The Clinical ethics centre in Paris offers its services equally to doctors and patients/proxies. Its primary goal is to re-equilibrate doctor–patient roles through giving greater voice to patients individually in medical decisions. Patients are present at virtually all levels, initiating consults, providing their point of view and receiving feedback. The implications of patients' involvement are threefold. At an operational level, decision-making is facilitated by repositioning the debate on ethical grounds and introducing a dynamic of decisional partnership, although contact with patients (...) can make it difficult to deny their demands and set the limits of our role. Ethically, it reinforces patients' autonomy and grants them a place of veritable ethics ‘actors’, with the danger that this may become excessively autonomy oriented. Finally, at a collective level, the programme fulfils its political purpose in promoting patients' rights and the ideal of démocratie sanitaire, but complicates balancing individual demands with collective values. (shrink)

With complex buyer-driven global production networks and a labour-intensive manufacturing process, the fashion industry has become a focal point for debates on the social responsibility of business. Utilising an interview methodology with influential actors from seven export garment manufacturers in Sri Lanka, we explore the situated knowledge at one nodal point of the production network. We conceptualise factory management perspectives on the implementation of corporate social responsibility in terms of the strategic balancing of ethical considerations against the commercial pressures of (...) cost and lead time. Factory managers framed CSR in terms of compliance, rather than going above and beyond regulatory requirements; seeing it as a strategic competitive imperative and less a developmental mechanism. Sri Lankan manufacturers maintain that they have benefitted from a unique combination of factors, including strict national labour laws, an educated workforce, the characteristics of the garments produced, industrial upgrading, and long-term non-adversarial buyer–supplier relationships, which they argue has supported the establishment and maintenance of CSR practices. The paper thus provides managerial implications that relate CSR activities to CSR outcomes which include both reputational and production benefits. Such insights will be of strategic relevance for lead retail buyers as well as apparel producers keen to invest in CSR to partly mitigate against increasing price-based competition. (shrink)

La polifonía, vista como la coexistencia de distintas voces en un texto, guarda una estrecha relación con el pluralismo de voces, uno de los deberes del periodismo. Paralelamente, los medios de comunicación buscan ejercer influencia social, velando por sus intereses y los de las élites, especialmente en los editoriales, donde por excelencia se emite el discurso del medio. Ahora bien, las protestas sociales, al buscar el posicionamiento de ciertos temas en el espacio público, desafían la capacidad de pluralismo de los (...) medios. En el estallido chileno de 2019, el discurso periodístico fue crucial en el debate público sobre el delito, un tema clave para entender la legitimidad de la protesta social y que informa sobre el rol de los medios en el debate público. Al respecto, nos preguntamos: ¿Cómo se expresa el pluralismo de voces en los editoriales que versan sobre el delito en los dos diarios de referencia nacional durante el primer mes de la revuelta chilena de 2019? Nuestro objetivo es caracterizar el pluralismo de voces en el discurso sobre el delito en el contexto de la revuelta chilena del 2019, a través de la descripción de polifonía en el género editorial. Mediante el análisis cualitativo de un corpus de editoriales que versan sobre el delito en el contexto del estallido chileno del 2019, se identifican los actores cuya voz está presente en el corpus y se caracterizan sus enunciados. Como resultado, emergen seis modos de entrelazar los enunciados y el impacto que tienen las características polifónicas como modalidades discursivas en promover la postura del editorialista y el medio. La tendencia es de una polifonía más bien disfrazada que responde a las restricciones del género, empleada con fines persuasivos para promover, principalmente, un discurso de élite respecto a lo social. (shrink)

This book explores repetition in contemporary performance and spectatorship. It offers an impassioned account of the ways in which speech, movement and structures repeat in performances by Pina Bausch, Anne Teresa De Keersmaeker, Lone Twin Theatre, Haranczak/Navarre and Marco Berrettini. It addresses repetition in relation to processes of desire and draws attention to the forces that repetition captures and makes visible. What is it in performances of repetition that persuades us to return to them again and again? How might we (...) unpack their complexities and come to terms with their demands upon us? While considering repetition in relation to the difficult pleasures we derive from the theatre, this book explores ways of accounting for such experience of theatre in memory and writing--back cover. (shrink)

Mitochondria hold diverse and pivotal roles in fundamental processes that govern cell survival, differentiation, and death, in addition to organismal growth, maintenance, and aging. The mitochondrial protein import system is a major contributor to mitochondrial biogenesis and lies at the crossroads between mitochondrial and cellular homeostasis. Recent findings highlight the mitochondrial protein import system as a signaling hub, receiving inputs from other cellular compartments and adjusting its function accordingly. Impairment of protein import, in a physiological, or disease context, elicits adaptive (...) responses inside and outside mitochondria. In this review, we discuss recent developments, relevant to the mechanisms of mitochondrial protein import regulation, with a particular focus on quality control, proteostatic and metabolic cellular responses, triggered upon impairment of mitochondrial protein import. (shrink)

This contribution showcases the work of the Vienna Euchologia Project which aims to make accessible the ‘small prayers’ or ‘occasional prayers’ that are preserved in the Byzantine euchologia manuscripts from the late 8th to the mid 17th century as sources for daily life and social history. A brief introduction to the project is followed by three thematically focused studies that juxtapose the prescriptive prayers in the euchologia with descriptive evidence from other sources: exorcism and other prayers in hagiographical narratives, prayers (...) with relevance to political history, and prayers relating to women’s purity. (shrink)

On the 7th of June 2018, The National Archives UK held its inaugural digital lecture, delivered by Professor Luciano Floridi entitled “Semantic Capital: What it is and how to protect it”. The lecture was followed by a poster exhibition, showcasing nine cutting-edge digital research projects at The National Archives. This paper aims at giving a distinct overview of The National Archives’ digital research priorities, drawing on examples from the active and recently completed research projects, which were displayed at the exhibition (...) on the 7th of June 2018. The focus of this paper is to discuss the research challenges that we are facing as we seek to become a second-generation digital archive, that is digital by instinct and design. By placing a particular emphasis on the conceptual and epistemological challenges relating to trust and openness, the paper suggests that research is the key for us as a rapidly evolving digital archive; enabling us not only to inform but also innovate around the forthcoming digital challenges, and helping us to define future directions and lead the shaping of the future archive. (shrink)

This paper focuses on the 12th-century Byzantine scholar Michael Glykas and the two main pillars of his multifarious literary production, Biblos Chronike and Letters, thoroughly exploring for the first time the nature of their interconnection. In addition to the primary goal, i. e. clarifying as far as possible the conditions in which these two works were written, taking into account their intertextuality, it extends the discussion to the mixture of features in texts of different literary genre, written in parallel, by (...) the same author, based on the same material. By presenting the evidence drawn from the case of Michael Glykas, the paper attempts to stress the need to abandon the strictly applied taxonomical logic in approaching Byzantine Literature, as it ultimately prevents us from constitute the full mark of each author in the history of Byzantine culture. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Ethics & the Environment 8.1 (2003) 57-60 [Access article in PDF] The Art of Impurity Patsy Hallen I was taken aback when I received a request from the West Australian government to write a response to the question, "What Is The Ethical Foundation For Planning A More Sustainable Future?" My first reaction was: Does not every one want a future? And doesn't this necessarily mean a commitment to sustainability? (...) Would not everyone earnestly want a more sustainable future?To have to ask the question at all shows just how far out of balance our crazy, greed-driven culture is. To ask the question is to imply that many people do not want to live on, or, at least, do not want the next generation to live on. It was like being asked: How can one morally justify a flourishing, joyful life for every being on earth?In a profound sense, there cannot and need not be any moral justification for sustainability because sustainability is the foundation for morality, not the other way around. As the ancient Greek philosopher Aristotle cautioned, it shows a lack of education to try and prove everything. You can't prove logic, for example, because logic presupposes proof. Likewise, our ultimate norms such as "Love is better than hate" must be gained by intuition; they can't be proved.No sooner had I received this request than I became ill (no causal connection, I assure you!) and in my fever-induced reveries I penned imaginary responses. I wrote:"The Ethical Foundation of Sustainability is 'Joy' or 'Life' or 'An Ethic of Flourishing'." [End Page 57]'Survival' seemed the most appropriate candidate (especially as the fever escalated), until I settled on Love.Of course, Love.* * *He was huge. He was unbelievably huge. He just kept coming and coming. He was so close.His blue-grey body turned the intensely deep blue depths into a translucent green, like an enormous halo hovering just below the surface.I was drawn into his presence like ink into blotting paper.He blew, rhythmically expelling air. I, too, exhaled and this made me 'come to', returning me to my body. I realized I was wet-by his breath. I had been baptized, the most magnificent baptism one could imagine.In my baptism, luckily, I was spared being hit by a dollop of phlegm.It does happen.His breath smelt... not sweet but not sour-primordial, like the origin of life. I became aware of someone softly counting the breaths: "17... 18... 19..." it seemed everlasting.Then after 19 breaths, he dove, not with a rush, just leisurely, almost seamlessly, like the pulse of life itself, hardly a splash.I hadn't even remembered to be seasick.He is one of the largest animals ever to have lived on earth. His tongue weighs more than an elephant. He measures a length of 26 meters, a weight of around 160 tons.This is the Pygmy Blue Whale, Balaenoptera Brevicanda, hunted close to extinction by the whaling industry, and now slowly returning from the brink. Whoever named him "Pygmy" must have had delusions of grandeur.We were 30 nautical miles off the west end of Rottenest Island (near Perth), on board "Whalesong," a 13-meter catamaran built and sailed by Curt and Mich Jenner, who have been researching whales on the West Australian coast for over 10 years.We were at "the trench," where Pygmies feed. Mich and Curt had spent the summer trying to learn about this Rorqual Whale, before sailing north for the winter to follow Humpbacks on their annual migratory path from their feeding grounds in the southern ocean to their breeding enclaves in the Kimberley.Very little is known about Pygmy Blues. They are a tropical subspecies of the Blue Whale, but might possibly be a new species altogether. No one [End Page 58] knows where they go to mate or to give birth. Very few people have even seen them. Like the Whale Sharks, they are one of the last unfathomable mysteries of the planet.We stayed with this foundational animal for 2 hours, until the last... (shrink)

One of the major criticisms of optimal foraging theory (OFT) is that it is not testable. In discussions of this criticism opposing parties have confused methodological concepts and used meaningless biological concepts. In this paper we discuss such misunderstandings and show that OFr has an empirically testable, and even well-confirmed, general core theory. One of our main conclusions is that specific model testing should not be aimed at proving optimality, but rather at identifying the context in which certain types of (...) behaviour are optimal. To do this, it is necessary to be aware of the assumptions made in testing a model. The assumptions that are explicitly stated in the literature up to now do not completely cover the actual assumptions made in testing OFT models in practice. We present a more comprehensive set of assumptions. Although all the assumptions play a role in testing models, they are not of equal status. Crucial assumptions concern constraints and the relation between fitness and currency. Therefore, it is essential to make such assumptions testable in practice. We show that a more explicit relationship between OFT modelling and evolutionary theory can help with this. Specifically, phylogeny reconstruction and population dynamic modelling can and should be used to formulate assumptions concerning constraints and currencies. (shrink)

One of the major criticisms of optimal foraging theory is that it is not testable. In discussions of this criticism opposing parties have confused methodological concepts and used meaningless biological concepts. In this paper we discuss such misunderstandings and show that OFr has an empirically testable, and even well-confirmed, general core theory. One of our main conclusions is that specific model testing should not be aimed at ‘proving’ optimality, but rather at identifying the context in which certain types of behaviour (...) are optimal. To do this, it is necessary to be aware of the assumptions made in testing a model. The assumptions that are explicitly stated in the literature up to now do not completely cover the actual assumptions made in testing OFT models in practice. We present a more comprehensive set of assumptions. Although all the assumptions play a role in testing models, they are not of equal status. Crucial assumptions concern constraints and the relation between fitness and currency. Therefore, it is essential to make such assumptions testable in practice. We show that a more explicit relationship between OFT modelling and evolutionary theory can help with this. Specifically, phylogeny reconstruction and population dynamic modelling can and should be used to formulate assumptions concerning constraints and currencies. (shrink)

Clinical ethics has developed significantly in Europe over the past 15 years and remains an evolving process. While sharing our experiences in different European settings, we were surprised to discover marked differences in our practice, especially regarding the position and role of patients. In this paper, we describe these differences, such as patient access to and participation or representation in ethics consults. We propose reasons to explain these differences, hypothesizing that they relate to the historic and sociocultural context of implementation (...) of clinical ethics consultation services (Cecs), as well as the initial aims for which each structure was established. Then, we analyse those differences with common ethical arguments arising in patient involvement. We conclude that there is no unique model of best practice for patient involvement in clinical ethics, as far as Cecs reflect on how to deal with the challenging ethical issues raised by patient role and position. (shrink)

Thomas Hobbes based his natural philosophy on definitions and general principles of matter in motion, which he refrained from calling “laws of nature.” Across the channel, René Descartes had presented his own account of matter in motion in such a way that laws of nature play a central causal-explanatory role. Despite some notable differences in the two systems of natural philosophy, the content of the three Cartesian laws of nature is shared by Hobbesian principles of motion. Why is it the (...) case that Hobbes never ‘transferred’ the concept of law of nature from the sphere of civil society to the realm of nature? What is the status of the Hobbesian principles of motion if they are not laws? Answering these questions is the main aim of this article. It is shown that Hobbes made available an importantly different and genuinely original way to do natural philosophy, which renders it free of metaphysics and eschews the need to ground it in anything other than ‘natural reason’. Briefly put, Hobbes took the category of ‘laws of nature’ to involve commitments that cannot be met in the natural world, unless natural philosophy loses its autonomy from theology and metaphysics. (shrink)

In the context of a viral outbreak and necessary physical distancing, the emergence of new or the evolution of older artistic behavioural schemes becomes evident. We correlate the isolation space of the artist with the cockpit of a spaceship and the navigation and communication interfaces used by an astronaut. The cybernetic domain between physical space(s) and artist(s) can be thought of as consisting of many ‘organs’. It includes a core (black box), many-layered limits: skin, walls, mental and digital borders as (...) well as mechanisms of connectivity with external entities (other astronauts in art spaceships). This space could be a bedroom, a studio, an office or any different location the artist uses as an isolated bubble of information sharing and manipulation (material and immaterial). For the construction of such an (astronaut, artist) ontology we use metaphors, etymological references, transformed concepts and creative analogies between the actual and the subjective space. As one case study for this paradigm, we experimented with a telematic performance of Heiner Müller’s Hamlet Machine titled, I want to be 171. (shrink)

This study obtained data about faculty attitudes on the ethical propriety of and estimated involvement with 38 activities. A questionnaire, mailed to 480 randomly selected Information Systems (IS) academicians provided insights into the ethical standards held by IS faculty. Several attitudinal differences, based upon individual and institutional demographic characteristics were identified. The most discriminating individual characteristic explaining differences in faculty attitudes was appointment level. The IS major at the graduate level explained more differences in attitude and more critical attitudes than (...) any other factor. (shrink)

Nonbelievers represent an understudied population in Greece. This investigation reports on the translation, cultural adaptation, and initial validation of the Nonreligious-Nonspiritual Scale, a measure designed to assess nonbelief. Data from 1754 participants were collected to examine the psychometric properties of the Greek version of the instrument and to assess the nationwide interpretability of the measure. Factor analyses suggested that the 16-item scale retained its bifactor model. Convergent validity was supported through associations with additional measures, namely, the Meaning in Life Questionnaire (...) and the Connor–Davidson Resilience Scale, which were used as reference criteria. Potential utility of the measure and future directions for ongoing development are discussed. (shrink)

Should the private sector concern itself with the health of the communities in which it operates? Should the community look to local businesses for collaboration in the effort to elevate the health of its citizens? Is there an opportunity between the public and private sectors to create shared value through the enhancement of public health? These are questions this paper explores and analyzes, using theoretical models that originate in disparate literatures.

Previous developmental research shows that young children display a preference for ingroup members when it comes to who they accept information from – even when that information is false. However, it is not clear how this ingroup bias develops into adolescence, and how it affects responses about peers who misinform in intergroup contexts, which is important to explore with growing numbers of young people on online platforms. Given that the developmental span from childhood to adolescence is when social groups and (...) group norms are particularly important, the present study took a Social Reasoning Developmental Approach. This study explored whether children and adolescents respond differently to a misinformer spreading false claims about a peer breaking COVID-19 rules, depending on the group membership of the misinformer and their target and whether the ingroup had a “critical” norm that values questioning information before believing it. 354 United Kingdom-based children and adolescents read about an intergroup scenario in which a peer spreads misinformation on WhatsApp about a competitor. Participants first made moral evaluations, which asked them to judge and decide whether or not to include the misinformer, with follow-up “Why?” questions to capture their reasoning. This was followed by asking them to attribute intentions to the misinformer. Results showed that ingroup preferences emerged both when participants morally evaluated the misinformer, and when they justified those responses. Participants were more likely to evaluate an ingroup compared to an outgroup misinformer positively, and more likely to accuse an outgroup misinformer of dishonesty. Adolescents attributed more positive intentions to the misinformer compared with children, with children more likely to believe an outgroup misinformer was deliberately misinforming. The critical norm condition resulted in children making more positive intentionality attributions toward an ingroup misinformer, but not an outgroup misinformer. This study’s findings highlight the importance of shared group identity with a misinformer when morally evaluating and reasoning about their actions, and the key role age plays in intentionality attributions surrounding a misinformer when their intentions are ambiguous. (shrink)

The present study examined British children’s and adolescents’ individual and perceived group evaluations of a challenger when a member of one’s own group excludes a British national or an immigrant newcomer to the school from participating in a group activity. Participants included British children and adolescents, who were inducted into their group and heard hypothetical scenarios in which a member of their own group expressed a desire to exclude the newcomer from joining their activity. Subsequently, participants heard that another member (...) of the ingroup challenged the exclusionary act by stating that they should be inclusive. Children’s and adolescents’ individual evaluations of the bystander who challenged the social exclusion of an immigrant peer were more positive than their perceived group evaluations, recognizing that groups are often exclusionary. Only adolescents but not children differed in their individual and perceived group evaluations in the social exclusion of British peers. When the newcomer was an immigrant peer, adolescents were more likely to evaluate the challenger positively in both their individual and perceived group evaluations compared to children. Further, children, compared to adolescents, were more likely to reason about social and group norms to justify their evaluations only when the excluded peer was an immigrant but not when the excluded peer was British. Adolescents were more likely to reason about fairness, rights, and equality. The findings indicate that exclusionary group norms surrounding immigrants begin in childhood. Interventions that focus on changing group norms to be more inclusive could be effective in reducing prejudicial attitudes toward immigrants in childhood. (shrink)

Viruses are essentially composed of a nucleic acid (segmented or not, DNA, or RNA) and a protein coat. Despite their simplicity, these small pathogens are responsible for significant economic and humanitarian losses that have had dramatic consequences in the course of human history. Since their discovery, scientists have developed different strategies to efficiently detect viruses, using all possible viral features. Viruses shape, proteins, and nucleic acid are used in viral detection. In this review, the development of these techniques, especially for (...) plant and mammalian viruses, their strengths and weaknesses as well as the latest cutting-edge technologies that may be playing important roles in the years to come are described. (shrink)