11 found
Martine C. de Vries [8]Martine de Vries [3]
  1.  13
    Standards of Practice in Empirical Bioethics Research: Towards a Consensus.Jonathan Ives, Michael Dunn, Bert Molewijk, Jan Schildmann, Kristine Bærøe, Lucy Frith, Richard Huxtable, Elleke Landeweer, Marcel Mertz, Veerle Provoost, Annette Rid, Sabine Salloch, Mark Sheehan, Daniel Strech, Martine de Vries & Guy Widdershoven - 2018 - BMC Medical Ethics 19 (1):68.
    Background This paper reports the process and outcome of a consensus finding project, which began with a meeting at the Brocher Foundation in May 2015. The project sought to generate and reach consensus on standards of practice for Empirical Bioethics research. The project involved 16 academics from 5 different European Countries, with a range of disciplinary backgrounds. Methods The consensus process used a modified Delphi approach. Results Consensus was reached on 15 standards of practice, organised into 6 domains of research (...)
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  2.  22
    Why is It Hard to Make Progress in Assessing Children’s Decision-Making Competence?Irma M. Hein, Pieter W. Troost, Alice Broersma, Martine C. De Vries, Joost G. Daams & Ramón J. L. Lindauer - 2015 - BMC Medical Ethics 16 (1):1.
    For decades, the discussion on children’s competence to consent to medical issues has concentrated around normative concerns, with little progress in clinical practices. Decision-making competence is an important condition in the informed consent model. In pediatrics, clinicians need to strike a proper balance in order to both protect children’s interests when they are not fully able to do so themselves and to respect their autonomy when they are. Children’s competence to consent, however, is currently not assessed in a standardized way. (...)
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  3.  58
    Informed Consent Instead of Assent is Appropriate in Children From the Age of Twelve: Policy Implications of New Findings on Children’s Competence to Consent to Clinical Research.Irma M. Hein, Martine C. De Vries, Pieter W. Troost, Gerben Meynen, Johannes B. Van Goudoever & Ramón J. L. Lindauer - 2015 - BMC Medical Ethics 16 (1):1-7.
    BackgroundFor many decades, the debate on children’s competence to give informed consent in medical settings concentrated on ethical and legal aspects, with little empirical underpinnings. Recently, data from empirical research became available to advance the discussion. It was shown that children’s competence to consent to clinical research could be accurately assessed by the modified MacArthur Competence Assessment Tool for Clinical Research. Age limits for children to be deemed competent to decide on research participation have been studied: generally children of 11.2 (...)
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  4.  86
    Reflective Equilibrium and Empirical Data: Third Person Moral Experiences in Empirical Medical Ethics.Martine de Vries & Evert van Leeuwen - 2010 - Bioethics 24 (9):490 - 498.
    In ethics, the use of empirical data has become more and more popular, leading to a distinct form of applied ethics, namely empirical ethics. This ‘empirical turn’ is especially visible in bioethics. There are various ways of combining empirical research and ethical reflection. In this paper we discuss the use of empirical data in a special form of Reflective Equilibrium (RE), namely the Network Model with Third Person Moral Experiences. In this model, the empirical data consist of the moral experiences (...)
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  5.  21
    Ethical Issues at the Interface of Clinical Care and Research Practice in Pediatric Oncology: A Narrative Review of Parents' and Physicians' Experiences.Martine C. de Vries, Mirjam Houtlosser, Jan M. Wit, Dirk P. Engberts, Dorine Bresters, Gertjan Jl Kaspers & Evert van Leeuwen - 2011 - BMC Medical Ethics 12 (1):18.
    BackgroundPediatric oncology has a strong research culture. Most pediatric oncologists are investigators, involved in clinical care as well as research. As a result, a remarkable proportion of children with cancer enrolls in a trial during treatment. This paper discusses the ethical consequences of the unprecedented integration of research and care in pediatric oncology from the perspective of parents and physicians.MethodologyAn empirical ethical approach, combining a narrative review of qualitative studies on parents' and physicians' experiences of the pediatric oncology research practice, (...)
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  6.  28
    A Case Against Something That is Not the Case: The Groningen Protocol and the Moral Principle of Non-Maleficence.Martine C. de Vries & A. A. Eduard Verhagen - 2008 - American Journal of Bioethics 8 (11):29-31.
  7.  20
    The Use of Dogmas in Pediatric Research Ethics.Martine C. de Vries - 2015 - American Journal of Bioethics 15 (11):18-19.
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  8.  10
    The Right to an Open Future Concerning Genetic Information.Annelien L. Bredenoord, Martine C. De Vries & Hans van Delden - 2014 - American Journal of Bioethics 14 (3):21-23.
  9.  9
    Participation in a Single-Blinded Pediatric Therapeutic Strategy Study for Juvenile Idiopathic Arthritis: Are Parents and Patient-Participants in Equipoise?Petra C. E. Hissink Muller, Bahar Yildiz, Cornelia F. Allaart, Danielle M. C. Brinkman, Marion van Rossum, Lisette W. A. van Suijlekom-Smit, J. Merlijn van den Berg, Rebecca ten Cate & Martine C. de Vries - 2018 - BMC Medical Ethics 19 (1):1-9.
    Background Genuine uncertainty on superiority of one intervention over the other is called equipoise. Physician-investigators in randomized controlled trials need equipoise at least in studies with more than minimal risks. Ideally, this equipoise is also present in patient-participants. In pediatrics, data on equipoise are lacking. We hypothesize that 1) lack of equipoise at enrolment among parents may reduce recruitment; 2) lack of equipoise during participation may reduce retention in patients assigned to a less favoured treatment-strategy. Methods We compared preferences of (...)
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    A Case Against Something That is Not the Case: The Groningen Protocol and the Moral Principle of Non-Maleficence.Martine C. de Vries & Aa Eduard Verhagen - 2008 - American Journal of Bioethics 8 (11):29 - 31.
  11.  18
    On Classifying the Field of Medical Ethics.Kristine Bærøe, Jonathan Ives, Martine de Vries & Jan Schildmann - 2017 - BMC Medical Ethics 18 (1):30.
    In 2014, the editorial board of BMC Medical Ethics came together to devise sections for the journal that would give structure to the journal help ensure that authors’ research is matched to the most appropriate editors and help readers to find the research most relevant to them. The editorial board decided to take a practical approach to devising sections that dealt with the challenges of content management. After that, we started thinking more theoretically about how one could go about classifying (...)
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