The ability to sustain antibiotic efficacy is directly affected by incentive models aiming to stimulate antibiotic research and development. This paper analyzes the extent to which the models proposed by the Innovative Medicine Initiative-funded research project DRIVE-AB can be expected to support sustainable use, drawing on basic economic theory and the incentives that derive from it. It then discusses the use of minimal safeguards that will be needed to support sustainable use where industry incentives have not been re-aligned with those (...) of public health. (shrink)
On décèle une tension entre deux tendances dans la philosophie aristotélicienne de la praxis : d’une part; une insistance claire sur la spécificité de l’action humaine par rapport à la conduite animale ; d’autre part; la volonté de définir un genre commun pour les différents types d’activités; humaines et animales. Si cette tension peut être surmontée; c’est sans doute en distinguant les différents registres (axiologique; psychologique; éthologique) du discours aristotélicien. C’est aussi en précisant le type de ressemblance qui; à la (...) fois; rapproche et distingue l’homme de l’animal : si la conduite humaine et la conduite animale appartiennent à un genre commun; elles demeurent distinguées par un rapport d’analogie; c’est-à-dire par une différence irréductible. L’analyse éthologique d’Aristote; loin de conduire à une naturalisation du comportement humain; conduit à sa spécification. (shrink)
A recent theory provides a unified cross-linguistic analysis of the interpretations that are assigned to expressions for disjunction, Negative Polarity Items, Free Choice Items, and the non-interrogative uses of wh-phrases in languages such as Mandarin Chinese. If this approach is on the right track, children should be expected to demonstrate similar patterns in the acquisition of these linguistic expressions. Previous research has found that, by age four, children have acquired the knowledge that both the existential indefinite renhe “any” and wh-words (...) in Mandarin Chinese are interpreted as Negative Polarity Items when they are bound by downward entailing operators, but the same expressions are interpreted as Free Choice Items when they are bound by deontic modals or by the Mandarin adverbial quantifier dou “all”. The present study extends this line of research to the Mandarin disjunction word huozhe. A Truth Value Judgment Task was used to investigate the possibility that disjunction phrases that are bound by the adverbial quantifier dou generate a conjunctive interpretation in the grammars of Mandarin-speaking 4-year-old children. The findings confirmed this prediction. We discuss the implications of the findings for linguistic theory and for language learnability. (shrink)
There is a high need for cognition on earthquake risk to improve the public’s risk knowledge and risk awareness, so that they can make right decisions and take quick actions regarding mitigation measures and adjustments. In this study, search engine query data from the Baidu Index were extracted to reveal the information search behaviors of the Chinese public regarding the earthquake risk from 2010 to 2012. The data were also analyzed to discuss the characteristics of need for cognition on a (...) nationwide scale and over the long term. The results showed that graphic representations of need for cognition adhere to a “half-peak pattern” before and after earthquake events and dimensions in psychological distance theory, such as temporal distance, spatial distance, and social distance influence the need for cognition on earthquake risk that was the time and spatial discount effect. The implications for theory and practice regarding risk communication and management are discussed and concluded. (shrink)
The present study will introduce us into a new world of Chinese imagology in the 18th century in France. Different from the negative side of the “sinophobes” such as Montesquieu and François Melon, Sade built a universe of a perfect China in which all crimes were justified. Nevertheless, as a libertine, his point of view was also different from the famous “sinophiles”, La Mothe Le Vayer, Pierre Bayle, Leibniz or Voltaire, for example. China as imagined by Sade was full of (...) infanticide, murder and incest. The pictorial description he uses was largely drawn from the Jesuit literature of that time and some famous travelers’ “relation”, time of the famous theological quarrels about the ritual, easily interested Sade. But, was Sade faithful to these sources or not? Could a libertine moralize about public denunciation? By this foreign image as a mirror, what did he want to explain, taking China as an example, for his own culture? We will give the answers in this article. (shrink)
BackgroundPsychological resilience may reduce the impact of psychological distress to some extent. We aimed to investigate the mental health status of the public during the outbreak of coronavirus disease 2019 and explore the level and related factors of anxiety and depression.MethodsFrom February 8 to March 9, 2020, 3,180 public completed the Zung’s Self-Rating Anxiety Scale for anxiety, Zung’s Self-Rating Depression Scale for depression, the Connor–Davidson resilience scale for psychological resilience, and the Simplified Coping Style Questionnaire for the attitudes and coping (...) styles.ResultsThe number of people with depressive symptoms was 1,303. The number of people with anxiety symptoms was 1,184. The depressed group and anxiety group had less education, more unmarried and younger age, as well as had significant different in SDS total score, SAS total score, CD-RISC total score, and SCSQ score. The binary logistic regression showed that female, strength, and the subscales of active coping style in SCSQ remained protective factors and passive coping style and higher SAS score were risk factors for depression. Optimism in CD-RISC was a protective factor, and passive coping styles and higher SDS score were risk factors for anxiety.LimitationsThis study adopted a cross-sectional design and used self-report questionnaires.ConclusionThe mental health of the public, especially females, the younger and less educational populations, and unmarried individuals, should be given more attention. Individuals with high level of mental resilience and active coping styles would have lower levels of anxiety and depression during the outbreak of COVID-19. (shrink)
Le discours de Plotin sur la phusis ne relève pas à proprement parler de la « science » de la nature. Il s’efforce cependant de caractériser la nature elle-même et son mode de production spécifique dans le Traité 30 -De la nature, de la contemplation et de l’Un . Ce traité recourt, concernant la nature, à une argumentation d’un type spécifique – en l’occurrence, une argumentation négative. On analyse ici la manière dont Plotin définit la production naturelle par un double (...) contraste : en l’opposant à la production technique et à l’action. Il montre ainsi qu’il y a un discours spécifique sur la nature, mais aussi que la méthode la plus appropriée consiste à dire ce qu’elle n’est pas.Comment parler de la nature ? Plotinus’ analysis of phusis doesn’t belong, properly speaking, to « science » of Nature. Nevertheless Plotinus tries to characterize Nature itself in a specific way, that is through a negative argumentation. According to Treatise 30 - On Nature and Contemplation and the One , Nature must be defined in contrast with two kinds of activities : technical production and action. It appears, consequently, that there is a specific discourse about Nature, but also that the most appropriate method consists in telling what Nature is not. (shrink)
El Enfoque de las Capacidades de Sen se distingue en el terreno de la justicia distributiva porque ha intentado establecer criterios evaluativos que superen el atomismo de las teorías utilitaristas. Pero algunos pensadores críticos han señalado que el Enfoque aún mantiene una impronta individualista que limita su alcance a la hora de implementar políticas públicas tendientes a transformar estructuras injustas. Para estos críticos, los conceptos básicos de Sen deben complementarse con una noción de capacidad colectiva o común, irreductible a términos (...) individuales, que permita dar cuenta de los procesos intersubjetivos del desarrollo de la agencia y de la constitución de la identidad personal. En este artículo se analizarán algunas críticas comunitaristas al Enfoque y se intentará postular un candidato plausible a capacidad colectiva, que respete el núcleo vivo de los comentarios y que mantenga los conceptos de capacidad y de agencia centrales en la teoría de Sen. --- “Communities of Meaning as Collective Capabilities. A Communitarian Revision of Amartya Sen’s Theory”. Sen’s Capability Approach it is distinguished in the field of the distributive justice, because It has tried to set evaluatives terms that exceed the atomism of the Utilitarian theories. But some critical thinkers have pointed out that the Approach still keep an individualistic style that restrict its impact at the moment of implementing public policies. For these critics, Sen’s basic concepts must be complemented with the idea of collective capability, irreducible to indivudual terms, that allows to account to the intersubjective process of agency and the personal identity constitution. This paper will attempt to present a plausible candidate to the collective capability, that respects the live core of the communitarian comments and that keeps the capability and agency concepts, which are fundamental in Sen’s theory. (shrink)
Les atomistes de l'Antiquité doivent résoudre le problème suivant : comment expliquer la formation des mondes et des corps composés à partir de corps élémentaires - les atomes - qui n'ont en eux-mêmes aucune propriété cosmogonique? La solution d'Épicure, selon la Lettre à Hérodote, § 45, consiste à adopter une conception subtile de la causalité atomique : les atomes ne sont pas seulement des composants, ou des causes matérielles, mais aussi, par l'intermédiaire d'un processus de sélection spontanée, les véritables agents (...) de la production des mondes et des composés. Ancient atomists face the following difficulty : how can the becoming of worlds and compounds be explained by the elementary bodies, when these - the atoms - do not possess any cosmogonie property? Epicurus ' answer, according to Letter to Herodotus, § 45, is a subtle account of atomic causality : atoms are not only components or material causes, but also, through a spontaneous process of selection, the real agents of the production of worlds and compounds. (shrink)
The principal concern of this paper is with the need of a theoretical shift in economics for analyzing and devising efficient and innovative policy reforms to combat employment insecurity. Mainstream economics is unable to provide appropriate theorizing about economic phenomena, including economic insecurity. Thus, we must turn to economic theories which radically question the dominant paradigm in economics. John Rogers Commons's institutionalist theory accomplishes that. First, the author of this paper outlines the distinctive character of this theory by presenting some (...) of its crucial methodological differences with neoclassical economics. Second, she explains how economic insecurity is conceptualized as an "instituted" process with this theory of institution. A better mastery of this specific school of thought in economics appears to escape the problems met by mainstream economics by proposing a real theoretical alternative for the development of a truly evolutionary, trans-disciplinary and ethical economic theory. (shrink)
In the last lines of Politics VII, 3, Aristotle states that the happy city acts nobly. This implies that the city has a practical life, and that this life has its end in itself. This claim seems to contradict the famous distinction, which has been made elsewhere by Aristotle, between the practical and theoretical lives. It is argued in this paper that there is, here, neither contradiction nor inconsistency in Aristotle’s conception of human action. Some readings, according to which this (...) passage deals with the role of the philosophers in the happy city, are also ruled out. The proposed solution consists in showing that this text refers to a broader conception of action, one that is beyond the sphere of human practical activities: any genuine praxis has its goal in itself, even when it produces external effects. (shrink)
