Results for 'Structured sequence processing'

979 found
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  1.  5
    The Phenomenon of Life.Christopher Alexander & Center for Environmental Structure - 2002
    Contemporary architecture is increasingly grounded in science and mathematics. Architectural discourse has shifted radically from the sometimes disorienting Derridean deconstruction, to engaging scientific terms such as fractals, chaos, complexity, nonlinearity, and evolving systems. That's where the architectural action is -- at least for cutting-edge architects and thinkers -- and every practicing architect and student needs to become conversant with these terms and know what they mean. Unfortunately, the vast majority of architecture faculty are unprepared to explain them to students, not (...)
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  2.  16
    Hierarchical Structure in Sequence Processing: How to Measure It and Determine Its Neural Implementation.Julia Uddén, Mauricio Jesus Dias Martins, Willem Zuidema & W. Tecumseh Fitch - 2020 - Topics in Cognitive Science 12 (3):910-924.
    Spoken language consists of a linear sequence of units, from which the existence of particular underlying hierarchical processing mechanisms is inferred. Uddén et al. use graph theory to provide a framework for describing the possible structural relationships that may underlie a linear output sequence. Being more explicit in defining different structures can help identifying and testing for such structures in AGL experiments, as well as help showing how behavioral and neuroimaging data reveals signatures of hierarchical processing (...)
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  3.  10
    Hierarchical Structure in Sequence Processing: How to Measure It and Determine Its Neural Implementation.Julia Uddén, Mauricio de Jesus Dias Martins, Willem Zuidema & W. Tecumseh Fitch - 2020 - Topics in Cognitive Science 12 (3):910-924.
    Spoken language consists of a linear sequence of units, from which the existence of particular underlying hierarchical processing mechanisms is inferred. Uddén et al. use graph theory to provide a framework for describing the possible structural relationships that may underlie a linear output sequence. Being more explicit in defining different structures can help identifying and testing for such structures in AGL experiments, as well as help showing how behavioral and neuroimaging data reveals signatures of hierarchical processing (...)
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  4.  16
    Structured Sequence Learning: Animal Abilities, Cognitive Operations, and Language Evolution.Christopher I. Petkov & Carel ten Cate - 2020 - Topics in Cognitive Science 12 (3):828-842.
    Human language is a salient example of a neurocognitive system that is specialized to process complex dependencies between sensory events distributed in time, yet how this system evolved and specialized remains unclear. Artificial Grammar Learning (AGL) studies have generated a wealth of insights into how human adults and infants process different types of sequencing dependencies of varying complexity. The AGL paradigm has also been adopted to examine the sequence processing abilities of nonhuman animals. We critically evaluate this growing (...)
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  5.  29
    From evolutionarily conserved frontal regions for sequence processing to human innovations for syntax.Benjamin Wilson & Christopher I. Petkov - 2018 - Interaction Studies. Social Behaviour and Communication in Biological and Artificial Systemsinteraction Studies / Social Behaviour and Communication in Biological and Artificial Systemsinteraction Studies 19 (1-2):318-335.
    Empirical advances have been made in understanding how human language, in its combinatorial complexity and unbounded expressivity, may have evolved from the communication systems present in our evolutionary ancestors. However, a number of cognitive processes and neurobiological mechanisms that support language may not have evolved specifically for communication, but rather from abilities that support perception and cognition more generally. We review recent evidence from comparative behavioural and neurobiological studies on structured sequence learning in human and nonhuman primates. These (...)
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  6.  11
    Finding Hierarchical Structure in Binary Sequences: Evidence from Lindenmayer Grammar Learning.Samuel Schmid, Douglas Saddy & Julie Franck - 2023 - Cognitive Science 47 (1):e13242.
    In this article, we explore the extraction of recursive nested structure in the processing of binary sequences. Our aim was to determine whether humans learn the higher-order regularities of a highly simplified input where only sequential-order information marks the hierarchical structure. To this end, we implemented a sequence generated by the Fibonacci grammar in a serial reaction time task. This deterministic grammar generates aperiodic but self-similar sequences. The combination of these two properties allowed us to evaluate hierarchical learning (...)
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  7. Music and Language Perception: Expectations, Structural Integration, and Cognitive Sequencing.Barbara Tillmann - 2012 - Topics in Cognitive Science 4 (4):568-584.
    Music can be described as sequences of events that are structured in pitch and time. Studying music processing provides insight into how complex event sequences are learned, perceived, and represented by the brain. Given the temporal nature of sound, expectations, structural integration, and cognitive sequencing are central in music perception (i.e., which sounds are most likely to come next and at what moment should they occur?). This paper focuses on similarities in music and language cognition research, showing that (...)
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  8.  60
    Implicit sequence learning: The truth is in the details.Axel Cleeremans & L. JimC)nez - 1998 - In Michael A. Stadler & Peter A. Frensch (eds.), Handbook of Implicit Learning. Newbury Park, CA: Sage.
    Over the past decade, sequence learning has gradually become a central paradigm through which to study implicit learning. In this chapter, we start by briefly summarizing the results obtained with different variants of the sequence learning paradigm. We distinguish three subparadigms in terms of whether the stimulus material is generated either by following a fixed and repeating sequence (e.g., Nissen & Bullemer, 1987), by relying on a complex set of rules from which one can produce several alternative (...)
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  9.  40
    Incremental Sequence Learning.Axel Cleeremans - unknown
    As linguistic competence so clearly illustrates, processing sequences of events is a fundamental aspect of human cognition. For this reason perhaps, sequence learning behavior currently attracts considerable attention in both cognitive psychology and computational theory. In typical sequence learning situations, participants are asked to react to each element of sequentially structured visual sequences of events. An important issue in this context is to determine whether essentially associative processes are sufficient to understand human performance, or whether more (...)
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  10.  39
    Ligand‐induced activation of the insulin receptor: a multi‐step process involving structural changes in both the ligand and the receptor.Colin W. Ward & Michael C. Lawrence - 2009 - Bioessays 31 (4):422-434.
    Current models of insulin binding to the insulin receptor (IR) propose (i) that there are two binding sites on the surface of insulin which engage with two binding sites on the receptor and (ii) that ligand binding involves structural changes in both the ligand and the receptor. Many of the features of insulin binding to its receptor, namely B‐chain helix interactions with the leucine‐rich repeat domain and A‐chain residue interactions with peptide loops from another part of the receptor, are also (...)
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  11.  38
    Sequence and strategy in the secession of the American South.Hudson Meadwell & Lawrence M. Anderson - 2008 - Theory and Society 37 (3):199-227.
    Secession and the civil war that followed are often regarded as having exclusively structural determinants, expressed in political cleavages. From this point of view, these events are explained, variously, by the rise of abolitionism in the North or sectionalism in the Union or some cultural attribute of the South. This focus gets us part of the way in understanding the events that led to secession, the creation of a Southern Confederacy, and civil war, but this interpretation says too little about (...)
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  12.  87
    Theory structure, reduction, and disciplinary integration in biology.Kenneth F. Schaffner - 1993 - Biology and Philosophy 8 (3):319-347.
    This paper examines the nature of theory structure in biology and considers the implications of those theoretical structures for theory reduction. An account of biological theories as interlevel prototypes embodying causal sequences, and related to each other by strong analogies, is presented, and examples from the neurosciences are provided to illustrate these middle-range theories. I then go on to discuss several modifications of Nagel''s classical model of theory reduction, and indicate at what stages in the development of reductions these models (...)
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  13.  6
    Regional Economy Using Hybrid Sequence-to-Sequence-Based Deep Learning Approach.Bo Peng - 2022 - Complexity 2022:1-8.
    In recent times, the role of the regional economy changed significantly under certain conditions of globalization and structural adjustment. The process of changing must be crucial to analyse regional economy and develop the planning of regional economy. Developing economies depend often on industries and country policies. Modern studies tend to participate in important factors in this field such as energy intensity, labour skills, local industries, resources, and local expertise. Furthermore, in this study, to start developing the regional economy and make (...)
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  14.  46
    Applying forward models to sequence learning: A connectionist implementation.Axel Cleeremans - unknown
    The ability to process events in their temporal and sequential context is a fundamental skill made mandatory by constant interaction with a dynamic environment. Sequence learning studies have demonstrated that subjects exhibit detailed — and often implicit — sensitivity to the sequential structure of streams of stimuli. Current connectionist models of performance in the so-called Serial Reaction Time Task (SRT), however, fail to capture the fact that sequence learning can be based not only on sensitivity to the sequential (...)
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  15.  9
    Saving Face and Atrocities: Sequence Expansions and Indirectness in Television Interviews.Majlinda Bregasi - 2020 - Human Studies 43 (1):89-106.
    This article addresses the conversational process taking place during a TV interview in which the contrast shows up between the canonical procedure overseeing the succession and nature of conversational roles and turn-takings in contemporary media contexts and the preservation of an atavistic attitude tied to a traditional culture, Albanian tradition of oda. The discourse in these chambers is a revered phenomenon in the Albanian culture. The interviewee uses the traditional code of oral communication in the oda as a strategy for (...)
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  16.  11
    Structural Basis of Nucleosome Recognition and Modulation.Rajivgandhi Sundaram & Dileep Vasudevan - 2020 - Bioessays 42 (9):1900234.
    Chromatin structure and dynamics regulate key cellular processes such as DNA replication, transcription, repair, remodeling, and gene expression, wherein different protein factors interact with the nucleosomes. In these events, DNA and RNA polymerases, chromatin remodeling enzymes and transcription factors interact with nucleosomes, either in a DNA‐sequence‐specific manner and/or by recognizing different structural features on the nucleosome. The molecular details of the recognition of a nucleosome by different viral proteins, remodeling enzymes, histone post‐translational modifiers, and RNA polymerase II, have been (...)
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  17.  41
    Learnability of Embedded Syntactic Structures Depends on Prosodic Cues.Jutta L. Mueller, Jörg Bahlmann & Angela D. Friederici - 2010 - Cognitive Science 34 (2):338-349.
    The ability to process center‐embedded structures has been claimed to represent a core function of the language faculty. Recently, several studies have investigated the learning of center‐embedded dependencies in artificial grammar settings. Yet some of the results seem to question the learnability of these structures in artificial grammar tasks. Here, we tested under which exposure conditions learning of center‐embedded structures in an artificial grammar is possible. We used naturally spoken syllable sequences and varied the presence of prosodic cues. The results (...)
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  18.  39
    The structure of microbial evolutionary theory.J. Sapp - 2007 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 38 (4):780-795.
    The study of microbial phylogeny and evolution has emerged as an interdisciplinary synthesis, divergent in both methods and concepts from the classical evolutionary biology. The deployment of macromolecular sequencing in microbial classification has provided a deep evolutionary taxonomy hitherto deemed impossible. Microbial phylogenetics has greatly transformed the landscape of evolutionary biology, not only in revitalizing the field in the pursuit of life’s history over billions of years, but also in transcending the structure of thought that has shaped evolutionary theory since (...)
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  19.  42
    Introduction to the Meta-Structures Project: Prospective Applications.Gianfranco Minati - 2012 - World Futures 68 (8):558-574.
    This research project proposes the modeling of collective behaviors such as flocks, industrial districts, and markets. Unlike many other approaches, the aim is to identify ways to recognize, change, and maintain the coherence of collective behaviors, as well as inducing their emergence in configurations of elements that only interact without acquiring properties. The basic assumption is that currently collective behavior is not adequately modeled for the purpose described above when intended as given by sequences of states adopted by the same (...)
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  20.  19
    Challenges in studying genomic structural variant formation mechanisms: The short‐read dilemma and beyond.Megumi Onishi-Seebacher & Jan O. Korbel - 2011 - Bioessays 33 (11):840-850.
    Next‐generation sequencing (NGS) technologies have revolutionised the analysis of genomic structural variants (SVs), providing significant insights into SV de novo formation based on analyses of rearrangement breakpoint junctions. The short DNA reads generated by NGS, however, have also created novel obstacles by biasing the ascertainment of SVs, an aspect that we refer to as the ‘short‐read dilemma’. For example, recent studies have found that SVs are often complex, with SV formation generating large numbers of breakpoints in a single event (multi‐breakpoint (...)
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  21.  28
    Learning Orthographic Structure With Sequential Generative Neural Networks.Alberto Testolin, Ivilin Stoianov, Alessandro Sperduti & Marco Zorzi - 2016 - Cognitive Science 40 (3):579-606.
    Learning the structure of event sequences is a ubiquitous problem in cognition and particularly in language. One possible solution is to learn a probabilistic generative model of sequences that allows making predictions about upcoming events. Though appealing from a neurobiological standpoint, this approach is typically not pursued in connectionist modeling. Here, we investigated a sequential version of the restricted Boltzmann machine, a stochastic recurrent neural network that extracts high-order structure from sensory data through unsupervised generative learning and can encode contextual (...)
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  22.  20
    The Development of Structured Vocalizations in Songbirds and Humans: A Comparative Analysis.Dina Lipkind, Andreea Geambasu & Clara C. Levelt - 2020 - Topics in Cognitive Science 12 (3):894-909.
    Lipkind et al. compare the development of vocal units and sound sequences in sound production in human infants and songbirds. Early in development, infant as well as songbird vocalizations vary along continuous acoustic parameters, with discrete vocal categories and structured vocalizations only emerging later on. This emergence process shows remarkable similarities between infants and zebra finches. Contrary to earlier views, Lipkind et al. suggest that the early development of songbird song (subsong) is more comparable to the phonation stage in (...)
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  23.  55
    Information‐Theoretic Properties of Auditory Sequences Dynamically Influence Expectation and Memory.Kat Agres, Samer Abdallah & Marcus Pearce - 2018 - Cognitive Science 42 (1):43-76.
    A basic function of cognition is to detect regularities in sensory input to facilitate the prediction and recognition of future events. It has been proposed that these implicit expectations arise from an internal predictive coding model, based on knowledge acquired through processes such as statistical learning, but it is unclear how different types of statistical information affect listeners’ memory for auditory stimuli. We used a combination of behavioral and computational methods to investigate memory for non-linguistic auditory sequences. Participants repeatedly heard (...)
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  24.  45
    Event Structure, Punctuality, and When.Sheila Glasbey - 2004 - Natural Language Semantics 12 (2):191-211.
    In this paper, I discuss observations on when given by Sandström (1993) for constructions of the form ‘When A B’, where A and B both describe events (as opposed to states). Sandströ m proposes that for events described in the simple past, the temporal interpretation of such sequences varies according to whether A describes a culminated process (CP)(accomplishment) or a culmination (CULM)(roughly, an achievement). She offers an account of this behaviour based on the claim that culminations denote changes of state (...)
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  25.  13
    Structured event complexes are the primary representation in the human prefrontal cortex.Jordan Grafman - 2020 - Behavioral and Brain Sciences 43.
    Instead of endorsing an all-encompassing view about the influence of abstractions in predictive processing, I suggest that most deliberative thought including complex abstractions, agent actions, and/or perceived environmental sequences are stored in the human prefrontal cortex in the form of structured event complexes.
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  26.  27
    Narrative Structure and Text Structure: Isherwood's "A Meeting by the River," and Muriel Spark's "The Prime of Miss Jean Brodie".John Holloway - 1975 - Critical Inquiry 1 (3):581-604.
    Some recent discussions of narrative structure consider the narrative as a sequence of events, and assume that the structure is what is manifested by the relation between any given event and the event 1, or perhaps the whole sequence from the first event up to the th event in the book. In the present discussion this approach will be modified in two ways. It will be modified, later on, by considering what would be happening if the writer were (...)
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  27.  24
    From the Cellular Standpoint: is DNA Sequence Genetic ‘Information’?Steven S. D. C. Rubin - 2017 - Biosemiotics 10 (2):247-264.
    Constructivist biosemiotics foundations imply the first-person basis of cognition. CBF are developed by the biology of cognition, relational biology, enactive approach, ecology of mind, second order cybernetics, genetic epistemology, gestalt, ecological perception and affordances, and active inference by minimization of free energy. CBF reject the idea of an objective independent reality to be represented by information processing in order to be the fittest. CBF assumes that perception is the behavioral configuration of an object and objects are tokens for eigen-behaviors. (...)
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  28.  15
    Fairly processing rare and common species in multivariate analysis of ecological series. Application to macrobenthic communities from algiers Harbour.C. Manté, J. Claudet & C. Rebzani-Zahaf - 2003 - Acta Biotheoretica 51 (4):277-294.
    Systematic sampling of communities gives rise to large contingency tables summing up possible changes in the assemblages' structure. Such tables are generally analysed by multivariate statistical methods, which are ill-suited for simultaneously analysing rare and common species (Field et al., 1982). In order to separately process species belonging to either of these categories, we propose a statistical method to select common species in a sequence of ecological surveys. It is based on a precise definition of rarity, and depends on (...)
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  29.  19
    The role of secondary structures in the functioning of 3′ untranslated regions of mRNA.Mariya Zhukova, Paul Schedl & Yulii V. Shidlovskii - 2024 - Bioessays 46 (3):2300099.
    Abstract3′ untranslated regions (3′ UTRs) of mRNAs have many functions, including mRNA processing and transport, translational regulation, and mRNA degradation and stability. These different functions require cis‐elements in 3′ UTRs that can be either sequence motifs or RNA structures. Here we review the role of secondary structures in the functioning of 3′ UTRs and discuss some of the trans‐acting factors that interact with these secondary structures in eukaryotic organisms. We propose potential participation of 3′‐UTR secondary structures in cytoplasmic (...)
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  30.  28
    Structural and functional domains on actin.Brett D. Hambly, Julian A. Barden, Masao Miki & Cristobal G. Dos Remedios - 1986 - Bioessays 4 (3):124-128.
    Actin plays several essential roles in cellular processes and is a vital component in the contractile apparatus. To accomplish its many cellular tasks, actin must interact with a wide range of other proteins in addition to self‐assembling into filaments. Characterization of these functional domains and localized binding regions on the actin monomer is therefore an important undertaking. Strategies for elucidating the many interaction sites include X‐ray diffraction, NMR and fluorescence spectroscopy, chemical modification, chemical cross‐linking, protein cleavage, and the study of (...)
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  31. Discourseology of Linguistic Consciousness: Neural Network Modeling of Some Structural and Semantic Relationships.Vitalii Shymko - 2021 - Psycholinguistics 29 (1):193-207.
    Objective. Study of the validity and reliability of the discourse approach for the psycholinguistic understanding of the nature, structure, and features of the linguistic consciousness functioning. -/- Materials & Methods. This paper analyzes artificial neural network models built on the corpus of texts, which were obtained in the process of experimental research of the coronavirus quarantine concept as a new category of linguistic consciousness. The methodology of feedforward artificial neural networks (multilayer perceptron) was used in order to assess the possibility (...)
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  32.  17
    Old Challenges or New Issues? Genetic Health Professionals’ Experiences Obtaining Informed Consent in Diagnostic Genomic Sequencing.Danya F. Vears, Pascal Borry, Julian Savulescu & Julian J. Koplin - 2021 - AJOB Empirical Bioethics 12 (1):12-23.
    Background While integrating genomic sequencing into clinical care carries clear medical benefits, it also raises difficult ethical questions. Compared to traditional sequencing technologies, genomic sequencing and analysis is more likely to identify unsolicited findings (UF) and variants that cannot be classified as benign or disease-causing (variants of uncertain significance; VUS). UF and VUS pose new challenges for genetic health professionals (GHPs) who are obtaining informed consent for genomic sequencing from patients.Methods We conducted semi-structured interviews with 31 GHPs across Europe, (...)
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  33.  20
    Old Challenges or New Issues? Genetic Health Professionals’ Experiences Obtaining Informed Consent in Diagnostic Genomic Sequencing.Danya F. Vears, Pascal Borry, Julian Savulescu & Julian J. Koplin - 2021 - AJOB Empirical Bioethics 12 (1):12-23.
    Background While integrating genomic sequencing into clinical care carries clear medical benefits, it also raises difficult ethical questions. Compared to traditional sequencing technologies, genomic sequencing and analysis is more likely to identify unsolicited findings (UF) and variants that cannot be classified as benign or disease-causing (variants of uncertain significance; VUS). UF and VUS pose new challenges for genetic health professionals (GHPs) who are obtaining informed consent for genomic sequencing from patients.Methods We conducted semi-structured interviews with 31 GHPs across Europe, (...)
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  34.  84
    Can amnesic patients learn without awareness? New evidence comparing deterministic and probabilistic sequence learning.Muriel Vandenberghe, Nicolas Schmidt, Patrick Fery & Axel Cleeremans - 2006 - Neuropsychologia 44 (10):1629-1641.
    Can associative learning take place without awareness? We explore this issue in a sequence learning paradigm with amnesic and control participants, who were simply asked to react to one of four possible stimuli on each trial. Unknown to them, successive stimuli occurred in a sequence. We manipulated the extent to which stimuli followed the sequence in a deterministic manner (noiseless condition) or only probabilistically so (noisy condition). Through this paradigm, we aimed at addressing two central issues: first, (...)
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  35.  41
    On the automaticity of pure perceptual sequence learning.Daphné Coomans, Natacha Deroost, Peter Zeischka & Eric Soetens - 2011 - Consciousness and Cognition 20 (4):1460-1472.
    We investigated the automaticity of implicit sequence learning by varying perceptual load in a pure perceptual sequence learning paradigm. Participants responded to the randomly changing identity of a target, while the irrelevant target location was structured. In Experiment 1, the target was presented under low or high perceptual load during training, whereas testing occurred without load. Unexpectedly, no sequence learning was observed. In Experiment 2, perceptual load was introduced during the test phase to determine whether load (...)
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  36.  15
    Dialogue‐Games: Metacommunication Structures for Natural Language Interaction.James A. Levin & James A. Moore - 1977 - Cognitive Science 1 (4):395-420.
    Our studies of naturally occurring human dialogue have led to the recognition of a class of regularities which characterize impoltant aspects of communication. People appear to interact according to established patterns which span several turns in a dialogue and which recur frequently. These patterns appear to be organized around the goals which the dialogue serves for each participant. Many things which are said later in a dialogue can only be interpreted as pursuit of these goals, established by earlier dialogue.These patterns (...)
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  37.  36
    Prediction‐Based Learning and Processing of Event Knowledge.Ken McRae, Kevin S. Brown & Jeffrey L. Elman - 2021 - Topics in Cognitive Science 13 (1):206-223.
    McRae, Brown and Elman argue against the view that events are structured as frequently‐occurring sequences of world stimuli. They underline the importance of temporal structure defining event types and advance a more complex temporal structure, which allows for some variance in the component elements.
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  38.  14
    Socialization and Process: a Methodological Problem.Colin W. Pritchard - 1982 - Journal of Phenomenological Psychology 13 (2):143-159.
    The basic form of experiencing process as such, then, lies in the apprehension of an object changing through an ordered sequence of states towards an end state. The sequence is grasped in the light of the final state of things which stands in close relation to the central noema of "changing object" in terms of which the phases of the sequence are recognized and related. The central noema is itself an emergent property of the identification of the (...)
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  39.  7
    Sculpture 3D Modeling Method Based on Image Sequence.Xiaofei Liu - 2021 - Complexity 2021:1-13.
    This thesis first introduces the basic principles of model-based image sequence coding technology, then discusses in detail the specific steps in various implementation algorithms, and proposes a basic feature point calibration required in three-dimensional motion and structure estimation. This is a simple and effective solution. Aiming at the monocular video image sequence obtained by only one camera, this paper introduces the 3D model of the sculpture building into the pose tracking framework to provide initial depth information. The whole (...)
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  40.  59
    Event, state, and process in arrow logic.Satoshi Tojo - 1999 - Minds and Machines 9 (1):81-103.
    Artificial agents, which are embedded in a virtual world, need to interpret a sequence of commands given to them adequately, considering the temporal structure for each command. In this paper, we start with the semantics of natural language and classify the temporal structures of various eventualities into such aspectual classes as action, process, and event. In order to formalize these temporal structures, we adopt Arrow Logic. This logic specifies the domain for the valuation of a sentence as an arrow. (...)
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  41.  28
    Intelligent control requires more structure than the theory of event coding provides.Joanna Bryson - 2001 - Behavioral and Brain Sciences 24 (5):878-879.
    That perception and action share abstract representations is a key insight into the organization of intelligence. However, organizing behavior requires additional representations and processes which are not “early” sensing or “late” motion: structures for sequencing actions and arbitrating between behavior subsystems. These systems are described as a supplement to the Theory of Event Coding (TEC).
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  42.  14
    Replication protein A prevents promiscuous annealing between short sequence homologies: Implications for genome integrity.Sarah K. Deng, Huan Chen & Lorraine S. Symington - 2015 - Bioessays 37 (3):305-313.
    Replication protein A (RPA) is the main eukaryotic single‐stranded DNA (ssDNA) binding protein, having essential roles in all DNA metabolic reactions involving ssDNA. RPA binds ssDNA with high affinity, thereby preventing the formation of secondary structures and protecting ssDNA from the action of nucleases, and directly interacts with other DNA processing proteins. Here, we discuss recent results supporting the idea that one function of RPA is to prevent annealing between short repeats that can lead to chromosome rearrangements by microhomology‐mediated (...)
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  43.  4
    Spacers and processing of large ribosomal RNAs in Escherichia coli and mouse cells.D. Schlessinger, R. I. Bolla, R. Sirdeshmukh & J. R. Thomas - 1985 - Bioessays 3 (1):14-18.
    The formation of mature large rRNAs from larger primary transcripts is very different in bacterial and mammalian cells. In both, cotranscription can help to assure the coordinated production of various rRNA species. However, in bacteria, processing is ordered, initiated by cleavages at double‐stranded stems which enclose the mature sequences; several cleavages are required to produce each mature terminus; and the final steps occur in polysomes, apparently linked to continued protein synthesis. In mouse cells, in contrast, cleavages generate nearly all (...)
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  44.  10
    Pre‐mRNA secondary structure and the regulation of splicing.Laurent Balvay, Domenico Libri & Marc Y. Fiszman - 1993 - Bioessays 15 (3):165-169.
    Nuclear pre‐mRNAs must be precisely processed to give rise to mature cytoplasmic mRNAs. This maturation process, known as splicing, involves excision of intron sequences and ligation of the exon sequences. One of the major problems in understanding this process is how splice sites, the sequences which form the boundaries between introns and exons, can be accurately selected. A number of studies have defined conserved sequences within introns which were later shown to interact with small nuclear ribonucleoproteins (snRNPs). However, due to (...)
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  45.  4
    Mind Maps: Processed as Intuitively as Thought? Investigating Late Elementary Students’ Eye-Tracked Visual Behavior Patterns In-Depth.Emmelien Merchie, Sofie Heirweg & Hilde Van Keer - 2022 - Frontiers in Psychology 13.
    In this study, 44 late elementary students’ visual behavior patterns when reading mind maps were investigated, more particularly, the intuitive processing nature of their visual characteristics, reading sequence and presentation mode. Eye-tracked data were investigated by means of static early attention and dynamic educational process mining analysis and combined with learning performance and retrospective interview data. All students seem to struggle with the map’s radial structure during initial reading. Also, the picture’s position in the map diverts students from (...)
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  46.  26
    Cognitive Offloading: Structuring the Environment to Improve Children's Working Memory Task Performance.Ed D. J. Berry, Richard J. Allen, Mark Mon-Williams & Amanda H. Waterman - 2019 - Cognitive Science 43 (8):e12770.
    Research has shown that adults can engage in cognitive offloading, whereby internal processes are offloaded onto the environment to help task performance. Here, we investigate an application of this approach with children, in particular children with poor working memory. Participants were required to remember and recall sequences of colors by placing colored blocks in the correct serial order. In one condition the blocks were arranged to facilitate cognitive offloading (i.e., grouped by color), whereas in the other condition they were arranged (...)
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  47.  45
    Learning to like it: Aesthetic perception of bodies, movements and choreographic structure.Guido Orgs, Nobuhiro Hagura & Patrick Haggard - 2013 - Consciousness and Cognition 22 (2):603-612.
    Appreciating human movement can be a powerful aesthetic experience. We have used apparent biological motion to investigate the aesthetic effects of three levels of movement representation: body postures, movement transitions and choreographic structure. Symmetrical and asymmetrical sequences of apparent movement were created from static postures, and were presented in an artificial grammar learning paradigm. Additionally, “good” continuation of apparent movements was manipulated by changing the number of movement path reversals within a sequence. In an initial exposure phase, one group (...)
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  48.  13
    The role of executive processes in working memory deficits in Parkinson’s Disease.Adrian M. Owen, Edward Necka, Roger R. Barker, Daniel Bor & Aleksandra Gruszka - 2016 - Polish Psychological Bulletin 47 (1):123-130.
    Idiopathic Parkinson’s disease impairs working memory, but the exact nature of this deficit in terms of the underlying cognitive mechanisms is not well understood. In this study patients with mild clinical symptoms of PD were compared with matched healthy control subjects on a computerized battery of tests designed to assess spatial working memory and verbal working memory. In the spatial working memory task, subjects were required to recall a sequence of four locations. The verbal working memory task was methodologically (...)
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  49.  13
    Conceptualising the separation from an abusive partner as a multifactorial, non-linear, dynamic process: A parallel with Newton’s laws of motion.Daniela Di Basilio, Fanny Guglielmucci & Maria Livanou - 2022 - Frontiers in Psychology 13.
    The present study focused on the dynamics and factors underpinning domestic abuse survivors’ decisions to end the abusive relationship. The experiences and opinions of 12 female DA survivors and 18 support workers were examined through in-depth, one-to-one, semi-structured interviews. Hybrid thematic analysis was conducted to retrieve semantic themes and explore relationships among the themes identified and the differences in survivors’ and professionals’ narratives of the separation process. The findings highlighted that separation decisions derived from the joint action of two (...)
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  50.  88
    Fractal Analysis Illuminates the Form of Connectionist Structural Gradualness.Whitney Tabor, Pyeong Whan Cho & Emily Szkudlarek - 2013 - Topics in Cognitive Science 5 (3):634-667.
    We examine two connectionist networks—a fractal learning neural network (FLNN) and a Simple Recurrent Network (SRN)—that are trained to process center-embedded symbol sequences. Previous work provides evidence that connectionist networks trained on infinite-state languages tend to form fractal encodings. Most such work focuses on simple counting recursion cases (e.g., anbn), which are not comparable to the complex recursive patterns seen in natural language syntax. Here, we consider exponential state growth cases (including mirror recursion), describe a new training scheme that seems (...)
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