The scientific, ethical, and policy issues raised by research involving the engraftment of human neural stem cells into the brains of nonhuman primates are explored by an interdisciplinary working group in this Policy Forum. The authors consider the possibility that this research might alter the cognitive capacities of recipient great apes and monkeys, with potential significance for their moral status.

Site‐specific phosphorylation of intermediate filament (IF) proteins on serine and threonine residues leads to alteration of the filament structure, in vitro and in vivo. Protein kinases involved in cell signaling and those activated in mitosis dynamically control spatial and temporal organization of intracellular IF phosphorylation. Thus, IF phosphorylation appears to be one of the most predominant strategies in coordinating intracellular organization of the IF network.

自己決定概念は、患者の自律やインフォームド・コンセント、プライバシー概念等の基礎にあり、生命倫理において核となる重要な概念である。しかし、その歴史的由来について、またその概念の意味するところについて、 これまで本巻のように主題的に扱われることはほとんどなかった。ここでの諸論考は、「自己決定権」や「自律」概念の理解にも大いに役立つはずである。.

This book, Emerson, the Philosophy of Obedience, attempts to trace Emerson who sought to integrate Western and Eastern thoughts to found a new philosophy in the new world. An ardent admirer of Plato, he is at the same time an enthusiast of Eastern philosophy. "Memory," for example, is one of his last lecture series, "Natural Method of Mental Philosophy," in which men are all taken as the halves, because men have aftersight, but not aforesight. Memory is, to Emerson, not only (...) to call forth the past knowledge to the present, but also there is something related to the future, because some past things memorized in the mind are changed into "a possession of its law." This is called "a mutation in quality," by which past things in the mind come into "a possession of its law," obeying the law, just as, in Phaedo, "all the apparent equals strive to attain absolute equality." The Platonic method of Analogy works doubtlessly in Emerson. Men obey this law, because "Nature and [Man] are from one source, and that he, when humble and obedient, is nearer to the source." The mind is such a movement, as he finds that "The mind yields sympathetically to the tendencies or laws which stream through things." The idea of "humble and obedient," or humility and obedience, comes originally from the Chaldæan Oracles and the Heetopades, which have a decisive influence on Emerson, through "the light-armed arrive at the summit," and "the flower of the mind." Because of this profound Eastern thought and ideas, he is called "this student of Eastern philosophy.". (shrink)

This multidisciplinary subject in clinical anthropology was started in April 1996 among 206 students distributed over all Colleges and Schools in the University of Tsukuba with the exception of School of Medical Sciences. After every class students write down their comments on a compulsory attendance slip, and these comments were examined. Female students agreed with the surrogate mothers and homosexuality more than male students. Male students denied childcare by homosexual parents more than female students. Sex selection insemination with the exception (...) for disease prevention was denied by female students significantly more than male students. (shrink)

古代の土俗的にカミ信仰は、中世になると仏教の影響を受けて、教説としての「神道」を形成する。そして近世には儒教の影響を受けて、広く学問と思想の世界を席巻していく。そこには、外来思想の流入に対する。民族の 文化的アイデンティティを追求しようとする日本人の思想的営為があった。カミ信仰の系譜。.

Opera is a performing art in which music plays the leading role, and the acting of singers has a synergistic effect with the music. The mirror neuron system represents the neurophysiological mechanism underlying the coupling of perception and action. Mirror neuron activity is modulated by the appropriateness of actions and clarity of intentions, as well as emotional expression and aesthetic values. Therefore, it would be reasonable to assume that an opera performance induces mirror neuron activity in the audience so that (...) the performer effectively shares an embodied performance with the audience. However, it is uncertain which aspect of opera performance induces mirror neuron activity. It is hypothesized that although auditory stimuli could induce mirror neuron activity, audiovisual perception of stage performance is the primary inducer of mirror neuron activity. To test this hypothesis, this study sought to correlate opera performance with brain activity as measured by electroencephalography in singers while watching an opera performance with sounds or while listening to an aria without visual stimulus. We detected mirror neuron activity by observing that the EEG power in the alpha frequency band was selectively decreased in the frontal-central-parietal area when watching an opera performance. In the auditory condition, however, the alpha-band power did not change relative to the resting condition. This study illustrates that the audiovisual perception of an opera performance engages the mirror neuron system in its audience. (shrink)

In Asian countries, there is a tradition that a rabbit, known as the Moon rabbit, lives on the Moon. Typically, two reasons are mentioned for the origin of this tradition. The first reason is that the color pattern of the lunar surface resembles the shape of a rabbit. The second reason is that both the Moon and rabbits are symbols of fertility, as the Moon appears and disappears (i.e., waxing and waning) cyclically and rabbits are known for their high fertility. (...) Considering the latter reason, is the color pattern of the lunar surface not similar to a rabbit? Here, the similarity between rabbit and the lunar surface pattern was evaluated using seven AI architectures. In the test conducted with Contrastive Language-Image Pre-Training (CLIP), which can classify images based on given words, it was assumed that people frequently observe the Moon in the early evening. Under this condition, the lunar surface pattern was found to be more similar to a rabbit than a face in low-latitude regions, while it could also be classified as a face as the latitude increases. This result is consistent with that the oldest literatures about the Moon rabbit were written in India and that a tradition of seeing a human face in the Moon exists in Europe. In a 1000-class test using seven AI architectures, ConvNeXt and CLIP sometimes classified the lunar surface pattern as a rabbit with relatively high probabilities. Cultures are generated by our attitude to the environment. Both dynamic and static similarities may be essential to induce our imagination. (shrink)

L’article analyse l'implication des collectifs de personnes handicapées et des organisations connexes dans le processus d’élaboration des politiques du handicap au Japon et envisage de nouvelles formes de collaborations pour résoudre les problèmes politiques à venir, en s’appuyant sur l’étude des mouvements sociaux, des interactions stratégiques et de l’action collective coopérative. Il montre, dans un premier temps, comment la question de la dépendance persistante des personnes handicapées vis-à-vis des institutions résidentielles et des membres de leur famille s’est imposée comme un (...) problème fondamental de la politique japonaise du handicap, à la suite de la tragédie de Tsukui Yamayuri-en en 2016. Il retrace ensuite les grandes lignes de la politique japonaise du handicap depuis les années 1960 afin de bien saisir l’origine du problème en relation avec les mouvements des personnes handicapées et de leur famille. Deux exemples de coopération avec des collectifs de personnes handicapées et des organisations affiliées, qui ont eu lieu dans les années 2010, au moment de la ratification de la CDPH, sont présentés. Enfin, des pistes de collaboration plus étroite entre les collectifs de personnes handicapées et les organisations apparentées, en particulier les organisations de parents/familles, sont proposées en vue de favoriser l’émancipation des personnes handicapées vis-à-vis des institutions et de libérer les familles des responsabilités de leur prise en charge. (shrink)

Dai 1-bu. Kindai no tachiage : chishikijintachi -- dai 2-bu. Kindai no katarinaoshi : Watsuji Tetsurō -- dai 3-bu. Nishimura Shigeki bunken kaidai.

本书精辟阐述朝鲜朱子学集大成者-李退溪的主敬哲学的形成、发展过程,思想体系特点及其影响等。.

Hegel, in his work _Philosophy of Right_, defines ownership through three elements: acquisition by occupation, use, and transfer. To own something involves mere acquisition and encompasses its appropriate use and potential transfer to others. Subsequently, the final aspect mentioned was the concept of infinite judgement. The acts of owning and transferring to others are diametrically opposed, and Hegel’s unique logic forcibly connects these opposing concepts. This form of infinite judgement was advocated by the young Hegel during the era of _Phenomenology (...) of Spirit_. There, he stated, “Spirit is a bone”. However, when he later wrote _Science of Logic_ or _Encyclopedia_, the formulation of infinite judgement changed to “Spirit is not something that is bone”. This shift was influenced by Kant. In _Logic_, the discourse advances into syllogism, inferential theory, leading to “Spirit is a bone for such-and-such reasons”. In essence, Hegel binarily connected spirit and bone in his youth and introduced a mediating term in this connection later in his life, establishing inferential links. However, the notion of forcibly connecting opposing concepts remains. Therefore, the statement “Ownership is transfer” represents an infinite judgement while simultaneously signifying syllogism that “I truly own this object if I can transfer it to others”. This contributes to the reasoning that “I and objects can be connected through the intermediary of others”, progressing to the inference that “I and others can be connected through objects”, thereby laying the foundation for society. (shrink)

In the context of the controversies surrounding »globalisation« and In the context of the controversies surrounding »globalisation« and »multiculturality« the comparative study of cultures has the task of aiding intercultural communication and of contributing to the success of intercultural understanding. The model of contrastive cultural comparison discussed here is claimed to have applacibility to every possible study of other countries (»Auslandswissenschaft«) and to be able to provide the Geisteswissenschaften with an intercultural orientation.

3. Benshōhōteki yuibutsuron e no michi.

人間の愛は「不合理」なもの?自由だと勝手に信じている人間が実際には「不自由」なのではないか?なぜ人間は生まれて死ななければならないという「不条理」に遭遇しているのか?そもそも、人間とは何か...?―「 行為」「意志」「存在」の限界をテーマに、行動経済学者や認知科学者、進化論者、実存主義者など多様な分野の学者からカント主義者や急進的フェミニスト、会社員、運動選手、大学生も加わり、楽しく深い広い議論を繰 り広げる。そこから見えてくる人間の姿とは―。.