A number of experiences have demonstrated how digital solutions are effective in improving quality of life (QoL) and health outcomes for older adults. Smart Health Age-Friendly Environments (SHAFE) is a new concept introduced in Europe since 2017 that combines the concept of Age-Friendly Environments with Information Technologies, supported by health and community care to improve the health and disease management of older adults and during the life-course. This chapter aims to provide an initial overview of the experiences available not only (...) in Europe, based on the research work of the participants of the International Interdisciplinary Network on Health and Well-being in an Age-Friendly Digital World (NET4Age-Friendly), which could be of interest to preventive, health and social authorities. The chapter reports good practices, pain points, and bottlenecks that may require a collaborative, interdisciplinary research approach to facilitate the transformations towards smart, sustainable, health and age-friendly cities and communities. (shrink)

O objetivo do presente artigo é analisar o quanto o chamado idealismo italiano de Croce e Gentile são, em verdade, dependentes da concepção religiosa italiana. Para tanto, nos deteremos, na primeira parte do nosso trabalho, principalmente numa análise das teses de Maurizio Viroli. Já no segundo parte do nosso artigo nos deteremos na análise dessa temática dentro do conceito de religião da liberdade em Croce. Assim, após tal inventário, teceremos nossas conclusões.

The author intends to show how the criticism of Maurizio Ferraris to the correspon-dence of ontology and epistemology, which developed in the modern age, does not consider that the Thought of the transcendentalism is not the thought of the everyday language but rather a limiting concept. Therefore, the fair criticism to the pragmatism and to the post-modernism in the name of the “reality principle” cannot involve the ideas of the so-called idealists (Kant, Hegel, Gentile, Croce): to conceive the (...) reality as history, as the idealists do, has important ethical implications. (shrink)

This highly acclaimed volume brings together some of the world's foremost historians of ideas to consider Machiavelli's political thought in the larger context of the European republican tradition, and the image of Machiavelli held by other republicans. An international team of scholars from a variety of disciplinary backgrounds (notably law, philosophy, history and the history of political thought) explore both the immediate Florentine context in which Machiavelli wrote, and the republican legacy to which he contributed.

Ethical approval must be obtained before medical research can start. We describe the differences in EA for an pseudonymous, non-interventional, observational European study. Sixteen European national coordinators of the international study on very old intensive care patients answered an online questionnaire concerning their experience getting EA. N = 8/16 of the NCs could apply at one single national ethical committee, while the others had to apply to various regional ECs and/or individual hospital institutional research boards. The time between applying for (...) EA and the first decision varied between 7 days and 300 days. In 9/16 informed consent from the patient was not deemed necessary; in 7/16 informed consent was required from the patient or relatives. The upload of coded data to a central database required additional information in 14/16. In 4/16 the NCs had to ask separate approval to keep a subject identification code list to de-pseudonymize the patients if questions would occur. Only 2/16 of the NCs agreed that informed consent was necessary for this observational study. Overall, 6/16 of the NCs were satisfied with the entire process and 8/16 were unsatisfied. 11/16 would welcome a European central EC that would judge observational studies for all European countries. Variations in the process and prolonged time needed to get EA for observational studies hampers inclusion of patients in some European countries. This might have a negative influence on the external validity. Further harmonization of ethical approval process across Europe is welcomed for low-risk observational studies. Getting ethical approval for low-risk, non-interventional, observational studies varies enormously across European countries. (shrink)

IntroductionAnimal Assisted Interventions are increasingly common in pediatric care settings as a means to promote the physical, mental, and emotional well-being of hospitalized children and adolescents.ObjectivesThe aim of this work was to review published studies implementing AAIs in hospital settings and to assess the effects of AAIs on the biobehavioral response to stress and pain, social behavior, quality of life and level of satisfaction with hospitalization in children and adolescents. Stress and burden, quality of life, mood and level of satisfaction (...) with hospitalization in parents/caregivers as well as stress and burden, perception of the work environment and job satisfaction in hospital staff were also reviewed.MethodsAll published studies reporting quantitative assessments were systematically searched using PubMed, Scopus, ProQuest and Web of Science databases in accordance with PRISMA guidelines. The aim was to identify studies examining the effects of AAIs on behavioral, psychological and physiological responses to stress in children and adolescents formally admitted to a hospital for a stay, as well as in those undergoing a visit for treatments or medical examinations.ResultsOf the 350 studies screened, 21 were eligible for inclusion. Most of them focused on stress, pain, and anxiety reduction in pediatric patients, and used both physiological parameters and behavioral and psychological observations/scales. All studies employed dogs. Results show the potential of AAIs to reduce anxiety and behavioral distress in pediatric patients while acting on physiological measures associated with arousal.ConclusionAlthough further, more rigorous studies are still needed, the findings of this review may have implications for clinical practices suggesting appropriate planning of AAIs by pediatric healthcare professionals.Systematic Review Registration[https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=178993], identifier [CRD42020178993]. (shrink)

Although living conditions have improved throughout history, protest, at least in the last few decades, seems to have increased to the point of becoming a normal phenomenon in modern societies. Contributors to this volume examine how and why this is the case and argue that although problems such as poverty, hunger, and violations of democratic rights may have been reduced in advanced Western societies, a variety of other problems and opportunities have emerged and multiplied the reasons and possibilities for protest.

We axiomatize, in the multidimensional case, a social evaluation function that can accommodate a natural Pigou–Dalton principle and correlation increasing majorization. This is performed by building upon a simple class of inframodular functions proposed by Müller and Scarsini under risk.

The concept of the soul, one of the greatest 'inventions' of Greek philosophy, which crossed the whole history of the Western civilisation, was defined in its fundamental philosophical features by Plato. Developing the numerous issues naturally linked to this concept, Plato's thought does not only focus on metaphysical and religious themes, but also to all issues related to spirituality and the human psyche, including their ethical consequences. Therefore, the concept of soul opens the door to an endless process involving the (...) analysis of a subject's interiority. It is not by chance, that this Platonic theme recurs in many texts and even represents the backbone of whole dialogues. In this collection, some of the most important contemporary Platonic scholars looked at these complex philosophical issues from innovative perspectives, especially with regard to texts that previously were either underestimated or largely ignored. This perspective gives the reader a chance to evaluate the hermeneutic power of different approaches and interpretations of Plato's texts, revaluating as well the richness of Plato's contribution to questions that have been received and developed in contemporary philosophical reflections. (shrink)

Nationalism and patriotism are two of the most powerful forces shaping world history. In this paperback edition of a highly successful, wide-ranging study, Maurizio Viroli shows exactly why patriotism is a political virtue and nationalism a political vice.

1. Dialettica, metafisica e cosmologia -- Dall'anima alla prassi etica e politica.

In this essay I try to give some overall statements in order to show that new realism is to be understood as a kind of positive philosophy. Against constructivism, I argue that there is a prevalence of the objects themselves on our understanding of them because reality offers a resistance to our attempt to grasp it depending on its level of dependence from our own understanding, which is different in the case of natural objects, ideal object and social object. This (...) negativity leads to an ontological necessity of facticity. In the second part of this paper I will describe – through the exposition of three key concepts of new realism, i.e. “unamendability”, “interaction” and “affordance” – an ascending path for which the negative and the resistance turn into positivity. (shrink)

Chapter 1st of the book. This chapter explores the fundamental ambiguity of the concept of plasticity – between openness and determination, change and stabilization of forms. This pluralism of meanings is used to unpack different instantiations of corporeal plasticity across various epochs, starting from ancient and early modern medicine, particularly humouralism. A genealogical approach displaces the notion that plasticity is a unitary phenomenon, coming in the abstract, and illuminates the unequal distribution of different forms of plasticities across social, gender, and (...) ethnic groups. Taking a longer view of the plastic body as a ubiquitous belief in traditions predating and coexisting with modern medicine will help contextualize the seeming radicalism of today’s turn to permeability and the exceptionalism of Western findings. By highlighting the complex biopolitical usages of plasticity in the past, the chapter warns against simplistic appropriations of the term in contemporary body/world configurations driven by findings in neuroscience, epigenetics and microbiomics. (shrink)

This book studies a central but hitherto neglected aspect of Rousseau's political thought: the concept of social order and its implications for the ideal society which he envisages. The antithesis between order and disorder is a fundamental theme in Rousseau's work, and the author takes it as the basis for this study. In contrast with a widely held interpretation of Rousseau's philosophy, Professor Viroli argues that natural and political order are by no means the same for Rousseau. He explores the (...) differences and interrelations between the different types of order which Rousseau describes, and shows how the philosopher constructed his final doctrine of the just society, which can be based only on every citizen's voluntary and knowing acceptance of the social contract and on the promotion of virtue above ambition. The author also shows the extent of Rousseau's debt to the republican tradition, and above all to Machiavelli, and revises the image of Rousseau as a disciple of the natural-law school. (shrink)

The debtor-creditor relation, which is at the heart of this book, sharpens mechanisms of exploitation and domination indiscriminately, since, in it, there is no distinction between workers and the unemployed, consumers and producers, working and non-working populations, between retirees and welfare recipients. They are all "debtors," guilty and responsible in the eyes of capital, which has become the Great, the Universal, Creditor.--from The Making of the Indebted Man Debt -- both public debt and private debt Has become a major concern (...) of economic and political leaders. In The Making of the Indebted Man, Maurizio Lazzarato shows that, far from being a threat to the capitalist economy, debt lies at the very core of the neoliberal project. Through a reading of Karl Marx's lesser-known youthful writings on John Mill, and a rereading of writings by Friedrich Nietzsche, Gilles Deleuze, Felix Guattari, and Michel Foucault, Lazzarato demonstrates that debt is above all a political construction, and that the creditor/debtor relation is the fundamental social relation of Western societies.Debt cannot be reduced to a simple economic mechanism, for it is also a technique of "public safety" through which individual and collective subjectivities are governed and controlled. Its aim is to minimize the uncertainty of the time and behavior of the governed. We are forever sinking further into debt to the State, to private insurance, and, on a more general level, to corporations. To insure that we honor our debts, we are at once encouraged and compelled to become the "entrepreneurs" of our lives, of our "human capital." In this way, our entire material, psychological, and affective horizon is upended and reconfigured. How do we extricate ourselves from this impossible situation? How do we escape the neoliberal condition of the indebted man? Lazzarato argues that we will have to recognize that there is no simple technical, economic, or financial solution. We must instead radically challenge the fundamental social relation structuring capitalism: the system of debt. (shrink)

This article sets the stage for a genealogy of the postgenomic body. It starts with the current transformative views of epigenetics and microbiomics to offer a more pluralistic history in which the ethical problem of how to live with a permeable body – that is plasticity as a form of life – is pervasive in traditions pre-dating and coexisting with modern biomedicine (particularly humoralism in its several ramifications). To challenge universalizing narratives, I draw on genealogical method to illuminate the unequal (...) distribution of plasticity across gender and ethnic groups. Finally, after analysing postgenomics as a different thought-style to genomics, I outline some of its implications for notions of plasticity. I argue that postgenomic plasticity is neither a modernistic plasticity of instrumental control of the body nor a postmodernist celebration of endless potentialities. It is instead closer to an alter-modernistic view that disrupts clear boundaries between openness and determination, individual and community. (shrink)

A history of colonization inflicts psychological, physical, and structural disadvantages that endure across generations. For an increasing number of Indigenous Australians, environmental epigenetics offers an important explanatory framework that links the social past with the biological present, providing a culturally relevant way of understanding the various intergenerational effects of historical trauma. In this paper, we critically examine the strategic uptake of environmental epigenetics by Indigenous researchers and policy advocates. We focus on the relationship between epigenetic processes and Indigenous views of (...) Country and health—views that locate health not in individual bodies but within relational contexts of Indigenous ontologies that embody interconnected environments of kin/animals/matter/bodies across time and space. This drawing together of Indigenous experience and epigenetic knowledge has strengthened calls for action including state-supported calls for financial reparations. We examine the consequences of this reimagining of disease responsibility in the context of “strategic biological essentialism,” a distinct form of biopolitics that, in this case, incorporates environmental determinism. We conclude that the shaping of the right to protection from biosocial injury is potentially empowering but also has the capacity to conceal forms of governance through claimants’ identification as “damaged,” thus furthering State justification of biopolitical intervention in Indigenous lives. (shrink)

An analysis of how capitalism today produces subjectivity like any other “good,” and what would allow us to escape its hold. “Capital is a semiotic operator”: this assertion by Félix Guattari is at the heart of Maurizio Lazzarato's Signs and Machines, which asks us to leave behind the logocentrism that still informs so many critical theories. Lazzarato calls instead for a new theory capable of explaining how signs function in the economy, in power apparatuses, and in the production of (...) subjectivity. Moving beyond the dualism of signifier and signified, Signs and Machines shows how signs act as “sign-operators” that enter directly into material flows and into the functioning of machines. Money, the stock market, price differentials, algorithms, and scientific equations and formulas constitute semiotic “motors” that make capitalism's social and technical machines run, bypassing representation and consciousness to produce social subjections and semiotic enslavements. Lazzarato contrasts Deleuze and Guattari's complex semiotics with the political theories of Jacques Rancière, Antonio Negri and Michael Hardt, Paolo Virno, and Judith Butler, for whom language and the public space it opens still play a fundamental role. Lazzarato asks: What are the conditions necessary for political and existential rupture at a time when the production of subjectivity represents the primary and perhaps most important work of capitalism? What are the specific tools required to undo the industrial mass production of subjectivity undertaken by business and the state? What types of organization must we construct for a process of subjectivation that would allow us to escape the hold of social subjection and machinic enslavement? In addressing these questions, Signs and Machines takes on a task that is today more urgent than ever. (shrink)

As space travel and intentions to colonise other planets are becoming the norm in public debate and scholarship, we must also confront the technical and survival challenges that emerge from these hostile environments. This paper aims to evaluate the various arguments proposed to meet the challenges of human space travel and extraterrestrial planetary colonisation. In particular, two primary solutions have been present in the literature as the most straightforward solutions to the rigours of extraterrestrial survival and flourishing: (1) geoengineering, where (...) the environment is modified to become hospitable to its inhabitants, and (2) human (bio)enhancement where the genetic heritage of humans is modified to make them more resilient to the difficulties they may encounter as well as to permit them to thrive in non-terrestrial environments. Both positions have strong arguments supporting them but also severe philosophical and practical drawbacks when exposed to different circumstances. This paper aims to show that a principled stance where one position is accepted wholesale necessarily comes at the opportunity cost of the other where the other might be better suited, practically and morally. This paper concludes that case-by-case evaluations of the solutions to space travel and extraterrestrial colonisation are necessary to ensure moral congruency and the survival and flourishing of astronauts now and into the future. (shrink)

Mirko Garasic (2021) argued that space travel and, by extension, the colonization of other planets could morally justify using technologies and interventions capable of profoundly modifying the characteristics of astronauts and future Martian generations. According to Garasic, however, the fact that space interventions such as human (bio)enhancement or reproductive technologies such as artificial wombs may be morally justified does not mean that they are morally acceptable technologies to be used on Earth as well. Garasic’s thesis is that we should resist (...) the temptation to establish or reinforce a continuity between the ethical standards that apply to space travel and those that apply on Earth because what applies in space (or on other planets) does not necessarily apply to our planet. Garasic argues that in space, genetic enhancement interventions are morally acceptable, as they are essential for survival. On Earth, however, we can survive even without any form of (bio)enhancement. In a previous article (2022), we presented several arguments against Garasic’s thesis regarding the exceptional morality of what is morally acceptable in space. In this article, we examine and reply to Garasic (2022), showing that he fails to defend his thesis from the objections we previously advanced. Garasic’s mistakes are: (1) assuming nature (and consequently what is “natural”) as a normative point of reference which allows establishing what is moral and what is not moral; (2) defending the choices concerning reproduction as an insufficiently demanding and therefore unsatisfactory moral principle (according to Garasic we should not bring into the world people who can have a quality of life or a condition of well-being superior to mere survival); and finally (3) of not explaining clearly what it means to defend a principle of moral exceptionalism for space travel (Garasic does not explain whether this position applies to any behavior, for which what on Earth is a virtue, in space is a vice or is not a general principle, but he makes this case only for enhancement and reproductive technologies). Through our analysis, we not only refute Garasic’s position but also show that any attempt to address space travel issues as “special” moral issues faces several difficulties and, ultimately, is doomed to failure. (shrink)

The rise of molecular epigenetics over the last few years promises to bring the discourse about the sociality and susceptibility to environmental influences of the brain to an entirely new level. Epigenetics deals with molecular mechanisms such as gene expression, which may embed in the organism “memories” of social experiences and environmental exposures. These changes in gene expression may be transmitted across generations without changes in the DNA sequence. Epigenetics is the most advanced example of the new postgenomic and context-dependent (...) view of the gene that is making its way into contemporary biology. In my article I will use the current emergence of epigenetics and its link with neuroscience research as an example of the new, and in a way unprecedented sociality of contemporary biology. After a review of the most important developments of epigenetic research, and some of its links with neuroscience, in the second part I reflect on the novel challenges that epigenetics presents for the social sciences for a re-conceptualization of the link between the biological and the social in a postgenomic age. Although epigenetics remains a contested, hyped, and often uncritical terrain, I claim that especially when conceptualized in broader non-genecentric frameworks,. (shrink)

Maurizio Ferraris explores how, through the reading of Proust's _In Search of Lost Time_, one can explore memory, art, and society, using the book as a guide for living life.