PURPOSE: There is an increasing demand for researchers to provide research results to participants. Our aim was to define an appropriate process for this, based on needs and attitudes of participants. METHODS: A multicenter survey in five sites in the United States and Canada was offered to parents of children with cancer and adolescents with cancer. Respondents indicated their preferred mode of communication of research results with respect to implications; timing, provider, and content of the results; reasons for and against (...) providing results; and barriers to providing results. RESULTS: Four hundred nine parents (including 19 of deceased children) and 86 adolescents responded. Most parents (n = 385; 94.2%) felt that they had a strong right to research results. For positive results, most wanted a letter or e-mail summary (n = 238; 58.2%) or a phone call followed by a letter (n = 100; 24.4%). If the results were negative, phone call (n = 136; 33.3%) or personal visits (n = 150; 36.7%) were preferred. Parents wanted the summary to include long-term sequelae and suggestions for participants (n = 341; 83.4%), effect on future treatments (n = 341; 83.4%), and subsequent research steps (n = 284; 69.5%). Understanding the researcher was a main concern about receiving results (n = 145; 35.5%). Parents felt that results provide information to support quality of life (n = 315; 77%) and raise public awareness of research (n = 282; 68.9%). Adolescents identified similar preferences. CONCLUSION: Parents of children with cancer and adolescents with cancer feel strongly that they have a right to be offered research results and have specific preferences of how and what information should be communicated. (shrink)

Background: Low rates of participation of adolescents and young adults (AYAs) in clinical oncology trials may contribute to poorer outcomes. Factors that influence the decision of AYAs to participate in health research and whether these factors are different from those that affect the participation of parents of children with cancer. Methods: This is a secondary analysis of data from validated questionnaires provided to adolescents (>12 years old) diagnosed with cancer and parents of children with cancer at 3 sites in Canada (...) (Halifax, Vancouver, and Montreal) and 2 in the United States (Atlanta, GA, and Memphis, TN). Respondents reported their own research participation and cited factors that would influence their own decision to participate in, or to provide parental authorization for their child to participate in health research. Results: Completed questionnaire rates for AYAs and parents were 86 (46.5%) of 185 and 409 (65.2%) of 627, respectively. AYAs (n = 86 [67%]) and parents (n = 409 [85%]) cited that they would participate in research because it would help others. AYAs perceived pressure by their family and friends (16%) and their physician (19%). Having too much to think about at the time of accrual was an impediment to both groups (36% AYAs and 47% parents). The main deterrent for AYAs was that research would take up too much time (45%). Nonwhite parents (7 of 56 [12.5%]) were more apt to decline than white parents (12 of 32 [3.7%]; P < .01). Conclusions: AYAs identified time commitment and having too much to think about as significant impediments to research participation. Addressing these barriers by minimizing time requirements and further supporting decision-making may improve informed consent and impact on enrollment in trials. (shrink)

This book explores the pervasiveness of poetry's impact on philosophy and, conversely, how philosophy has sometimes resisted or denied poetry's influence.

ABSTRACT Objective: To identify perceived barriers to capacity building for local research ethics oversight in El Salvador, and to set an agenda for international collaborative capacity building. Methods: Focus groups were formed in El Salvador which included 17 local clinical investigators and members of newly formed research ethics committees. Information about the proposed research was presented to participants during an international bioethics colloquium sponsored and organized by the St. Jude Children's Research Hospital in collaboration with the National Ethics Committee of (...) El Salvador and the University of El Salvador. Interviews with the focus group participants were qualitatively analyzed. Results: Participants expressed the need to tailor the informed consent process and documentation to the local culture; for example, allowing family members to participate in decision‐making, and employing shorter consent forms. Participants indicated that economic barriers often impede efforts in local capacity building. Participants valued international collaboration for mutual capacity building in research ethics oversight. Conclusions: Research ethics committees in El Salvador possess a basic knowledge of locally relevant ethical principles, though they need more training to optimize the application of bioethical principles and models to their particular contexts. Challenges increase the value of collaborative exchanges with ethics committee members in the United States. Further research on facilitating communication between host country and sponsor country ethics committees can maximize local research ethics expertise, and thus raise the standard of protecting human participants involved in international research. (shrink)

The specification and implementation of computational artefacts occurs throughout the discipline of computer science. Consequently, unpacking its nature should constitute one of the core areas of the philosophy of computer science. This paper presents a conceptual analysis of the central role of specification in the discipline.

Cet ouvrage est une réédition numérique d’un livre paru au XXe siècle, désormais indisponible dans son format d’origine.

Its first paradigms are in the writings of Marx and Freud. In this book Raymond Geuss sets out these fundamental claims and asks whether they can be made good.

This book addresses critical issues in normative ethical theory. Every such theory must contain not only a theory of motivation but also a theory of value, and the link that is often forged between what is valuable and what would be right is human welfare or well-being. This topic is a subject of considerable controversy in contemporary ethics, not least because of the current reconsideration of utilitarianism. Indeed, there is as much disagreement about the nature of value and its relationship (...) to welfare and morality, as there is about the substantive content of normative ethical theories. The essays in this collection, all written by a distinguished team of moral philosophers, provide an overview, analysis and an attempted resolution of those controversies. They constitute a rigorous account of the relationships among value, welfare and morality. (shrink)

A fundamental question in philosophy of religion is whether religious belief must be based on evidence in order to be properly held. In recent years two prominent positions on this issue have been staked out: evidentialism, which claims that proper religious belief requires evidence; and Reformed epistemology, which claims that it does not. Evidence and Religious Belief contains eleven chapters by prominent philosophers which push the discussion in new directions. The volume has three parts. The first part explores the demand (...) for evidence: some chapters object to it while others seek to restate it or find space for compromise between Reformed epistemology and evidentialism. The second part explores ways in which beliefs are related to evidence; that is, ways in which the evidence for or against religious belief that is available to a person can depend on that person's background beliefs and other circumstances. The third part contains chapters that discuss actual evidence for and against religious belief. Evidence for belief in God includes the so-called common consent of the human race and the way that such belief makes sense of the moral life; evidence against it includes profound puzzles about divine freedom which suggest that it is impossible for a being to be morally perfect. (shrink)

There has been much debate recently about the meaning, place and function of “character” and “character traits” in Virtue Ethics. For example, a number of philosophers have argued recently that Virtue Ethics would be strengthened as a theory by the omission of talk of character traits; recent neuroscientific studies have suggested that there is scope for scepticism about the existence of such traits. I will argue that both approaches are flawed and unconvincing: in brief, the first approach tends to be (...) predicated on a narrow or insufficient conception of “character” and “character traits”; the second approach tends to go well beyond the available (empirical) evidence. Finally, I will argue that it is possible to point to a philosophy of education that is deeply informed by an understanding of virtue and ethics in which the concept of character has a coherent and meaningful role. (shrink)

AbstractWhat explains followers’ attraction to tyrannical leaders? They systematically coerce, belittle, and manipulate, often at the expense of subordinates’ mental and physical well-being and their organization’s long-term interests. To help address the question, we examine the tendencies of people who view the tyrannical leader prototype (characterized by domineering, pushy, manipulative, loud, conceited, and selfish traits) as a component of effective leadership (Epitropaki and Martin in J Appl Psychol 89:293–310, 2004; Foti et al. in Leadersh Q 23:702–717, 2012). Specifically, we apply (...) moral and evolutionary psychology to propose and empirically test a mediation model in which belief in a dangerous world (Altemeyer in Enemies of freedom: understanding right-wing authoritarianism. Jossey-Bass, San Francisco, 1988) links positively with endorsement of the tyrannical leader traits, as mediated through the binding components (loyalty, authority, and sanctity) of moral foundations theory (Graham et al. J Pers Soc Psychol 101:366–385, 2011). Regarding gender, our model proposes that the link between the binding foundations and tyrannical leadership endorsement is stronger among males than females. Our overall model was supported across two independent samples of working adults; we also anticipated and found a direct negative association between the individualizing moral foundations (care and harm) and endorsement of the tyrannical prototype. These findings provide insights into the circumstances under which tyrannical traits are viewed as part of effective leadership. (shrink)

(1997). The anticipation of order in biosocial collectives. World Futures: Vol. 49, The Dialatic of Evolution: Essays in Honor of David Loye, pp. 65-88.

This book details the results of the authors' research using laboratory animals to investigate individual choice theory in economics-consumer-demand and labour supply behaviour and choice under uncertainty. The use of laboratory animals provides the opportunity to conduct controlled experiments involving precise and demanding tests of economic theory with rewards and punishments of real consequence. Economic models are compared to psychological and biological choice models along with the results of experiments testing between these competing explanations. Results of animal experiments are used (...) to address questions of social policy importance. (shrink)

Many things in the natural world work so well that they seem to have been designed. But by what? Could nature itself, by processes including those of evolution, be the designer? Or must their complex structure and function be attributed to some intelligent designer or God? Is natural design compatible with intelligent design? How good is the argument from the presence of design to an intelligent designer? And if we could legitimately infer the probable existence of an intelligent designer from (...) the presence of design in the natural world, what could we then infer about that designer's nature? (shrink)

This article presents Epistemic Spatialization as a new framework for investigating the interconnected patterns of biases when identifying objects with convolutional neural networks (convnets). It draws upon Foucault’s notion of spatialized knowledge to guide its method of enquiry. We argue that decisions involved in the creation of algorithms, alongside the labeling, ordering, presentation, and commercial prioritization of objects, together create a distorted “nomination of the visible”: they harden the visibility of some objects, make other objects excessively visible, and consign yet (...) others to permanent or haphazard invisibility. Our approach differs from those who focus on high-stakes misidentifications, such as errors tied to structural racism. Examining the far more dominant series of low-stakes mistakes shows the scope of errors, destabilizing the goal of image content identification with considerable societal impact. We explore these issues by closely examining the demonstration video of a popular convnet. This examination reveals an interlocking series of biases undermining the content identification process. The picture we paint is crucial for a better understanding of the errors that result as these convnets become further embedded in everyday products. The framework is valuable for critical work on computer vision, AI studies, and large-scale visual analysis. (shrink)

The belief in fatalism, like many others, has its roots in the quasi-religious mythologies of ancient peoples many of whom personified the notion of fate. Thus Greek mythology supposed that three Fates, daughters of the goddess of Necessity, had control of our lives from beginning to end and that it was therefore impossible for us to do anything contrary to what they had prescribed for us. We may think we are in control of our own destinies. But we are mistaken. (...) Both Homer's Odysseus and Aeschelus's Prometheus Unbound, depict mortals as puppets of the gods. (shrink)

I come not to praise God but to bury him along with the dead gods of now forgotten religions. Not to praise him as the source of all that's good in the world, and hence the ultimate guide to human morals, but to indict him as the self-confessed source of all that's wrong with it. When the Christian God says in his Holy Scriptures, that he is the creator of evil, I am prepared to take him at his word.

In lieu of an abstract, here is a brief excerpt of the content:“Reason and Religion”: The Science of AnglicanismRaymond D. TumblesonThis essay explores a rhetoric of “reason” in Anglican anti-Catholic polemics during the short and turbulent reign of James II. This reign witnessed an intense propaganda battle between Catholic and Anglican pamphleteers because the former for the first time in over a century were permitted openly to put their case, and in response the latter defended their doctrine and status as (...) the established church with a new urgency. For the first time, the possibility, feared by English Protestants and hoped for by Catholics, that given encouragement many people would convert to Catholicism, “the most conspicuous deviant element in society,” seemed credible, although, unsurprisingly given the brevity of James’s rule, both hope and fear proved groundless. 1 In addition to reiterated claims to have scripture and antiquity on their side, apologists for the Church of England offered a third and clinching argument against Catholicism—that reason itself was with them. They saw no contradiction between what Richard Sherlock calls a “scripture-based argumentative framework” and “the priority of natural reason.” 2 In A Rational Account of the Grounds of Protestant Religion Edward Stillingfleet developed what would become the predominant Anglican theological case against Catholicism twenty years later, when he endorsed “the judgement of Sense” as the means to a “certainty “ independent of the Papal “Infallibility “ that “Destroy[s] the obligation to Faith which ariseth from the rational evidence of Christian Doctrine.” 3 Far from mutually [End Page 131] exclusive, Protestantism and reason seemed naturally complementary, even identical, to Anglican polemicists: only Popery, in its superstition, idolatry, and implicit faith, was antagonistic to reason. As Richard W. F. Kroll observes, the “defense of contingency, premised on a skeptical empiricism, becomes not the chief discourse of dissent but, again, its opposite: the language of the most visible institutions returned to power after the Restoration.” 4 Reason and the Anglican monopoly of worship are consistently identified by Anglican apologists of the 1680s, and Popery threatens both.What Terry Eagleton has called “the Enlightenment dream of a world entirely transparent to reason, free of the prejudice, superstition and ob-scurantism of the ancien regime” has unacknowledged antecedents in Protestant polemics against “the prejudice, superstition and obscurantism” of Catholicism. 5 This essay examines the differences between the polemical literatures of the reigns of Charles II and James II, the ways in which “reason” becomes an important force against Catholicism, and the method in which this usage entangles anti-Catholicism in the construction of modern science. In 1685, the year of James’s coronation, John Williams argued that religious services ought to be conducted “in a Tongue understood of the people,” recommending that “we consult the reason of the thing.” 6 In attacking Catholicism, Anglican theologians redefined religion itself as based more on reason than on faith, because Papists could lay equal claim to faith, but only the Church of England possessed reason as they defined it. Stillingfleet’s theological career is paradigmatic for Restoration Angli-canism’s enlistment of reason in sectarian disputes: his Originae Sacrae (1662) defends Christianity as rational, then in 1665 A Rational Account of the Grounds of Protestant Religion narrows religious rationality to exclude Catholicism; in the wake of the Exclusion Crisis, the 1681 The Unreasonableness of Separation chides Dissenters for being “unreasonable” because they do not conform to the Church of England; and finally in 1687 The Doctrine of the Trinity and Transubstantiation Compared, as to Scripture, Reason, and Tradition returns to the subject of A Rational Account, tightening its six hundred learned pages into colloquial propaganda aimed at lay readers. 7 In the clear light of reason, where the only static—in Michel [End Page 132] Serres’s sense—is corruption, disagreement (with Anglicanism) becomes impossible. 8This paper examines sectarian polemics in order to approach the relation between science, the paradigmatic modern intellectual structure, and theology, the paradigmatic premodern intellectual sructure, from an unaccustomed angle. The immense wave of propagandistic Anglican theologizing under James II establishes the superiority of the Church of England to Rome by re-borrowing the methods and conventions of rationality which scientific experimentalism itself had originally derived from theology. 9 In these tracts... (shrink)

A stimulating introduction to central issues of political theory, including liberty, rights and the state, and the claims of need and politics.

How to point : a primer for Martians -- What it takes to be a pointer -- Do animals get the point? -- People who don't point -- Pinning language to the world -- Pointing and power -- Assisted pointing and pointing by proxy -- The transcendent animal : pointing and the beyond.

This work subjects the fundamental ideas of Derrida, Lacan, Barthes and their followers to an examination and demonstrates the baselessness of post-Saussurean claims about the relations between language, reality and self.

Human bodies have a totally different mode of existence from those collections of mental properties (intelligence, will power, consciousness, etc.) that we call minds. They belong to the ontological category of physical substances or entities, whereas mental properties belong to the ontological category of properties or attributes, and as such can exist only so long as their physical bearers exist. Mental properties “emerge” (in a sense that makes emergence ubiquitous throughout the natural world) when the constituent parts of a biological (...) organism—especially its brain—are configured in certain sorts of ways. A view of reality that is both conceptually coherent and scientifically comprehensive makes the very idea of surviving one’s bodily death literally absurd. -/- 1. The Cheshire Cat Fallacy: “A Grin Without a Cat” -- 2. Two Main Arguments for Substance Dualism - 2.1 An Appeal to the Logic of Identity and Difference - 2.2 An Appeal to the Noncogitative Nature of Matter -- 3. A Host of Problems for Substance Dualism - 3.1 The Inexplicability of Mind-Brain Dependence - 3.2 The Inexplicability of Mental Causation - 3.3 The Violation of Scientific Laws - 3.4 Minds as Miracle-Workers - 3.5 Problems about Our Embryological and Developmental Histories - 3.6 Problems about our Evolutionary Histories - 3.7 Which Stage of the Soul or Mind Survives? - 3.8 Where are our Disembodied Souls Supposed to Survive? -- 4. The Argument from Leibniz’s Law Presupposes a Category Misallocation - 4.1 The Fallacy of Reification - 4.2 Resisting the Reifying Lure of Language - 4.3 Dualistic Consequences of Reifying Mentalistic Terms - 4.4 Allocation to Ontological Categories - 4.5 Locke’s Partial Solution to the Category Misallocation - 4.6 Ryle on Category Mistakes and “the Ghost in the Machine” - 4.7 Ryle’s Important Insight: To Have a Mind is to have a Set of Mental Properties - 4.8 Interim Summary -- 5. The Emergence of “Minds” from Incogitative Matter - 5.1 Locke’s A Priori Argument - 5.2 Locke’s Argument Refuted by Counterexamples - 5.3 The Concept of Emergence Defined - 5.4 Rival Concepts of Emergence - 5.5 The Ubiquitousness of Emergent Properties - 5.6 The Metaphysics of Emergent Materialism - 5.6.1 Substance Monism - 5.6.2 The Doctrine of Property Dualism is Misconceived - 5.6.3 Emergent Properties of Different Kinds - 5.6.4 The “Hierarchy” of Sciences - 5.6.5 The Broad Spectrum of “Mental” Properties -- 6. The Metaphysical Impossibility of Survival - 6.1 Mind-Brain Dependence - 6.2 The Issue of Mental Causation - 6.2.1 The Bogeyman of Epiphenomenalism - 6.3 The Violation of Scientific Laws - 6.4 Minds as Miracle-Workers - 6.5 Our Embryological and Developmental Histories - 6.6 Our Evolutionary Histories -- 7. Conclusion. (shrink)

Clear and helpful explanation of the details of each book in the Bible. Additional chapters provide background information to aid understanding. Ideal reference source for anyone studying or using the Bible.

The first weekly English newsbooks appeared in November 1641, on the eve of the civil war. Though they provoked animosity and fanned the flames of civil war, they have survived almost without interruption to the present day, transformed into the modern newspaper. The Invention of the Newspaper is the first detailed account of the origins and early development of the English newspaper, using a wealth of new evidence to show the causes of the first newsbooks, and their many and complex (...) roles in the turbulent society in which they participated.Newsbooks were widely read and exerted considerable influence not only over immediate perceptions of news, but also over subsequent histories of the seventeenth-century, extending even to the present day. Using and synthesising approaches from literary criticism, history, and the 'socoiology of texts', The Invention of the Newspaper shows how newsbooks transformed print culture, fed the public hunger for news, and in turn created a market for news periodical. Charting the newsbook's development as a form and a commercial enterprise, its literary qualities, and its relationship to other means of communication, The Invention of the Newspaper shows the newsbook's gradual and irresistible dominance of the market for information. (shrink)

Facing up to the head -- The secreting head -- Being my head -- The head comes to -- Airhead : breathing and its variations -- Communicating with air -- Enjoying and suffering my head -- Communicating without air -- Notes on the red-cheeked animal : the geology of a blush -- The watchtower -- The sensory room -- Having and using my head -- Head traffic : eating, vomiting and smoking -- Head on head : notes on kissing -- (...) Headgear -- Caretaking my head -- In the wars -- The dwindles -- Knowing (and not knowing) my head -- Head and world -- The thinking head -- Epilogue: Heading off. (shrink)

Knowledge intellectualism is the view that knowledge-how requires propositional knowledge. Knowledge intellectualism has a Gettier problem, or so many of its critics allege. The essence of this problem is that knowledge-how is compatible with epistemic luck in a way that ordinary propositional knowledge is not. Hence, knowledge-how can allegedly be had in the absence of knowledge-that, a fact inconsistent with knowledge intellectualism. -/- This paper develops two responses to this challenge to knowledge intellectualism. First, it is not clear that propositional (...) knowledge is incompatible with the forms of epistemic luck with which knowledge-how is allegedly compatible. Second, existing cases intended to serve as counterexamples to knowledge intellectualism are flawed, and revised versions of these cases no longer elicit the judgments necessary to challenge knowledge intellectualism. (shrink)

This paper contends that the concept of the autobiography in the essayist tradition, most prominent in the Essays of Montaigne, has the capacity to powerfully renew a philosopher’s understanding of the constantly changing self. This is possible not only due to the characteristics of Montaigne’s style such as his skepticism, his relativism, but his experience of his weaknesses and circumstances as common conditions of universal humanity. As a totality, these guide him towards a philosophical understanding of the mystery that is (...) the “miracle” of the self. The objective, process and result of Montaigne’s Essays, is a heightened understanding of himself by examining, as closely and frankly as possible, his own unique condition, which also happens to be shared by common humanity. The subsequent examinations on the self renew themselves constantly, for there is a focal point of universal reference. This paper brings together specific techniques of Montaigne’s stylistic discourse and ideas on various subjects that all renew, in part, his understanding of his mysterious self. This paper is aimed at a general audience that may not have enjoyed full exposure to the vast compendium of Montaigne literature, and is offered in the hope of contributing to the process of understanding how the autobiographical essay renews a successful meditation on one’s self and vocation to humanity. (shrink)