Advancements in novel neurotechnologies, such as brain computer interfaces and neuromodulatory devices such as deep brain stimulators, will have profound implications for society and human rights. While these technologies are improving the diagnosis and treatment of mental and neurological diseases, they can also alter individual agency and estrange those using neurotechnologies from their sense of self, challenging basic notions of what it means to be human. As an international coalition of interdisciplinary scholars and practitioners, we examine these challenges and make (...) recommendations to mitigate negative consequences that could arise from the unregulated development or application of novel neurotechnologies. We explore potential ethical challenges in four key areas: identity and agency, privacy, bias, and enhancement. To address them, we propose democratic and inclusive summits to establish globally-coordinated ethical and societal guidelines for neurotechnology development and application, new measures, including “Neurorights,” for data privacy, security, and consent to empower neurotechnology users’ control over their data, new methods of identifying and preventing bias, and the adoption of public guidelines for safe and equitable distribution of neurotechnological devices. (shrink)

Japanese English learners have difficulty speaking Double Object than Prepositional Object structures which neural underpinning is unknown. In speaking, syntactic and phonological processing follow semantic encoding, conversion of non-verbal mental representation into a structure suitable for expression. To test whether DO difficulty lies in linguistic or prelinguistic process, we conducted functional magnetic resonance imaging. Thirty participants described cartoons using DO or PO, or simply named them. Greater reaction times and error rates indicated DO difficulty. DO compared with PO showed parieto-frontal (...) activation including left inferior frontal gyrus, reflecting linguistic process. Psychological priming in PO produced immediately after DO and vice versa compared to after control, indicated shared process between PO and DO. Cross-structural neural repetition suppression was observed in occipito-parietal regions, overlapping the linguistic system in pre-SMA. Thus DO and PO share prelinguistic process, whereas linguistic process imposes overload in DO. (shrink)

Illusory kinesthetic sensation was influenced by motor imagery of the wrist following tendon vibration. The imagery and the illusion conditions commonly activated the contralateral cingulate motor area, supplementary motor area, dorsal premotor cortex, and ipsilateral cerebellum. This supports the notion that motor imagery is a mental rehearsal of movement, during which expected kinesthetic sensation is emulated by recruiting multiple motor areas, commonly activated by pure kinesthesia.

There is a task-specificity in the visual-tactile interaction for perception: The polymodal posterior parietal cortex is related to the comparison of the shapes coded by different sensory modalities, whereas the lateral occipital complex is the part of the network for multimodal shape identification. These interactions may be mediated by some latent pathways potentiated by sensory deprivation or learning.