This article considers the ethics of photojournalism from a television news perspective. The author, on the basis of his participant?observation study conducted at two major?market television stations, suggests that while most of the television news photographers he observed and interviewed expressed strong ethical beliefs and values, those same individuals admitted they often acted in contradiction to many of their personal ethical beliefs. Their actions in carrying out their work and their revelations on the structure of their ethical beliefs indicate they (...) face a dilemma in balancing values. They must deal with the often contradictory values of competition, careerism, journalistic norms, peer pressure, technology, and management and organizational expectations. (shrink)

Background: Abortion policy varies significantly between Northern Ireland and Norway. This is the first study to compare medical students’ attitudes towards abortion in two different countries. Objective: To assess medical students’ attitudes to abortion at the University of Oslo (UiO) and Queen’s University Belfast (QUB). Design: An anonymous questionnaire completed by 59 medical students at UiO and 86 medical students at QUB. Participants: Students who had completed their obstetrics and gynaecology placements during 2006/2007. Results: The students’ responses (UiO versus QUB) (...) were as follows: response rate, 95.2% vs 92.5%; stated no religious affiliation, 48.0% vs 4.7%; pro-abortion, 78.2% vs 14.3% (χ2 = 58.160, p<0.001); had seen an abortion while studying medicine, 74.6% vs 9.4% (χ2 = 73.183, p<0.001); in favour of abortion when there was a threat to the mother’s life, 100% vs 93.3% (χ2 = 6.143, p = 0.150); in favour of providing abortion on the mother’s request, 86.4% vs 9.3% (χ2 = 42.067, p<0.001); in agreement that women should have access to free abortion services (mean value on a 5-point Likert scale 1.69 out of 5), versus in disagreement (mean 3.76, p<0.001). Conclusion: There were significant differences in students’ attitudes to abortion, reflecting differences in religious, legal and educational experiences. (shrink)

The mechanisms by which most receptor protein‐tyrosine kinases (RTKs) transmit signals are now well established. Binding of ligand results in the dimerization of receptor monomers followed by transphosphorylation of tyrosine residues within the cytoplasmic domains of the receptors. This tidy picture has, however, some strange characters lurking around the edges. Cases have now been identified in which RTKs lack kinase activity, but, despite being “dead” appear to have roles in signal transduction. Even stranger are the cases in which genes encoding (...) RTKs produce protein products consisting of only a portion of the kinase domain. At least one such “fractured” RTK appears to be involved in signal transduction. Here we describe how these strange molecules might function and discuss the questions associated with their evolution. BioEssays 23:69–76, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

:While standard meta-analysis pools the results from randomized trials that compare two treatments, network meta-analysis aggregates the results of randomized trials comparing a wider variety of treatment options. However, it is unclear whether the aggregation of effect estimates across heterogeneous populations will be consistent for a meaningful parameter when not all treatments are evaluated on each population. Drawing from counterfactual theory and the causal inference framework, we define the population of interest in a network meta-analysis and define the target parameter (...) under a series of nonparametric structural assumptions. This allows us to determine the requirements for identifiability of this parameter, enabling a description of the conditions under which network meta-analysis is appropriate and when it might mislead decision making. We then adapt several modeling strategies from the causal inference literature to obtain consistent estimation of the intervention-specific mean outcome and model-independent contrasts between treatments. Finally, we perform a reanalysis of a systematic review to compare the efficacy of antibiotics on suspected or confirmed methicillin-resistant Staphylococcus aureus in hospitalized patients. (shrink)