The UK Human Fertilisation and Embryology Authority was right to permit tissue typing preimplantation genetic diagnosisOn July 21 2004, the Human Fertilisation and Embryology Authority , Britain’s regulatory agency for reproductive technologies, revised its policy on preimplantation genetic diagnosis for tissue typing.1,2 The authority of the HFEA to enact such a policy was affirmed by the UK’s highest court, the House of Lords, on April 28 2005.3 Preimplantation genetic diagnosis combines in vitro fertilisation with genetic testing. In PGD, embryos generally (...) undergo biopsy prior to the eight cell stage, followed by genetic testing for a particular trait. Tissue typing PGD is done to identify an embryo that is tissue matched for a child suffering from a severe disease requiring bone marrow or cord blood stem cell transplantation and for whom no living donor exists. This procedure was first performed in 2000.4 Precise matching of tissue types is critical to successful tissue transplant, and the donors of such tissues are often referred to as “saviour siblings”.Where a tissue matched individual already exists, extracting bone marrow from that individual or collecting cord blood already in storage, rather than creating a match, presents the most immediate treatment alternative. Bone marrow donation from adults or other medically competent individuals is not generally ethically contested, and bone marrow donation from medically incompetent individuals is also permissible under certain conditions.5 Where no living tissue donor exists, however, intentionally creating a donor through tissue typing PGD is among a short list of possible treatment options.The July HFEA policy change makes PGD licensable in cases where tissue typing is the only purpose of testing. Previously, PGD was licensable in the UK only for disease testing, and tissue typing PGD was permissible only when …. (shrink)

Festschrift in honor of 60th birthday of Āgamānaṅdasvāmikaḷ, 1896-1961; collection of his speeches and writings on Vedanta and other aspects of Hindu philosophy.

Articles on the relevance of Islam and a comparative look with European philosophy in the contemporary world.

Biography of Jiddu Krishnamurti, 1895-1986, Indian philosopher.

A Ramsey statement denoted \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${n \longrightarrow (k)^2_2}$$\end{document} says that every undirected graph on n vertices contains either a clique or an independent set of size k. Any such valid statement can be encoded into a valid DNF formula RAM(n, k) of size O(nk) and with terms of size \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\left(\begin{smallmatrix}k\\2\end{smallmatrix}\right)}$$\end{document}. Let rk be the minimal n for which the statement holds. We prove that (...) RAM(rk, k) requires exponential size constant depth Frege systems, answering a problem of Krishnamurthy and Moll [15]. As a consequence of Pudlák’s work in bounded arithmetic [19] it is known that there are quasi-polynomial size constant depth Frege proofs of RAM(4k, k), but the proof complexity of these formulas in resolution R or in its extension R(log) is unknown. We define two relativizations of the Ramsey statement that still have quasi-polynomial size constant depth Frege proofs but for which we establish exponential lower bound for R. (shrink)

First-2d ed. published under title: Manual de introduccion a la ciencia del derecho.

This book focuses on Andrew Arato’s democratic theory and its relevance to contemporary issues such as processes of democratization, civil society, constitution-making, and the modern Executive. Andrew Arato is -both globally and disciplinarily- a prominent thinker in the fields of democratic theory, constitutional law, and comparative politics, influencing several generations of scholars. This is the first volume to systematically address his democratic theory. Including contributions from leading scholars such as Dick Howard, Ulrich Preuss, Hubertus Buchstein, Janos Kis, Uri Ram, Leonardo (...) Avritzer, Carlos de la Torre, and Nicolás Lynch, this book is organized around three major areas of Arato´s influence on contemporary political and social thought. The first section offers a comprehensive view of Arato’s scholarship from his early work on critical theory and Western Marxism to his current research on constitution-making and its application. The second section shifts its focus from the previous, comprehensive approach, to a much more specific one: Arato´s widespread influence on the study of civil society in democratization processes in Latin America. The third section includes a previously unpublished work, ‘A conceptual history of dictatorship (and its rivals,)’ one of the few systematic interrogations on the meaning of a political form of fundamental relevance in the contemporary world. Critical Theory and Democracy will be of interest to critical and social theorists, and all Arato scholars. (shrink)

Contributed articles on Jacques Derrida, French philosopher, and his theories of deconstruction and postmoderinsm; includes articles on his perpectives on literature and philosophy.

Philosophical aspects of belief and ancestor worship in Southern Vietnam.

History of civilization and human nature of Vietnam.

Study on the contributions of Śaṅkarācārya to Hindu philosophy.

В издании подробно исследуется философское наследие четырех учителей дигамбарской ветви джайнизма.

Author's answers to questions on Buddhist philosophy, posed to him by some foreign scholars.

I develop and test a multilevel trust-based model of ethical public leadership, which links ethical leadership, trust and leadership outcomes both within and across organizational levels. I examine how both ethical leadership and trust relate to employee well-being and satisfaction, group organizational citizenship behaviour and perceived organizational performance. The findings, based on data collected from an online quantitative survey conducted in three local councils of the north east of England, provide evidence in support of positive relationships between ethical leadership and (...) employees’ trust in leaders at multiple levels. This trust is in turn shown to influence employees’ attitudes, behaviours and cognitions. (shrink)