With the growth of precision medicine research on health data and biospecimens, research institutions will need to build and maintain long-term, trusting relationships with patient-participants. While trust is important for all research relationships, the longitudinal nature of precision medicine research raises particular challenges for facilitating trust when the specifics of future studies are unknown. Based on focus groups with racially and ethnically diverse patients, we describe several factors that influence patient trust and potential institutional approaches to building trustworthiness. Drawing on (...) these findings, we suggest several considerations for research institutions seeking to cultivate long-term, trusting relationships with patients: Address the role of history and experience on trust, engage concerns about potential group harm, address cultural values and communication barriers, and integrate patient values and expectations into oversight and governance structures. (shrink)
Is it time to take a break from feminism? In this pathbreaking book, Janet Halley reassesses the place of feminism in the law and politics of sexuality. She argues that sexuality involves deeply contested and clashing realities and interests, and that feminism helps us understand only some of them. To see crucial dimensions of sexuality that feminism does not reveal--the interests of gays and lesbians to be sure, but also those of men, and of constituencies and values beyond the (...) realm of sex and gender--we might need to take a break from feminism. Halley also invites feminism to abandon its uncritical relationship to its own power. Feminists are, in many areas of social and political life, partners in governance. To govern responsibly, even on behalf of women, Halley urges, feminists should try taking a break from their own presuppositions. Halley offers a genealogy of various feminisms and of gay, queer, and trans theories as they split from each other in the United States during the 1980s and 1990s. All these incommensurate theories, she argues, enrich thinking on the left not despite their break from each other but because of it. She concludes by examining legal cases to show how taking a break from feminism can change your very perceptions of what's at stake in a decision and liberate you to decide it anew. (shrink)
The viability of Schelling’s Philosophy of Identity depends on the maintenance and cultivation of a reciprocal relationship between internal and objective reality. To stay on course Schelling assiduously checked the conceptual answers he derived from subjective thought against the objective measurements of contemporary physics. As the physicists of his day came to question the materiality of light, Schelling conceptualized it as the outer limit of what the intelligence is capable of grasping intuitively. At the same time he criticized Hegel for (...) ignoring knowledge altogether and for propagating a philosophy of ignorance. More than a century later Jacques Derrida recognized this characteristic in Hegel, but drew a contrary conclusion. Where Schelling counseled that rational philosophy should alter course and set sail toward a higher empiricism, Derrida insisted that in pushing rationality beyond its limits Hegel had sprung a trap of incomprehension andindeterminacy from which no one would or could henceforward escape.This essay evaluates the competing claims of Schelling and Derrida in light of the revolutionary advances of twentieth-century physics. Is this work indeed bringing forth a new world the mind qua mind cannot conceive or measure and liberating man from a prior constraint, or are the emerging physical directives of four dimensional space-time and a flat universe themselves possible only within the cloture de la representation where Derrida presumes to detain human kind indefinitely? (shrink)
During the long eighteenth century, boundaries between theology and natural philosophy, between imaginary and factual travel narratives, between fiction and social commentary, were far more fluid than they are today. To explore these relationships, this paper links Mary Shelley’s Frankenstein—a book often hailed as the first science fiction novel—to two earlier works which are now less well known: Edmond Halley’s article about terrestrial magnetism, in which he suggested that God had created inhabited illuminated cavities inside the earth; and a (...) satirical fantasy voyage written by the Danish author Ludvig Holberg, but published anonymously as Niels Klim’s journey to the underground and immediately translated into many languages. Attention is focussed on how the ambiguous presentation of these and other texts blurs any straightforward classification of genres. The aim of examining these writers together is not to search for direct mappings from one project to another, but instead to introduce Holberg’s unfamiliar yet important book and also to cast new light on Frankenstein, one of England’s most famous works of literature.Keywords: Edmond halley; Ludvig holberg; Frankenstein; Plurality of worlds; Science fiction; Magnetism. (shrink)
It is here argued that Halley's comet had a more pivotal role than has hitherto been believed in triggering Newton's acceptance of the law of gravity, dispelling his belief in Descartes' theory of vortices. It is found that historians have been unduly prone to credit Newton with dynamical insights at an earlier date than is warranted by the historical documents. A more convincing account of the transition from the period of Newton's alchemical researches of the 1670s to that of (...) his dynamical insights in the 1680s thereby becomes feasible. Acceptance of a principle of rectilinear inertia was a precondition for formulating the law. (shrink)
A partir de la manipulación mediática propiciada por la dictadura chilena durante los meses previos al avistamiento del cometa Halley en 1986, este artículo lee la ironía presente en el poemario ¡Arre! Halley ¡Arre!, de Elvira Hernández, como una estrategia que, por un lado, pretende confirmar a una comunidad fracturada y que, por otro, critica la pretensión dictatorial de asimilar mesiánicamente el éxito de las incipientes políticas neoliberales con avistamientos astronómicos que se anunciaban como “únicos e irrepetibles”. From (...) the media manipulation prompted by the Chilean dictatorship during the months prior to the sighting of Halley's comet, this article reads the irony present in the poetry collection of Elvira Hernández’s!Arre! Halley! Arre! as a strategy that aims at not only confirming the identity of a fractured community, but also at criticizing the dictatorial intention to assimilate the success of emerging neoliberal policies with “unique and unrepeatable” astronomical sightings. (shrink)
During the eighty years since the publication of the Principia, Newton's theories had been popularized. Based upon them, the first predicted return of any comet aroused anticipation and then elation. Contemporary accounts in widely-read periodicals show the interest in the vindication of gravitational theory provided by fulfilment of the prediction.