There is increasing interest in how the pupil dynamics of the eye reflect underlying cognitive processes and brain states. Problematic, however, is that pupil changes can be due to non-cognitive factors, for example luminance changes in the environment, accommodation and movement. In this paper we consider how by modeling the response of the pupil in real-world environments we can capture the non-cognitive related changes and remove these to extract a residual signal which is a better index of cognition and performance. (...) Specifically, we utilize sequence measures such as fixation position, duration, saccades, and blink-related information as inputs to a deep recurrent neural network (RNN) model for predicting subsequent pupil diameter. We build and evaluate the model for a task where subjects are watching educational videos and subsequently asked questions based on the content. Compared to commonly-used models for this task, the RNN had the lowest errors rates in predicting subsequent pupil dilation given sequence data. Most importantly was how the model output related to subjects' cognitive performance as assessed by a post-viewing test. Consistent with our hypothesis that the model captures non-cognitive pupil dynamics, we found (1) the model's root-mean square error was less for lower performing subjects than for those having better performance on the post-viewing test, (2) the residuals of the RNN (LSTM) model had the highest correlation with subject post-viewing test scores and (3) the residuals had the highest discriminability (assessed via area under the ROC curve, AUC) for classifying high and low test performers, compared to the true pupil size or the RNN model predictions. This suggests that deep learning sequence models may be good for separating components of pupil responses that are linked to luminance and accommodation from those that are linked to cognition and arousal. (shrink)

Abortion continues to be a moral and ethical dilemma in medicine. While abortions in general have always faced social stigmas, the abortion of fetuses with Down’s syndrome in particular remains the subject of debate across the globe. In India, under the Medical Termination of Pregnancy Act, abortion is legal under prescribed circumstances only till 20 weeks of gestation. Laws for abortion after 20 week of gestation are ill defined. In a recent ruling of the Supreme Court in India, a woman (...) was denied the right to abortion of her 26 week old fetus. With this ruling, India has joined the rest of the world in the debate surrounding abortion laws and the ethics of abortion. (shrink)

Ministry (sharāth/šrt) in the ot is grounded in the nature of God himself. It is grounded in the nature of God’s relationship with Israel, his people. Although the Israelites had many failures, God, with love, elected and called the Israelites—both as individuals and groups—his servants, calling them to serve and to minister to the people, who were themselves ministering, as well as to be servants to the servant people of the Lord. On this basis, this essay exegetically and theologically examines (...) the priestly vocation of the ministering people, or the royal priesthood (mamleket kohănȋm [mt]; hierateuma (lxx]) in Exodus 19:6 and its related texts (Isa 61:6). It demonstrates its theological extension to the nt priestly people basileion hierateuma (1 Pet 2:5, 9–10; cf. Rev 1:6) in order to underline its theological implication for the vocation of the church, the body of Christ, in Africa and beyond. (shrink)