8 found
Megan Campbell [4]Megan M. Campbell [2]Megan J. Campbell [1]Megan E. J. Campbell [1]
  1.  84
    Obtaining informed consent for genomics research in Africa: analysis of H3Africa consent documents.Nchangwi Syntia Munung, Patricia Marshall, Megan Campbell, Katherine Littler, Francis Masiye, Odile Ouwe-Missi-Oukem-Boyer, Janet Seeley, D. J. Stein, Paulina Tindana & Jantina de Vries - 2016 - Journal of Medical Ethics 42 (2):132-137.
    Background The rise in genomic and biobanking research worldwide has led to the development of different informed consent models for use in such research. This study analyses consent documents used by investigators in the H3Africa (Human Heredity and Health in Africa) Consortium. Methods A qualitative method for text analysis was used to analyse consent documents used in the collection of samples and data in H3Africa projects. Thematic domains included type of consent model, explanations of genetics/genomics, data sharing and feedback of (...)
    Direct download (8 more)  
    Export citation  
    Bookmark   19 citations  
  2.  63
    Exploring researchers’ experiences of working with a researcher-driven, population-specific community advisory board in a South African schizophrenia genomics study.Megan M. Campbell, Ezra Susser, Jantina de Vries, Adam Baldinger, Goodman Sibeko, Michael M. Mndini, Sibonile G. Mqulwana, Odwa A. Ntola, Raj S. Ramesar & Dan J. Stein - 2015 - BMC Medical Ethics 16 (1):1-9.
    BackgroundCommunity engagement within biomedical research is broadly defined as a collaborative relationship between a research team and a group of individuals targeted for research. A Community Advisory Board is one mechanism of engaging the community. Within genomics research CABs may be particularly relevant due to the potential implications of research findings drawn from individual participants on the larger communities they represent. Within such research, CABs seek to meet instrumental goals such as protecting research participants and their community from research-related risks, (...)
    Direct download (6 more)  
    Export citation  
    Bookmark   9 citations  
  3.  10
    The high costs of getting ethical and site-specific approvals for multi-centre research.Nicholas Graves, Brett G. Mitchell, Anne Gardner, Katie Page, Lisa Hall, Alison Farrington, Carla Shield, Megan J. Campbell & Adrian G. Barnett - 2016 - Research Integrity and Peer Review 1 (1).
    BackgroundMulti-centre studies generally cost more than single-centre studies because of larger sample sizes and the need for multiple ethical approvals. Multi-centre studies include clinical trials, clinical quality registries, observational studies and implementation studies. We examined the costs of two large Australian multi-centre studies in obtaining ethical and site-specific approvals.MethodsWe collected data on staff time spent on approvals and expressed the overall cost as a percent of the total budget.ResultsThe total costs of gaining approval were 38 % of the budget for (...)
    No categories
    Direct download  
    Export citation  
    Bookmark   5 citations  
  4.  62
    Predictors of consent to cell line creation and immortalisation in a South African schizophrenia genomics study.Megan M. Campbell, Jantina de Vries, Sibonile G. Mqulwana, Michael M. Mndini, Odwa A. Ntola, Deborah Jonker, Megan Malan, Adele Pretorius, Zukiswa Zingela, Stephanus Van Wyk, Dan J. Stein & Ezra Susser - 2018 - BMC Medical Ethics 19 (1):72.
    Cell line immortalisation is a growing component of African genomics research and biobanking. However, little is known about the factors influencing consent to cell line creation and immortalisation in African research settings. We contribute to addressing this gap by exploring three questions in a sample of Xhosa participants recruited for a South African psychiatric genomics study: First, what proportion of participants consented to cell line storage? Second, what were predictors of this consent? Third, what questions were raised by participants during (...)
    Direct download (6 more)  
    Export citation  
    Bookmark   1 citation  
  5.  25
    Basal ganglia and cortical networks for sequential ordering and rhythm of complex movements.Jeffery G. Bednark, Megan E. J. Campbell & Ross Cunnington - 2015 - Frontiers in Human Neuroscience 9.
  6.  16
    Prioritising African perspectives in psychiatric genomics research: Issues of translation and informed consent.Eunice Kamaara, Camillia Kong & Megan Campbell - 2019 - Developing World Bioethics 20 (3):139-149.
    Psychiatric genomics research with African populations comes with a range of practical challenges around translation of psychiatric genomics research concepts, procedures, and nosology. These challenges raise deep ethical issues particularly around legitimacy of informed consent, a core foundation of research ethics. Through a consideration of the constitutive function of language, the paper problematises like‐for‐like, designative translations which often involve the ‘indigenization’ of English terms or use of metaphors which misrepresent the risks and benefits of research. This paper argues that effective (...)
    Direct download (2 more)  
    Export citation  
  7.  34
    Education versus screening: the use of capacity to consent tools in psychiatric genomics.Camillia Kong, Mehret Efrem & Megan Campbell - 2020 - Journal of Medical Ethics 46 (2):137-143.
    Informed consent procedures for participation in psychiatric genomics research among individuals with mental disorder and intellectual disability can often be unclear, particularly because the underlying ethos guiding consent tools reflects a core ethical tension between safeguarding and inclusion. This tension reflects important debates around the function of consent tools, as well as the contested legitimacy of decision-making capacity thresholds to screen potentially vulnerable participants. Drawing on human rights, person-centred psychiatry and supported decision-making, this paper problematises the use of consent procedures (...)
    Direct download (5 more)  
    Export citation  
  8.  67
    Community engagement strategies for genomic studies in Africa: a review of the literature. [REVIEW]Paulina Tindana, Jantina de Vries, Megan Campbell, Katherine Littler, Janet Seeley, Patricia Marshall, Jennifer Troyer, Morisola Ogundipe, Vincent Pius Alibu, Aminu Yakubu & Michael Parker - 2015 - BMC Medical Ethics 16 (1):24.
    Community engagement has been recognised as an important aspect of the ethical conduct of biomedical research, especially when research is focused on ethnically or culturally distinct populations. While this is a generally accepted tenet of biomedical research, it is unclear what components are necessary for effective community engagement, particularly in the context of genomic research in Africa.
    Direct download (9 more)  
    Export citation  
    Bookmark   19 citations