6 found
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  1.  95
    Argumentation and Evidence.R. E. G. Upshur & Errol Colak - 2003 - Theoretical Medicine and Bioethics 24 (4):283-299.
    This essay explores the role of informal logicand its application in the context of currentdebates regarding evidence-based medicine. This aim is achieved through a discussion ofthe goals and objectives of evidence-basedmedicine and a review of the criticisms raisedagainst evidence-based medicine. Thecontributions to informal logic by StephenToulmin and Douglas Walton are explicated andtheir relevance for evidence-based medicine isdiscussed in relation to a common clinicalscenario: hypertension management. This essayconcludes with a discussion on the relationshipbetween clinical reasoning, rationality, andevidence. It is argued that (...)
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  2. The Virtues of Evidence.Erica Zarkovich & R. E. G. Upshur - 2002 - Theoretical Medicine and Bioethics 23 (4-5):403-412.
    Evidence-based medicine has beendefined as the conscientious and judicious useof current best evidence in making clinicaldecisions. This paper will attempt to explicatethe terms ``conscientious'''' and ``judicious''''within the evidence-based medicine definition.It will be argued that ``conscientious'''' and``judicious'''' represent virtue terms derived fromvirtue ethics and virtue epistemology. Theidentification of explicit virtue components inthe definition and therefore conception ofevidence-based medicine presents an importantstarting point in the connection between virtuetheories and medicine itself. In addition, aunification of virtue theories andevidence-based medicine will illustrate theneed for (...)
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  3.  78
    Priors and Prejudice.R. E. G. Upshur - 1999 - Theoretical Medicine and Bioethics 20 (4):319-327.
    This paper explores the relationship between concepts of probability and hermeneutics. It seeks to examine the relationship between subjective (Bayesian) views of probability and hermeneutic descriptions of understanding. It is argued that Gadamer'saccount of the prejudicial nature of understanding, derived from Heidegger'sanalysis of foreunderstanding, offers a provocative model of clinical reasoning. The implications of this model for evidence-based medicine are discussed in conclusion.
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  4.  83
    The Ethics of Alpha: Reflections on Statistics, Evidence and Values in Medicine.R. E. G. Upshur - 2001 - Theoretical Medicine and Bioethics 22 (6):565-576.
    As health care embraces the tenets of evidence-based medicine it is important to ask questions about how evidence is produced and interpreted. This essay explores normative dimensions of evidence production, particularly around issues of setting the tolerable level of uncertainty of results. Four specific aspects are explored: what health care providers know about statistics, why alpha levels have been set at 0.05, the role of randomization in the generation of sufficient grounds of belief, and the role of observational studies. The (...)
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  5.  9
    The Role of Faith-Based Organizations in the Ethical Aspects of Pandemic Flu Planning--Lessons Learned From the Toronto SARS Experience.H. S. Faust, C. M. Bensimon & R. E. G. Upshur - 2009 - Public Health Ethics 2 (1):105-112.
    Are restrictive measures and duties to care ethically reasonably acceptable to faith-based organizations? This study describes the perceptions of individually interviewed spiritual leaders of the disease control measures used during the recent SARS outbreak in Toronto. Four central themes were identified: the relationship between religious obligation and civic responsibilities; the role of faith-based organizations in supporting public health restrictive measures; the reciprocal obligations of public health and religious communities during restrictions; and justifiable limits to duties to care. We conclude that, (...)
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  6.  25
    Disability, Technology, and Place: Social and Ethical Implications of Long-Term Dependency on Medical Devices.B. E. Gibson, R. E. G. Upshur, N. L. Young & P. McKeever - 2007 - Ethics, Place and Environment 10 (1):7 – 28.
    Medical technologies and assistive devices such as ventilators and power wheelchairs are designed to sustain life and/or improve functionality but they can also contribute to stigmatization and social exclusion. In this paper, drawing from a study of ten men with Duchenne muscular dystrophy, we explore the complex social processes that mediate the lives of persons who are dependent on multiple medical and assistive technologies. In doing so we consider the embodied and emplaced nature of disability and how life is lived (...)
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