BackgroundInnovations in technology have contributed to rapid changes in the way that modern biomedical research is carried out. Researchers are increasingly required to endorse adaptive and flexible approaches to accommodate these innovations and comply with ethical, legal and regulatory requirements. This paper explores how Dynamic Consent may provide solutions to address challenges encountered when researchers invite individuals to participate in research and follow them up over time in a continuously changing environment.MethodsAn interdisciplinary workshop jointly organised by the University of Oxford (...) and the COST Action CHIP ME gathered clinicians, researchers, ethicists, lawyers, research participants and patient representatives to discuss experiences of using Dynamic Consent, and how such use may facilitate the conduct of specific research tasks. The data collected during the workshop were analysed using a content analysis approach.ResultsDynamic Consent can provide practical, sustainable and future-proof solutions to challenges related to participant recruitment, the attainment of informed consent, participant retention and consent management, and may bring economic efficiencies.ConclusionsDynamic Consent offers opportunities for ongoing communication between researchers and research participants that can positively impact research. Dynamic Consent supports inter-sector, cross-border approaches and large scale data-sharing. Whilst it is relatively easy to set up and maintain, its implementation will require that researchers re-consider their relationship with research participants and adopt new procedures. (shrink)

Features new to the second edition include a foreword by Tynnetta Muhammad, wife and student of Elijah Muhammad; opening comments by world renowned mathematician Dr. Abdulalim Sahabazz; a new chapter co-authored with Dr. Dorothy Blake Fardan; plus guided questions and power point notes to stimulate discourse around Elijah Muhammad's educational ideas.

'O men, serve your Lord who created you and those before you, so that you may guard against evil. Deals with Allah, Prophet Muhammad PBUH, Hazrat Mirza Ghulam Ahmad Sahib -- What are the signs of the appearance of the promised messiah? and do these signs appear in the being of Hazrat Mirza Sahib?

Machiavellians are manipulative and deceitful individuals willing to utilize any strategy or behavior needed to attain their goals. This study explores what occurs when Machiavellian employees have a Machiavellian leader with the same negative, manipulative disposition. We argue that Machiavellian employees have a negative worldview and are likely to trust their leaders less. This reduced trust likely results in these employees experiencing higher stress and engaging in more unethical behavior. In addition, we expect these negative relationships to be exacerbated when (...) such followers experience Machiavellian leadership. Thus, we test a moderated mediation model assessing whether Machiavellianism affects employees and whether combining Machiavellian leaders and Machiavellian employees is toxic in the sense of exacerbating the negative impact of Machiavellianism on employee trust. Results do not support the proposed conditional indirect effect of trust for either stress or unethical behavior. Instead, we find a conditional direct effect of employee Machiavellianism on both trust and stress: When Machiavellian employees have Machiavellian leaders, their trust in their leader significantly decreases, and their level of stress significantly increases. We also find support for an unconditional indirect effect of trust for employee stress, Machiavellianism in employees relates to stress via lowered trust in the leader. For unethical behavior, we only find a main effect of employee Machiavellianism. (shrink)

Machiavellians are manipulative and deceitful individuals willing to utilize any strategy or behavior needed to attain their goals. This study explores what occurs when Machiavellian employees have a Machiavellian leader with the same negative, manipulative disposition. We argue that Machiavellian employees have a negative worldview and are likely to trust their leaders less. This reduced trust likely results in these employees experiencing higher stress and engaging in more unethical behavior. In addition, we expect these negative relationships to be exacerbated when (...) such followers experience Machiavellian leadership. Thus, we test a moderated mediation model assessing whether Machiavellianism affects employees and whether combining Machiavellian leaders and Machiavellian employees is toxic in the sense of exacerbating the negative impact of Machiavellianism on employee trust. Results do not support the proposed conditional indirect effect of trust for either stress or unethical behavior. Instead, we find a conditional direct effect of employee Machiavellianism on both trust and stress: When Machiavellian employees have Machiavellian leaders, their trust in their leader significantly decreases, and their level of stress significantly increases. We also find support for an unconditional indirect effect of trust for employee stress, Machiavellianism in employees relates to stress via lowered trust in the leader. For unethical behavior, we only find a main effect of employee Machiavellianism. (shrink)

Oriental scholars discuss the concept of corporate personalitywithout any reference to Islamic law. A leading proponent of this view isJoseph Schacht; a western scholar of jurisprudence who contended that Islamicjurisprudence is limited to individual personality and devoid of corporate laws,hence, contractual agreements between corporations has no basis in Islamiclaw. Several scholars and researcher have responded with sufficient literatureon the status of an artificial person in Islamic law, but there are still issues withthe legal implication of corporate personality in the event (...) of financial distress.This study aims to explore Islamic threshold on fundamental principles ofcorporate personalities and its contemporary applications in the situation offinancial trouble. The study will employ the analytical approach in describingthe essential characteristics of a corporation as inherent in Islamic law throughinterpolation from the natural person and the possibility of adapting the existingconventional bankruptcy laws. This study employs an analytical approach to Islamic literature and regular related works. The study found out that eventhough the concept of financial distress has basis in Islamic law, it remainscomplicated as it entails insolvency, bankruptcy and interdiction in a debtorcreditorrelationship. Overall, further efforts need to be done to put theseconcepts into contemporary and applicable perspectives without violatingIslamic fundamental principle of justice and fair dealings. (shrink)

In jails, the prisoners are often maltreated by the jail authorities.They are abused, and, their fundamental rights as human beings are frequentlyviolated. Although laws upholding the rights of prisoners are plenty,unfortunately, these seem ineffective in preventing the abuse of prisonersin jails. This paper examines the problems of jailed prisoners in general andhighlights their violations of human rights. In particular, this paper discussessexual abuse of prisoners, their mental and physical tortures, and enforcement ofprison labour laws. The paper also focuses on overcrowding (...) in jails, inadequateeducational facilities for prisoners and poor health care facilities. This articleanalyses these issues from the perspectives of Islamic Law and attempts toprovide a conceptual frame work of solutions. An analytical approach isemployed in this study. (shrink)

Contemporary research, across various disciplines, alludes to notion of complexity. Indeed, the phenomenon has even been accredited for comprising a new “world-view” that not only heralds theory construction but also instigates miscellaneous nifty yet practical avenues. On the other hand, however, the complexityparadigm has frequently been criticized of obscurity, contestation and scope imprecision. In addition, its various mutually incommensurable philosophical implications have lead to much heated debates regarding methodological pluralism and metaphorical applications, within literature. To elaborately discussand resolve these concerns, (...) this paper will be organized in three sections: The first section will build on the idiosyncratic characteristics of complexity that differentiate it from related notions of chaos and complicatedness. The second section will shed light on the philosophical deliberations of individual complexityattributes, toward metaphysics of complexity, through elaborately drawn diagrams. Also, this section will draw attention to several conflicting perspectives encompassing the theological, epistemological and ontological domain of complexity. The third section will trace the origins of such paradoxical debates, in the complexity literature, through a ‘Super-System-Outlook’ (SSO) framework. The framework is likely to be of particular significance as it aims to not only divulge an eradicable joint cause of the disparity governing complexity studies but also to propose a possible assimilation of such deliberations. (shrink)

An embedded automaton is introduced to monitor the whole glycolysis process in pancreatic β-cell and it is a hybridization of both non-deterministic finite automaton and push-down automaton. The set of irreversible and reversible reactions in the glycolysis process are related to non-deterministic finite automaton and push-down automaton respectively. The embedded automaton is used to observe the glucose metabolism with the states of acceptance and rejection. The acceptance state of the embedded automaton depicts the normal level of glycolysis and insulin secretion. (...) The rejection state of this machine shows inhibition of glycolysis which obstructs the secretion of insulin. The subsequent low level of insulin leads to the high blood glucose level also known as hyperglycemia. In this study, the designed machine can be used to regulate the process of glycolysis through a group of regulatory glycolytic enzymes for the treatment of Diabetes mellitus at molecular level. (shrink)

Research generally concludes that small businesses contribute to economic development. In Malaysia, small firm’s particularly Chinese small firms have played a very important role for economic growth in this country. Chinese firms have managed to survive, grow and succeed either in Malaysia or anywhere else in the world. Most prior research found that the success factor was related to their socio-cultural context. However, previous studies have found the similarities on the cultural values of the Malays and Chinese which derived from (...) ‘Budi Complex’ and ‘Confucianism’ respectively. It was particularly on certain selected values related to self, time and epistemology. Therefore, this paper tries to identify other reasons behind the success factor of the Chinese as compared to the Malay small firms. Thus, looking at the perspective of Knowledge Base View theory, this paper proposed that cultural values are not a mere factor that affect the way Chinese small firms market their operation. The current study thus proposed that how Chinese and Malays acquire and share knowledge, have significant contribution to their success or their failures. (shrink)

INTRODUCTION The most remarkable feature of the character of the Persian people is their love of Metaphysical speculation. Yet the inquirer who approaches the extant literature of Persia expecting to find any comprehensive systems of thought, like those of Kapila or Kant, will have to turn back disappointed, though deeply impressed by the wonderful intellectual subtlety displayed therein. It seems to me that the Persian mind is rather impatient of detail, and consequently destitute of that organising faculty which gradually works (...) out a system of ideas, by interpreting the fundamental principles with reference to the ordinary facts of observation. The subtle Brahman sees the inner unity of things; so does the Persian. But while the former endeavours to discover it in all the aspects of human experience, and illustrates its hidden presence in the concrete in various ways, the latter appears to be satisfied with a bare universality, and does not attempt to verify the richness of its inner content. The butterfly imagination of the Persian, flies half-inebriated as it were, from flower to flower, and seems to be incapable of reviewing the garden as a whole. For this reason, his deepest thoughts and emotions find expression mostly in disconnected verses (Ghazal), which reveal all the subtlety of his artistic soul. The Hindu, while admitting, like the Persian, the necessity of a higher source of knowledge, yet calmly moves from experience to experience, mercilessly dissecting them, and forcing them to yield their underlying universality. In fact the Persian is only half-conscious of Metaphysics as a system of thought; his Brahman brother, on the other hand, is fully alive to the need of presenting his theory in the form of a thoroughly reasoned out system. And the result of this mental difference between the two nations is clear. In the one case we have only partially worked out systems of thought; in the other case, the awful sublimity of the searching Vedanta ... (shrink)

This paper discusses inheritance discourse based on verses of the Qur’an according to modern interpreters, Muḥammad Shaḥrūr with Munawir Sjadzali. Both interpreters are appointed because they can be considered to have tried in their respective contexts to answer the emergence of ambiguous attitudes in implementing inheritance law from Muslim societies. Muḥammad Shaḥrūr understands and applies it in a way that is different from the opinions and concepts, as seen in the 'four classical patterns of calculation' as well as in social (...) aspects, such as the concept of patrilinialism in society and the spirit of kinship and family spirit and ethnicity which became the benchmark for the distribution of inheritance in the past century or in political aspects, such as overlapping concepts of inheritance law which confuse ownership, law and prophetic authority. From this there is a clear relevance between the boundary theory proposed by Shaḥrūr and the efforts to reform Islamic law which are expected to grow with justice and be able to answer the needs of the community. Whereas Sjadzali developed the concept of inheritance contained in the Qur'an, to look for the relevance of Islamic teachings to the times, especially in the context of Modern Indonesia. Since al-Qur'an is multidimensional, as hudan li al-nās, the concept of Sjadzali's inheritance law has its own value, namely by teaching the principle of equality as the division of men is twice as large as women is no longer relevant. He also did not explain the division of inheritors who have an upward line adequately. This is because Sjadzali only sees from the side of the historicity of the region as the birth of his 1: 1 inheritance concept, without regard to other aspects such as heirs and heirs. (shrink)

This paper discusses inheritance discourse based on verses of the Koran according to modern interpreters, Muḥammad Shaḥrūr with Munawir Sjadzali. Both interpreters are appointed because they can be considered to have tried in their respective contexts to answer the emergence of ambiguous attitudes in implementing inheritance law from Muslim societies. Muḥammad Shaḥrūr understands and applies it in a way that is different from the opinions and concepts, as seen in the 'four classical patterns of calculation' as well as in social (...) aspects, such as the concept of patrilinialism in society and the spirit of kinship and family spirit and ethnicity which became the benchmark for the distribution of inheritance in the past century or in political aspects, such as overlapping concepts of inheritance law which confuse ownership, law and prophetic authority. From this there is a clear relevance between the boundary theory proposed by Shaḥrūr and the efforts to reform Islamic law which are expected to grow with justice and be able to answer the needs of the community. Whereas Sjadzali developed the concept of inheritance contained in the Qur'an, to look for the relevance of Islamic teachings to the times, especially in the context of Modern Indonesia. Since al-Qur'an is multidimensional, as hudan li al-nās, the concept of Sjadzali's inheritance law has its own value, namely by teaching the principle of equality as the division of men is twice as large as women is no longer relevant. He also did not explain the division of inheritors who have an upward line adequately. This is because Sjadzali only sees from the side of the historicity of the region as the birth of his 1: 1 inheritance concept, without regard to other aspects such as heirs and heirs. (shrink)

Name der Zeitschrift: Der Islam Jahrgang: 94 Heft: 2 Seiten: 363-384.

A comparison between Muḥammad and Siddhārtha’s psychological states is made to identify how they had their mystical experiences and how their presuppositions and personalities shaped their interpretation of these experiences. Muḥammad’s mystical experience appeared to be based on an altered state of consciousness. Siddhārtha’s teachings include that one must not have blind faith and remain open to various truths. These teachings may reflect that he was high in openness to experience, which may have fortified him from becoming delusional. While mystical (...) experiences may have pathological overlaps, they could be categorized in a similar way to psychological states. Yet, mindful presuppositions and personality traits, especially from within openness to experience spectrum, are what make perceptions of these experiences diverse. (shrink)