Autism is a group of complex neurodevelopmental disorders characterized by impaired social interaction and restricted/repetitive behavior. We performed a large-scale retrospective analysis of 1,996 clinical neurological structural magnetic resonance imaging (MRI) examinations of 781 autistic and 988 control subjects (aged 0 to 32 years), and extracted regionally distributed cortical thickness measurements, including average measurements as well as standard deviations which supports the assessment of intra-regional cortical thickness variability. The youngest autistic participants (< 2.5 years) were diagnosed after imaging and were (...) identified retrospectively. The largest effect sizes and the most common findings not previously published in the scientific literature involve abnormal intra-regional variability in cortical thickness affecting many (but not all) regions of the autistic brain, suggesting irregular gray matter development in autism that can be detected with MRI. Atypical developmental patterns have been detected as early as 0 years old in individuals who would later be diagnosed with autism. (shrink)

In March 2003, President Bush declared the start of Operation Iraqi Freedom, the anticipated commencement of intensive American-led military operations in Iraq. With this declaration, the media began intense coverage of military operations from the field. For the first time, viewers were able to see images of actual events. This was due to three developments: the advancement of technology allowing immediate transmission of text and images, the actual presence of journalists identified as "embedded journalists" at military sites, and the fierce (...) competition among networks for viewers. One result of this constant coverage was significant pressure on decision makers within the television and cable news networks to decide within a matter of seconds which images to air. In particular, producers and broadcasters of competing networks experienced this pressure. Though the radio and broadcasting industry has a published code of standards, it is "general and advisory rather than specific and restrictive." Therefore, it did not address the unique time sensitive decision-making required within this new environment. Issues such as the security of soldiers, confidentiality of troop maneuvers, and the safety of the embedded journalists were critically important. Equally serious were the concerns about the impact of the immediate airing of information and violent images to the public. This research used Patrick Primeaux's ' mind-heart-sou¾ model of decision-making as its theoretical framework. The study investigated the gender and industry experience of selected professionals in a cable news network, MSNBC, to explore how ethical codes of behavior are integrated when people make decisions. Decision-making in both their professional and personal lives was examined. It is from this perspective that their professional decisions to air/not to air material from Operation Iraqi Freedom were studied. The findings on decisions about airing/not airing material from Operation Iraqi Freedom yielded both expected and unexpected results. There was no clear gender difference regarding ethical decision-making, but there was a difference when analyzed by industry experience. When the study focused on questions regarding the respondents' personal lives, the original hypothesis that there was a gender difference was validated. (shrink)

MacDonald and Kreitman (1991) propose a test of the neutral mutationrandom drift (NM-RD) hypothesis, the central claim of the neutral theory of molecular evolution. The test involves generating predictions from the NM-RD hypothesis about patterns of molecular substitutions. Alternative selection hypotheses predict that the data will deviate from the predictions of the NM-RD hypothesis in specifiable ways. To conduct the test Mac- Donald and Kreitman examine the evolutionary dynamics of the alcohol dehydrogenase (Adh) gene in three species of Drosophila. (...) The test compares the number of DNA sequence changes between species and within species. The number of DNA differences is an indicator of the evolutionary rate of the Adh gene. Based on the test they conclude that there is strong evidence for adaptive protein evolution at particular sites in the gene. Understanding the test requires some basic knowledge about molecular terms and the predictions of neutral theory. The two important terms are fixed differences and polymorphisms. These are determined by comparing DNA sequences made up of thousands of individual nucleotide sites. A site that is unchanged within a species but different from a related species counts as a fixed difference. These are mutations that occur in some common ancestor of the lineage such that all descendants inherit the change. A site that differs within a species counts as a polymorphism. Determining the number of fixed differences and polymorphisms requires placing 1 each individual gene sequence onto a phylogenetic tree. A coalescent tree charts the ancestral relationships for a set of individual gene sequences. Sequences sampled from within a species form a within-species tree. The common ancestors of each within-species tree form a between-species tree. A detected difference counts as a polymorphism or a fixed difference depending on where it occurs in the phylogenetic tree (cf. Table 1). The test uses the numbers of polymorphisms and fixed differences as indicators of evolutionary rates.. (shrink)

Who wants to be a hero? -- Everyone can help -- A best friend to all -- Locked up! -- Keeping a promise -- Dream big -- Say cheese! -- In the wild -- How you can help.

Profoundly important ethical and political controversies turn on the question of whether biological life is an essential aspect of a human person, or only an extrinsic instrument. Lee and George argue that human beings are physical, animal organisms - albeit essentially rational and free - and examine the implications of this understanding of human beings for some of the most controversial issues in contemporary ethics and politics. The authors argue that human beings are animal organisms and that their personal identity (...) across time consists in the persistence of the animal organisms they are; they also argue that human beings are essentially rational and free and that there is a radical difference between human beings and other animals; criticize hedonism and hedonistic drug-taking; present detailed defenses of the prolife positions on abortion and euthanasia; and defend the traditional moral position on marriage and sexual acts. (shrink)

Conspiracy theories are rather a popular topic these days, and a lot has been written on things like the meaning of _conspiracy theory_, whether it’s ever rational to believe conspiracy theories, and on the psychology and demographics of people who believe conspiracy theories. But very little has been said about why people might be led to posit conspiracy theories in the first place. This paper aims to fill this lacuna. In particular, I shall argue that, in open democratic societies, citizens (...) justifiably presuppose that the epistemic authorities—journalists, academics, scientists, and so on—are engaged in a good faith pursuit of the truth. This presupposition generates certain normative expectations on the behaviors of the epistemic authorities—they ought to be open to new evidence, possess a healthy degree of skepticism, be willing to engage with opponents, and so on. So, when an epistemic authority is presented with some putatively anomalous data or an alternative hypothesis for some event or phenomena, people expect the epistemic authority to respond in a way that is consonant with these norms. In some instances, however, the epistemic authorities do not respond in this way and instead are dogmatic, dismissive, and engage in _ad hominem_. From the point of view of the citizen, there’s a tension here between how the epistemic authorities ought to behave and how they have, in fact, behaved which is best resolved either by taking the epistemic authorities less seriously or by positing a conspiracy theory. Put another way, the failure of the epistemic authorities to adhere to the norms by which we take them to be governed when presented with apparent anomalies or alternative hypotheses is one reason for which one might initially posit a conspiracy theory. (shrink)

Learn to think critically with the leading introduction to reasoning and argumentation. Highlights In clear, reader-friendly language, The Power of Critical Thinking provides an engaging introduction to argumentation, deductive and inductive reasoning, inferencing, and evaluating scientific theories New Critical Thinking and the Media boxes in each chapter apply the principles of critical thinking to the realms of media, advertising, and news New content on "fake news," the COVID-19 pandemic, and other important contemporary topics reflects the changing world in which today's (...) students must apply their critical thinking abilities New and updated exercises offer extensive opportunities for students to practise the skills through which they will become active, engaged critical thinkers Additional online resources-including a study guide and practice quizzes for students as well as an instructor's manual, a test bank, and PowerPoint slides for instructors-offer stimulating materials to enhance the learning and teaching experiences. About the Authors Chris MacDonald is an associate professor and chair of the Law and Business Department at the Ted Rogers School of Management, Toronto Metropolitan University. Lewis Vaughn is an independent scholar and author of several textbooks on philosophy, ethics, and critical thinking. (shrink)

Our day-to-day experience of the world regularly brings us into contact with middlesized objects such as apples, dogs, and other human beings. These objects possess observable properties, properties that are available or accessible to the unaided senses, such as redness and roundness, as well as properties that are not so available, such as chemical ones. Both of these kinds of properties serve as valuable sources of information about our familiar middle-sized objects at least to the extent that they enable us (...) to understand the behaviours of those objects and their effects on each other and on us. I see the apple on the table before me, and in doing so I see its redness, its roundness, and so on. I do not see, but know that it has, a certain chemical constitution. The knowledge gained of the apple by means of both properties tells me something about the nature of that apple. In general, most, if not all, of the properties that objects in the observable world possess serve as the basis of our knowledge of such objects. But the subject-predicate form of much of our discourse and thought about objects suggests that substances are one kind of thing, properties another. We use subject terms such as names to identify objects, predicate terms to attribute properties to them. What, then, is it for an object to have a property? And what is the relation between an object and its properties? (shrink)

Reading W.K. Clifford’s “The Ethics of Belief” in evidentialist terms is standard. However, evidentialist accounts face several longstanding interpretive issues over the Shipowner Story and Clifford’s Motto. This article defends an evidentialist reading. But what distinguishes it from others is that it interprets “The Ethics of Belief” according to Clifford’s “first principle of natural ethics”, a principle he articulates in prior writings, and which comes down to social trust. I reorient Clifford’s evidentialism by returning to his core moral principle and (...) argue that doing so can establish coherence across Clifford’s writings on ethics and can help resolve the relevant interpretive issues. (shrink)

In §2-4, I survey three extant ways of making sense of indeterminate truth and find each of them wanting. All the later sections of the paper are concerned with showing that the most promising way of making sense of indeterminate truth is via either a theory of truthmaker gaps or via a theory of truthmaking gaps. The first intimations of a truthmaker–truthmaking gap theory of indeterminacy are to be found in Quine (1981). In §5, we see how Quine proposes to (...) solve Unger’s problem of the many via positing the possibility of groundless truth. In §6, I elaborate the truthmaker gap model of indeterminacy first sketched by Sorensen (2001, ch.11) and use it to give a reductive analysis of indeterminate truth. In §7, I briefly assess what kind of formal framework can best express the possibility of truthmaker gaps. In §8, I contrast what I dub ‘the ordinary conception of worldly indeterminacy’ with Williamson’s conception of worldly indeterminacy. In §9, I show how one can distinguish linguistic from worldly indeterminacy on a truthmaker gap conception. In §10, I briefly sketch the relationship between truthmaker gaps and ignorance. In §11, I assess whether a truthmaker gap conception of vagueness is really just a form of epistemicism. In §12, I propose that truthmaker gaps can yield a plausible model of (semantic) presupposition failure. In §13, in response to the worry that a truthmaker gap conception of indeterminacy is both parochial and controversial—since it commits us to an implausibly strong theory of truthmaking—I set forth a truthmaking gap conception of indeterminacy. In §14, I answer the worry that groundless truths, of whatever species, are just unacceptably queer. A key part of this answer is that a truthmaker–truthmaking gap model of indeterminacy turns out to be considerably less queer than any model of indeterminacy which gives up on Tarski’s T-schema for truth (and cognate schemas). (shrink)

There has been increasing attention in sociology and internet studies to the topic of ‘digital remains’: the artefacts users of social network services (SNS) and other online services leave behind when they die. But these artefacts also pose philosophical questions regarding what impact, if any, these artefacts have on the ontological and ethical status of the dead. One increasingly pertinent question concerns whether these artefacts should be preserved, and whether deletion counts as a harm to the deceased user and therefore (...) provides pro tanto reasons against deletion. In this paper, I build on previous work invoking a distinction between persons and selves to argue that SNS offer a particularly significant material instantiation of persons. The experiential transparency of the SNS medium allows for genuine co-presence of SNS users, and also assists in allowing persons (but not selves) to persist as ethical patients in our lifeworld after biological death. Using Blustein’s “rescue from insignificance” argument for duties of remembrance, I argue that this persistence function supplies a nontrivial (if defeasible) obligation not to delete these artefacts. Drawing on Luciano Floridi’s account of “constitutive” information, I further argue that the “digital remains” metaphor is surprisingly apt: these artefacts in fact enjoy a claim to moral regard akin to that of corpses. (shrink)

Abstract: There is no such thing as ‘the’ hylemorphic account of personal identity. There are several views that count as hylemorphic, and these views can be grouped into two main families—the corruptionist view, and the survivalist view. The differentiating factor is that the corruptionist view holds that the persistence of the soul is not sufficient for the persistence of the person, while the survivalist view holds that the persistence of the soul is sufficient for the persistence of the person. In (...) this paper, I argue that hylemorphists should prefer the corruptionist view. This project ought to be of interest to anyone working on issues of personal identity, not only because hylemorphic views are historically important, but also because they are currently receiving significant attention in the personal identity literature. (shrink)

Adorno's remarks on the philosophy of history are scattered throughout his works. Perhaps the most important passages are to be found in Negative Dialectics and the 1964–1965 lectures on History and Freedom, as well as in texts such as Dialectic of Enlightenment and the essays on “The Idea of Natural‐History,” “Progress,” and “The Meaning of Working through the Past.” However, these works do not constitute anything like a complete theory. Nevertheless, many themes and references recur in Adorno's writings, allowing for (...) a selectively thematic reconstruction of the most central lines of argument. The present text brings together a few concepts and problems from Adorno's readings of Kant, Hegel, and Marx, mainly, in order to provide the reader with a general picture of what is at issue. (shrink)

Tens of thousands of students have learned to be more discerning at constructing and evaluating arguments with the help of Patrick J. Hurley. Hurley’s lucid, friendly, yet thorough presentation has made A CONCISE INTRODUCTION TO LOGIC the most widely used logic text in North America. In addition, the book’s accompanying technological resources, such as CengageNOW and Learning Logic, include interactive exercises as well as video and audio clips to reinforce what you read in the book and hear in class. (...) In short, you’ll have all the assistance you need to become a more logical thinker and communicator. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version. (shrink)

This collection of essays explores the conflictual history and future implications of two important traditions of twentieth-century European thought: the ...

Since St. Thomas Aquinas holds that death is a substantial change, a popular current interpretation of his anthropology must be mistaken. According to that interpretation – the ‘survivalist’ view – St. Thomas holds that we human beings survive our deaths, constituted solely by our souls in the interim between death and resurrection. This paper argues that St. Thomas must have held the ‘corruptionist’ view: the view that human beings cease to exist at their deaths. Certain objections to the corruptionist view (...) are also met. (shrink)

This chapter contains section titles: Introduction Section 1 Section 2 Conclusion.

Presents an historical analysis of social contract theory by considering the works of prominent philosophers.

Provides a methodology for the emerging area of screen production research and research-creation from a cine-ethnomusicological perspective.

This chapter contains sections titled: Gardens and Enchantment Dumbarton Oaks: A Fusion of Nature and Art? Dumbarton Oaks as a Site of Enchantment: Crossings, Complexity, and Circuits Cultivating Enchantment Notes.

Quantum mechanical entangled configurations of particles that do not satisfy Bell’s inequalities, or equivalently, do not have a joint probability distribution, are familiar in the foundational literature of quantum mechanics. Nonexistence of a joint probability measure for the correlations predicted by quantum mechanics is itself equivalent to the nonexistence of local hidden variables that account for the correlations (for a proof of this equivalence, see Suppes and Zanotti, 1981). From a philosophical standpoint it is natural to ask what sort of (...) concept can be used to provide a “joint” analysis of such quantum correlations. In other areas of application of probability, similar but different problems arise. A typical example is the introduction of upper and lower probabilities in the theory of belief. A person may feel uncomfortable assigning a precise probability to the occurrence of rain tomorrow, but feel comfortable saying the probability should be greater than ½ and less than ⅞. Rather extensive statistical developments have occurred for this framework. A thorough treatment can be found in Walley (1991) and an earlier measurement-oriented development in Suppes (1974). It is important to note that this focus on beliefs, or related Bayesian ideas, is not concerned, as we are here, with the nonexistence of joint probability distributions. Yet earlier work with no relation to quantum mechanics, but focused on conditions for existence has been published by many people. For some of our own work on this topic, see Suppes and Zanotti (1989). Still, this earlier work naturally suggested the question of whether or not upper and lower measures could be used in quantum mechanics, as a generalization of.. (shrink)

In this article, I explore how orthodox Christian theology informs a philosophical understanding of the mind-world relationship. First, I contend that the Christian doctrine of creation entails that the world possesses an intrinsic rationality and intelligibility. I then go on to show how three different views of the mind-world relationship are compatible with this fact about the world: (a) realism, (b) idealism, and (c) fallibilism. I also delineate the strengths of each view, in terms of how well each view comports (...) with other basic tenets of Christian orthodoxy. Finally, I show how fallibilism and idealism are incompatible with other important Catholic doctrines, which in turn leads me to recommend realism as the most viable position on the mind-world relationship for the Catholic philosopher to take. (shrink)

This volume explores the ethical dimensions of a wide selection of philosophical and theological topics in Aquinas's texts.

Moral latitude is only ever a matter of coincidence on the most popular decision procedure in the literature on moral uncertainty. In all possible choice situations other than those in which two or more options happen to be tied for maximal expected choiceworthiness, Maximize Expected Choiceworthiness implies that only one possible option is uniquely appropriate. A better theory of appropriateness would be more sensitive to the decision maker’s credence in theories that endorse agent-centred prerogatives. In this paper, we will develop (...) and defend a modified version of this view that allows for agent-centred prerogatives and supererogation as part of its verdicts about appropriateness. (shrink)

Epistemic contextualism is a recent and hotly debated position. In its dominant form, EC is the view that the proposition expressed by a given knowledge sentence depends upon the context in which it is uttered. What makes this view interesting and controversial is that ‘context’ here refers, not to certain features of the putative subject of knowledge or his/her objective situation, but rather to features of the knowledge attributor' psychology and/or conversational-practical situation. As a result of such context-dependence, utterances of (...) a given such sentence, made in different contexts, may differ in truth value. (shrink)

We examine cases of emergent behavior in physics, and argue for an account of emergence based on features of the phase space portraits of certain dynamical systems. On our account, the phase space portraits of systems displaying emergent behavior are topologically inequivalent to those of the systems from which they ‘emerge’. This account gives us an objective sense in which emergent phenomena are qualitatively novel, without involving the difficulties associated with downward causation and the like. We also argue that the (...) role of complexity in emergence has been overstated: emergent behavior can occur in very simple systems, and even when it occurs in complex systems it is the qualitative novelty of that behavior, rather that the complexity of the system, that matters for emergence. (shrink)

It has been argued that St. Thomas Aquinas’s anthropological views fall prey to the problem of “Too Many Thinkers.” The worry, roughly, is that his views entail that I—a human person—am able to think, but that my soul—which is not a human person—is also able to think. Hence, too many thinkers: there are too many ofus having my thoughts. In this paper, I show why this is not a problem for St. Thomas. Along the way, I also address Peter Unger’s (...) argument for substance dualism. (shrink)

The present paper revisits the debate between realists about gravitational energy in GR and anti-realists/eliminativists. I re-assess the arguments underpinning Hoefer’s seminal eliminativist stance, and those of their realist detractors’ responses. A more circumspect reading of the former is proffered that discloses where the so far not fully appreciated, real challenges lie for realism about gravitational energy. I subsequently turn to Lam and Read’s recent proposals for such a realism. Their arguments are critically examined. Special attention is devoted to the (...) adequacy of Read’s appeals to functionalism, imported from the philosophy of mind. (shrink)