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Rebecca L. Walker [24]Rebecca Louise Walker [1]
  1.  12
    Looking for Trouble: Preventive Genomic Sequencing in the General Population and the Role of Patient Choice.Gabriel Lázaro-Muñoz, John M. Conley, Arlene M. Davis, Marcia Van Riper, Rebecca L. Walker & Eric T. Juengst - 2015 - American Journal of Bioethics 15 (7):3-14.
    Advances in genomics have led to calls for developing population-based preventive genomic sequencing programs with the goal of identifying genetic health risks in adults without known risk factors. One critical issue for minimizing the harms and maximizing the benefits of PGS is determining the kind and degree of control individuals should have over the generation, use, and handling of their genomic information. In this article we examine whether PGS programs should offer individuals the opportunity to selectively opt out of the (...)
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  2.  18
    Serial Participation and the Ethics of Phase 1 Healthy Volunteer Research.Rebecca L. Walker, Marci D. Cottingham & Jill A. Fisher - 2018 - Journal of Medicine and Philosophy 43 (1):83-114.
    Phase 1 healthy volunteer clinical trials—which financially compensate subjects in tests of drug toxicity levels and side effects—appear to place pressure on each joint of the moral framework justifying research. In this article, we review concerns about phase 1 trials as they have been framed in the bioethics literature, including undue inducement and coercion, unjust exploitation, and worries about compromised data validity. We then revisit these concerns in light of the lived experiences of serial participants who are income-dependent on phase (...)
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  3. Working Virtue: Virtue Ethics and Contemporary Moral Problems.Rebecca L. Walker & Philip J. Ivanhoe (eds.) - 2006 - Oxford University Press.
    In Working Virtue: Virtue Ethics and Contemporary Moral Problems, leading figures in the fields of virtue ethics and ethics come together to present the first ...
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  4. Working Virtue. Virtue Ethics and Contemporary Moral Problems.Rebecca L. Walker & Philip J. Ivanhoe - 2007 - Tijdschrift Voor Filosofie 69 (4):779-780.
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  5.  10
    The Ethics of General Population Preventive Genomic Sequencing: Rights and Social Justice.Clair Morrissey & Rebecca L. Walker - 2018 - Journal of Medicine and Philosophy 43 (1):22-43.
    Advances in DNA sequencing technology open new possibilities for public health genomics, especially in the form of general population preventive genomic sequencing. Such screening programs would sit at the intersection of public health and preventive health care, and thereby at once invite and resist the use of clinical ethics and public health ethics frameworks. Despite their differences, these ethics frameworks traditionally share a central concern for individual rights. We examine two putative individual rights—the right not to know, and the child’s (...)
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  6. Human and Animal Subjects of Research: The Moral Significance of Respect Versus Welfare.Rebecca L. Walker - 2006 - Theoretical Medicine and Bioethics 27 (4):305-331.
    Human beings with diminished decision-making capacities are usually thought to require greater protections from the potential harms of research than fully autonomous persons. Animal subjects of research receive lesser protections than any human beings regardless of decision-making capacity. Paradoxically, however, it is precisely animals’ lack of some characteristic human capacities that is commonly invoked to justify using them for human purposes. In other words, for humans lesser capacities correspond to greater protections but for animals the opposite is true. Without explicit (...)
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  7. Respect for Rational Autonomy.Rebecca L. Walker - 2009 - Kennedy Institute of Ethics Journal 19 (4):pp. 339-366.
  8.  11
    Virtue, Vice, and "Voracious" Science: How Should We Approach the Ethics of Primate Research?Rebecca L. Walker - 2018 - Perspectives in Biology and Medicine 61 (1):130-146.
    From the late 1950s through the early 1970s, Harry F. Harlow's primate laboratory at the University of Wisconsin–Madison undertook a series of studies on infant rhesus macaque monkeys that gained the attention of both animal welfare advocates and the scientific community.1 Establishing one of the first primate research laboratories in 1932, Harlow began his career as a primate researcher by studying primate learning capabilities and shredding previous assumptions within psychology that primates were restricted to the conditioned learning of a rat. (...)
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  9.  14
    Beyond Primates: Research Protections and Animal Moral Value.Rebecca L. Walker - 2016 - Hastings Center Report 46 (4):28-30.
    Should monkeys be used in painful and often deadly infectious disease research that may save many human lives? This is the challenging question that Anne Barnhill, Steven Joffe, and Franklin G. Miller take on in their carefully argued and compelling article “The Ethics of Infection Challenges in Primates.” The authors offer a nuanced and even-handed position that takes philosophical worries about nonhuman primate moral status seriously and still appreciates the very real value of such research for human welfare. Overall, they (...)
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  10.  45
    Bioethics Methods in the Ethical, Legal, and Social Implications of the Human Genome Project Literature.Rebecca L. Walker & Clair Morrissey - 2014 - Bioethics 28 (9):481-490.
    While bioethics as a field has concerned itself with methodological issues since the early years, there has been no systematic examination of how ethics is incorporated into research on the Ethical, Legal and Social Implications of the Human Genome Project. Yet ELSI research may bear a particular burden of investigating and substantiating its methods given public funding, an explicitly cross-disciplinary approach, and the perceived significance of adequate responsiveness to advances in genomics. We undertook a qualitative content analysis of a sample (...)
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  11.  3
    Genomic Research with the Newly Dead: A Crossroads for Ethics and Policy.Rebecca L. Walker, Eric T. Juengst, Warren Whipple & Arlene M. Davis - 2014 - Journal of Law, Medicine and Ethics 42 (2):220-231.
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  12. Introduction.Rebecca L. Walker & Philip J. Ivanhoe - 2007 - In Rebecca L. Walker & Philip J. Ivanhoe (eds.), Working Virtue: Virtue Ethics and Contemporary Moral Problems. Oxford University Press.
     
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  13.  5
    "My Body is One of the Best Commodities": Exploring the Ethics of Commodification in Phase I Healthy Volunteer Clinical Trials.Rebecca L. Walker & Jill A. Fisher - 2020 - Kennedy Institute of Ethics Journal 29 (4):305-331.
    In phase I clinical trials, healthy volunteers are dosed with investigational drugs and subjected to blood draws and other bodily monitoring procedures. In exchange, they are paid. Healthy volunteers are, in a very direct sense, selling access to their bodies for pharmaceutical companies and their associates to run drugs through. In his ethnographic study of socalled professional guinea pigs, Roberto Abadie writes, "Paid volunteers are well aware of the demand for an idealized, perfectly healthy volunteer. They also realize that their (...)
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  14. With Cognitive Difference Can Have in Helping Us to Retain a Sense of Humility. The Authors in This Volume, for the Most Part, Pay Heed.Rebecca L. Walker - 2012 - Mind 121 (483):484.
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  15.  10
    Genomic Research with the Newly Dead: A Crossroads for Ethics and Policy.Rebecca L. Walker, Eric T. Juengst, Warren Whipple & Arlene M. Davis - 2014 - Journal of Law, Medicine and Ethics 42 (2):220-231.
    Recent advances in next generation sequencing along with high hopes for genomic medicine have inspired interest in genomic research with the newly dead. However, applicable law does not adequately determine ethical or policy responses to such research. In this paper we propose that such research stands at a crossroads between other more established biomedical clinical and research practices. In addressing the ethical and policy issues raised by a particular research project within our institution comparatively with these other practices, we illustrate (...)
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  16.  18
    Companion Animal Studies: Slipping Through a Research Oversight Gap.Rebecca L. Walker & Jill A. Fisher - 2018 - American Journal of Bioethics 18 (10):62-63.
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  17.  31
    Biodefense Research and the U.S. Regulatory Structure Whither Nonhuman Primate Moral Standing?L. Walker Rebecca & M. P. King Nancy - 2011 - Kennedy Institute of Ethics Journal 21 (3):277-310.
    Biodefense and emerging infectious disease animal research aims to avoid or ameliorate human disease, suffering, and death arising, or potentially arising, from natural outbreaks or intentional deployment of some of the world’s most dreaded pathogens. Top priority research goals include finding vaccines to prevent, diagnostic tools to detect, and medicines for smallpox, plague, ebola, anthrax, tularemia, and viral hemorrhagic fevers, among many other pathogens (National Institute of Allergy and Infectious Diseases [NIAID] priority pathogens). To this end, increased funding for conducting (...)
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  18.  3
    Picking and Choosing Among Phase I Trials: A Qualitative Examination of How Healthy Volunteers Understand Study Risks.Jill A. Fisher, Torin Monahan & Rebecca L. Walker - 2019 - Journal of Bioethical Inquiry 16 (4):535-549.
    This article empirically examines how healthy volunteers evaluate and make sense of the risks of phase I clinical drug trials. This is an ethically important topic because healthy volunteers are exposed to risk but can gain no medical benefit from their trial participation. Based on in-depth qualitative interviews with 178 healthy volunteers enrolled in various clinical trials, we found that participants focus on myriad characteristics of clinical trials when assessing risk and making enrolment decisions. These factors include the short-term and (...)
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  19.  2
    Picking and Choosing Among Phase I Trials: A Qualitative Examination of How Healthy Volunteers Understand Study Risks.Jill A. Fisher, Torin Monahan & Rebecca L. Walker - 2019 - Journal of Bioethical Inquiry 16 (4):535-549.
    This article empirically examines how healthy volunteers evaluate and make sense of the risks of phase I clinical drug trials. This is an ethically important topic because healthy volunteers are exposed to risk but can gain no medical benefit from their trial participation. Based on in-depth qualitative interviews with 178 healthy volunteers enrolled in various clinical trials, we found that participants focus on myriad characteristics of clinical trials when assessing risk and making enrolment decisions. These factors include the short-term and (...)
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  20.  1
    Picking and Choosing Among Phase I Trials: A Qualitative Examination of How Healthy Volunteers Understand Study Risks.Jill A. Fisher, Torin Monahan & Rebecca L. Walker - 2019 - Journal of Bioethical Inquiry 16 (4):535-549.
    This article empirically examines how healthy volunteers evaluate and make sense of the risks of phase I clinical drug trials. This is an ethically important topic because healthy volunteers are exposed to risk but can gain no medical benefit from their trial participation. Based on in-depth qualitative interviews with 178 healthy volunteers enrolled in various clinical trials, we found that participants focus on myriad characteristics of clinical trials when assessing risk and making enrolment decisions. These factors include the short-term and (...)
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  21.  1
    Picking and Choosing Among Phase I Trials: A Qualitative Examination of How Healthy Volunteers Understand Study Risks.Jill A. Fisher, Torin Monahan & Rebecca L. Walker - 2019 - Journal of Bioethical Inquiry 16 (4):535-549.
    This article empirically examines how healthy volunteers evaluate and make sense of the risks of phase I clinical drug trials. This is an ethically important topic because healthy volunteers are exposed to risk but can gain no medical benefit from their trial participation. Based on in-depth qualitative interviews with 178 healthy volunteers enrolled in various clinical trials, we found that participants focus on myriad characteristics of clinical trials when assessing risk and making enrolment decisions. These factors include the short-term and (...)
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  22.  12
    The Ethics of Species: An Introduction.Rebecca L. Walker - 2013 - International Studies in the Philosophy of Science 27 (2):225-228.
  23.  6
    Response to Open Peer Commentaries on “Looking for Trouble: Preventive Genomic Sequencing in the General Population and the Role of Patient Choice”.Gabriel Lázaro-Muñoz, John M. Conley, Arlene M. Davis, Marcia Van Riper, Rebecca L. Walker & Eric T. Juengst - 2015 - American Journal of Bioethics 15 (12):6-9.
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  24. The Good Life for Non-Human Animas: What Virtue Requires of Humans.Rebecca L. Walker - 2007 - In Rebecca L. Walker & Philip J. Ivanhoe (eds.), Working Virtue: Virtue Ethics and Contemporary Moral Problems. Oxford University Press.
     
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