Spanish nuclear lobby and the subsequent information campaigns launched during the late 1970s to counteract demonstrations by the growing and heterogeneous anti-nuclear movement. The role of advocacy of nuclear energy by the Atomic Forum was similar to (...) that in other countries, but the situation in Spain had some distinguishing features. Anti-nuclear protest in Spain peaked in 1978 paralleling the debates of a new National Energy Plan in Congress, whose first draft had envisaged a massive nuclearization of the country. We show how the approval of the Plan in July 1979, with a significant reduction in the nuclear energy component, was influenced by the anti-nuclear protest movements in Spain. Despite the efforts of the Spanish Atomic Forum to counter its message, the anti-nuclear movement was strengthened by reactions to the Three Mile Island accident in March 1979. (shrink)

Advocates of interactionism in the ethical criticism of art argue that ethical value impacts aesthetic value. The debate is concerned with “the intrinsic question”: the question of whether ethical flaws/merits in artworks’ manifested attitudes affect their aesthetic value (Gaut 2007: 9). This paper argues that the assumption that artworks have intrinsic ethical value is problematic at least in regards to a significant subset of works: fictional artworks. I argue that, insofar as their ethical value emerges only from attitudes attributable to (...) actual agents, fictional artworks only have extrinsic ethical value. I show that what is at stake for interactionism is whether ethical judgements concerning artists’ attitudes in a context, rather than manifested attitudes, are ever aesthetically relevant. I conclude that, without buying into extreme actual intentionalism, a still controversial theory of interpretation that ties artworks’ meaning to actual artists, interactionism fails to show that ethical flaws/merits are aesthetic flaws/merits. (shrink)