BackgroundIn the Canadian Alliance for Healthy Hearts and Minds cohort, participants underwent magnetic resonance imaging of the brain, heart, and abdomen, that generated incidental findings. The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants were recruited with (...) a follow-up questionnaire administered to 909 participants at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% of participants, with the highest proportions found in the brain and abdomen. The majority of participants informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

Human freedom is the central theme of modern political philosophy, and G. W. F. Hegel offers perhaps the most profound and systematic modern attempt to understand the state as the realization of human freedom. In this comprehensive examination of Hegel’s philosophy of freedom, Paul Franco traces the development of Hegel’s ideas of freedom, situates them within his general philosophical system, and relates them to the larger tradition of modern political philosophy. Franco then applies Hegel’s understanding of liberty to certain problems (...) in contemporary political theory. He argues that Hegel offers a powerful reformulation of liberalism that escapes many of the problematic assumptions of traditional liberal doctrine and yet avoids falling into the romantic and relativistic excesses of a substantial communitarianism. Devoting the major portion of his attention to Hegel’s masterpiece the _Philosophy of Right_, published in 1821, Franco provides a clear and nontechnical guide to the challenging arguments Hegel presents. Franco establishes the necessary context within which to understand the work and draws on Hegel’s other writings, including the unpublished lecture notes, to illuminate it. For the Hegel specialist as well as the reader with a more general interest in political philosophy and modern intellectual history, this book offers significant insights into Hegel’s ideas on the theme of human liberty. (shrink)

Self-reflection, as the hallmark of the modern age, originates more profoundly with Dante than with Descartes. This book rewrites modern intellectual history, taking Dante’s lyrical language in Paradiso as enacting a Trinitarian self-reflexivity that gives a theological spin to the birth of the modern subject already with the Troubadours. Dante’s thought and work indicate an alternative modernity along the path not taken. This alternative shows up in Nicholas of Cusa’s conjectural science and in Giambattista Vico’s new science of imagination as (...) alternatives to positive empirical science. (shrink)

Franke reads the Divine Comedy through the insights into interpretation developed by hermeneutics, and at the same time uses Dante's poem, with its interpretive praxis based on a theological vision, to challenge prevailing assumptions about interpretation today. Copyright © Libri GmbH. All rights reserved.

Einstein, in his “Zur Elektrodynamik bewegter Körper”, gave a physical (operational) meaning to “time” of a remote event in describing “motion” by introducing the concept of “synchronous stationary clocks located at different places”. But with regard to “place” in describing motion, he assumed without analysis the concept of a system of co-ordinates.In the present paper, we propose a way of giving physical (operational) meaning to the concepts of “place” and “co-ordinate system”, and show how the observer can define both the (...) place and time of a remote event. Following Einstein, we consider another system “in uniform motion of translation relatively to the former”. Without assuming “the properties of homogeneity which we attribute to space and time”, we show that the definitions of space and time in the two systems are linearly related. We deduce some novel consequences of our approach regarding faster-than-light observers and particles, “one-way” and “two-way” velocities of light, symmetry, the “group property” of inertial reference frames, length contraction and time dilatation, and the “twin paradox”. Finally, we point out a flaw in Einstein’s argument in the “Electrodynamical Part” of his paper and show that the Lorentz force formula and Einstein’s formula for transformation of field quantities are mutually consistent. We show that for faster-than-light bodies, a simple modification of Planck’s formula for mass suffices. (Except for the reference to Planck’s formula, we restrict ourselves to Physics of 1905.). (shrink)

In 1931 the mathematical logician Kurt Godel published a revolutionary paper that challenged certain basic assumptions underpinning mathematics and logic. A colleague of Albert Einstein, his theorem proved that mathematics was partly based on propositions not provable within the mathematical system and had radical implications that have echoed throughout many fields. A gripping combination of science and accessibility, Godel’s Proof by Nagel and Newman is for both mathematicians and the idly curious, offering those with a taste for logic and philosophy (...) the chance to satisfy their intellectual curiosity. (shrink)

An able and clear defense of Bradley's principal theses and the underlying conception of metaphysical enterprise. "This is a book about a metaphysician, about metaphysics, and, most importantly, it attempts to develop elements of a metaphysical position long the lines of what is called Absolute Idealism." The Introduction takes up the Verificationists [[sic]] argument and two recent accounts of metaphysics. Part I devotes ten Chapters to the elucidation and defense of Bradley's conception of reality. It culminates in examining three alternative (...) accounts of "Real". Part II considers "the major philosophical theories of the self in order to defend Bradley's Theory of the self within his metaphysical scheme."--A. S. C. (shrink)

As a spiritual autobiography, Kierkegaard's The Point of View for My Work as an Author stands among such great works as Augustine's Confessions and Newman's Apologia pro Vita Sua. Yet Point of View is neither a confession nor a defense; it is an author's story of a lifetime of writing, his understanding of the maze of greatly varied works that make up his oeuvre. Upon the imminent publication of the second edition of Either/Or, Kierkegaard again intended to cease writing. Now (...) was the time for a direct "report to history" on the authorship as a whole. In addition to Point of View, which was published posthumously, the present volume also contains On My Work as an Author, a contemporary substitute, and the companion piece Armed Neutrality. (shrink)

The first major work in the history of philosophy to bear the title "Metaphysics" was the treatise by Aristotle that we have come to know by that name. But Aristotle himself did not use that title or even describe his field of study as 'metaphysics'; the name was evidently coined by the first century C.E. editor who assembled the treatise we know as Aristotle's Metaphysics out of various smaller selections of Aristotle's works. The title 'metaphysics' -- literally, 'after the Physics' (...) -- very likely indicated the place the topics discussed therein were intended to occupy in the philosophical curriculum. They were to be studied after the treatises dealing with nature (ta phusika). In this entry, we discuss the ideas that are developed in Aristotle's treatise. (shrink)

In Carnap’s autobiography, he tells the story how one night in January 1931, “the whole theory of language structure” in all its ramifications “came to [him] like a vision”. The shorthand manuscript he produced immediately thereafter, he says, “was the first version” of Logical Syntax of Language. This document, which has never been examined since Carnap’s death, turns out not to resemble Logical Syntax at all, at least on the surface. Wherein, then, did the momentous insight of 21 January 1931 (...) consist? We seek to answer this question by placing Carnap’s shorthand manuscript in the context of his previous efforts to accommodate scientific theories and metalinguistic claims within Wittgenstein’s Tractatus theory of meaning. The breakthrough of January 1931 consists, from this viewpoint, in the rejection of the Tractatus theory in favor of the meta-mathematical perspective of Hilbert, Gödel, and Tarski. This was not yet the standpoint of the published Logical Syntax, as we show, but led naturally to the “principle of tolerance” and thus to Carnap’s mature philosophy, in which the inconsistencies between this first view and the principle of tolerance, which survived into the published Syntax, were overcome. (shrink)

A layman's guide to the mechanics of Gödel's proof together with a lucid discussion of the issues which it raises. Includes an essay discussing the significance of Gödel's work in the light of Wittgenstein's criticisms.

In his book Shadows of the Mind: A search for the missing science of con- sciousness [SM below], Roger Penrose has turned in another bravura perfor- mance, the kind we have come to expect ever since The Emperor’s New Mind [ENM ] appeared. In the service of advancing his deep convictions and daring conjectures about the nature of human thought and consciousness, Penrose has once more drawn a wide swath through such topics as logic, computa- tion, artificial intelligence, quantum physics (...) and the neuro-physiology of the brain, and has produced along the way many gems of exposition of difficult mathematical and scientific ideas, without condescension, yet which should be broadly appealing. 1 While the aims and a number of the topics in SM are the same as in ENM, the focus now is much more on the two axes that Pen- rose grinds in earnest. Namely, in the first part of SM he argues anew and at great length against computational models of the mind and more specifi- cally against any account of mathematical thought in computational terms. Then in the second part, he argues that there must be a scientific account of consciousness but that will require a (still to be found) non-computational extension or modification of present-day quantum physics. (shrink)

Sebastian Gardner competently tackles one of Sartre's more complex and challenging works in this new addition to the Reader's Guides series.

Our study presents an overview of the issues that were brought forward by participants of a moral case deliberation (MCD) project in two elderly care organizations. The overview was inductively derived from all case descriptions (N = 202) provided by participants of seven mixed MCD groups, consisting of care providers from various professional backgrounds, from nursing assistant to physician. The MCD groups were part of a larger MCD project within two care institutions (residential homes and nursing homes). Care providers are (...) confronted with a wide variety of largely everyday ethical issues. We distinguished three main categories: ‘resident’s behavior’, ‘divergent perspectives on good care’ and ‘organizational context’. The overview can be used for agendasetting when institutions wish to stimulate reflection and deliberation. It is important that an agenda is constructed from the bottom-up and open to a variety of issues. In addition, organizing reflection and deliberation requires effort to identify moral questions in practice whilst at the same time maintaining the connection with the organizational context and existing communication structures. Once care providers are used to dealing with divergent perspectives, inviting different perspectives (e.g. family members) to take part in the deliberation, might help to identify and address ethical ‘blind spots’. (shrink)

Nearly as famous as his denial of the existence of matter is Berkeley's insistence that his philosophy is somehow a defense of commonsense. This is most often taken to mean that Berkeley thinks of his philosophy as supporting commonsense beliefs. However, the inadequacies of such views have persuaded some to disregard entirely Berkeley's claims about commonsense. Both readings are undesirable. Extant interpretations misunderstand the relationship between Berkeley's philosophy and commonsense. In this paper, I present a new account of how to (...) understand Berkeley's so-called defense of commonsense; it is not a defense-cum­-apology for commonsense beliefs, but a defensive attack against a skeptical threat. I then examine two rival accounts of the defense of commonsense and show how each fails to satisfy the criteria for a successful account. Finally, I briefly address the implications this view has for future scholarship. (shrink)

Plato’s dialogue Cratylus focuses on being and human dependence on words, or the essential truths about the human condition. Arguing that comedy is an essential part of Plato's concept of language, S. Montgomery Ewegen asserts that understanding the comedic is key to an understanding of Plato's deeper philosophical intentions. Ewegen shows how Plato’s view of language is bound to comedy through words and how, for Plato, philosophy has much in common with playfulness and the ridiculous. By tying words, language, and (...) our often uneasy relationship with them to comedy, Ewegen frames a new reading of this notable Platonic dialogue. (shrink)

Kant’s dissertation for the Master’s degree Succinct Exposition of Some Meditations on Fire was written in Latin in 1755 as a sample (specimen) preceding a Master’s exam, but its first printing did not appear until 1838. What is the relevance of this Master’s dissertation for historical and philosophical studies? To answer this question I analyse the structure and give a brief summary of the dissertation, look at the history of its writing and try to identify the place of this work (...) among Kant’s other papers on natural philosophy. I then demonstrate that Kant’s concept of ether as an elastic matter of fire, heat and light containing the forces of attraction and repulsion originates in the dissertation On Fire. I identify the provisions in Kant’s early works which he later develops in the Master’s dissertation and establish continuity between the text of On Fire and the so-called Physical Monadology, draw parallels between the ideas enunciated by Kant in his first dissertation and the interpretation of ether in the printed works that followed. Finally, I put forward the hypothesis of the heuristic potential of the On Fire treatise for the analysis of Kant’s manuscript legacy. Perhaps this dissertation will enable researchers to clear up some tangled propositions in Kant’s Opus Postumum. However, a series of further studies is needed to verify the hypothesis. (shrink)

In this highly original account of Bishop George Berkeley's epistemological and metaphysical theories, George S. Pappas seeks to determine precisely what doctrines the philosopher held and what arguments he put forward to support them. Specifically, Pappas overturns accepted opinions about Berkeley's famous attack on the Lockean doctrine of abstract ideas. Berkeley's criticism of these ideas had been thought relevant only to his views on language and to his nominalism; Pappas persuasively argues that Berkeley's ideas about abstraction are crucial to nearly (...) all of the fundamental principles that he defends. Pappas demonstrates how an adequate appreciation of Berkeley's views on abstraction can lead to an improved understanding of his important principle of esse is percipi, and of the arguments Berkeley proposes in support of this principle. Pappas also takes up Berkeley's widely rejected claim to be a philosopher of common sense. He assesses the validity of this self-description and considers why Berkeley might have chosen to align himself with a commonsense position. Pappas shows how three core concepts—abstraction, perception, and common sense—are central to and interdependent in the work of one of the major figures of early modern Western thought. (shrink)

The purpose of Pope John Paul''s encyclicalCentesimus Annus (CA) is to propound the foundations of a just economic order and to sketch its essential characteristics. As such he essentially provides an orientation or moral compass for the political economy rather than a precise road map. This article first reviews the principal components of CA and then analyzes and evaluates its central contentions on both cultural and economic grounds.

C.H. Waddington is today remembered chiefly as a Drosophila developmental geneticist who developed the concepts of “canalization” and “the epigenetic landscape.” In his lifetime, however, he was widely perceived primarily as a critic of Neo-Darwinian evolutionary theory. His criticisms of Neo-Darwinian evolutionary theory were focused on what he saw as unrealistic, “atomistic” models of both gene selection and trait evolution. In particular, he felt that the Neo-Darwinians badly neglected the phenomenon of extensive gene interactions and that the “randomness” of mutational (...) effects, posited in the theory, was a false postulate. This last criticism dealt with the phenomenon known today as “developmental constraints.” Although population genetics itself has evolved considerably from its form at mid-20th century, much of Waddington’s critique, it is argued here, retains cogency. Yet, he did not attempt to develop a full-fledged alternative theory himself. Perhaps most surprisingly, in retrospect, is that he did not try to marry his work on gene interactions in development with his evolutionary interests, to create a theory of “genetic networks” and their evolution. Whether evolutionary genetics today will incorporate “network thinking” as a central element or whether there will be a general retreat to the more atomistic approach offered by genomics, remains an open question. (shrink)

Goff argues that Galileo erred in denying that sensory qualities are present in the physical world and that we should correct his error by supposing that all matter has an intrinsic conscious aspect. This paper argues that we should be open to another theoretical option. Galileo's real error, I argue, was not about the location of sensory qualities, but about their very existence. Like most people, Galileo assumed that sensory qualities are instantiated somewhere. I argue that this is a theoretical (...) assumption which can and should be questioned. If we drop it, we can give a natural account of the function of sensory quality talk and explain how our puzzlement about consciousness arises. (shrink)

As these opening quotes acknowledge, the Prisoner’s Dilemma (PD) represents a core puzzle within the formal mathematics of game theory.3 Its rise in conspicuity is evident figure 2.1 above demonstrating a relatively steady rise in incidences of the phrase’s usage between 1960 to 1995, with a stable presence persisting into the twenty first century. This famous two-person “game,” with a stock narrative cast in terms of two prisoners who each independently must choose whether to remain silent or speak, each advancing (...) self-interest at the expense of the other and thereby achieving a mutually suboptimal outcome, mires any social interaction it is applied to into perplexity. The logic of this game proves the inverse of Adam Smith’s invisible hand: individuals acting on self interest will achieve a mutually suboptimal outcome. However, as this chapter illuminates, the assumptions underlying game theory drive this conclusion. (shrink)

This paper argues that Immanuel Kant’s practical philosophy contains a coherent, albeit implicit, defense of the legitimacy of capital punishment, one that refutes the most important objections leveled against it. I first show that Kant is consistent in his application of the ius talionis. I then explain how Kant can respond to the claim that death penalty violates the inviolable right to life. To address the most significant objection – the claim that execution violates human dignity – I argue that (...) motives of honor, as Kant conceives it, require a rational person to will her own execution, were she to commit murder. (shrink)

G. E. Moore observed that to assert, 'I went to the pictures last Tuesday but I don't believe that I did' would be 'absurd'. Over half a century later, such sayings continue to perplex philosophers. In the definitive treatment of the famous paradox, Green and Williams explain its history and relevance and present new essays by leading thinkers in the area.

"One basic and underlying assumption of this investigation will be that there is a distinct continuity and development in Berkeley's thought which can be traced through all of his reflective analyses of the problem of perception." The essay argues for Berkeley's theory of perception as a "prototype of the phenomenalists." It argues also for Berkeley's incorporation of elements from the representative theory of perception. Of special interest is the treatment of Berkeley's doctrine of "suggestion" and its connection with the role (...) of imagination in the perception of physical objects. The linguistic aspect of Berkeley's work is minimized. Berkeley's theory of notions receives only a passing reference. The last third of the book is a clear and useful discussion of Berkeley and contemporary phenomenalism. It is suggested, though not shown, that Berkeley has affinity with contemporary phenomenology of perception.--A. S. C. (shrink)