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  1.  37
    Deliberately infecting healthy volunteers with malaria parasites: Perceptions and experiences of participants and other stakeholders in a Kenyan‐based malaria infection study.Irene Jao, Vicki Marsh, Primus Che Chi, Melissa Kapulu, Mainga Hamaluba, Sassy Molyneux, Philip Bejon & Dorcas Kamuya - 2020 - Bioethics 34 (8):819-832.
    Controlled human malaria infection (CHMI) studies involve the deliberate infection of healthy volunteers with malaria parasites under controlled conditions to study immune responses and/or test drug or vaccine efficacy. An empirical ethics study was embedded in a CHMI study at a Kenyan research programme to explore stakeholders’ perceptions and experiences of deliberate infection and moral implications of these. Data for this qualitative study were collected through focus group discussions, in‐depth interviews and non‐participant observation. Sixty‐nine participants were involved, including CHMI study (...)
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  2.  16
    Ethical considerations around volunteer payments in a malaria human infection study in Kenya: an embedded empirical ethics study.Dorcas Kamuya, Vicki Marsh, Melissa Kapulu, Philip Bejon, Irene Jao, Esther Awuor Owino & Primus Che Chi - 2022 - BMC Medical Ethics 23 (1):1-13.
    Human Infection Studies have emerged as an important research approach with the potential to fast track the global development of vaccines and treatments for infectious diseases, including in low resource settings. Given the high level of burdens involved in many HIS, particularly prolonged residency and biological sampling requirements, it can be challenging to identify levels of study payments that provide adequate compensation but avoid ‘undue’ levels of inducement to participate. Through this embedded ethics study, involving 97 healthy volunteers and other (...)
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  3.  44
    Feedback of Research Findings for Vaccine Trials: Experiences from Two Malaria Vaccine Trials Involving Healthy Children on the K enyan C oast.Caroline Gikonyo, Dorcas Kamuya, Bibi Mbete, Patricia Njuguna, Ally Olotu, Philip Bejon, Vicki Marsh & Sassy Molyneux - 2013 - Developing World Bioethics 13 (1):48-56.
    Internationally, calls for feedback of findings to be made an ‘ethical imperative’ or mandatory have been met with both strong support and opposition. Challenges include differences in issues by type of study and context, disentangling between aggregate and individual study results, and inadequate empirical evidence on which to draw. In this paper we present data from observations and interviews with key stakeholders involved in feeding back aggregate study findings for two Phase II malaria vaccine trials among children under the age (...)
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