Our view is that fundamental appetitive and defensive motivation systems evolved to mediate a complex array of adaptive behaviors that support the organism’s drive to survive—defending against threat and securing resources. Activation of these motive systems engages processes that facilitate attention allocation, information intake, sympathetic arousal, and, depending on context, will prompt tactical actions that can be directed either toward or away from the strategic goal, whether defensively or appetitively determined. Research from our laboratory that measures autonomic, central, and somatic (...) reactions when processing emotional scenes is described which indicates that motivationally relevant cues, whether appetitive or defensive, capture attention preferentially, prompt enhanced perceptual processing and information gathering, and occasion metabolic arousal that mobilizes the organism for coping actions. (shrink)

The purpose of public and community health is to improve the health of populations or groups rather than concentrating on individuals. This book examines the ethical issues associated with public and community health. The contributors analyse the major ethical issues in public health - prioritisation, public participation, health promotion and screening - all of which reflect current practice in the UK. They examine what health services should be available, who should have access to which health services, what are the best (...) strategies for preventing disease, how can professional and public views be reconciled and when can an individual's health needs override the choice of a community. The contributors apply up-to-date ethical theory to practical examples in public health practice to provide a comprehensive and accessible introduction to the key issues in public health ethics. (shrink)

The purpose of public and community health is to improve the health of populations or groups rather than concentrating on individuals. This book examines the ethical issues associated with public and community health. The contributors analyse the major ethical issues in public health - prioritisation, public participation, health promotion and screening - all of which reflect current practice in the UK. They examine what health services should be available, who should have access to which health services, what are the best (...) strategies for preventing disease, how can professional and public views be reconciled and when can an individual's health needs override the choice of a community. The contributors apply up-to-date ethical theory to practical examples in public health practice to provide a comprehensive and accessible introduction to the key issues in public health ethics. (shrink)

This book is a collection of secondary essays on America's most important philosophic thinkers—statesmen, judges, writers, educators, and activists—from the colonial period to the present. Each essay is a comprehensive introduction to the thought of a noted American on the fundamental meaning of the American regime.

© 2015 Elsevier Inc.Toxoplasma gondii is a protozoan pathogen in the phylum Apicomplexa that resides within an intracellular parasitophorous vacuole that is selectively permeable to small molecules through unidentified mechanisms. We have identified GRA17 as a Toxoplasma-secreted protein that localizes to the parasitophorous vacuole membrane and mediates passive transport of small molecules across the PVM. GRA17 is related to the putative Plasmodium translocon protein EXP2 and conserved across PV-residing Apicomplexa. The PVs of GRA17-deficient parasites have aberrant morphology, reduced permeability to (...) small molecules, and structural instability. GRA17-deficient parasites proliferate slowly and are avirulent in mice. These GRA17-deficient phenotypes are rescued by complementation with Plasmodium EXP2. GRA17 functions synergistically with a related protein, GRA23. Exogenous expression of GRA17 or GRA23 alters the membrane conductance properties of Xenopus oocytes in a manner consistent with a large non-selective pore. Thus, GRA17 and GRA23 provide a molecular basis for PVM permeability and nutrient access. (shrink)

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories (...) and On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

Define ‘het’ as a predicate that truly applies to itself if and only if it does not truly apply to itself and which also truly applies to any predicate that does not truly apply to its own name. We know that the attempted definition of ‘hes’ is a failure, and so a fortiori is that of ‘het’. Similarly, there is no Qussell class which contains itself as a member if and only if it does not contain itself as a member, (...) so a fortiori there is no Russell Class which contains itself as a member if and only if it does not contain itself as a member and which also contains all and only non-self-membered classes (such as the class of dogs). The second conjunct in both the definition of ‘het’ and of the Russell class cannot revive a definition doomed to failure. Likewise, the ‘definition’ of n as ‘n > 1 iff n < 1’ fails, and the attempted definition of m as ‘m > 1 iff m < 1 and m is prime’ is hopeless too; its final clause buys it no respectability. (shrink)

Although the relationship of part to whole is one of the most fundamental there is, this is the first full-length study of this key concept. Showing that mereology, or the formal theory of part and whole, is essential to ontology, Simons surveys and critiques previous theories--especially the standard extensional view--and proposes a new account that encompasses both temporal and modal considerations. Simons's revised theory not only allows him to offer fresh solutions to long-standing problems, but also has far-reaching consequences for (...) our understanding of a host of classical philosophical concepts. (shrink)

The relationship of part to whole is one of the most fundamental there is; this is the first and only full-length study of this concept. This book shows that mereology, the formal theory of part and whole, is essential to ontology. Peter Simons surveys and criticizes previous theories, especially the standard extensional view, and proposes a more adequate account which encompasses both temporal and modal considerations in detail. 'Parts could easily be the standard book on mereology for the next (...) twenty or thirty years.' Timothy Williamson, Grazer Philosophische Studien. (shrink)

Introduction By the late fifth century BCE Panini had composed the Astadhyayi, consisting of nearly 4000 rules giving a precise and fairly complete ...

There are at least three things we might mean by "ethics in robotics": the ethical systems built into robots, the ethics of people who design and use robots, and the ethics of how people treat robots. This paper argues that the best approach to robot ethics is one which addresses all three of these, and to do this it ought to consider robots as socio-technical systems. By so doing, it is possible to think of a continuum of agency that lies (...) between amoral and fully autonomous moral agents. Thus, robots might move gradually along this continuum as they acquire greater capabilities and ethical sophistication. It also argues that many of the issues regarding the distribution of responsibility in complex socio-technical systems might best be addressed by looking to legal theory, rather than moral theory. This is because our overarching interest in robot ethics ought to be the practical one of preventing robots from doing harm, as well as preventing humans from unjustly avoiding responsibility for their actions. (shrink)

This paper is a review of work on Newman's objection to epistemic structural realism (ESR). In Section 2, a brief statement of ESR is provided. In Section 3, Newman's objection and its recent variants are outlined. In Section 4, two responses that argue that the objection can be evaded by abandoning the Ramsey-sentence approach to ESR are considered. In Section 5, three responses that have been put forward specifically to rescue the Ramsey-sentence approach to ESR from the modern versions of (...) the objection are discussed. Finally, in Section 6, three responses are considered that are neutral with respect to one's approach to ESR and all argue (in different ways) that the objection can be evaded by introducing the notion that some relations/structures are privileged over others. It is concluded that none of these suggestions is an adequate response to Newman's objection, which therefore remains a serious problem for ESRists. Introduction Epistemic Structural Realism 2.1 Ramsey-sentences and ESR 2.2 WESR and SESR The Objection 3.1 Newman's version 3.2 Demopoulos and Friedman's and Ketland's versions Replies that Abandon the Ramsey-Sentence Approach to ESR 4.1 Redhead's reply 4.2 French and Ladyman's reply Replies Designed to Rescue the Ramsey-Sentence Approach 5.1 Zahar's reply 5.2 Cruse's reply 5.3 Melia and Saatsi's reply Replies that Argue that Some Structures/Relations are Privileged 6.1 A Carnapian reply 6.2 Votsis' reply 6.3 The Merrill/Lewis/Psillos reply Summary CiteULike Connotea Del.icio.us What's this? (shrink)

This book with an introduction by Witold Marciszewski, views the history of philosophy and logic from 1837 to 1939 from the perspective of the cradle of modern exact philosophy - Central Europe. In a series of case studies, it illuminates the developments in this region, most notably in Austria and Poland, examining thinkers such as Bolzano, Brentano, Meinong, Husserl, Twardowski, Lesniewski, and Tarski, as well as the logicians like Frege and Russell with whom they bore a close resemblance. The book (...) challenges established views about the history of philosophy and logic in Europe, and shows the vitality of the Central European tradition. (shrink)

How can anyone be rational in a world where knowledge is limited, time is pressing, and deep thought is often an unattainable luxury? Traditional models of unbounded rationality and optimization in cognitive science, economics, and animal behavior have tended to view decision-makers as possessing supernatural powers of reason, limitless knowledge, and endless time. But understanding decisions in the real world requires a more psychologically plausible notion of bounded rationality. In Simple heuristics that make us smart (Gigerenzer et al. 1999), we (...) explore fast and frugal heuristics – simple rules in the mind's adaptive toolbox for making decisions with realistic mental resources. These heuristics can enable both living organisms and artificial systems to make smart choices quickly and with a minimum of information by exploiting the way that information is structured in particular environments. In this précis, we show how simple building blocks that control information search, stop search, and make decisions can be put together to form classes of heuristics, including: ignorance-based and one-reason decision making for choice, elimination models for categorization, and satisficing heuristics for sequential search. These simple heuristics perform comparably to more complex algorithms, particularly when generalizing to new data – that is, simplicity leads to robustness. We present evidence regarding when people use simple heuristics and describe the challenges to be addressed by this research program. Key Words: adaptive toolbox; bounded rationality; decision making; elimination models; environment structure; heuristics; ignorance-based reasoning; limited information search; robustness; satisficing; simplicity. (shrink)

The relationship of part to whole is one of the most fundamental there is, yet until now there has been no full-length study of this concept. This book shows that mereology, the formal theory of part and whole, is essential to ontology. Peter Simons surveys and criticizes previous theories, especially the standard extensional view, and proposes a more adequate account which encompasses both temporal and modal considerations in detail. This has far-reaching consequences for our understanding of such classical philosophical (...) concepts as identity, individual, class, substance and accident, matter, form, essence, dependence, and integral whole. It also enables the author to offer new solutions to long-standing problems surrounding these concepts, such as the Ship of Theseus Problem and the issue of mereological essentialism. The author shows by his use of formal techniques that classical philosophical problems are amenable to rigorous treatment, and the book represents a synthesis of issues and methods from the analytical tradition and from the older continental realist tradition of Brentano and the early Husserl. (shrink)

The paper is concerned with the idea that the world is the totality of facts, not of things – with what is involved in thinking of the world in that way, and why one might do so. It approaches this issue through a comparison between Wittgenstein’s Tractatus and the identity theory of truth proposed by Hornsby and McDowell.The paper’s positive conclusion is that there is a genuine affinity between these two. A negative contention is that the modern identity theory is (...) vulnerable to a complaint of idealism that the Tractatus can deflect. (shrink)

Traditional views of rationality posit general-purpose decision mechanisms based on logic or optimization. The study of ecological rationality focuses on uncovering the “adaptive toolbox” of domain-specific simple heuristics that real, computationally bounded minds employ, and explaining how these heuristics produce accurate decisions by exploiting the structures of information in the environments in which they are applied. Knowing when and how people use particular heuristics can facilitate the shaping of environments to engender better decisions.

For most of the history of metaphysics, the subject has been dominated by the concept of substance. There is an everyday commonsense notion of substance which is perfectly harmless and which I shall defend against attempts to remove it or revise it away. But I deny that substance has to be construed as a primitive even in everyday terms. Borrowing Strawson’s distinction between descriptive and revisionary metaphysics, I press the legitimate claims of revisionary metaphysics and argue that there is no (...) place for a fundamental concept of substance within it, although aspects of the concept are likely to find their place therein. (shrink)

While theories of rationality and decision making typically adopt either a single-powertool perspective or a bag-of-tricks mentality, the research program of ecological rationality bridges these with a theoretically-driven account of when different heuristic decision mechanisms will work well. Here we described two ways to study how heuristics match their ecological setting: The bottom-up approach starts with psychologically plausible building blocks that are combined to create simple heuristics that fit specific environments. The top-down approach starts from the statistical problem facing the (...) organism and a set of principles, such as the bias– variance tradeoff, that can explain when and why heuristics work in uncertain environments, and then shows how effective heuristics can be built by biasing and simplifying more complex models. We conclude with challenges these approaches face in developing a psychologically realistic perspective on human rationality. (shrink)

A way of reading the Tractatus has been proposed which, according to its advocates, is importantly novel and essentially distinct from anything to be found in the work of such previously influential students of the book as Anscombe, Stenius, Hacker or Pears. The point of difference is differently described, but the currently most used description seems to be Goldfarb’s term ‘resolution’ – hence one speaks of ‘the resolute reading’. I’ll shortly ask what resolution is. For now, it is enough that (...) it aims to give full weight to the penultimate section of the Tractatus in which Wittgenstein declares his propositions to be nonsense, where giving full weight to that declaration involves not hearing it as allowing that those ‘nonsensical’ propositions might have another kind of ‘sense’. In that same section Wittgenstein explains that these nonsense propositions, while devoid of meaning, have a use: to make the kind of use of them that their author intends – and so to understand him – requires recognizing that they are nonsense; and through that recognition one ‘surmounts’ these propositions, and is led ‘to see the world aright’. So there is a point to all this nonsense. What point? (shrink)

Moving beyond the traditional, and unproductive, rivalry between the fields of motivation and cognition, this book integrates the two domains to shed new light ...

It is sometimes argued that Wittgenstein's conception of grammar and the role he allocated to grammar (in his sense of the term) in philosophy changed between the Big Typescript and the Philosophical Investigations. It is also held that some of the grammatical propositions Wittgenstein asserted prior to his writing of the Philosophical Investigations are theses, doctrines, opinions or dogmatism, which he abandoned by 1936/37. The purpose of this paper is to show these claims to be misunderstandings and misinterpretations. On all (...) important matters, his conception of grammar and of grammatical investigations, of grammatical statements or propositions and of grammatical clarification did not change between the Big Typescript and the Investigations. Grammatical propositions (e.g. the meaning of a word is its use; a sample in an ostensive definition belongs to the means of representation; belief is not a mental state) are no more theses, doctrines or opinions than is “a bachelor is an unmarried man.” Nor are they in any way dogmatic. (shrink)

0. My aims in this paper are largely expository: I am more interested in presenting the picture theory than deciding its truth. Even so, I hope that the arguments by which I develop the theory will do something to support it, since I believe that what I will present as Wittgenstein's view is indeed the truth. This is not an admission of insanity, though some things that have been thought intrinsic to the picture theory are things it would be insane (...) to believe. So clearly the view I will present, when compared to the most embracing interpretations, is a partial and selective one. It would be another kind of madness, one I am just as eagre to disown, to suppose that my own favoured selection is the only possible one. That is pretty well the last remark in this paper about other commentators. I trust my reticence entitles me to be presumed catholic until proven nonconformist. (shrink)

Wittgenstein presents in the Tractatus a variable purporting to capture the general form of proposition. One understanding of what Wittgenstein is doing there, an understanding in line with the ‘new’ reading of his work championed by Diamond, Conant and others, sees it as a deflationary or even an implosive move—a move by which a concept sometimes put by philosophers to distinctively metaphysical use is replaced, in a perspicuous notation, by an innocent device of generalization, thereby dispersing the clouds of philosophy (...) that formerly surrounded the concept. By asking how Wittgenstein supposed his variable to work, and what work he imagined it was fit for, the paper questions the adequacy of that understanding. (shrink)

Wittgenstein, in the Tractatus, conceives the world as ‘the totality of facts’. Type-stratification threatens that conception : the totality of facts is an obvious example of an illegitimate totality. Wittgenstein’s notion of truthoperation evidently has some role to play in avoiding that threat, allowing propositions, and so facts, to constitute a single type. The paper seeks to explain that role in a way that integrates the ‘philosophical’ and ‘technical’ pressures on the notion of an operation.

Introduction Max Horkheimer was born on February in Stuttgart. By the time he died, on 7 July in Nuremberg, he had played a decisive role in launching and ...

We investigate how nonstandard reals can be established constructively as arbitrary infinite sequences of rationals, following the classical approach due to Schmieden and Laugwitz. In particular, a total standard part map into Richman's generalised Dedekind reals is constructed without countable choice.