Cancer research is experiencing ‘paradigm instability’, since there are two rival theories of carcinogenesis which confront themselves, namely the somatic mutation theory and the tissue organization field theory. Despite this theoretical uncertainty, a huge quantity of data is available thanks to the improvement of genome sequencing techniques. Some authors think that the development of new statistical tools will be able to overcome the lack of a shared theoretical perspective on cancer by amalgamating as many data as possible. We think instead (...) that a deeper understanding of cancer can be achieved by means of more theoretical work, rather than by merely accumulating more data. To support our thesis, we introduce the analytic view of theory development, which rests on the concept of plausibility, and make clear in what sense plausibility and probability are distinct concepts. Then, the concept of plausibility is used to point out the ineliminable role played by the epistemic subject in the development of statistical tools and in the process of theory assessment. We then move to address a central issue in cancer research, namely the relevance of computational tools developed by bioinformaticists to detect driver mutations in the debate between the two main rival theories of carcinogenesis. Finally, we briefly extend our considerations on the role that plausibility plays in evidence amalgamation from cancer research to the more general issue of the divergences between frequentists and Bayesians in the philosophy of medicine and statistics. We argue that taking into account plausibility-based considerations can lead to clarify some epistemological shortcomings that afflict both these perspectives. (shrink)

The International Conference "Tra rito e mito: il Carnevale nella cultura europea" was held online on the 16th and 17th of November 2020. We present twenty-two contributions coming from various fields of the Humanities and written in Italian, French, and German. This proceedings’ foreword traces back the thread that links these essays one with another, i.e., carnivalesque imagery between ritual and mythological dimensions. Moreover, this introduction provides a key to an interpretation of Carnival as a founding instance, both regenerative and (...) conservative, of the European identity. Recovering this instance today, in the midst of a pandemic, responds to the problem of its partial loss in contemporary society, in the hope to rebuild a “free and familiar contact among people”. (shrink)

In this paper we introduce two issues relevantly related to the cognitive phenomenology debate, which, to our minds, have not been yet properly addressed: the relation between access and phenomenal consciousness in cognition and the relation between conscious thought and inner speech. In the first case, we ask for an explanation of how we have access to thought contents, and in the second case, an explanation of why is inner speech so pervasive in our conscious thinking. We discuss the prospects (...) of explanation for both sides of the debate and argue that cognitive phenomenology defenders are in an overall advantageous position. We also propose an account of inner speech that differs from other influential explanations in some interesting respects. (shrink)

This paper explores the relation of thought and the stream of consciousness in the light of an ontological argument raised against cognitive phenomenology views. I argue that the ontological argument relies on a notion of ‘processive character’ that does not stand up to scrutiny and therefore it is insufficient for the argument to go through. I then analyse two more views on what ‘processive character’ means and argue that the process-part account best captures the intuition behind the argument. Following this (...) view, I reconstruct the ontological argument and argue that it succeeds in establishing that some mental episodes like judging, understanding and occurrent states of thought do not enter into the stream but fails to exclude episodes like entertaining. Contrary to what it might seem, this conclusion fits well with cognitive phenomenology views, given that, as I show, there is a way for non-processive mental episodes to be fundamentally related to processive ones, such that they cannot be excl.. (shrink)

Aristotle ’s claim that we become virtuous by doing virtuous actions raises a familiar problem: How can we perform virtuous actions unless we are already virtuous? I reject deflationary accounts of the answer given in _Nicomachean Ethics_ 2.4 and argue instead that proper habituation involves doing virtuous actions with the right motive, i.e. for the sake of the noble, even though learners do not yet have virtuous dispositions. My interpretation confers continuity to habituation and explains in a non-mysterious way how (...) we become virtuous by doing virtuous actions in the right way. (shrink)

Some presuppositions are easier to cancel than others in embedded contexts. This contrast has been used as evidence for distinguishing two fundamentally different kinds of presuppositions, ‘soft’ and ‘hard’. ‘Soft’ presuppositions are usually assumed to arise in a pragmatic way, while ‘hard’ presuppositions are thought to be genuine semantic presuppositions. This paper argues against such a distinction and proposes to derive the difference in cancellation from inherent differences in how presupposition triggers interact with the context: their focus sensitivity, anaphoricity, and (...) question–answer congruence properties. The paper also aims to derive the presuppositions of additive particles such as too, also, again, and of it-clefts. (shrink)

This article presents two ways of contributing to the debate on cognitive phenomenology. First, it is argued that cognitive attitudes have a specific phenomenal character or attitudinal cognitive phenomenology and, second, an element in cognitive experiences is described, i.e., the horizon of possibilities, which arguably gives us more evidence for cognitive phenomenology views.

In what ways and how far does virtue shield someone against suffering evils? In other words, how do non-moral evils affect the lives of virtuous people and to what extent can someone endure evils while staying happy? The central purpose of this chapter is to answer these questions by exploring what Aristotle has to say about the effects of evils in human well-being in general and his treatment of extreme misfortunes.

Advance directives have been hailed for two decades as the best way to safeguard patients’ autonomy when they are totally or partially incompetent. In many national contexts they are written into law and they are mostly associated with end-of-life decisions. Although advocates and critics of ADs exchange relevant empirical and theoretical arguments, the debate is inconclusive. We argue that this is so for good reasons: the ADs’ project is fraught with tensions, and this is the reason why they are both (...) important and deeply problematic. We outline six such tensions, and conclude with some positive suggestions about how to better promote patients’ autonomy in end-of-life decision. We argue that ADs should continue to be an option but they cannot be the panacea that they are expected to be. (shrink)

introduction Dialectic and the notion of tradition The past does not pull back but presses forward. (Hannah Arendt 1977: 10) Through the confrontation over ...

The central idea behind this paper is that presuppositions of soft triggers arise from the way our attention structures the informational content of a sentence. Some aspects of the information conveyed are such that we pay attention to them by default, even in the absence of contextual information. On the other hand, contextual cues or conversational goals can divert attention to types of information that we would not pay attention to by default. Either way, whatever we do not pay attention (...) to, be it by default, or in context, is what ends up presupposed by soft triggers. This paper attempts to predict what information in the sentence is likely to end up being the main point (i.e. what we pay attention to) and what information is independent from this, and therefore likely presupposed. It is proposed that this can be calculated by making reference to event times. The notion of aboutness used to calculate independence is based on that of Demolombe and Fariñas del Cerro (In: Holdobler S (ed) Intellectics and computational logic: papers in honor of Wolfgang Bibel, 2000). (shrink)

There is currently a consensus among comparative psychologists that nonhuman animals are capable of some forms of mindreading. Several philosophers and psychologists have criticized this consensus, however, arguing that there is a “logical problem” with the experimental approach used to test for mindreading in nonhuman animals. I argue that the logical problem is no more than a version of the general skeptical problem known as the theoretician’s dilemma. As such, it is not a problem that comparative psychologists must solve before (...) providing evidence for mindreading. (shrink)

This introduction presents a state of the art of philosophical research on cognitive phenomenology and its relation to the nature of conscious thinking more generally. We firstly introduce the question of cognitive phenomenology, the motivation for the debate, and situate the discussion within the fields of philosophy, cognitive psychology and consciousness studies. Secondly, we review the main research on the question, which we argue has so far situated the cognitive phenomenology debate around the following topics and arguments: phenomenal contrast, epistemic (...) arguments and challenges, introspection, ontology and temporal character, intentionality, inner speech, agency, holistic perspective, categorical perception, value, and phenomenological description. Thirdly, we suggest future developments by pointing to four questions that can be explored in relation to the cognitive phenomenology discussion: the self and self-awareness, attention, emotions and general the... (shrink)

The non-adaptationist approach to evolutionary epistemology was born at the end of the 1970s as an alternative to traditional adaptationist EE. Despite the fact that non-adaptationist EE offers compelling interpretative models and its explanatory power is widely recognised, an organic overview of the broad non-adaptationist field is still lacking. In this paper, I propose to fill this gap. To this effect, after providing a systematisation of the perspectives that are commonly associated with non-adaptationist EE, I will discuss two recurring orders (...) of arguments that non-adaptationist scholars, often independently of one another, put forward against their adaptationist rivals. By offering a way to conceive non-adaptationist evolutionary epistemological approaches as part of a structured whole, the resulting systematic account is meant to provide a reading grid, a compass for orienting oneself in the uneven territories of non-adaptationist EE. Moreover, the consequent identification of two recurring argumentative bodies is intended to add to the explanatory power of non-adaptationist EE, which in finding new strength in numbers eventually acquires a greater critical efficacy against its adaptationist counterpart. (shrink)

Should CSR be approached only on a voluntary basis or should it be complemented with a compulsory regulatory framework? What type of government intervention is more effective in fostering CSR among companies? This paper is an attempt to answer these questions, reviewing the debate between proponents of the voluntary case and the obligatory case for CSR, and critically analysing current international government-led initiatives to foster CSR among companies, and national government-led initiatives in the EU area. Finally, the paper focuses on (...) the Spanish case, as an example of the failure of an exclusively voluntary approach. Despite the rapid uprise of CSR, Spain is still far behind late in CSR promotion strategies. Most action has been undertaken by companies themselves with no common guidelines, governmental support, or independent verification. The lack of a regulatory framework for CSR or ethical investment issues and the virtual absence of other indirect incentives, explains the misbalance between private, public and Third Sector initiatives. Based on the Spanish context which is quite similar to other non-OECD countries, the authors call for a more proactive government position in CSR related issues. The conclusions of the paper detail the features of this regulatory framework and other policies to promote CSR in Spain as well as in other OECD countries. (shrink)

A complete, illustrated survey of Etienne-Jules Marey's work that investigates the far reaching effects of her inventions on stream-of-consciousness literature, psychoanalysis, Bergsonian philosophy, and the art of cubists and futurists.

In this paper I show that a novel ontic reading of explanation, intending to capture the de re essential features of individuals, can support the qualitative view of individual essences. It is argued further that the putative harmful consequences of the Leibniz Principle and its converse for the qualitative view can be avoided, provided that individual essences are not construed in the style of the naïve bundle theory with set-theoretical identity- conditions. Adopting either the more sophisticated two-tier BT or, alternatively, (...) the neo-Aristotelian position of taking essences as natures in the Aristotelian sense, can help to evade these main charges against the qualitative view. The functional parallels with the alternative haecceitistic view of individuation and individual essence will also be considered. (shrink)

Proof-theoretic methods are developed for subsystems of Johansson’s logic obtained by extending the positive fragment of intuitionistic logic with weak negations. These methods are exploited to establish properties of the logical systems. In particular, cut-free complete sequent calculi are introduced and used to provide a proof of the fact that the systems satisfy the Craig interpolation property. Alternative versions of the calculi are later obtained by means of an appropriate loop-checking history mechanism. Termination of the new calculi is proved, and (...) used to conclude that the considered logical systems are PSPACE-complete. (shrink)

We have tested brittleness prediction by integrating well and 3D seismic data using machine learning for Lower Paleozoic shales from the Baltic Basin in northern Poland. The workflow allowed for differentiation of the brittle and ductile zones of the thin shale layers, as well as mapping of the marly formation with superior resolution as compared with the resolution of the original input seismic data. The important part of the success was the appropriate definition of the mineralogical brittleness index tailored to (...) the local geologic conditions. The obtained BI volume outlines the more and less brittle zones in the lower shale unit, i.e., the Sasino Formation, as well as the overlaying unit with high values of BI. The mechanical BI based on the Young’s modulus and Poisson’s ratio did not deliver the desired brittleness characterization of the formations of interest, which confirms the weakness of estimating BI using the above geomechanical measurements alone. The weak point of the reported analysis is the small number of available wells, which makes the prediction’s statistics unsatisfactory. (shrink)

Remembering and forgetting are the two poles of the memory system. Consequently, any approach to memory should be able to explain both remembering and forgetting in order to gain a comprehensive and insightful understanding of the memory system. Can an enactive approach to memory processes do so? In this article I propose a possible way to provide a positive answer to this question. In line with some current enactive approaches to memory, I suggest that forgetting –similarly to remembering– might be (...) constituted within an embodied and active process. Within this process, some simulation and re-enactment paths would acquire more relevance than others. This acquired relevance would make the activation of other paths of recall less likely, thus preventing the memory system from engaging in some episodic simulations. These changes in the likelihood of activation of some paths of recall –the forgotten ones– can be accounted for in an enactive fashion by studying both “internal” and “external” re-enactment and simulation paths. With regard to the latter, I propose to examine the process of forgetting by considering the engagement and affective relation of an embodied agent with her field of affordances. I suggest that, in the case of emotion-laden memories, the agent’s decoupling from some affordances of the environment might contribute to the process of forgetting, in that it would reduce the agent’s opportunities for situated episodic simulations. (shrink)

ABSTRACTFinance may suffer from institutional deformations that subordinate its distinctive goods to the pursuit of external goods, but this should encourage attempts to reform the institutionalization of finance rather than to reject its potential for virtuous business activity. This article argues that finance should be regarded as a domain-relative practice. Alongside management, its moral status thereby varies with the purposes it serves. Hence, when practitioners working in finance facilitate projects that create common goods, it allows them to develop virtues. This (...) argument applies MacIntyre’s widely acknowledged account of the relationship between practices and the development of virtues while questioning some of his claims about finance. It also takes issue with extant accounts of particular financial functions that have failed to identify the distinctive goods of financial practice. (shrink)

How should we characterize the nature of conscious occurrent thought? In the last few years, a rather unexplored topic has appeared in philosophy of mind: cognitive phenomenology or the phenomenal character of cognitive mental episodes. In this paper I firstly present the motivation for cognitive phenomenology views through phenomenal contrast cases, taken as a challenge for their opponents. Secondly, I explore the stance against cognitive phenomenology views proposed by Restrictivism, classifying it in two strategies, sensory restrictivism and accompanying states. On (...) the one hand, I problematize the role of attention adopted by sensory restrictivism and I present and discuss in detail an argument that defends the limitation of sensory phenomenology so as to explain the distinction between visual and cognitive mental episodes on the basis of immediate experience. On the other hand, I address accompanying states views by discussing the empirical studies of Hurlburt et al. (2006, 2008) that defend the existence of “unsymbolized thinking”. I present how they can be construed as evidence for cognitive phenomenology views and I dispel some problems that have been raised against its acceptance. I thus conclude that cognitive phenomenology views hold up well against the restrictivist positions considered. (shrink)

In the last decade, Systems Biology has emerged as a conceptual and explanatory alternative to reductionist-based approaches in molecular biology. However, the foundations of this new discipline need to be fleshed out more carefully. In this paper, we claim that a relational ontology is a necessary tool to ground both the conceptual and explanatory aspects of Systems Biology. A relational ontology holds that relations are prior—both conceptually and explanatory—to entities, and that in the biological realm entities are defined primarily by (...) the context they are embedded within—and hence by the web of relations they are part of. (shrink)

Name der Zeitschrift: Semiotica Jahrgang: 2018 Heft: 220 Seiten: 155-172.

Two arguments are offered here for postulating individual essences of concrete individuals on top of their sortal essences. One is the explanatory gap argument, the other draws on the analogy with the individual essences of events presupposed in single causal explanations. These arguments support qualitative individual essences with explanatory goals as opposed to hybrid impure relational essences accounting for origin and numerical identity. It is highlighted why origin properties as parts of impure relational essences do not yield genuine de re (...) constructions. The distinction between the two types of individual essences is traced back to the ambiguity of the very notion of individuation. (shrink)

In the last few decades, philosophy of science has increasingly focused on multilevel models and causal mechanistic explanations to account for complex biological phenomena. On the one hand, biological and biomedical works make extensive use of mechanistic concepts; on the other hand, philosophers have analyzed an increasing range of examples taken from different domains in the life sciences to test—support or criticize—the adequacy of mechanistic accounts. The article highlights some challenges in the elaboration of mechanistic explanations with a focus on (...) cancer research and neuropsychiatry. It jointly considers fields, which are usually dealt with separately, and keeps a close eye on scientific practice. The article has a twofold aim. First, it shows that identification of the explananda is a key issue when looking at dynamic processes and their implications in medical research and clinical practice. Second, it discusses the relevance of organizational accounts of mechanisms, and questions whether thorough self-sustaining mechanistic explanations can actually be provided when addressing cancer and psychiatric diseases. While acknowledging the merits of the wide ongoing debate on mechanistic models, the article challenges the mechanistic approach to explanation by discussing, in particular, explanatory and conceptual terms in the light of stances from medical cases. (shrink)

We investigate uniform interpolants in propositional modal logics from the proof-theoretical point of view. Our approach is adopted from Pitts’ proof of uniform interpolationin intuitionistic propositional logic [15]. The method is based on a simulation of certain quantifiers ranging over propositional variables and uses a terminating sequent calculus for which structural rules are admissible.

En este artículo defiendo la tesis de que la estética de la naturaleza puede ofrecer a la ética de la naturaleza uno de los mejores argumentos ecologistas. Creo que el valor estético de la naturaleza, tradicionalmente olvidado por la filosofía, puede revitalizar las discusiones que tienen lugar en la ética de la naturaleza, y permite enfocar de un modo nuevo la cuestión de si la naturaleza posee un valor intrínseco o un valor instrumental.

This paper proposes a new explanation for the oddness of presuppositional and negative islands, as well as the puzzling observation that these islands can be obviated by certain quantificational elements. The proposal rests on two independently motivated assumptions: (i) the idea that the domain of manners contains contraries and (ii) the notion that degree expressions range over intervals. It is argued that, given these natural assumptions, presuppositional and negative islands are predicted to lead to a presupposition failure in any context.

Two arguments are offered here for postulating individual essences of concrete individuals on top of their sortal essences. One is the explanatory gap argument, the other draws on the analogy with the individual essences of events presupposed in single causal explanations. These arguments support qualitative individual essences with explanatory goals as opposed to hybrid impure relational essences accounting for origin and numerical identity. It is highlighted why origin properties as parts of impure relational essences do not yield genuine de re (...) constructions. The distinction between the two types of individual essences is traced back to the ambiguity of the very notion of individuation. (shrink)

Within feminist theory and a wide range of social sciences, intersectionality has emerged as a key analytic framework, challenging paradigms that consider gender, race, class, sexuality, and other categories as separate and instead conceptualizing them as interconnected. This has led most authors to assume mutual constitution as the pertinent model, often without much scrutiny. In this essay we critically review the main senses of mutual constitution in the literature and challenge what we take to be a problematic assumption: the problem (...) of reification, here understood as the conceptualization of social categories as entities or objects. We then present the properties framework, together with the emergent experience view, which conceptualizes categories and social systems in a way that maintains their ontological specificity while allowing for their being deeply affected by each other. (shrink)

This paper aims to differentiate between lying and irony, typically addressed independently by philosophers and linguists, as well as to discuss the cases when deception co-occurs with, and capitalises on, irony or metaphor. It is argued that the focal distinction can be made with reference to Grice’s first maxim of Quality, whose floutings lead to overt untruthfulness, and whose violations result in covert untruthfulness. Both types of untruthfulness are divided into explicit and implicit subtypes depending on the level of meaning (...) on which they are manifest. Further, it is shown that deception may be based on irony or metaphor, which either promote deceptive implicatures or are deployed covertly. Finally, some argumentation is provided in favour of why these cases of deceiving can be conceptualised as lying. (shrink)

This philosophical-pragmatic paper discusses several forms of irony which rest on other figures of speech contingent on overt untruthfulness, namely the figures arising as a result of flouting the first maxim of Quality. It is argued that an ironic implicature may be piggybacked on another implicature, called “as if implicature”, originating from flouting the first maxim of Quality occasioned by metaphor. Metaphorical irony, which is subject to the irony-after-metaphor order of interpretation, exhibits a number of manifestations depending on the nature (...) and scope of irony, and the scope of the subordinate metaphor. On the other hand, rather than giving rise to an as if implicature distinct from the irony-based one, hyperbole and meiosis, which are inherently evaluative, most typically overlap with ironically evaluative expressions, promoting meiotic and hyperbolic irony, frequently considered by researchers to rely on flouting Quantity maxims. However, cases of independent use of hyperbole or meiosis in ironic environment are also possible. Such invite two levels of untruthfulness and two implicatures. (shrink)

We introduce the logic LRC, designed to describe and reason about agents’ abilities and capabilities in using resources. The proposed framework bridges two—up to now—mutually independent strands of literature: the one on logics of abilities and capabilities, developed within the theory of agency, and the one on logics of resources, motivated by program semantics. The logic LRC is suitable to describe and reason about key aspects of social behaviour in organizations. We prove a number of properties enjoyed by LRC and (...) its associated analytic calculus. These results lay at the intersection of the algebraic theory of unified correspondence and the theory of multitype calculi in structural proof theory. Case studies are discussed which showcase several ways in which this framework can be extended and enriched while retaining its basic properties, so as to model an array of issues, both practically and theoretically relevant, spanning from planning problems to the logical foundations of the theory of organizations. (shrink)

Hélène Cixous is more than an influential theorist. She is also a groundbreaking author and playwright. Combining an idiosyncratic mix of autobiographical and fictional narrative with a host of philosophical and poetic observations, Cixous's writing matches the kaleidoscopic nature of her thought, offering new ways of conceptualizing sex, relationships, identity, and the self, among other topics. Yet, as Jacques Derrida once observed, a "profound misunderstanding" hangs over the accomplishments of Cixous, with many believing the intellectual excelled only at theoretical exploration. (...) Providing a truly liberal selection of her writings from throughout her career, Marta Segarra rediscovers Cixous's acts of invention for a new generation to enjoy. Divided into thematic concerns, these works fully capture Cixous's genius for merging fiction, theory, and the experience of living. They discuss dreaming in the feminine, Algeria and Germany, love and the other, the animal, Derrida, and the theater. They defy classification, locking literature, philosophy, and psychoanalysis into thrilling new patterns of engagement. Whether readers are familiar with Cixous or are approaching her thought for the first time, all will find fresh perspectives on gender, fiction, drama, philosophy, religion, and the postcolonial. (shrink)