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Pierre Baconnier [3]P. Baconnier [3]Pierre F. Baconnier [1]
  1.  21
    Positive End Expiratory Pressure and Expiratory Flow Limitation: A Model Study.S. Khirani, L. Biot, A. Eberhard & P. Baconnier - 2001 - Acta Biotheoretica 49 (4):277-290.
    Patients suffering from chronic obstructive pulmonary diseases, frequently exhibit expiratory airflow limitation. We propose a mathematical model describing the mechanical behavior of the ventilated respiratory system. This model has to simulate applied positive end-expiratory pressure effects during expiration, a process used by clinicians to improve airflow. The proposed model consists of a nonlinear two-compartment system. One of the compartments represents the collapsible airways and mimics its dynamic compression, the other represents the lung and chest wall compartment. For all clinical conditions (...)
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  2.  12
    Ventilatory Support: A Dynamical Systems Approach.Sylvain Thibault, Laurent Heyer, Gila Benchetrit & Pierre Baconnier - 2002 - Acta Biotheoretica 50 (4):269-279.
    Misunderstanding of the dynamical behavior of the ventilatory system, especially under assisted ventilation, may explain the problems encountered in ventilatory support monitoring. Proportional assist ventilation (PAV) that theoretically gives a breath by breath assistance presents instability with high levels of assistance. We have constructed a mathematical model of interactions between three objects: the central respiratory pattern generator modelled by a modified Van der Pol oscillator, the mechanical respiratory system which is the passive part of the system and a controlled ventilator (...)
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  3.  19
    Preface.Pierre Baconnier & Jacques Viret - 1999 - Acta Biotheoretica 47 (3-4):171-172.
  4.  13
    Simulation of Pulmonay Damages Induced by Inhaled CL2 on the Bronchial Tree.Pierre F. Baconnier, Catherine Marey & Ahmed Ménaouar - 1997 - Acta Biotheoretica 45 (3-4):237-250.
    We have measured the change of lung mechanical parameters on isolated rabbit lungs exposed to chlorine gas (Cl{in2}). Experimental results show parallel increase in elastance and resistance of impaired lungs. We tried to determine whether this may be explained by a reduction of the ventilated areas in the lung, consecutive to closure of some airways. We have then tried to simulate these experimental results by studying the effects of various airways occlusions imposed on two concurrent models (symmetrical and dissymmetrical) of (...)
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  5.  13
    Identification of a Non-Linear Model as a New Method to Detect Expiratory Airflow Limitation in Mechanically Ventilated Patients.S. Khirani, L. Biot, P. Lavagne, A. Duguet, T. Similowski & P. Baconnier - 2004 - Acta Biotheoretica 52 (4):241-254.
    Expiratory flow limitation (EFL) can occur in mechanically ventilated patients with chronic obstructive pulmonary disease and other disorders. It leads to dynamic hyperinflation with ensuing deleterious consequences. Detecting EFL is thus clinically relevant. Easily applicable methods however lack this detection being routinely made in intensive care. Using a simple mathematical model, we propose a new method to detect EFL that does not require any intervention or modification of the ongoing therapeutic. The model consists in a monoalveolar representation of the respiratory (...)
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