14 found
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  1.  17
    Rethinking the Role of the Nervous System: Lessons From the Hydra Holobiont.Alexander V. Klimovich & Thomas C. G. Bosch - 2018 - Bioessays 40 (9):1800060.
    Here we evaluate our current understanding of the function of the nervous system in Hydra, a non‐bilaterian animal which is among the first metazoans that contain neurons. We highlight growing evidence that the nervous system, with its rich repertoire of neuropeptides, is involved in controlling resident beneficial microbes. We also review observations that indicate that microbes affect the animal's behavior by directly interfering with neuronal receptors. These findings provide new insight into the original role of the nervous system, and suggest (...)
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  2.  19
    The Microbiome Mediates Environmental Effects on Aging.Brett B. Finlay, Sven Pettersson, Melissa K. Melby & Thomas C. G. Bosch - 2019 - Bioessays 41 (10):1800257.
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  3.  38
    Why bacteria matter in animal development and evolution.Sebastian Fraune & Thomas C. G. Bosch - 2010 - Bioessays 32 (7):571-580.
  4.  6
    Multidisciplinary Approaches to Exploring Human–Microbiome Interactions.Thomas C. G. Bosch - 2019 - Bioessays 41 (10):1900130.
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  5.  40
    Hydra and the evolution of stem cells.Thomas C. G. Bosch - 2009 - Bioessays 31 (4):478-486.
  6.  9
    Evolutionary “Experiments” in Symbiosis: The Study of Model Animals Provides Insights into the Mechanisms Underlying the Diversity of Host–Microbe Interactions.Thomas C. G. Bosch, Karen Guillemin & Margaret McFall-Ngai - 2019 - Bioessays 41 (10):1800256.
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  7.  7
    Compagen, a comparative genomics platform for early branching metazoan animals, reveals early origins of genes regulating stem‐cell differentiation.Georg Hemmrich & Thomas C. G. Bosch - 2008 - Bioessays 30 (10):1010-1018.
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  8.  18
    Understanding why we age and how: Evolutionary biology meets different model organisms and multi-level omics.Eric Gilson & Thomas C. G. Bosch - 2016 - Bioessays 38 (6):494-497.
    The conference explored an extraordinary diversity of aging strategies in organisms ranging from short‐lived species to “immortal” animals and plants. Research on the biological processes of aging is at the brink of a revolution with respect to our understanding of its underlying mechanisms as well as our ability to prevent and cure a wide variety of age‐related pathologies.
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  9.  19
    Polyps, peptides and patterning.Thomas C. G. Bosch & Toshitaka Fujisawa - 2001 - Bioessays 23 (5):420-427.
  10.  35
    How do environmental factors influence life cycles and development? An experimental framework for early-diverging metazoans.Thomas C. G. Bosch, Maja Adamska, René Augustin, Tomislav Domazet-Loso, Sylvain Foret, Sebastian Fraune, Noriko Funayama, Juris Grasis, Mayuko Hamada, Masayuki Hatta, Bert Hobmayer, Kotoe Kawai, Alexander Klimovich, Michael Manuel, Chuya Shinzato, Uli Technau, Seungshic Yum & David J. Miller - 2014 - Bioessays 36 (12):1185-1194.
  11. Hydra and the hair follicle – An unconventional comparative biology approach to exploring the human holobiont.Marta B. Lousada, Tim Lachnit, Janin Edelkamp, Ralf Paus & Thomas C. G. Bosch - 2022 - Bioessays 44 (5):2100233.
    The microbiome of human hair follicles (HFs) has emerged as an important player in different HF and skin pathologies, yet awaits in-depth exploration. This raises questions regarding the tightly linked interactions between host environment, nutrient dependency of host-associated microbes, microbial metabolism, microbe-microbe interactions and host immunity. The use of simple model systems facilitates addressing generally important questions and testing overarching, therapeutically relevant principles that likely transcend obvious interspecies differences. Here, we evaluate the potential of the freshwater polyp Hydra, to dissect (...)
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  12.  12
    Control of asymmetric cell divisions: will cnidarians provide an answer?Thomas C. G. Bosch - 2004 - Bioessays 26 (9):929-931.
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  13.  10
    BioEssays 4/2009.Thomas C. G. Bosch - 2009 - Bioessays 31 (4).
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  14.  2
    BioEssays 10∕2019.Thomas C. G. Bosch - 2019 - Bioessays 41 (10):1970101.
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