Objective: To develop an approach for seeking informed consent to examine tissues retained from a previous study of sudden infant death syndrome as part of a study on asthma, and to document responses and participation rate.Design: Pilot open-ended approach to 10 volunteer SIDS parents, followed by staged approach to seek consent from the target SIDS families for the asthma study.Participants: Parents of SIDS infants known to SIDS and Kids Victoria and parents of SIDS infants from the 1991–2 SIDS in Victoria (...) case–control study.Main outcomes: Qualitative responses of the piloted parents and study parents, and participation rates.Results: The pilot group responses were used to refine the written material to be provided. Of the 72 families for which contact details were available, 45 gave verbal consent for contact by the Victorian Institute of Forensic Medicine regarding the asthma study, three refused and 24 did not respond to two letters. Thirty-three completed consent forms, all positive for participation in the asthma study, giving a positive response rate of 73% .Conclusions: The use of postmortem tissue for research is acceptable to the next of kin when an approach is sensitive to their concerns and needs and is made by experienced counsellors from a familiar organisation. Despite the painful memories evoked by the approach of the research group, the acceptance rate among those who could be contacted was high. (shrink)
Kasm does not offer any concept of proof which is regulative for all metaphysics, for he is convinced that each metaphysical approach requires its own proper logic and methodology. Within this pluralistic framework he seeks to discern the structure of formal truth as expressed in the concept of proof inherent in various metaphysical approaches.--L. S. F.
Remembered today primarily for his commentaries on Plato, R.L. Nettleship was a fellow and tutor of Balliol College, Oxford, from 1869 to 1892. And, while he was one of the past century’s better known interpreters of Plato, Nettleship’s influence extends well beyond the study of Greek philosophy. Although his life was cut short in its prime and saw the publication of no major works expressive of his own views, it is to Nettleship that we owe the existence of T.H. Green’s (...) collected Works and the book-length “Memoir” that introduces these volumes. And, despite its being ignored by later writers, Nettleship’s “Lectures on Logic” remains one of the most accessible accounts of the idealist theory of knowledge that came to dominate late nineteenth century British philosophy. (shrink)
Marriage patterns of California's eighteenth and nineteenth century Spanish-Mexican families are analysed using data from genealogies and mission records. A shortage of women among the military based colonists led to an unusual marriage pattern with a large age differential between husbands and wives. The average age at marriage was 18·4 years for women and 28·4 years for men. Spatial mobility was high for both sexes, particularly for men. More husbands than wives were born in Mexico. The Monterey presidial district of (...) central California was the birthplace of a disproportionate number of husbands and the southern California districts were a source of wives. The transition between a founding population predominantly composed of Mexican immigrants and a population of native-born Californians occurred at the beginning of the nineteenth century. (shrink)