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Sabina Leonelli
University of Exeter
  1. What’s so Special About Model Organisms?Rachel A. Ankeny & Sabina Leonelli - 2011 - Studies in History and Philosophy of Science Part A 42 (2):313-323.
    This paper aims to identify the key characteristics of model organisms that make them a specific type of model within the contemporary life sciences: in particular, we argue that the term “model organism” does not apply to all organisms used for the purposes of experimental research. We explore the differences between experimental and model organisms in terms of their material and epistemic features, and argue that it is essential to distinguish between their representational scope and representational target. We also examine (...)
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  2.  23
    Repertoires: A Post-Kuhnian Perspective on Scientific Change and Collaborative Research.Rachel A. Ankeny & Sabina Leonelli - 2016 - Studies in History and Philosophy of Science Part A 60:18-28.
  3.  38
    Integrating Data to Acquire New Knowledge: Three Modes of Integration in Plant Science.Sabina Leonelli - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):503-514.
    This paper discusses what it means and what it takes to integrate data in order to acquire new knowledge about biological entities and processes. Maureen O’Malley and Orkun Soyer have pointed to the scientific work involved in data integration as important and distinct from the work required by other forms of integration, such as methodological and explanatory integration, which have been more successful in captivating the attention of philosophers of science. Here I explore what data integration involves in more detail (...)
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  4. Classificatory Theory in Data-Intensive Science: The Case of Open Biomedical Ontologies.Sabina Leonelli - 2012 - International Studies in the Philosophy of Science 26 (1):47 - 65.
    Knowledge-making practices in biology are being strongly affected by the availability of data on an unprecedented scale, the insistence on systemic approaches and growing reliance on bioinformatics and digital infrastructures. What role does theory play within data-intensive science, and what does that tell us about scientific theories in general? To answer these questions, I focus on Open Biomedical Ontologies, digital classification tools that have become crucial to sharing results across research contexts in the biological and biomedical sciences, and argue that (...)
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  5.  92
    Scientific Understanding: Philosophical Perspectives.Henk De Regt, Sabina Leonelli & Kai Eigner (eds.) - 2009 - University of Pittsburgh Press.
    The chapters in this book highlight the multifaceted nature of the process of scientific research.
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  6.  48
    Performing Abstraction: Two Ways of Modelling Arabidopsis Thaliana.Sabina Leonelli - 2008 - Biology and Philosophy 23 (4):509-528.
  7.  42
    Re-Thinking Organisms: The Impact of Databases on Model Organism Biology.Sabina Leonelli & Rachel A. Ankeny - 2012 - Studies in History and Philosophy of Science Part C 43 (1):29-36.
  8.  10
    Documenting the Emergence of Bio-Ontologies: Or, Why Researching Bioinformatics Requires HPSSB.Sabina Leonelli - 2010 - History and Philosophy of the Life Sciences 32 (1).
  9.  24
    Bio-Ontologies as Tools for Integration in Biology.Sabina Leonelli - 2008 - Biological Theory 3 (1):7-11.
  10.  60
    On the Locality of Data and Claims About Phenomena.Sabina Leonelli - 2009 - Philosophy of Science 76 (5):737-749.
    Bogen and Woodward characterized data as embedded in the context in which they are produced (‘local’) and claims about phenomena as retaining their significance beyond that context (‘nonlocal’). This view does not fit sciences such as biology, which successfully disseminate data via packaging processes that include appropriate labels, vehicles, and human interventions. These processes enhance the evidential scope of data and ensure that claims about phenomena are understood in the same way across research communities. I conclude that the degree of (...)
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  11.  25
    Growing Weed, Producing Knowledge An Epistemic History of Arabidopsis Thaliana.Sabina Leonelli - 2007 - History and Philosophy of the Life Sciences 29 (2):193 - 223.
    Arabidopsis is currently the most popular and well-researched model organism in plant biology. This paper documents this plant's rise to scientific fame by focusing on two interrelated aspects of Arabidopsis research. One is the extent to which the material features of the plant have constrained research directions and enabled scientific achievements. The other is the crucial role played by the international community of Arabidopsis researchers in making it possible to grow, distribute and use plant specimen that embody these material features. (...)
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  12.  34
    Data Interpretation in the Digital Age.Sabina Leonelli - 2014 - Perspectives on Science 22 (3):397-417.
    Scientific knowledge production is currently affected by the dissemination of data on an unprecedented scale. Technologies for the automated production and sharing of vast amounts of data have changed the way in which data are handled and interpreted in several scientific domains, most notably molecular biology and biomedicine. In these fields, the activity of data gathering has become increasingly technology-driven, with machines such as next generation genome sequencers and mass spectrometers generating billions of data points within hours, and with little (...)
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  13.  15
    Focusing on Scientific Understanding.Henk W. de Regt, Sabina Leonelli & K. Eigner - 2009 - In Henk De Regt, Sabina Leonelli & Kai Eigner (eds.), Scientific Understanding: Philosophical Perspectives. University of Pittsburgh Press.
  14.  36
    Infrared Metaphysics: Radiation and Theory-Choice. Part.Hasok Chang & Sabina Leonelli - 2005 - Studies in History and Philosophy of Science Part A 36 (4):687-706.
    We continue our discussion of the competing arguments in favour of the unified theory and the pluralistic theory of radiation advanced by three nineteenth-century pioneers: Herschel, Melloni, and Draper. Our narrative is structured by a consideration of the epistemic criteria relevant to theory-choice; the epistemic focus highlights many little-known aspects of this relatively well-known episode. We argue that the acceptance of light-heat unity in this period cannot be credibly justified on the basis of common evaluative criteria such as simplicity and (...)
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  15.  47
    What Counts as Scientific Data? A Relational Framework.Sabina Leonelli - 2015 - Philosophy of Science 82 (5):810-821.
    This paper proposes an account of scientific data that makes sense of recent debates on data-driven and ‘big data’ research, while also building on the history of data production and use particularly within biology. In this view, ‘data’ is a relational category applied to research outputs that are taken, at specific moments of inquiry, to provide evidence for knowledge claims of interest to the researchers involved. They do not have truth-value in and of themselves, nor can they be seen as (...)
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  16.  9
    Understanding in Biology: The Impure Nature of Biological Knowledge.Sabina Leonelli - 2009 - In Henk De Regt, Sabina Leonelli & Kai Eigner (eds.), Scientific Understanding: Philosophical Perspectives. University of Pittsburgh Press. pp. 189--209.
  17.  2
    Where Health and Environment Meet: The Use of Invariant Parameters in Big Data Analysis.Sabina Leonelli & Niccolò Tempini - 2018 - Synthese:1-20.
    The use of big data to investigate the spread of infectious diseases or the impact of the built environment on human wellbeing goes beyond the realm of traditional approaches to epidemiology, and includes a large variety of data objects produced by research communities with different methods and goals. This paper addresses the conditions under which researchers link, search and interpret such diverse data by focusing on “data mash-ups”—that is the linking of data from epidemiology, biomedicine, climate and environmental science, which (...)
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  18.  19
    Infrared Metaphysics: The Elusive Ontology of Radiation. Part 1.Hasok Chang & Sabina Leonelli - 2005 - Studies in History and Philosophy of Science Part A 36 (3):477-508.
    Hardly any ontological result of modern science is more firmly established than the fact that infrared radiation differs from light only in wavelength; this is part of the modern conception of the continuous spectrum of electromagnetic radiation reaching from radio waves to gamma radiation. Yet, like many such evident truths, the light-infrared unity was an extremely difficult thing to establish. We examine the competing arguments in favour of the unified and pluralistic theories of radiation, as put forward in the first (...)
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  19.  13
    The Crucial Role of Models in Science.Sabina Leonelli - forthcoming - Metascience:1-3.
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  20.  1
    Re-Thinking Reproducibility as a Criterion for Research Quality.Sabina Leonelli - unknown
    A heated debate surrounds the significance of reproducibility as an indicator for research quality and reliability, with many commentators linking a "crisis of reproducibility" to the rise of fraudulent, careless and unreliable practices of knowledge production. Through the analysis of discourse and practices across research fields, I point out that reproducibility is not only interpreted in different ways, but also serves a variety of epistemic functions depending on the research at hand. Given such variation, I argue that the uncritical pursuit (...)
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  21.  1
    The Time of Data: Time-Scales of Data Use in the Life Sciences.Sabina Leonelli - 2017 - Philosophy of Science.
    This paper considers the temporal dimension of data processing and use, and the ways in which it affects the production and interpretation of knowledge claims. I start by distinguishing the time at which data collection, dissemination and analysis occur from the time in which the phenomena for which data serve as evidence operate. Building on the analysis of two examples of data re-use from modelling and experimental practices in biology, I then argue that Dt affects how researchers select and interpret (...)
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  22.  25
    Classificatory Theory in Biology.Sabina Leonelli - 2013 - Biological Theory 7 (4):338-345.
    Scientific classification has long been recognized as involving a specific style of reasoning and doing research, and as occasionally affecting the development of scientific theories. However, the role played by classificatory activities in generating theories has not been closely investigated within the philosophy of science. I argue that classificatory systems can themselves become a form of theory, which I call classificatory theory, when they come to formalize and express the scientific significance of the elements being classified. This is particularly evident (...)
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  23.  22
    Introduction: On the Philosophy of Science in Practice. [REVIEW]Marcel Boumans & Sabina Leonelli - 2013 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 44 (2):259-261.
  24.  22
    Karen-Sue Taussig: Ordinary Genomes: Science, Citizenship and Genetic Identities. [REVIEW]Sabina Leonelli - 2012 - Acta Biotheoretica 60 (3):319-322.
    Karen-Sue Taussig: Ordinary Genomes: Science, Citizenship and Genetic Identities Content Type Journal Article Category Book Review Pages 1-4 DOI 10.1007/s10441-012-9150-8 Authors Sabina Leonelli, Department of Sociology and Philosophy, ESRC Centre for Genomics in Society, University of Exeter, Exeter, Devon, UK Journal Acta Biotheoretica Online ISSN 1572-8358 Print ISSN 0001-5342.
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  25.  19
    Bioethics Authorship in Context: How Trends in Biomedicine Challenge Bioethics.Rachel A. Ankeny & Sabina Leonelli - 2011 - American Journal of Bioethics 11 (10):22 - 24.
    The American Journal of Bioethics, Volume 11, Issue 10, Page 22-24, October 2011.
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  26.  20
    Symposium Issue: Philosophy of Biology in Flanders and the Netherlands.Sabina Leonelli & Thomas Reydon - 2005 - Acta Biotheoretica 53 (2):55-56.
  27.  14
    An Epistemology of the Concrete: Twentieth-Century Histories of Life.Sabina Leonelli - 2011 - International Studies in the Philosophy of Science 25 (4):420-422.
    International Studies in the Philosophy of Science, Volume 25, Issue 4, Page 420-422, December 2011.
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  28.  7
    The Scientific Importance of Asking Questions at Meetings: Why Virtual Debate is Not Enough.Maureen A. O'Malley & Sabina Leonelli - 2011 - Bioessays 33 (1):35-37.
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  29.  4
    Making Organisms Model Human Behavior: Situated Models in North-American Alcohol Research, Since 1950.Rachel A. Ankeny, Sabina Leonelli, Nicole C. Nelson & Edmund Ramsden - 2014 - Science in Context 27 (3):485-509.
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  30.  2
    Infrared Metaphysics: Radiation and Theory-Choice. Part 2.Hasok Chang & Sabina Leonelli - 2005 - Studies in History and Philosophy of Science Part A 36 (4):687-706.
    We continue our discussion of the competing arguments in favour of the unified theory and the pluralistic theory of radiation advanced by three nineteenth-century pioneers: Herschel, Melloni, and Draper. Our narrative is structured by a consideration of the epistemic criteria relevant to theory-choice; the epistemic focus highlights many little-known aspects of this relatively well-known episode. We argue that the acceptance of light-heat unity in this period cannot be credibly justified on the basis of common evaluative criteria such as simplicity and (...)
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  31. Naar een open dialoog tussen de wetenschap en de wetenschapsstudies.Sabina Leonelli - 2007 - Algemeen Nederlands Tijdschrift voor Wijsbegeerte 3.
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  32. Ordinary Genomes: Science, Citizenship and Genetic Identities. [REVIEW]Sabina Leonelli - 2012 - Acta Biotheoretica 60 (3):319-322.
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