Mere inability, which refers to what persons are naturally unable to do, is traditionally thought to be distinct from unfreedom, which is a social type of constraint. The advent of biomedical enhancement, however, challenges the idea that there is a clear division between mere inability and unfreedom. This is because bioenhancement makes it possible for some people’s mere inabilities to become matters of unfreedom. In this paper, I discuss several ways that this might occur: first, bioenhancement can exacerbate social pressures (...) to enhance one’s abilities; second, people may face discrimination for not enhancing; third, the new abilities made possible due to bioenhancement may be accompanied by new inabilities for the enhanced and unenhanced; and finally, shifting values around abilities and inabilities due to bioenhancement may reinforce a pre-existing ableism about human abilities. As such, we must give careful consideration to these potential unfreedom-generating outcomes when it comes to our moral evaluations of bioenhancement. (shrink)

In this article, I critique the commonly accepted distinction between commercial and altruistic surrogacy arrangements. The moral legitimacy of surrogacy, I claim, does not hinge on whether it is paid (‘commercial’) or unpaid (‘altruistic’); rather, it is best determined by appraisal of virtue-abiding conditions constitutive of the surrogacy arrangement. I begin my article by problematising the prevailing commercial/altruistic distinction; next, I demonstrate that an assessment of the virtue-abiding or non-virtue-abiding features of a surrogacy is crucial to navigating questions about the (...) moral legitimacy of surrogacy; in the final part, I reject other moral heuristics that might be proposed as alternatives to the commercial/altruistic dichotomy, and reiterate that a virtue-ethical framework is the most suitable way forward. (shrink)

There is a need recognized by the National Institute of Dental & Craniofacial Research and the National Cancer Institute to advance basic, translational and clinical saliva research. The goal of the Salivaomics Knowledge Base (SKB) is to create a data management system and web resource constructed to support human salivaomics research. To maximize the utility of the SKB for retrieval, integration and analysis of data, we have developed the Saliva Ontology and SDxMart. This article reviews the informatics advances in saliva (...) diagnostics made possible by the Saliva Ontology and SDxMart. (shrink)

In this paper, I claim that live uterus donors ought to be considered for the possibility of compensation. I support my claim on the basis of comparable arguments which have already been applied to gamete donation, surrogacy, and other kinds of organ donation. However, I acknowledge that there are specificities associated with uterus donation, which make the issue of incentive and reward a harder ethical case relative to gamete donation, surrogacy, and other kinds of organ donation. Ultimately, I contend that (...) while reimbursement for the costs incurred by live uterus donors should be treated as a necessary ethical minimum, how much further we ought to remunerate uterus donations remains an open question. (shrink)

Natalie Stoljar posits that those who have internalized oppressive norms lack normative competence, which requires true beliefs and critical reflection. A lack of normative competence makes agents nonautonomous, according to Stoljar. This framework is thereby meant to address what she calls the “feminist intuition”—the intuition that oppressive norms are incompatible with autonomy. On my view, however, Stoljar’s normative competence account of autonomy is subject to a worrying problem. Her account misattributes nonautonomy to those who perpetrate the oppression, making those who (...) are oppressed and those who oppress count as equally nonautonomous. I argue that this is implausible and demonstrate in this paper that we can establish an asymmetry of autonomy between those who oppress others and those who are made the target of oppression. (shrink)

A tic disorder (TD) is a neurodevelopmental disorder characterized by tics, which are repetitive movements and/or vocalizations that occur due to aberrant sensory gating. Its pathophysiology involves dysfunction in multiple parts of the cortico-striato-thalamo-cortical circuits. Spontaneous brain activity during the resting state can be used to evaluate the baseline brain state, and it is associated with various aspects of behavior and cognitive processes. Theta–gamma coupling (TGC) is an emerging technique for examining how neural networks process information through interactions. However, the (...) resting-state TGC of patients with TD and its correlation with cognitive function have not yet been studied. We investigated the resting-state TGC of 13 patients with TD and compared it with that of 13 age-matched healthy children. The participants underwent resting-state electroencephalography with their eyes closed. At the global level, patients with TD showed a significantly lower resting-state TGC than healthy children. Resting-state TGC with the eyes closed was significantly negatively correlated with the attention quotient calculated for omission errors in a selective visual attention test. These findings indicate that the resting-state brain network, which is important for the attentional processing of visual information, is dysfunctional in patients with TD. Additionally, these findings support the view that TGC reflects information processing and signal interactions at the global level. Patients with TD may have difficulty gating irrelevant sensory information in the resting state while their eyes are closed. (shrink)

The Iowa Gambling Task (IGT) simulates uncertain gains and losses in real life situations and thus is a good measure of uncertain decision making. The role of working memory (WM) in IGT performance still remains unclear. The present study aimed to examine the effect of WM on IGT performance. Three groups of participants matched on gender ratio were randomly assigned to no WM load, low WM load, and high WM load conditions. Initially the three groups did not show significant difference (...) in WM capacity. They finished a modified version of IGT and then their implicit learning effect and explicit cognition on IGT were assessed. Results indicated a linear increasing trend of IGT performance among high WM load, low WM load and no WM load groups; participants in the no WM load and low WM load groups revealed implicit learning effect, while participants in the high WM load group did not; all participants showed explicit cognition on IGT to the same level. These results suggested that participants in the high WM load group showed good explicit cognition to IGT but showed poor performance. This pattern is similar to frontal patients. Further studies should be conducted to explore this issue. (shrink)

In moral and political philosophy, topics like the distributive inequities conferred via special partial relationships – family relationships, for example – have been frequently debated. However, the epistemic dimensions of such partiality are seldom discussed in the ethical context, and the topic of partial relationships rarely feature in the realm of social epistemology. My view is that the role of partial relationships is worth exploring to enrich our understanding of epistemic injustice and its transmission. I claim that epistemic features typical (...) of partial relationships make phenomena like epistemic injustice easier to mask, more difficult to identify, and harder to correct. (shrink)

Ascribing autonomous status to agents is a valuable practice. As such, we ought to care about how we engage in practices of autonomy ascription. However, disagreement between first-personal experiences of an agent's autonomy and third-personal determinations of their autonomy presents challenges of ethical and epistemic concern. My view is that insights from a dialogical rather than nondialogical account of autonomy give us the resources to combat the challenges associated with autonomy ascription. I draw on Andrea Westlund's account of dialogical autonomy—on (...) which autonomy requires a dialogical disposition to hold oneself answerable to external critical perspectives—to make my case. (shrink)

BackgroundFatigue is an important factor for the safety of ships. In order to alleviate fatigue of the seafarers, the STCW Convention has made many regulations on the working time of seafarers. At present, if a crew member takes only one day off at home before returning to work on the ship, the working time on the ship must be re-calculated again. If the time spent at home is not sufficient to allow the crew to recover, the regulations of only stipulating (...) the working time, not stipulating the home vacation time, cannot guarantee the crew’s fatigue been well controlled. The aim of present study is to explore the relationship between vacation schedule and fatigue of the seafarers.MethodsIn present study, a simplified stress scale developed by the Ministry of Labor of Japan has been used as a measurement tool. The method of stratified sampling was adopted. Data collection mainly came from domestic ocean-going seafarers. Analysis was conducted using the Cross analysis and hierarchical multiple regression analysis methods.ResultsWe found that there was no difference between crew members of different positions in terms of average vacation time and on-board service time. The length of last vacation time and this service time for seafarers of different positions showed obvious differences. The rank has a significant effect on the length of the last vacation and the length of this service time. Also, the results showed that there was a significant negative correlation between the duration of vacation and overall fatigue, while there was a significant positive correlation between the length of service time on board and overall fatigue.ConclusionThe results indicated that a reasonable vacation schedule was crucial for the relief of the seafarers’ fatigue, and also played a positive role in the state of working on the ship again. (shrink)

Nos séculos XII e XIII surgiram as sumas teológicas, nas quais distingue-se uma forma literária externa, com a ordenação da matéria e o desenvolvimento do discurso, e, de outro, a forma interna, como uma ideia sistematizadora. Os autores analisam as obras da época para descobrir nelas aspectos comuns e diferenças.

al-Ījī's epitome of his Mawāqif fī ʻilm al-kalām on Islamic theology.

Individualistic traditions of autonomy have long been critiqued by feminists for their atomistic and asocial presentation of human agents. Relational approaches to autonomy were developed as an alternative to these views. Relational accounts generally capture a more socially informed picture of human agents, and aim to differentiate between social phenomena that are conducive to our agency versus those that pose a hindrance to our agency. In this article, I explore the various relational conceptualizations of autonomy profferred to date. I critically (...) review some of the ongoing internal disputes within the relational autonomy literature, and conclude the article by taking stock of the value of relational autonomy despite these unresolved debates. (shrink)

Should involuntarily childless people have the sameopportunities to access parenthood as those who are not involuntarily childless? In the context of assisted reproductive technologies, affirmative answers to this question are often cashed out in terms of positive rights, including rights to third-party reproduction. In this paper, wecritically explore the scope and extent to which any such right would hold up morally. Ultimately, we argue for a departure away from positive parental rights. Instead, we argue that the state has an imperfect (...) duty to benefit involuntarily childless people in relation to their parental aspirations. (shrink)

The formation of the character of Sun Wukong has remained one of the most controversial issues in the field of Xiyou ji studies. While acknowledging that different strands might have fed into the image of Sun Wukong in the sixteenth- century novel Xiyou ji, this paper calls attention to complex and sometimes contradictory representations of Sun Wukong’s sexuality and explores the mechanism of displacement that subtly operates in the novel and reveals itself through such representations. It further demonstrates the dual (...) function performed by the displacement of Sun Wukong’s sexuality: on the one hand, it connects Sun Wukong to the image of the lustful ape in the white ape tradition; on the other hand, such displacement allows him to utilize and transcend his desire by experiencing the process of awakening to kong 空 by means of se 色 on his path to enlightenment. Therefore, a reexamination of Sun Wukong through the lens of sexuality helps draw together these two seemingly separate aspects and reveals a narrative in which Sun Wukong’s sexual desire not only encodes his hidden past associated with the white ape tradition but also generates significant meaning in light of the Buddhist context, that is, the notion that erotic encounters and fulfillment of sexual desire can be integrated into the Buddhist journey to enlightenment. (shrink)

BackgroundTo explore how self-disclosure leads to post-traumatic growth in adults who have experienced traumatic events, this study identified the relationship between self-disclosure and post-traumatic growth in Korean adults. We examined a parallel multiple mediating model for this relationship.MethodsParticipants were 318 Korean male and female adult participants aged 20 years or older who had experienced trauma. We measured deliberate rumination, positive social responses, and the meaning of life as mediating variables.ResultsThe results revealed that the study variables positively correlated with PTG. Self-disclosure (...) was positively correlated with deliberate rumination, positive social responses, and meaning of life. In the multiple mediating model, deliberate rumination, positive social responses, and meaning of life mediated the relationship between self-disclosure and PTG.ConclusionSelf-disclosure, deliberate rumination, positive social responses, and meaning of life play an important role in the growth of adults who have experienced traumatic events. The findings of this study should provide valuable information for future research and for mental health professionals who want to promote the PTG of their clients. (shrink)

Because many involuntarily childless people have equal interests in benefitting from assisted reproductive technologies like in vitro fertilization as a mode of treatment, we have normative reasons to ensure inclusive access to such interventions for as many of these people as is reasonable and possible. However, the prevailing eligibility criterion for access to assisted reproductive technologies—'infertility'—is inadequate to serve the goal of inclusive access. This is because the prevailing frameworks of infertility, which include medical and social infertility, fail to precisely (...) capture and unify the relevance of certain involuntarily childless experiences as warranting assisted reproductive technology (ART) treatment. I argue that the least we can do for those who have an interest in accessing ARTs is to conceptualize involuntarily childless experiences in dialogue with interactionist and ecological models of disability, to outline a unified and more inclusive eligibility criterion. (shrink)

This letter explores the intricate historical and contemporary links between large language models (LLMs) and cognitive science through the lens of information theory, statistical language models, and socioanthropological linguistic theories. The emergence of LLMs highlights the enduring significance of information‐based and statistical learning theories in understanding human communication. These theories, initially proposed in the mid‐20th century, offered a visionary framework for integrating computational science, social sciences, and humanities, which nonetheless was not fully fulfilled at that time. The subsequent development of (...) sociolinguistics and linguistic anthropology, especially since the 1970s, provided critical perspectives and empirical methods that both challenged and enriched this framework. This letter proposes that two pivotal concepts derived from this development, metapragmatic function and indexicality, offer a fruitful theoretical perspective for integrating the semantic, textual, and pragmatic, contextual dimensions of communication, an amalgamation that contemporary LLMs have yet to fully achieve. The author believes that contemporary cognitive science is at a crucial crossroads, where fostering interdisciplinary dialogues among computational linguistics, social linguistics and linguistic anthropology, and cognitive and social psychology is in particular imperative. Such collaboration is vital to bridge the computational, cognitive, and sociocultural aspects of human communication and human−AI interaction, especially in the era of large language and multimodal models and human‐centric Artificial Intelligence (AI). (shrink)

In the future, full ectogestation – in which artificial placenta technology would be used to carry out the entirety of gestation – could be an alternative to human pregnancy. This article analyzes some underexplored objections to ectogestation which relate to the possibility for new and continuing forms of social oppression. In particular, we examine whether ectogestation could be linked to an unwarranted de-valuing of certain aspects of female reproductive embodiment, or exacerbate objectionable kinds of scrutiny over the reproductive choices of (...) gestating persons. Without discounting the potential benefits of full ectogestation, we conclude that the socially oppressive potential of ectogestation, on top of other concerns, warrants further critical ethical reflection. (shrink)

The Code of the Samurai is a four-hundred-year-old explication of the rules and expectations embodied in Bushido, the Japanese way of the warrior. Bushido has played a major role in shaping the behavior of modern Japanese government, corporations, society.

One who is a Samurai must before all things keep constantly in mind, by day and by night ... the fact that he is going to die.

A general game player automatically learns to play arbitrary new games solely by being told their rules. For this purpose games are specified in the general Game Description Language (GDL), a variant of Datalog with function symbols that uses a few game-specific keywords. A recent extension of basic GDL allows the description of nondeterministic games with any number of players who may have incomplete, asymmetric information. In this paper, we analyse the epistemic structure and expressiveness of this language in terms (...) of modal epistemic logic and prove two main results: (1) The operational semantics of GDL entails that the situation at any stage of a game can be characterised by a multi-agent epistemic (i.e., S5-) model; (2) GDL is sufficiently expressive to model any situation that can be described by a (finite) multi-agent epistemic model. (shrink)