43 found
Order:
Disambiguations
Rachel A. Ankeny [42]Rachel Allyson Ankeny [3]
See also
Rachel Allyson Ankeny
University of Adelaide
  1. What’s so Special About Model Organisms?Rachel A. Ankeny & Sabina Leonelli - 2011 - Studies in History and Philosophy of Science Part A 42 (2):313-323.
    This paper aims to identify the key characteristics of model organisms that make them a specific type of model within the contemporary life sciences: in particular, we argue that the term “model organism” does not apply to all organisms used for the purposes of experimental research. We explore the differences between experimental and model organisms in terms of their material and epistemic features, and argue that it is essential to distinguish between their representational scope and representational target. We also examine (...)
    Direct download (4 more)  
     
    Export citation  
     
    Bookmark   44 citations  
  2.  33
    Repertoires: A Post-Kuhnian Perspective on Scientific Change and Collaborative Research.Rachel A. Ankeny & Sabina Leonelli - 2016 - Studies in History and Philosophy of Science Part A 60:18-28.
  3.  23
    The Ethos and Ethics of Translational Research.Jane Maienschein, Mary Sunderland, Rachel A. Ankeny & Jason Scott Robert - 2008 - American Journal of Bioethics 8 (3):43 – 51.
    Calls for the “translation” of research from bench to bedside are increasingly demanding. What is translation, and why does it matter? We sketch the recent history of outcome-oriented translational research in the United States, with a particular focus on the Roadmap Initiative of the National Institutes of Health (Bethesda, MD). Our main example of contemporary translational research is stem cell research, which has superseded genomics as the translational object of choice. We explore the nature of and obstacles to translational research (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   25 citations  
  4.  48
    Re-Thinking Organisms: The Impact of Databases on Model Organism Biology.Sabina Leonelli & Rachel A. Ankeny - 2012 - Studies in History and Philosophy of Science Part C 43 (1):29-36.
    Community databases have become crucial to the collection, ordering and retrieval of data gathered on model organisms, as well as to the ways in which these data are interpreted and used across a range of research contexts. This paper analyses the impact of community databases on research practices in model organism biology by focusing on the history and current use of four community databases: FlyBase, Mouse Genome Informatics, WormBase and The Arabidopsis Information Resource. We discuss the standards used by the (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   12 citations  
  5. Model Organisms as Models: Understanding the 'Lingua Franca' of the Human Genome Project.Rachel A. Ankeny - 2001 - Proceedings of the Philosophy of Science Association 2001 (3):S251-.
    Through an examination of the actual research strategies and assumptions underlying the Human Genome Project (HGP), it is argued that the epistemic basis of the initial model organism programs is not best understood as reasoning via causal analog models (CAMs). In order to answer a series of questions about what is being modeled and what claims about the models are warranted, a descriptive epistemological method is employed that uses historical techniques to develop detailed accounts which, in turn, help to reveal (...)
    Direct download (4 more)  
     
    Export citation  
     
    Bookmark   20 citations  
  6.  70
    Fashioning Descriptive Models in Biology: Of Worms and Wiring Diagrams.Rachel A. Ankeny - 2000 - Philosophy of Science 67 (3):272.
    The biological sciences have become increasingly reliant on so-called 'model organisms'. I argue that in this domain, the concept of a descriptive model is essential for understanding scientific practice. Using a case study, I show how such a model was formulated in a preexplanatory context for subsequent use as a prototype from which explanations ultimately may be generated both within the immediate domain of the original model and in additional, related domains. To develop this concept of a descriptive model, I (...)
    Direct download (6 more)  
     
    Export citation  
     
    Bookmark   20 citations  
  7.  66
    Narratives of 'Terminal Sedation', and the Importance of the Intention-Foresight Distinction in Palliative Care Practice.Charles D. Douglas, Ian H. Kerridge & Rachel A. Ankeny - 2013 - Bioethics 27 (1):1-11.
    The moral importance of the ‘intention–foresight’ distinction has long been a matter of philosophical controversy, particularly in the context of end-of-life care. Previous empirical research in Australia has suggested that general physicians and surgeons may use analgesic or sedative infusions with ambiguous intentions, their actions sometimes approximating ‘slow euthanasia’. In this paper, we report findings from a qualitative study of 18 Australian palliative care medical specialists, using in-depth interviews to address the use of sedation at the end of life. The (...)
    Direct download (8 more)  
     
    Export citation  
     
    Bookmark   5 citations  
  8.  9
    Model Organisms as Models: Understanding the 'Lingua Franca' of the Human Genome Project.Rachel A. Ankeny - 2001 - Philosophy of Science 68 (S3):S251-S261.
    Through an examination of the actual research strategies and assumptions underlying the Human Genome Project, it is argued that the epistemic basis of the initial model organism programs is not best understood as reasoning via causal analog models. In order to answer a series of questions about what is being modeled and what claims about the models are warranted, a descriptive epistemological method is employed that uses historical techniques to develop detailed accounts which, in turn, help to reveal forms of (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   16 citations  
  9.  21
    Historiographic Reflections on Model Organisms: Or How the Mureaucracy May Be Limiting Our Understanding of Contemporary Genetics and Genomics.Rachel A. Ankeny - 2010 - History and Philosophy of the Life Sciences 32 (1).
  10.  3
    Geneticization in MIM/OMIM®? Exploring Historic and Epistemic Drivers of Contemporary Understandings of Genetic Disease.Rachel A. Ankeny - 2017 - Journal of Medicine and Philosophy 42 (4):367-384.
    Prior to the genomic sequencing era, the bible for those working in clinical genetics was McKusick’s Mendelian Inheritance in Man, which appeared in multiple editions between the 1960s and the late 1990s. This catalogue was organized according to general patterns of inheritance and focused on phenotypes. Beginning in the mid-1980s, it was replaced by Online Mendelian Inheritance in Man, a continuously updated catalogue documenting molecular relationships between genetic variation and phenotypic expression. This paper explores this resource’s evolution with attention to (...)
    No categories
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  11.  17
    ‘Extreme’ Organisms and the Problem of Generalization: Interpreting the Krogh Principle.Sara Green, Michael R. Dietrich, Sabina Leonelli & Rachel A. Ankeny - 2018 - History and Philosophy of the Life Sciences 40 (4):65.
    Many biologists appeal to the so-called Krogh principle when justifying their choice of experimental organisms. The principle states that “for a large number of problems there will be some animal of choice, or a few such animals, on which it can be most conveniently studied”. Despite its popularity, the principle is often critiqued for implying unwarranted generalizations from optimal models. We argue that the Krogh principle should be interpreted in relation to the historical and scientific contexts in which it has (...)
    No categories
    Direct download (6 more)  
     
    Export citation  
     
    Bookmark  
  12.  54
    The Moral Status of Preferences for Directed Donation: Who Should Decide Who Gets Transplantable Organs?Rachel A. Ankeny - 2001 - Cambridge Quarterly of Healthcare Ethics 10 (4):387-398.
    Bioethics has entered a new era: as many commentators have noted, the familiar mantra of autonomy, beneficence, nonmaleficence, and justice has proven to be an overly simplistic framework for understanding problems that arise in modern medicine, particularly at the intersection of public policy and individual preferences. A tradition of liberal pluralism grounds respect for individual preferences and affirmation of competing conceptions of the good. But we struggle to maintain (or at times explicitly reject) this tradition in the face of individual (...)
    Direct download (8 more)  
     
    Export citation  
     
    Bookmark   8 citations  
  13.  21
    Double Meanings Will Not Save the Principle of Double Effect.Charles D. Douglas, Ian H. Kerridge & Rachel A. Ankeny - 2014 - Journal of Medicine and Philosophy 39 (3):304-316.
    In an article somewhat ironically entitled “Disambiguating Clinical Intentions,” Lynn Jansen promotes an idea that should be bewildering to anyone familiar with the literature on the intention/foresight distinction. According to Jansen, “intention” has two commonsense meanings, one of which is equivalent to “foresight.” Consequently, questions about intention are “infected” with ambiguity—people cannot tell what they mean and do not know how to answer them. This hypothesis is unsupported by evidence, but Jansen states it as if it were accepted fact. In (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  14.  10
    Making Organisms Model Human Behavior: Situated Models in North-American Alcohol Research, Since 1950.Rachel A. Ankeny, Sabina Leonelli, Nicole C. Nelson & Edmund Ramsden - 2014 - Science in Context 27 (3):485-509.
    No categories
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  15.  11
    Response to Open Peer Commentaries on “The Ethos and Ethics of Translational Research”.Jason Scott Robert, Mary Sunderland, Rachel A. Ankeny & Jane Maienschein - 2008 - American Journal of Bioethics 8 (3):1-3.
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   4 citations  
  16.  33
    Regulation of hESC Research in Australia: Promises and Pitfalls for Deliberative Democratic Approaches. [REVIEW]Susan Dodds & Rachel A. Ankeny - 2006 - Journal of Bioethical Inquiry 3 (1-2):95-107.
    This paper considers the legislative debates in Australia that led to the passage of the Research Involving Human Embryos Act (Cth 2002) and the Prohibition of Human Cloning Act (Cth 2002). In the first part of the paper, we discuss the debate surrounding the legislation with particular emphasis on the ways in which demands for public consultation, public debate and the education of Australians about the potential ethical and scientific impact of human embryonic stem cells (hESC) research were deployed, and (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   4 citations  
  17.  22
    Marvelling at the Marvel: The Supposed Conversion of A. D. Darbishire to Mendelism. [REVIEW]Rachel A. Ankeny - 2000 - Journal of the History of Biology 33 (2):315 - 347.
    The so-called "biometric-Mendelian controversy" has received much attention from science studies scholars. This paper focuses on one scientist involved in this debate, Arthur Dukinfield Darbishire, who performed a series of hybridization experiments with mice beginning in 1901. Previous historical work on Darbishire's experiments and his later attempt to reconcile Mendelian and biometric views describe Darbishire as eventually being "converted" to Mendelism. I provide a new analysis of this episode in the context of Darbishire's experimental results, his underlying epistemology, and his (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   6 citations  
  18. The Conqueror Worm: An Historical and Philosophical Examination of the Use of the Nematode Caenorhabditis Elegans as a Model Organism.Rachel Allyson Ankeny - 1997 - Dissertation, University of Pittsburgh
    This study focuses on the concept of a 'model organism' in the biomedical sciences through an historical and philosophical examination of research with the nematode Caenorhabditis elegans. I explore the choice of C. elegans in the mid-1960s, showing a rich context existed within which the organism was selected as the focus for a molecular biological research program, including an experimental life prior to Sydney Brenner's work. I argue that this choice can be seen as an obvious outcome of what was (...)
    No categories
     
    Export citation  
     
    Bookmark   3 citations  
  19.  80
    How History and Philosophy of Science and Medicine Could Save the Life of Bioethics.Rachel A. Ankeny - 2003 - Journal of Medicine and Philosophy 28 (1):115 – 125.
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  20.  17
    Detecting Themes and Variations: The Use of Cases in Developmental Biology.Rachel A. Ankeny - 2012 - Philosophy of Science 79 (5):644-654.
  21.  51
    The Scope of Public Discourse Surrounding Proposition 71: Looking Beyond the Moral Status of the Embryo. [REVIEW]Tamra Lysaght, Rachel A. Ankeny & Ian Kerridge - 2006 - Journal of Bioethical Inquiry 3 (1-2):109-119.
    Human embryonic stem cell research has generated considerable discussion and debate in bioethics. Bioethical discourse tends to focus on the moral status of the embryo as the central issue, however, and it is unclear how much this reflects broader community values and beliefs related to stem cell research. This paper presents the results of a study which aims to identify and classify the issues and arguments that have arisen in public discourse associated with one prominent policy episode in the United (...)
    Direct download (4 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  22.  34
    A View of Bioethics From Down Under.Rachel A. Ankeny - 2003 - Cambridge Quarterly of Healthcare Ethics 12 (3):242-246.
    When I immigrated to Australia from the United States a few years ago, at first I found many similarities between the countries. But underneath the apparent similarities, notably a shared language, lay much deeper differences in history, politics, and culture that have considerable impacts on attitudes and approaches to issues in bioethics and medicine. For instance, debates continue regarding cloning and embryonic stem cell research, particularly given the long history of research in reproductive medicine and reproductive technologies in Australia. Although (...)
    Direct download (9 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  23.  20
    On Not Taking Objective Risk Assessments at Face Value.Rachel A. Ankeny & Ian Kerridge - 2004 - American Journal of Bioethics 4 (3):35 – 37.
    Direct download (4 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  24.  31
    Akira Akabayashi, MD, Ph. D., is Professor in the Department of Biomedical Ethics at the School of Health Science and Nursing, University of Tokyo Graduate School of Medicine, Tokyo, Japan, and Professor at the School of Public Health, Kyoto University Graduate School of Medicine, Kyoto, Japan. [REVIEW]Rachel A. Ankeny, M. L. S. Bette Anton, Ana Borovecki, Alister Browne, Debora Diniz, Elisa J. Gordon, Matti Häyry & Steve Heilig - 2004 - Cambridge Quarterly of Healthcare Ethics 13:215-217.
    Direct download  
     
    Export citation  
     
    Bookmark  
  25.  13
    Recasting the Debate on Multiple Listing for Transplantation Through Consideration of Both Principles and Practice.Rachel A. Ankeny - 1999 - Cambridge Quarterly of Healthcare Ethics 8 (3):330-339.
    Debates continue to surround the system in the United States for allocating transplantable cadaveric organs, due in large part to the scarcity of such organs in relation to the number of individuals waiting to undergo transplantation. Candidates awaiting transplantation gain access to cadaveric organs by being placed by individual transplant programs on the national list of the Organ Procurement and Transplantation Network, overseen by the United Network for Organ Sharing. In recent years, the UNOS board has visited the issue of (...)
    Direct download (6 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  26.  5
    No Real Categories, Only Chimeras and Illusions: The Interplay Between Morality and Science in Debates Over Embryonic Chimeras.Rachel A. Ankeny - 2003 - American Journal of Bioethics 3 (3):31-33.
    Direct download (4 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  27.  2
    The Bermuda Triangle: The Pragmatics, Policies, and Principles for Data Sharing in the History of the Human Genome Project.Kathryn Maxson Jones, Rachel A. Ankeny & Robert Cook-Deegan - 2018 - Journal of the History of Biology 51 (4):693-805.
    The Bermuda Principles for DNA sequence data sharing are an enduring legacy of the Human Genome Project. They were adopted by the HGP at a strategy meeting in Bermuda in February of 1996 and implemented in formal policies by early 1998, mandating daily release of HGP-funded DNA sequences into the public domain. The idea of daily sharing, we argue, emanated directly from strategies for large, goal-directed molecular biology projects first tested within the “community” of C. elegans researchers, and were introduced (...)
    Direct download (2 more)  
    Translate
     
     
    Export citation  
     
    Bookmark  
  28.  26
    The Overlooked Role of Cases in Casual Attribution in Medicine.Rachel A. Ankeny - 2014 - Philosophy of Science 81 (5):999-1011.
    Although cases are central to the epistemic practices utilized within clinical medicine, they appear to be limited in their ability to provide evidence about causal relations because they provide detailed accounts of particular patients without explicit filtering of those attributes most likely to be relevant for explaining the phenomena observed. This paper uses a series of recent case reports to explore the role of cases in casual attribution in medical diagnosis. It is argued that cases are brought together by practitioners (...)
    No categories
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark  
  29.  13
    Alexandra Minna Stern. Telling Genes: The Story of Genetic Counseling in America. Ix + 238 Pp., Apps., Bibl., Index. Baltimore: Johns Hopkins University Press, 2012. $60. [REVIEW]Rachel A. Ankeny - 2015 - Isis 106 (1):217-218.
    No categories
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  30.  20
    Akira Akabayashi, MD, Ph. D., is Professor in the Department of Biomedical Ethics at the School of Health Science and Nursing at the University of Tokyo Graduate School of Medicine, Tokyo, Japan, and Professor at the School of Public Health, Kyoto University Graduate School of Medicine, Kyoto, Japan. [REVIEW]Rachel A. Ankeny, M. L. S. Bette Anton, Alister Browne, Nuket Buken, Murat Civaner, Arthur R. Derse, Brent Dickson, Dan Eastwood, Todd Gilmer & Michael L. Gross - 2003 - Cambridge Quarterly of Healthcare Ethics 12:229-231.
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark  
  31.  22
    Bioethics Authorship in Context: How Trends in Biomedicine Challenge Bioethics.Rachel A. Ankeny & Sabina Leonelli - 2011 - American Journal of Bioethics 11 (10):22 - 24.
    The American Journal of Bioethics, Volume 11, Issue 10, Page 22-24, October 2011.
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  32.  12
    Back to Basics for Bioethics.Rachel A. Ankeny - 2003 - Metascience 12 (2):177-182.
    Direct download (6 more)  
     
    Export citation  
     
    Bookmark  
  33.  9
    Cloning Around (Survey Review of Books on Cloning).Rachel Allyson Ankeny - 2001 - Metascience 10 (3):401-405.
    Direct download  
     
    Export citation  
     
    Bookmark  
  34.  19
    Dealing Drugs with the Bush.Rachel A. Ankeny - 2004 - Cambridge Quarterly of Healthcare Ethics 13 (3):241-244.
    The past year in bioethics in Australia has been relatively predictable. We continue to struggle with rising healthcare costs, though thankfully not on par with numerous other countries due to a relatively positive economic outlook. We are still fighting difficulties associated with higher medical indemnity costs, which have again caused many physicians to leave private practice, particularly in high-risk and specialty practice areas. In response, the federal government delayed the imposition of the medical indemnity levy for physicians until mid 2005. (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark  
  35. Piecing Together the Mosaic of Virus History (Book Review of Angela NH Creager, The Life of a Virus: Tobacco Mosaic Virus as an Esperimental Model, 1930-1965). [REVIEW]Rachel Allyson Ankeny - 2003 - Metascience 12 (3):341-344.
     
    Export citation  
     
    Bookmark  
  36.  17
    Angela N.H. Creager,The Life of a Virus: Tobacco Mosaic Virus as an Experimental Model, 1930–1965. Chicago: University of Chicago Press, 2002. [REVIEW]Rachel A. Ankeny - 2003 - Metascience 12 (3):341-344.
    Direct download (6 more)  
     
    Export citation  
     
    Bookmark  
  37.  7
    “If We're Happy to Eat It, Why Wouldn't We Be Happy to Give It to Our Children?” Articulating the Complexities Underlying Women's Ethical Views on Genetically Modified Food.Rachel A. Ankeny & Heather J. Bray - 2016 - Ijfab: International Journal of Feminist Approaches to Bioethics 9 (1):166-191.
    I’m sick of being treated like a dumb Mum who doesn’t understand the science. As far as I’m concerned, my family’s health is just too important. … If the government can’t protect the safety of my family, then I will.Recent Greenpeace activism in Australia resulted in the destruction of a field trial of a line of wheat “designed” to improve human nutrition. This incident demonstrates that, while there is significant ongoing public and private investment in genetically modified crop research and (...)
    Direct download (4 more)  
     
    Export citation  
     
    Bookmark  
  38.  4
    Inviting Everyone to the Table: Strategies for More Effective and Legitimate Food Policy Via Deliberative Approaches.Rachel A. Ankeny - 2016 - Journal of Social Philosophy 47 (1):10-24.
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark  
  39.  1
    Catherine Waldby;, Robert Mitchell. Tissue Economies: Blood, Organs, and Cell Lines in Late Capitalism. Viii + 232 Pp., Apps., Bibl., Index. Durham, N.C.: Duke University Press, 2006. $74.95. [REVIEW]Rachel A. Ankeny - 2007 - Isis 98 (2):432-433.
    No categories
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  40. Individual Responsibility and Reproduction.Rachel A. Ankeny - 2007 - In Rosamond Rhodes, Leslie Francis & Anita Silvers (eds.), The Blackwell Guide to Medical Ethics. Blackwell.
  41. Matthew Smith. Another Person’s Poison: A History of Food Allergy. Xii + 290 Pp., Bibl., Index. New York: Columbia University Press, 2015. $29.95. [REVIEW]Rachel A. Ankeny - 2016 - Isis 107 (4):888-889.
    No categories
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  42. Philosophy of Biology, Psychology, and Neuroscience-The Organism in Philosophical Focus-Fashioning Descriptive Models in Biology: Of Worms and Wiring Diagrams.Manfred D. Laubichier & Rachel A. Ankeny - 2000 - Philosophy of Science 67 (3).
     
    Export citation  
     
    Bookmark  
  43.  56
    The Ethics of Inheritable Genetic Modification: A Dividing Line?John E. J. Rasko, Gabrielle O'Sullivan & Rachel A. Ankeny (eds.) - 2006 - Cambridge University Press.
    Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine, public health and biomedical ethics, have established a distinguished team of scientists and scholars to address the issues from the perspectives of biological and social science, law and ethics, including an intriguing Foreword from Peter Singer. Their purpose is to consider how society might deal with the ethical concerns raised by inheritable genetic modification, and to re-examine prevailing views about whether (...)
    Direct download  
     
    Export citation  
     
    Bookmark