Although Aranyosi's claim that McTaggart's "set of parts" is a set rather than a fusion is correct, his attempt to restate McTaggart's conception needs revision. Aranyosi argues that "the fusion of cats is identical with the fusion of all cat-parts, 'regardless of whether all cat-parts are parts of cats or not.'" Fusions have unique decompositions into what David Lewis calls "nice parts." Cats are nice parts of cat fusions, as are maximal spatio-temporally connected parts. Part of Aranyosi's (...) argument fails when it deals with cats; part of it fails when it deals with maximal spatio-temporally connected parts. He does not identify one kind of nice part that allows his whole argument to go through. (shrink)

Contributed articles on the representation of death in different religion, with reference to Indic and European philosophy; includes articles on the representation of death in literature.

The purpose of this study is to offer a brief biography of Mr. M.H. Panhwar and Dr. Nabi Bux Khan Baloch, as well as their work in Sindhological studies along with a brief description of their literary differences on the origin of Sindhi language and history. A systematic literature review methodology was used to explore the contribution and contradiction of both the scholars. The study found that both the scholars were renowned researchers who worked in the fields of history, archaeology, (...) sociology, literature, and language. Both were up-to-dated academics, but their scholarly interests in history, archaeology, language, and literature were diametrically opposed. The study revealed that M.H. Panhwar was a rigorous researcher who conducted studies using scientific techniques and with the assistance of archaeological and geographical evidence. The study further explored that Dr. N. A. Baloch was a folklorist, educationist and extensive writer whose ideological hypotheses were primarily based on mythology and preserved folk literature. (shrink)

Early Tantric Vaiṣṇavism: Three Newly Discovered Works of the Pañcarātra, the Svāyambhuvapañcarātra, Devāmṛtapañcarātra and Aṣṭādaśavidhāna, Critically Edited from Their 11th and 12th Century Nepalese Palm Leaf Manuscripts. Edited with an introduction and notes by Diwakar Acharya. Collection Indologie, vol. 129, Early Tantra Series, vol. 2. Pondichéry and Hamburg: Institut Français de Pondichéry, École Française d’Extrême-Orient, Asien-Afrika-Institut, Universität Hamburg, 2015. Pp. lxxxvi + 229. Rs. 700, €30.

The relationship between brain activity and conscious visual experience is central to our understanding of the neural mechanisms underlying perception. Binocular rivalry, where monocular stimuli compete for perceptual dominance, has been previously used to dissociate the constant stimulus from the varying percept. We report here fMRI results from humans experiencing binocular rivalry under a dichoptic stimulation paradigm that consisted of two drifting random dot patterns with different motion coherence. Each pattern had also a different color, which both enhanced rivalry and (...) was used for reporting which of the two patterns was visible at each time. As the perception of the subjects alternated between coherent motion and motion noise, we examined the effect that these alternations had on the strength of the MR signal throughout the brain. Our results demonstrate that motion perception is able to modulate the activity of several of the visual areas which are known to be involved in motion processing. More specifically, in addition to area V5 which showed the strongest modulation, a higher activity during the perception of motion than during the perception of noise was also clearly observed in areas V3A and LOC, and less so in area V3. In previous studies, these areas had been selectively activated by motion stimuli but whether their activity reflects motion perception or not remained unclear; here we show that they are involved in motion perception as well. The present findings therefore suggest a lack of a clear distinction between ?processing? versus ?perceptual? areas in the brain, but rather that the areas involved in the processing of a specific visual attribute are also part of the neuronal network that is collectively responsible for its perceptual representation. (shrink)

Why mediation? -- What makes bioethics mediation unique? -- Before you begin a bioethics mediation program -- The stages of bioethics mediation -- Techniques for mediating bioethics disputes -- How to write a bioethics mediation chart note -- Mediation with a competent patient : Mr. Samuels's case -- Mediation with a dysfunctional family : Mrs. Bates's case -- A complex mediation with a large and involved family : Mrs. Leonari's case -- Discharge planning for a dying patient : a role-play (...) -- An at-risk pregnancy : a role-play -- HIV and postsurgical complications in the ICU : a role-play -- Treating the dying adolescent : a role-play -- She didn't mean it : a role-play -- Don't tell mama : a role-play -- An at-risk pregnancy : a role-play transcript -- HIV and postsurgical complications in the ICU : a role-play transcript -- She didn't mean it: a role-play transcript -- Don't tell mama : a role-play transcript. (shrink)

Gluten ataxia is a rare immune-mediated neurological disorder caused by the ingestion of gluten. The diagnosis is not straightforward as antibodies are present in only up to 38% of patients, but often at lower titers. The symptoms of ataxia may be mild at the onset but lead to permanent damage if remain untreated. It is characterized by damage to the cerebellum however, the pathophysiology of the disease is not clearly understood. The present study investigated the neurochemical profile of vermis and (...) right cerebellum and structural changes in various brain regions of patients with gluten ataxia and compared it with healthy controls. Volumetric 3-D T1 and T1-weighted magnetic resonance imaging in the three planes of the whole brain and single-voxel 1H- magnetic resonance spectroscopy of the vermis and right cerebellum were acquired on 3 T human MR scanner. The metabolite concentrations were estimated using LC Model while brain volumes were estimated using the online tool volBrain pipeline and CERES and corrected for partial volumes. The levels of neuro-metabolites were found to be significantly lower in vermis, while N-acetyl aspartate + N-acetyl aspartate glutamate and glycerophosphocholine + phosphocholine was lower in cerebellum regions in the patients with gluten ataxia compared to healthy controls. A significant reduction in the white matter of ; reduction in the volumes of cerebellum lobe and thalamus while lateral ventricles were increased in the patients with gluten ataxia compared to healthy controls. The reduced neuronal metabolites along with structural changes in the brain suggested neuronal degeneration in the patients with gluten ataxia. Our preliminary findings may be useful in understanding the gluten-induced cerebral damage and indicated that MRI and MRS may serve as a non-invasive useful tool in the early diagnosis, thereby enabling better management of these patients. (shrink)

Mr. G. B. KERFERD, in C.Q. xlviii , 84 ff. writes of ‘Plato's Noble Art of Sophistry’. He suggests that Plato thought there was a ‘Noble Art’ of sophistry, other than philosophy itself; and he seeks to find this Art in the better and worse arguments of Protagoras. This suggestion is, unfortunately, based on a mistranslation of Plato, Sophist 231 a:.

Mr. Bartley's remark that Goodman's puzzle is “an interesting variant of the possibility... that the next instance may be different” rather badly misrepresents matters. One might say that the “new riddle” arises just because no matter what the nature of the next instance, it will be as much like all previously examined cases as any other instance. Suppose “Hester” is the name of the first emerald examined after time t. If Hester is green, then Hester is like previously examined emeralds (...) with respect to their green-ness. But should Hester be blue, then Hester has its grue-ness in common with previously examined emeralds. The difficulty here is that likenesses abound; the evidence presents us with more likenesses than we could consistently expect of or project to subsequent cases. And the question that Goodman's puzzle poses is, by what criteria do we select one from among all of these likenesses to project to subsequent cases? (shrink)

On the life and teachings of Śaṅkarācārya; includes history of Daivadnya Brahmans, Hindu caste in coastal region of Maharashtra, Goa, Karnataka, and Kerala.

Carbon monoxide intoxication leads to acute and chronic neurological deficits, but little is known about the specific noxious mechanisms. 1 H magnetic resonance spectroscopy may allow insight into the pathophysiology of CO poisoning by monitoring neurochemical disturbances, yet only limited information is available to date on the use of this protocol in determining the neurological effects of CO poisoning. To further examine the short-term and long-term effects of CO on the central nervous system, we have studied seven patients with CO (...) poisoning assessed by gray and white matter MRS, magnetic resonance imaging and neuropsychological testing. Five patients suffered from acute high-dose CO intoxication and were in coma for 1–6 days. In these patients, MRI revealed hyperintensities of the white matter and globus pallidus and also showed increased choline and decreased N -acetyl aspartate ratios to creatine, predominantly in the white matter. Lactate peaks were detected in two patients during the early phase of high-dose CO poisoning. Two patients with chronic low-dose CO exposure and without loss of consciousness had normal MRI and MRS scans. On follow-up. five of our seven patients had long-lasting intellectual impairment, including one individual with low-dose CO exposure. The MRS results showed persisting biochemical alterations despite the MRI scan showing normalization of morphological changes. In conclusion, the MRS was normal in patients suffering from chronic low-dose CO exposure; in contrast, patients with high-dose exposure showed abnormal gray and white matter levels of NAA/Cr, Cho/Cr and lactate, as detected by 1 H MRS, suggesting disturbances of neuronal function, membrane metabolism and anaerobic energy metabolism, respectively. Early increases in Cho/Cr and decreases of NAA/Cr may be related to a poor long-term outcome, but confirmation by future studies is needed. (shrink)

A variety of studies show that parental absence early in life leads to deleterious effects on the developing CNS. This is thought to be largely because evolutionary-dependent stimuli are necessary for the appropriate postnatal development of the young brain, an effect sometimes termed the “experience-expectant brain,” with parents providing the necessary input for normative synaptic connections to develop and appropriate neuronal survival to occur. Principal among CNS systems affected by parental input are the monoamine systems. In the present study,N= 434 (...) rhesus monkeys (233 males, 201 females) were reared in one of two conditions: as mother-reared controls (MR;n= 269) or without adults with 24-h access to same-aged peers (PR;n= 165). When subjects were six-months-old, they underwent a separation paradigm involving 4, sequential, four-day social separations from their mothers or peers, with each separation followed by three-day reunions with their mothers or their peers. Prior to the separation paradigm, baseline cisternal CSF samples were obtained, as well as at the end of each the four social separations, and after final separation, during a recovery period. CSF was assayed for concentrations of monoamine metabolites and a blood sample was genotyped for the serotonin transporter (5-HTT) genotype. Replicating earlier landmark findings, PR subjects with thesallele exhibited lower baseline concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA), when compared to PR subjects homozygous for theLallele. MR subjects were undifferentiated by genotype. PR subjects exhibited lower CSF 5-HIAA concentrations during baseline, but higher CSF 5-HIAA during social separations, when compared to MR subjects. There were rearing effects for the dopamine metabolite homovanillic acid (HVA) and for the norepinephrine metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG), with PR subjects showing higher HVA and lower MHPG when compared to MR subjects. These findings indicate that there are long-term deficits in the response of monoamines following early maternal absence. The results of this study confirm and extend earlier findings that early parental absence has deleterious consequences for the development of the monoamine systems, and that these consequences are modulated by the 5-HTT genotype. (shrink)

Study on Hinduism; with a special reference to the world religions and science.

The average British fourteen-year-old watches a great deal of TV. He helps to spend a quarter of a million pounds on pop records every Saturday. Like the rest of us he is beset by advertisements. As an adult he is virtually certain to read mass-circulation daily and Sunday newspapers. This is his mental world. The modern teacher wants to bring this world to the classroom but if he merely tries the Old Testament prophet stance and says its all corrupt, he (...) will be written off a hopelessly out of touch. But if he can take a neutral position, he can get his pupils first to discuss, then to understand and finally to discriminate. Mr Tucker's book will help this process. The plan of his book if simple: he takes the mass media one by one, gives first some understanding of their organisation, characteristics, aims and methods and then gives practical suggestions for class-work on them. (shrink)

It was an excellent idea of Mr. Strasser to submit to a detailed analysis the fundamental phenomenon of what in German is called ‘Gemüt’—there is no exact English equivalent—on which little is found in philosophical literature. Without doubt it is one of the fields in psychology which, notwithstanding all that has to date been done in the domain of ‘Tiefenpsychologie’ and other modern trends, is still to a great extent terra incognita.

We are printing, by kind permission of the Law Commission, two sections of the report of the Law Commission on injuries to unborn children. This report was the result of a request to the Law Commission by the Lord Chancellor at the time (Lord Hailsham of Saint Marylebone) to advise on `what the nature and extent of civil liability for antenatal injury should be'. The Law Commission followed its usual practice in such circumstances of consulting various bodies and obtaining expert (...) advice on the subject and then embodying the results in a working paper (Working Paper No. 47 - injuries to unborn children) published on 19 January 1973, which preceded their report (Cmnd 5709). Meanwhile a Royal Commission is considering much wider issues of civil liability for injury (including antenatal injury) but the terms of reference for the Law Commission were much narrower and confined to the position of children injured before birth. In the section relating to the present law the report makes it clear that it is probable that liability under the common law already exists. The Scottish Law Commission has also issued a report (Cmnd 5371). They were given different terms of reference and came to somewhat different conclusions. We are printing from this long report the paragraphs discussing the medical background and the summary of recommendations. As will be evident on reading the paragraphs on the medical background to injuries to the unborn child, events are moving very rapidly, particularly in the study of congenital defects and the effects of drugs but the problems of proof present great difficulty. Other causes of injury to the unborn child are better known to the general public: for example, those following the illness, infection and disease of the mother during pregnancy, injury caused in attempted termination of pregnancy and the risks resulting from the mother's condition. The summary of the recommendations sets out very clearly the legal position of the unborn child, as the Law Commission sees it, arising from injury before birth, the final conclusion being that `legislation is desirable'. These extracts from the report, apart from their intrinsic interest, lead on to the paper by Mr Kennedy and Dr Edwards in which they set out their criticisms of it, and provide quick references to the original document. (shrink)

Background: We were finding volunteers for functional magnetic resonance imaging studies with abnormalities requiring referral surprisingly frequently. The bioethics surrounding the incidental findings are not straightforward and every imaging institution will encounter this situation in their normal volunteers. Yet the implications for the individuals involved may be profound. Should all participants have review of their imaging by an expert and who should be informed? Methods: The normal volunteers that were imaged with magnetic resonance (MR) which were reviewed by a consultant (...) neuroradiologist. All participants completed a volunteer consent form in addition to a standard departmental MR safety screening form. The volunteer screening form requires the general practitioner details to be completed and asks the participant to consider closely the possibility and implications of finding an unexpected but potentially serious abnormality before signing. Results: 525 different individuals were scanned as normal volunteers, the mean age was 35-years and 330 were males. Of these 525, 46 had definite significant abnormalities (8.8%), mean age 50-years. Conclusion: We have found a high rate of incidental abnormalities amongst individuals participating in imaging studies at our institution. It is our current practice to inform the research study participant of the findings, counsel them and inform their primary care physician. We think that it is advisable for researchers utilising MR imaging of the brain to have access to trained neuroradiologists, a protocol in place to deal with this problem and take consent in a way that allows the participant to realise the possibility of an abnormal finding. (shrink)

It was an excellent idea of Mr. Strasser to submit to a detailed analysis the fundamental phenomenon of what in German is called ‘Gemüt’—there is no exact English equivalent—on which little is found in philosophical literature. Without doubt it is one of the fields in psychology which, notwithstanding all that has to date been done in the domain of ‘Tiefenpsychologie’ and other modern trends, is still to a great extent terra incognita.

What was the source of this great flowering? Much of the credit for it has tended to go to Jacobi and Mendelssohn, who in 1785 began a famous public dispute concerning the question whether or not Lessing had been a Spinozist, as Jacobi alleged Lessing had admitted to him shortly before his death in 1781. But Jacobi and Mendelssohn were both negatively disposed towards Spinoza. In On the Doctrine of Spinoza in Letters to Mr.

"Contemporary Mind - Some Modern Answers" is a fantastic collection of essays by English science writer John W. Sullivan. They deal with a range of subjects, ranging from mysticism and immortality to the relationship between science and art. John William Navin Sullivan (1886 - 1937) was a literary journalist and popular science writer most famous for his study of Beethoven. He is also responsible for having written some of the earliest non-technical accounts of Einstein's General Theory of Relativity, and he (...) was acquainted with many important writers in London in the 1920s, including John Middleton Murry, Aldous Huxley, Wyndham Lewis, Aleister Crowley and T. S. Eliot. Other notable works by this author include "Aspects of Science" (1923), "Aspects of Science: Second Series" (1926), and An Outline of Modern Knowledge (1931). Contents include: "The Balanced Life," "The Problem of Suffering," "The Necessity of Mysticism," "Human Immortality," "A Dissertation on Beethoven," "The Scientific Outlook," "A Dissertation on Maxwell," "New Principles," "A Dissertation on Newton," "Science and Art," "Mathematics and Culture," "Sir Josiah Stamp," "Mr. Aldous Huxley," etc. Many vintage books such as this are increasingly scarce and expensive. It is with this in mind that we are republishing this volume now in an affordable, modern, high-quality edition complete with the original text and artwork. (shrink)

This is a brilliant presentation of Museum Thomism, all the more interesting in that the museum is located in Oxford. Mr Kenny knows well the objects he is presenting and knows how to bring a sharp analytical light to bear on them. Under this light they are as full of flaws as a Rembrandt examined under a microscope. The Five Ways lead nowhere, least of all to God.

Commentary on Tarkasaṅgraha of Annambhaṭṭa, active 17th century, treatise on the fundamentals of Nyaya philosophy.

Mental retardation is an invented bureaucratic category, currently undergoing radical rethinking and likely renaming, that includes many who have biologically based brain disorders, but is itself determined on functional criteria that are purely arbitrary. People with MR are socially vulnerable and thus are more likely to be "naíve confessors," "naíve defendants," and "naíve offenders." That is most likely the rationale and justification for the Supreme Court's decision, in Atkins v. Virginia, to exempt the class from execution. Although the decision is (...) to be applauded as a step in a more humane direction, it is problematic to use an indirect, artificial, and insufficiently inclusive category to determine who should or should not be executed. Limited social intelligence is a characteristic of a wide range of brainbased syndromes and disorders, including many who fall above the upper IQ limit and, thus, are ineligible for the MR label and the legal protections associated with it. A more equitable, and logical, policy would be to extend execution exemption to all who demonstrate the same kinds of vulnerabilities, especially if they can be linked to some brain-based medical condition, regardless of whether one qualifies for the label of MR. (shrink)

This paper provides an evolutionary rationale for both interracial and intraracial wage differentials by examining the implications of white employers mediating their employer?employee relationships on the basis of genetic similarity. If in organized labor markets; relationships mediated through genetic similarity are optimal in terms of Darwinian fitness, a fundamental evolutionary implication is that the Marginal Rate of Substitution (MRS) in Darwinian fitness holding extended fitness constant equals the MRS in preferences holding utility constant. Given such an evolutionary equilibrium, results are (...) derived showing that the strength of tastes for discrimination depends upon the skin hue of non?white workers. The rationale established for racial wage differentials is that where skin hue serves to indicate genetic similarity between employer and employee, wage differentials emerge that are a function of skin hue. (shrink)

Particular attention has been paid in the present century to the question as to whether a man's duty is to do what is actually right, i.e. what his situation actually demands of him, or what he thinks is right. Mr. Carritt has pointed out that the former possibility bifurcates—a man's duty may be to do what is actually demanded by his actual situation, or what is actually demanded by what he believes to be his situation. I do not propose in (...) the present paper to carry this discussion any further, but rather to consider how it has been carried on in the past, as there seems to be a little confusion on this point. (shrink)

In 1919 Emily James Putnam gave twelve lectures at the New School under the title of “Habit and History.” The course description is as follows:The long predominance of habitual conduct over individual initiative in primitive society and in the early empires; the biological and social limitations which tend to foster habit and develop it beyond its proper sphere; the technique of habitbreaking inaugurated by the Greeks and becoming a characteristic of western society; an effort to appraise the amount of excessive (...) and undesirable habit in thought and action generally connected with such concepts as nationalism, religion, the status of women, etc.It is an interesting challenge, eighty-two years later, to try to understand what Mrs. James meant by that description and how to think about those issues today. Mrs. James contrasts the term `habitual conduct' to the term `individual initiative,' and finds the former more characteristic of primitive society and the early empires whereas the latter, beginning with the habit-breaking Greeks, is more characteristic of Western society. She does not reject habit altogether, indicating that it has a `proper sphere,' but only `excessive and undesirable habit,' and she suggests that nationalism, religion and the status of women are spheres where such excessive and undesirable habits are to be found.Without being able to peruse her lectures in detail, I cannot be sure of all that she is implying. One might note that in her contrast between habit and individual initiative she privileges, as until recently we have been wont to do, the West as against the rest. This contrast, with its whiff of Orientalism, might serve to warn us that, although the contrast at the heart of her lecture series is still part of our common sense today, it, like the contrast between the West and the non-West, ought not be affirmed until subjected to a degree of critical suspicion. (shrink)