Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Thomas L. Kane, a crusader for antislavery, women's rights, and the downtrodden, rose to prominence in his day as the most ardent and persuasive defender of Mormons' religious liberty. Though not a Mormon, Kane sought to defend the much-reviled group from the "Holy War" waged against them by evangelical America. His courageous personal intervention averted a potentially catastrophic bloody conflict between federal troops and Mormon settlers in the now nearly forgotten Utah War of 1857-58. Drawing on extensive, newly (...) available archives, this book is the first to tell the full story of Kane's extraordinary life. The book illuminates his powerful Philadelphia family, his personal life and eccentricities, his reform achievements, his place in Mormon history, and his career as a Civil War general. Further, the book revises previous understandings of nineteenth-century reform, showing how Kane and likeminded others fused Democratic Party ideology, anti-evangelicalism, and romanticism. (shrink)

A number of philosophers and theologians have recently challenged the common assumption that it would be impossible for God to cause humans actions which are free in the libertarian or incompatibilist sense. Perhaps the most sophisticated version of this challenge is due to W. Matthews Grant. By offering a detailed account of divine causation, Grant argues that divine universal causation does not preclude humans from being ultimately responsible for their actions, nor free according to typical libertarian accounts. Here, we argue (...) that the kind of divine universal causation that Grant proposes is incompatible with a plausible interpretation of Robert Kane’s influential conception of ultimate responsibility. This conclusion is significant since Grant seeks to harmonize his divine causal account with Kane’s articulation of ultimate responsibility. (shrink)

Robert Kane provides a critical overview of debates about free will of the past half century, relating this recent inquiry to the broader history of the free will issue and to vital currents of twentieth century thought. Kane also defends a traditional libertarian or incompatibilist view of free will, employing arguments that are both new to philosophy and that respond to contemporary developments in physics and biology, neuro science, and the cognitive and behavioral sciences.

Reason's Traces is a collection of essays by one of the foremost authorities on Indian and Tibetan Buddhism.

In a recent paper in this journal, “How should libertarians conceive of the location and role of indeterminism?” Christopher Evan Franklin critically examines my libertarian view of free will and attempts to improve upon it. He says that while Kane's influential [view] offers many important advances in the development of a defensible libertarian theory of free will and moral responsibility … [he made] “two crucial mistakes in formulating libertarianism” – one about the location of indeterminism, the other about its (...) role – “both of which have helped fan the flame of the luck argument”. In this paper, I respond to Franklin's criticisms, arguing that, so far from making it significantly more difficult to answer objections about luck and control, as he claims, giving indeterminism the location and role I do makes it possible to answer such objections and many other related objections to libertarian free will. A central theme of this paper will emerge in my responses: In order to make sense of freedom of will... (shrink)

Amid the unrest, dislocation, and uncertainty of seventeenth-century Europe, readers seeking consolation and assurance turned to philosophical and scientific books that offered ways of conquering fears and training the mind—guidance for living a good life. _The Good Life in the Scientific Revolution_ presents a triptych showing how three key early modern scientists, René Descartes, Blaise Pascal, and Gottfried Leibniz, envisioned their new work as useful for cultivating virtue and for pursuing a good life. Their scientific and philosophical innovations stemmed in (...) part from their understanding of mathematics and science as cognitive and spiritual exercises that could create a truer mental and spiritual nobility. In portraying the rich contexts surrounding Descartes’ geometry, Pascal’s arithmetical triangle, and Leibniz’s calculus, Matthew L. Jones argues that this drive for moral therapeutics guided important developments of early modern philosophy and the Scientific Revolution. (shrink)

A prima facie plausible and widely held view in epistemology is that the epistemic standards governing the acquisition of testimonial knowledge are stronger than the epistemic standards governing the acquisition of perceptual knowledge. Conservatives about testimony hold that we need prior justification to take speakers to be reliable but recognise that the corresponding claim about perception is practically a non-starter. The problem for conservatives is how to establish theoretically significant differences between testimony and perception that would support asymmetrical epistemic standards. (...) In this paper I defend theoretical symmetry of testimony and perception on the grounds that there are no good reasons for taking these two belief forming methods to have significant theoretical differences. I identify the four central arguments in defence of asymmetry and show that in each case either they fail to establish the difference that they purport to establish or they establish a difference that is not theoretically significant. (shrink)

In this little but profound volume, Robert Kane and Carolina Sartorio debate a perennial question: Do We Have Free Will? Short, lively and accessible, the debate showcases diverse and cutting-edge work on free will.

Over the past three decades, I have been developing a distinctive view of free will motivated by a desire to reconcile a non-determinist view of free will with modern science as well as with recent developments in philosophy. A view of free will of the kind I defend did not exist in a developed form before the 1980s, but is now discussed in the philosophical literature as one of three chief options an incompatibilist or libertarian view of free will might (...) take. As such, this view has been the subject of much recent discussion. In this paper, I explain and defend my view of free will, and answer recent criticisms of it. Some of these criticisms are made by Robert Allen in his paper “Self-forming Actions,” a contribution to the seminar of which the present paper is a part. I also respond to Katherin Rogers’ contribution to this seminar “Libertarianism in Kane and Anselm.” Her book, Anselm on Freedom, argues that Anselm defended a unique libertarian view of free will, avoiding both Pelagianism and Augustine’s later compatibilism, a view that she argues has affinities to my view of free will. I also discuss these affinities to Anselm in my paper and their theological and well as philosophical implications. (shrink)

In recent decades, scholars of Buddhist philosophy have frequently treated the Trisvabhāvanirdeśa, or “Teaching of the Three Natures,” attributed to Vasubandhu, as an authentic and authoritative representation of that celebrated thinker’s mature work within the Yogācāra tradition. However, serious questions may be posed concerning the status and authority of the TSN within Yogācāra, its true authorship, and the relation of its contents to trends in early Yogācāra thought. In the present article, we review the actual state of our knowledge of (...) the TSN’s possible origins, considering, too, the implications this may have for contemporary treatments thereof. (shrink)

In this paper, I argue for three claims. The first is that the difference between analog and digital representation lies in the format and not the medium of representation. The second is that whether a given system is analog or digital will sometimes depend on facts about the user of that system. The third is that the first two claims are implicit in Haugeland's (1998) account of the distinction.

The term "human dignity" is the source of considerable confusion in contemporary bioethics. It has been used by Kantians to refer to autonomy, by others to refer to the sanctity of life, and by still others to refer—albeit obliquely—to an important but infrequently discussed set of human goods. In the first part of this article, I seek to disambiguate the notion of human dignity. The second part is a defense of the philosophical utility of such a notion; I argue that (...) there is nothing implausible about appealing to a deontological "principle of dignity" to solve bioethical problems, especially those concerning the development of new biotechnologies. There may, however, be problems associated with any attempt to use dignity as a basis for public policy. This sort of worry is explained and briefly addressed in the final section. (shrink)

Critics of theological accounts of the nature of morality have argued that such accounts must be rejected, even by theists, because such accounts (i) have the unacceptable implication that nothing is morally wrong in possible worlds in which atheism is true, (ii) render the substantive content of morality arbitrary, and (iii) make it impossible or redundant to attribute moral properties to God or God’s actions. I argue that none of these criticisms constitute good reason for theists to abandon theological accounts (...) of the nature of morality. (shrink)

Thanks to the international celebrity of the present Dalai Lama, Tibetan Buddhism is attracting more attention than at any time in its history. Although there have been numerous specialist studies of individual Tibetan texts, however, no scholarly work has as yet done justice to the rich variety of types of Tibetan discourse. This book fills this lacuna, bringing to bear the best methodological insights of the contemporary human sciences, and at the same time conveying to non-specialist readers an impression of (...) the broad domain of Tibetan religious and philosophical thought. Ranging widely over the immense corpus of Tibetan literature, Kapstein brilliantly illuminates many of the distinctive Tibetan contributions and points out some of the insights. (shrink)

The project of comparing Stoicism and Buddhism may appear to be an improbable one. While the latter determines that we strive for an enlightenment that contributes to the liberation of all living beings, the doctrines of the former would seem to entail that this is impossible. Though both strongly affirm principles of causality and cyclicity in the constitution of the world, Buddhism apparently grants considerably more freedom of human agency than does Stoicism. Their conception of eternal return in the strict (...) and literal sense is foreign to the Buddhist notion of the bodhisattva's ongoing spiritual progress through numberless lives. These distinctions, moreover, sometimes issue in markedly different ethical orientations: the Buddhist elevation of compassion in the constellation of cardinal virtues finds its Stoic pendant in a more restrained attitude of commiseration. (shrink)

Most philosophical defences of the state’s right to exclude immigrants derive their strength from the normative importance of self-determination. If nation-states are taken to be the political institutions of a people, then the state’s right to exclude is the people’s right to exclude – and a denial of this right constitutes an abridgement of self-determination. In this paper, I argue that this view of self-determination does not cohere with a group-agency view of nation-states. On the group-agency view that I defend, (...) a nation-state is the kind of group-agent that does not supervene on the intentionality of member/citizens. If we think that a nation-state is an intentional group-agent in its own right, then we should think that self-determination resides with the institutions of the state rather than with the citizens. If nation-states do not supervene on the intentionality of citizens, then it is unclear why citizens might have the right to control membership in the state as a feature of self-determination. (shrink)

The thesis that meaning is normative has come under much scrutiny of late. However, there are aspects of the view that have received comparatively little critical attention which centre on meaning’s capacity to guide and justify linguistic action. Call such a view ‘justification normativity’. I outline Zalabardo’s account of JN and his corresponding argument against reductive-naturalistic meaning-factualism and argue that the argument presents a genuine challenge to account for the guiding role of meaning in linguistic action. I then present a (...) proposal regarding how this challenge may be met. This proposal is then compared to recent work by Ginsborg, who has outlined an alternative view of the normativity of meaning that explicitly rejects the idea that meanings guide and justify linguistic use. I outline how Ginsborg utilises this notion of normativity in order to provide a positive account of what it is to mean something by an expression which is intended to serve as a r.. (shrink)

And the venerable Nāgasena said to Milinda the king: “You, Sire, have been brought up in great luxury, as beseems your noble birth. If you were to walk this dry weather on the hot and sandy ground, trampling under foot the gritty, gravelly grains of the hard sand, your feet would hurt you. And as your body would be in pain, your mind would be disturbed, and you would experience a sense of bodily suffering. How then did you come, on (...) foot, or in a chariot?”. (shrink)

Characterizing different kinds of representation is of fundamental importance to cognitive science, and one traditional way of doing so is in terms of the analog–digital distinction. Indeed the distinction is often appealed to in ways both narrow and broad. In this paper I argue that the analog–digital distinction does not apply to representational schemes but only to representational systems, where a representational system is constituted by a representational scheme and its user, and that whether a representational system is analog or (...) non-analog depends on facts about that user. This aspect of the distinction has gone unnoticed, and I argue that the failure to notice it can be an impediment to scientific progress. (shrink)

We live in a world that is increasingly shaped by and bathed in science, with most scientific progress occurring in the past century, and much of it in the past few decades. Yet, several authors have puz- zled over the observation that modern societies are also characterized by a high degree of belief in a variety of pseudoscientific claims that have been thoroughly debunked or otherwise discarded by scientists (Anonymous, 2001; Ede, 2000).

A recent movement within political philosophy called luck egalitarianism has attempted to synthesize the right’s regard for responsibility with the left’s concern for equality. The original motivation for subscribing to luck egalitarianism stems from the belief that one’s success in life ought to reflect one’s own choices and not brute luck. Luck egalitarian theorists differ in the decision procedures that they propose, but they share in common the general approach that we ought to equalize individuals with respect to brute luck (...) so that differences in distribution are only a consequence of the responsible choices that individuals make. I intend to show that through the application of its own distributive procedures, the interpersonal luck egalitarian approach actually undermines its original motivation by making the lives of individuals subject to brute luck. I propose two alternative methods that the luck egalitarian could use to prevent the problems suffered by the interpersonal luck egalitarian standard. (shrink)

"On the ... issue of our pluralistic age -- whether we can continue to believe in absolute value -- Robert Kane has written the most helpful discussion I know.

The decision of the German regional court in Cologne on 26 June 2012 to prohibit the circumcision of minors is important insofar as it recognises the qualitative similarities between the practice and other prohibited invasive rites, such as female genital cutting. However, recognition of similarity poses serious questions with regard to liberal public policy, specifically with regard to the exceptionalist treatment demanded by certain circumcising groups. In this paper, I seek to advance egalitarian means of dealing with invasive rites which (...) take seriously cultural diversity, minimise harm and place responsibility for the burdens and consequences of beliefs upon those who promote practices. (shrink)

Though Stcherbatsky was eager to present Buddhist logic as broadly consistent with an early twentieth‐century European vision of philosophical research as critical reason unbridled by the presuppositions of religion, this was certainly not the sole source of the tension found in his words. There were at least three major trends in relation to this problematic that can be identified within Buddhist textual traditions. This chapter explores somewhat the elaboration of these alternatives, both in traditional Buddhist and in contemporary academic writings. (...) Against those who have held, however, that the available evidence does not permit us to conclude that there was any interesting relationship between the Buddhist pramāna tradition and those Buddhist intellectual practices that we might characterize as “spiritual exercise,” the author would argue that the very presence of contestation about this within the tradition itself sufficiently demonstrates that the possibilities of such a relationship were well understood. (shrink)

A certain brand of skeptical argument appeals to the thought that our inability to subjectively discriminate between competing hypotheses means that we are unwarranted in believing in either. Externalists respond by pointing out that such arguments depend on an internalist conception of warrant that we would do well to reject. This strategy has been criticised by Crispin Wright who argues that if we pursue the implications of externalism sufficiently far we find that it is ultimately unstable or incoherent. I first (...) rehearse the simple externalist anti-skeptical position. I then present Wright’s argument for the externalist instability, offering a clearer way of understanding its central claim. Finally, I show that the instability in fact arises due to hidden internalist assumptions about evidence and that rid of these assumptions the externalist position is stable after all. (shrink)

In accord with the theme of the present volume on , it is not so much the aim of this essay to provide a detailed account of particular lines of argument, as it is to suggest something of the manner in which so-called 'Buddhist idealism' unfolded as a tradition not just for Buddhists, but within Indian philosophy more generally. Seen from this perspective, Buddhist idealism remained a current within Indian philosophy long after the demise of Buddhism in India, in about (...) the twelfth century, and endured in some respects at least until the Mughal age, when the last thinker to be examined here, the Jain teacher Yaśovijaya, was active. (shrink)

Modernity has challenged the ancient ideal of a universal quest for wisdom, and today's world of conflicting cultures and values has raised further doubts regarding the possibility of objective ethical standards. Robert Kane refocuses the debate on the philosophical quest for wisdom, and argues that ethical principles about right action and the good life can be seen to emerge from that very quest itself. His book contends that the search for wisdom involves a persistent striving to overcome narrowness of (...) vision that comes from the inevitable limitations of finite points of view. When applied to questions of value and the good life, this striving has ethical implications about the way we should treat ourselves and others. This study argues for the merits of this central thesis against alternative theories in contemporary normative ethics, and discusses its practical applications for social ethics, political philosophy, law and moral education. (shrink)