14 found
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  1.  95
    Ethics and Epistemology in Big Data Research.Wendy Lipworth, Paul H. Mason, Ian Kerridge & John P. A. Ioannidis - 2017 - Journal of Bioethical Inquiry 14 (4):489-500.
    Biomedical innovation and translation are increasingly emphasizing research using “big data.” The hope is that big data methods will both speed up research and make its results more applicable to “real-world” patients and health services. While big data research has been embraced by scientists, politicians, industry, and the public, numerous ethical, organizational, and technical/methodological concerns have also been raised. With respect to technical and methodological concerns, there is a view that these will be resolved through sophisticated information technologies, predictive algorithms, (...)
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  2.  32
    Degeneracy at Multiple Levels of Complexity.Paul H. Mason - 2010 - Biological Theory 5 (3):277-288.
    Degeneracy is a poorly understood process, essential to natural selection. In the 18th and 19th centuries, the concept of degeneracy was commandeered by the colonial imagination. A rigid understanding of species, race, and culture grew to dominate the normative thinking that persisted well into the burgeoning new industrial age. A 20th-century reconfiguration of the concept by George Gamow highlighted a form of intraorganismic variation that is still underexplored. Degeneracy exists in a population of variants where structurally different components perform a (...)
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  3.  21
    Degeneracy: Demystifying and destigmatizing a core concept in systems biology.Paul H. Mason - 2015 - Complexity 20 (3):12-21.
  4.  22
    Ethics and Epistemology of Big Data.Ian Kerridge, Paul H. Mason & Wendy Lipworth - 2017 - Journal of Bioethical Inquiry 14 (4):485-488.
    In this Symposium on the Ethics and Epistemology of Big Data, we present four perspectives on the ways in which the rapid growth in size of research databanks—i.e. their shift into the realm of “big data”—has changed their moral, socio-political, and epistemic status. While there is clearly something different about “big data” databanks, we encourage readers to place the arguments presented in this Symposium in the context of longstanding debates about the ethics, politics, and epistemology of biobank, database, genetic, and (...)
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  5.  89
    Ethics and Epistemology of Big Data.Ian Kerridge, Paul H. Mason & Wendy Lipworth - 2017 - Journal of Bioethical Inquiry 14 (4):485-488.
    In this Symposium on the Ethics and Epistemology of Big Data, we present four perspectives on the ways in which the rapid growth in size of research databanks—i.e. their shift into the realm of “big data”—has changed their moral, socio-political, and epistemic status. While there is clearly something different about “big data” databanks, we encourage readers to place the arguments presented in this Symposium in the context of longstanding debates about the ethics, politics, and epistemology of biobank, database, genetic, and (...)
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  6.  12
    Personal Genomic Testing, Genetic Inheritance, and Uncertainty.Paul H. Mason - 2017 - Journal of Bioethical Inquiry 14 (4):583-584.
    The case outlined below is the basis for the In That Case section of the “Ethics and Epistemology of Big Data” symposium. Jordan receives reports from two separate personal genomic tests that provide intriguing data about ancestry and worrying but ambiguous data about the potential risk of developing Alzheimer’s disease. What began as a personal curiosity about genetic inheritance turns into an alarming situation of medical uncertainty. Questions about Jordan’s family tree are overshadowed by even more questions about Alzheimer’s disease (...)
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  7.  20
    Beyond Biomedicine: Relationships and Care in Tuberculosis Prevention.Paul H. Mason & Chris Degeling - 2016 - Journal of Bioethical Inquiry 13 (1):31-34.
    With attention to the experiences, agency, and rights of tuberculosis patients, this symposium on TB and ethics brings together a range of different voices from the social sciences and humanities. To develop fresh insights and new approaches to TB care and prevention, it is important to incorporate diverse perspectives from outside the strictly biomedical model. In the articles presented in this issue of the Journal of Bioethical Inquiry, clinical experience is married with historical and cultural context, ethical concerns are brought (...)
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  8.  30
    More Than One Way to Be Global: Globalization of Research and the Contest of Ideas.Paul H. Mason, Wendy Lipworth & Ian Kerridge - 2016 - American Journal of Bioethics 16 (10):48-49.
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  9.  28
    DBS as a ‘Technological Fix’ or a ‘Regime of Care’? Recognizing the Importance of Narrative Identity in Neurosurgical Services.John Gardner, Narelle Warren, Adrian Carter, Paul H. Mason & Juan Dominguez - 2017 - American Journal of Bioethics Neuroscience 8 (3):192-194.
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  10.  28
    Recognizing the Nocebo Benefits Patient Care, But Demands Greater Cultural Competency in the Clinic.Antoinette P. Joseph, Paul H. Mason, Narelle Warren & Isaac Atley - 2017 - American Journal of Bioethics 17 (6):54-56.
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  11.  23
    The Liminal Body: Comment on “Privacy in the Context of ‘Re-emergent’ Infectious Diseases” by Justin T. Denholm and Ian H. Kerridge.Paul H. Mason - 2014 - Journal of Bioethical Inquiry 11 (4):565-566.
    If James has a latent tuberculosis infection , he is at risk of developing active tuberculosis disease but he is not yet sick. LTBI is a liminal space between health and illness. Diagnosed with LTBI, James could be conceptualised as having a liminal body. Treatments for LTBI are available, but why would a person seek treatment for a disease he does not yet have? One thing is definite: James needs to be educated about the symptoms and severity of active tuberculosis (...)
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  12.  11
    Development and Public Health in the Himalaya: Reflections on Healing in Contemporary Nepal: Ian Harper, 2014, Routledge.Paul H. Mason - 2016 - Journal of Bioethical Inquiry 13 (1):163-165.
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  13.  39
    The Ethics of Biomedical Big Data: Brent Daniel Mittelstadt and Luciano Floridi, eds. 2016, Springer International Publishing.Paul H. Mason - 2017 - Journal of Bioethical Inquiry 14 (4):571-574.
    The availability of diverse sources of data related to health and illness from various types of modern communication technology presents the possibility of augmenting medical knowledge, clinical care, and the patient experience. New forms of data collection and analysis will undoubtedly transform epidemiology, public health, and clinical practice, but what ethical considerations come in to play? With a view to analysing the ethical and regulatory dimensions of burgeoning forms of biomedical big data, Brent Daniel Mittelstadt and Luciano Floridi have brought (...)
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  14.  22
    The Ethics of Biomedical Big Data: Brent Daniel Mittelstadt and Luciano Floridi, eds. 2016, Springer International Publishing.Paul H. Mason - 2017 - Journal of Bioethical Inquiry 14 (4):571-574.
    The availability of diverse sources of data related to health and illness from various types of modern communication technology presents the possibility of augmenting medical knowledge, clinical care, and the patient experience. New forms of data collection and analysis will undoubtedly transform epidemiology, public health, and clinical practice, but what ethical considerations come in to play? With a view to analysing the ethical and regulatory dimensions of burgeoning forms of biomedical big data, Brent Daniel Mittelstadt and Luciano Floridi have brought (...)
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