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Sune Holm [25]Sune Hannibal Holm [1]
  1.  39
    Teleology and Biocentrism.Sune Holm - 2017 - Synthese 194 (4).
    In this paper I examine the connection between accounts of biological teleology and the biocentrist claim that all living beings have a good of their own. I first present the background for biocentrists’ appeal to biological teleology. Then I raise a problem of scope for teleology-based biocentrism and, drawing in part on recent work by Basl and Sandler, I discuss Taylor and Varner’s responses to this problem. I then challenge Basl and Sandler’s own response to the scope problem for its (...)
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  2.  71
    A Right Against Risk-Imposition and the Problem of Paralysis.Sune Holm - 2016 - Ethical Theory and Moral Practice 19 (4):917-930.
    In this paper I examine the prospects for a rights-based approach to the morality of pure risk-imposition. In particular, I discuss a practical challenge to proponents of the thesis that we have a right against being imposed a risk of harm. According to an influential criticism, a right against risk-imposition will rule out all ordinary activities. The paper examines two strategies that rights theorists may follow in response to this “Paralysis Problem”. The first strategy introduces a threshold for when a (...)
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  3.  39
    The Luckless and the Doomed. Contractualism on Justified Risk-Imposition.Sune Holm - 2018 - Ethical Theory and Moral Practice 21 (2):231-244.
    Several authors have argued that contractualism faces a dilemma when it comes to justifying risks generated by socially valuable activities. At the heart of the matter is the question of whether contractualists should adopt an ex post or an ex ante perspective when assessing whether an action or policy is justifiable to each person. In this paper I argue for the modest conclusion that ex post contractualism is a live option notwithstanding recent criticisms raised by proponents of the ex ante (...)
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  4.  39
    Biological Interests, Normative Functions, and Synthetic Biology.Sune Holm - 2012 - Philosophy and Technology 25 (4):525-541.
    In this paper, I discuss the aetiological account of biological interests, developed by Varner, in the context of artefactual organisms envisioned by current research in synthetic biology. In “Sections 2–5”, I present Varner's theory and criticise it for being incapable of ascribing non-derivative interests to artefactual organisms due to their lack of a history of natural selection. In “Sections 6–7”, I develop a new alternative to Varner's account, building on the organisational theory of biological teleology and function. I argue that (...)
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  5.  20
    The Problem of Phantom Functions.Sune Holm - 2017 - Erkenntnis 82 (1):233-241.
    This paper discusses a recent solution to the problem of artifact phantom functions by Beth Preston. A phantom function is a function associated with a kind of artifact that it is structurally incapable of performing. Preston proposes a criterion of artifact proper function according to which phantom functions can be proper functions. This paper argues that Preston’s criterion cannot ground the teleological and normative aspects definitive of proper functions and that the proposed criterion is not consistent with Preston’s account of (...)
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  6.  41
    Disease, Dysfunction, and Synthetic Biology.Sune Holm - 2014 - Journal of Medicine and Philosophy 39 (4):329-345.
    Theorists analyzing the concept of disease on the basis of the notion of dysfunction consider disease to be dysfunction requiring. More specifically, dysfunction-requiring theories of disease claim that for an individual to be diseased certain biological facts about it must be the case. Disease is not wholly a matter of evaluative attitudes. In this paper, I consider the dysfunction-requiring component of Wakefield’s hybrid account of disease in light of the artifactual organisms envisioned by current research in synthetic biology. In particular, (...)
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  7.  20
    Is Synthetic Biology Mechanical Biology?Sune Holm - 2015 - History and Philosophy of the Life Sciences 37 (4):413-429.
    A widespread and influential characterization of synthetic biology emphasizes that synthetic biology is the application of engineering principles to living systems. Furthermore, there is a strong tendency to express the engineering approach to organisms in terms of what seems to be an ontological claim: organisms are machines. In the paper I investigate the ontological and heuristic significance of the machine analogy in synthetic biology. I argue that the use of the machine analogy and the aim of producing rationally designed organisms (...)
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  8.  25
    Organism and Artifact: Proper Functions in Paley Organisms.Sune Holm - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4b):706-713.
    In this paper I assess the explanatory powers of theories of function in the context of products that may result from synthetic biology. The aim is not to develop a new theory of functions, but to assess existing theories of function in relation to a new kind of biological and artifactual entity that might be produced in the not-too-distant future by means of synthetic biology. The paper thus investigates how to conceive of the functional nature of living systems that are (...)
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  9.  31
    Organism, Machine, Artifact: The Conceptual and Normative Challenges of Synthetic Biology.Sune Holm & Russell Powell - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):627-631.
    Synthetic biology is an emerging discipline that aims to apply rational engineering principles in the design and creation of organisms that are exquisitely tailored to human ends. The creation of artificial life raises conceptual, methodological and normative challenges that are ripe for philosophical investigation. This special issue examines the defining concepts and methods of synthetic biology, details the contours of the organism–artifact distinction, situates the products of synthetic biology vis-à-vis this conceptual typology and against historical human manipulation of the living (...)
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  10.  28
    Precaution, Threshold Risk and Public Deliberation.Sune Holm - 2019 - Bioethics 33 (2):254-260.
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  11.  18
    The Fairness in Algorithmic Fairness.Sune Holm - forthcoming - Res Publica:1-17.
    With the increasing use of algorithms in high-stakes areas such as criminal justice and health has come a significant concern about the fairness of prediction-based decision procedures. In this article I argue that a prominent class of mathematically incompatible performance parity criteria can all be understood as applications of John Broome’s account of fairness as the proportional satisfaction of claims. On this interpretation these criteria do not disagree on what it means for an algorithm to be fair. Rather they express (...)
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  12.  29
    Health as a Property of Engineered Living Systems.Sune Holm - 2013 - Bioethics 27 (8):419-425.
    This article considers naturalistic analyses of the concepts of health and disease in light of the possibility of constructing novel living systems. The article begins by introducing the vision of synthetic biology as the application of engineering principles to the construction of biological systems, the main analyses of the concepts of health and disease, and the standard theories of function in artefacts and organisms. The article then suggests that reflection on the possibility of artefactual organisms amounts to a challenge to (...)
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  13.  8
    Handle with Care: Assessing Performance Measures of Medical AI for Shared Clinical Decision‐Making.Sune Holm - 2022 - Bioethics 36 (2):178-186.
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  14.  65
    Constitutive Relevance in Interlevel Experiments.Maria Serban & Sune Holm - 2020 - British Journal for the Philosophy of Science 71 (2):697-725.
    One reason for the popularity of Craver’s mutual manipulability account of constitutive relevance is that it seems to make good sense of the experimental practices and constitutive reasoning in the life sciences. Two recent papers propose a theoretical alternative to in light of several important conceptual objections. Their alternative approach, the no de-coupling account, conceives of constitution as a dependence relation that once postulated provides the best explanation of the impossibility of breaking the common cause coupling of a macro-level mechanism (...)
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  15.  22
    The Scientific Aspirations of Synthetic Biology and the Need for Analytic Ethics.Sune Holm - 2012 - Ethics, Policy and Environment 15 (1):25 - 28.
    Ethics, Policy & Environment, Volume 15, Issue 1, Page 25-28, March 2012.
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  16.  32
    New Directions for the Precautionary Principle: Introduction.Sune Holm & Daniel Steel - 2019 - Ethics, Policy and Environment 22 (1):1-2.
    Volume 22, Issue 1, March 2019, Page 1-2.
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  17.  29
    Jessica Riskin, The Restless Clock: A History of the Centuries - Long Argument Over What Makes Living Things Tick. Chicago: The University of Chicago Press, 2016, Pp. 544, ISBN 978-0-226- 30292-8. $40.00. [REVIEW]Sune Holm - 2018 - History and Philosophy of the Life Sciences 40 (4):60.
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  18.  4
    Handle with Care: Assessing Performance Measures of Medical AI for Shared Clinical Decision‐Making.Sune Holm - 2022 - Wiley: Bioethics 36 (2):178-186.
    Bioethics, Volume 36, Issue 2, Page 178-186, February 2022.
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  19.  4
    Designer Biology: The Ethics of Intensively Engineering Biological and Ecological Systems.Immaculada de Melo Martin, Valentina Urbanek, David Frank, William Kabasenche, Nicholas Agar, S. Matthew Liao, Anders Sandberg, Rebecca Roache, Allen Thompson, Stephen Jackson, Donald S. Maier, Nicole Hassoun, Benjamin Hale, Sune Holm & Scott Simmons (eds.) - 2013 - Lexington Books.
    Designer Biology: The Ethics of Intensively Engineering Biological and Ecological Systems consists of thirteen chapters that address the ethical issues raised by technological intervention and design across a broad range of biological and ecological systems. Among the technologies addressed are geoengineering, human enhancement, sex selection, genetic modification, and synthetic biology.
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  20.  1
    Philosophical Perspectives on the Engineering Approach in Biology: Living Machines?Sune Holm & Maria Serban (eds.) - 2020 - Routledge.
    Philosophical Perspectives on the Engineering Approach in Biology provides a philosophical examination of what has been called the most powerful metaphor in biology: The machine metaphor. The chapters collected in this volume discuss the idea that living systems can be understood through the lens of engineering methods and machine metaphors from both historical, theoretical, and practical perspectives. In their contributions the authors examine questions about scientific explanation and methodology, the interrelationship between science and engineering, and the impact that the use (...)
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  21.  16
    Alvaro Moreno and Matteo Mossio. 2015. Biological Autonomy: A Philosophical and Theoretical Enquiry.Louisa Jane Holt & Sune Holm - 2017 - Theoria. An International Journal for Theory, History and Foundations of Science 32 (3):392.
    Review of Alvaro Moreno and Matteo Mossio. 2015. Biological autonomy: a philosophical and theoretical enquiry.
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  22.  11
    Deciding in the Dark: The Precautionary Principle and the Regulation of Synthetic Biology.Sune Holm - 2019 - Ethics, Policy and Environment 22 (1):61-71.
    ABSTRACTAccording to Bedau and Triant decision-makers will be substantially ignorant about the consequences of their candidate choices when making decisions about synthetic biology. Bedau and Triant characterize decisions under such circumstances as decisions in the dark. They then argue that when making decisions in the dark, decision-makers should not appeal to the Precautionary Principle because this principle does not sufficiently accommodate important features of ‘deciding and acting virtuously’. In the paper, I point out that it is unclear how to understand (...)
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  23.  16
    Teleological Organisation.Sune Holm & John Basl - 2017 - Synthese 194 (4):1027-1029.
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  24.  14
    Bridging Bioethics and Biology.Sune Holm - 2016 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 55:133-136.
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  25. Synthetic Biology and Biological Interests.Sune Hannibal Holm - forthcoming - Philosophy and Technology.
     
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  26.  2
    Biological Autonomy: A Philosophical and Theoretical Enquiry. [REVIEW]Louisa Jane Holt & Sune Holm - 2017 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 32 (3):392-395.
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