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  1.  94
    The Social Value of Health Research and the Worst Off.Nicola Barsdorf & Joseph Millum - 2017 - Bioethics 31 (2):105-115.
    In this article we argue that the social value of health research should be conceptualized as a function of both the expected benefits of the research and the priority that the beneficiaries deserve. People deserve greater priority the worse off they are. This conception of social value can be applied for at least two important purposes: in health research priority setting when research funders, policy-makers, or researchers decide between alternative research projects; and in evaluating the ethics of proposed research proposals (...)
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  2.  35
    Stakeholder Perspectives on Ethical Challenges in Hiv Vaccine Trials in South Africa.Zaynab Essack, Jennifer Koen, Nicola Barsdorf, Catherine Slack, Michael Quayle, Cecilia Milford, Graham Lindegger, Chitra Ranchod & Richard Mukuka - 2010 - Developing World Bioethics 10 (1):11-21.
    There is little published literature on the ethical concerns of stakeholders in HIV vaccine trials. This study explored the ethical challenges identified by various stakeholders, through an open-ended, in-depth approach. While the few previous studies have been largely quantitative, respondents in this study had the opportunity to spontaneously identify the issues that they perceived to be of priority concern in the South African context. Stakeholders spontaneously identified the following as ethical priorities: informed consent, social harms, collaborative relationships between research stakeholders, (...)
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  3.  12
    Access to Treatment in Hiv Prevention Trials: Perspectives From a South African Community.Nicola Barsdorf, Suzanne Maman, Nancy Kass & Catherine Slack - 2010 - Developing World Bioethics 10 (2):78-87.
    Access to treatment, in HIV vaccine trials (HVTs), remains ethically controversial. In most prevention trials, including in South Africa, participants who seroconvert are referred to publicly funded programmes for treatment. This strategy is problematic when there is inadequate and uneven access to public sector antiretroviral therapy (ART) and support resources. The responsibilities, if any, of researchers, sponsors and public health authorities involved in HVTs has been hotly debated among academics, scholars, representatives of international organizations and sponsors. However, there is little (...)
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  4.  14
    Exploring the Ethics of Global Health Research Priority-Setting.Bridget Pratt, Mark Sheehan, Nicola Barsdorf & Adnan A. Hyder - 2018 - BMC Medical Ethics 19 (1):94.
    Thus far, little work in bioethics has specifically focused on global health research priority-setting. Yet features of global health research priority-setting raise ethical considerations and concerns related to health justice. For example, such processes are often exclusively disease-driven, meaning they rely heavily on burden of disease considerations. They, therefore, tend to undervalue non-biomedical research topics, which have been identified as essential to helping reduce health disparities. In recognition of these ethical concerns and the limited scholarship and dialogue addressing them, we (...)
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