This article discusses the Daoist contribution to the idea of human dignity in the classical Chinese philosophy, particularly in aspects that had been ignored by the Confucians and the Moists. By criticizing the traditional morality and reviving the faith in a primitive, self-sufficient life, Laozi and Zhuangzi add an important dimension to the classical understanding of human dignity: individual freedom, particularly the freedom of living under minimum burden, direction, and oppression of the state. By comparing the Daoist conception of human (...) dignity with those of the Confucians and Moists, the article concludes that all three classical schools, if rationally construed, should support the view that the establishment of a liberal constitutional scheme is necessary to preserve and protect minimum/basic dignity in both physical and spiritual well-being of every human person who lives in a modern society. (shrink)

“Beauty” is a very important concept in Pre-Qin Confucian aesthetics. Pre-Qin Confucian aesthetics generally had two viewpoints when defining beauty: Negatively, by stressing that “beauty” in the aesthetic sense was not “good”; and positively, by stressing two factors: one, that beauty was related to “feeling” which was not an animal instinct, the other was that “beauty” was a special texture with a particular meaning. “Beauty” in Pre-Qin Confucian aesthetics may be defined as “texture (or form)” capable of communicating feeling or (...) triggering a reaction of feeling. (shrink)

The human spindle and kinetochore associated complex is required for proper mitotic progression. Extensive studies have demonstrated its important functions in both stable kinetochore-microtubule interactions and spindle checkpoint silencing. We suggest a model to explain how various Ska functions might be fulfilled by distinct pools of Ska at kinetochores. The Ndc80-loop pool of Ska is recruited by the Ndc80 loop, or together with some of its flanking sequences, and the recruitment is also dependent on Cdk1-mediated Ska3 phosphorylation. This pool seems (...) to play a more important role in silencing the spindle checkpoint than stabilizing kinetochore-microtubule interactions. In contrast, the Ndc80-N-terminus pool of Ska is recruited by the N-terminal domains of Ndc80 and appears to be more important for stabilizing kinetochore-microtubule interactions. Here, we review and discuss the evidence that supports this model and suggest further experiments to test the functioning mechanisms of the Ska complex. The human spindle and kinetochore associated complex plays essential functions in proper mitotic progression by promoting stable kinetochore-microtubule interactions and spindle checkpoint silencing. We propose that “distinct pools” of Ska—the Ndc80-loop and Ndc80-N-terminus pools—might fulfill these various functions. (shrink)