The prevention, treatment and management of disease are closely linked to how the causes of a particular disease are explained. For multi-factorial conditions, the causal explanations are inevitably complex and competing models may exist to explain the same condition. Selecting one particular causal explanation over another will carry practical and ethical consequences that are acutely relevant for health policy. In this paper our focus is two-fold; the different models of causal explanation that are put forward within current scientific literature for (...) the high and rising prevalence of the common complex conditions of coronary artery disease and type 2 diabetes mellitus ; and how these explanations are taken up within national health policy guidelines. We examine the causal explanations for these two conditions through a systematic database search of current scientific literature. By identifying different causal explanations we propose a three-tier taxonomy of the most prominent models of explanations: evolutionary, lifecourse, and lifestyle and environment. We elaborate this taxonomy with a micro-level thematic analysis to illustrate how some explanations are semantically and rhetorically foregrounded over others. We then investigate the uptake of the scientific causal explanations in health policy documents with regard to the prevention and management recommendations of current National Service Frameworks for CAD and T2D. Our findings indicate a lack of congruence between the complexity and frequent overlap of causal explanations evident in the scientific literature and the predominant focus on lifestyle recommendations found in the mainstream health policy documents. (shrink)

In this article, we examine the role played by heterogeneity in the popular “connections model” of Jackson and Wolinsky (J Econ Theory 71(1):355–365, 1996). We prove that when heterogeneity with respect to the values of resources, or the information decay parameter, depends on the identity of the player who forms the link, and the player who receives the link, all networks can be supported as Nash. Moreover, we show that Nash networks may not always exist. Interestingly, in the absence of (...) decay, neither result occurs in a model with value heterogeneity. Finally, we show that when reducing heterogeneity, all networks cannot be supported as Nash, and the non-existence problem also disappears. (shrink)

We provide existence results in a game with local spillovers where the payoff function satisfies both convexity and the strategic substitutes property. We show that there always exists a stable pairwise network in this game, and provide a condition which ensures the existence of pairwise equilibrium networks.

Les fondements théoriques d'une analyse des activités dans les discours professionnels illustrée par des données issues de rencontres en conseil génétique sont présentés ici. En prenant l'activité comme unité de base de l'action, je me réfère rapidement à «l'activité théorique» proposée par Leontyev, rajoutant les notions de «jeux de langage» de Wittgenstein et de «types d'activités» de Levinson. L'activité d'analyse dans les discours professionnels doit aller au-delà du seul codage des instances de l'usage du langage et doit s'orienter vers la (...) compréhension d'une écologie spécifique de l'activité, incluant les dimensions relationnelles et de rôles des participants présents ou absents. Cette interprétation peut s'analyser en considérant le cadre thématique et interactionnel d'une situation donnée grâce à la prise en compte des propriétés structurelles et relationnelles dans l'usage du langage.In this paper I present a theoretical basis for activity analysis in professional discourse settings followed by an illustration of data from the genetic counseling encounters. By taking activity as the basic unit of action, I briefly draw on "activity theory" as proposed by Leontyev, supplemented by Wittgenstein's notion of "language games" and Levinson's notion of "activity types". I argue that activity analysis in the professional discourse settings has to go beyond mere coding of instances of language use towards an interpretive understanding of the activity-specific ecology, including the role-relational dimensions of co-present and absent participants. Such an interpretive task can be achieved through thematic and interactional mapping of a given encounter by taking into consideration the structural and relational properties situated language use. (shrink)