Using medical advances to enhance human athletic, aesthetic, and cognitive performance, rather than to treat disease, has been controversial. Little is known about physicians? experiences, views, and attitudes in this regard. We surveyed a national sample of physicians to determine how often they prescribe enhancements, their views on using medicine for enhancement, and whether they would be willing to prescribe a series of potential interventions that might be considered enhancements. We find that many physicians occasionally prescribe enhancements, but doctors hold (...) nuanced and ambiguous views of these issues. Most express concerns about the potential effects of enhancements on social equity, yet many also believe specific enhancements that are safe and effective should be available but not covered by insurance. These apparently contradictory views might reflect inherent tensions between the values of equity and liberty, which could make crafting coherent social policies on medical enhancements challenging. [Supplementary materials are available for this article. Go to the publisher's online edition of American Journal of Bioethics for the following free supplemental resource(s): An additional table (Table 5) referred to on p. 5]. (shrink)

In this article we describe our approach to understanding wrongdoing in medical research and practice, which involves the statistical analysis of coded data from a large set of published cases. We focus on understanding the environmental factors that predict the kind and the severity of wrongdoing in medicine. Through review of empirical and theoretical literature, consultation with experts, the application of criminological theory, and ongoing analysis of our first 60 cases, we hypothesize that 10 contextual features of the medical environment (...) (including financial rewards, oversight failures, and patients belonging to vulnerable groups) may contribute to professional wrongdoing. We define each variable, examine data supporting our hypothesis, and present a brief case synopsis from our study that illustrates the potential influence of the variable. Finally, we discuss limitations of the resulting framework and directions for future research. (shrink)

Hunger continues to be one of humanity's greatest challenges despite the existence of a more-than-adequate global food supply equal to 2,800 kilocalories for every person every day. In measuring progress, policy-makers and concerned citizens across the globe rely on information supplied by the Food and Agriculture Organization , an agency of the United Nations. In 2010 the FAO reported that in the wake of the 2007–2008 food-price spikes and global economic crisis, the number of people experiencing hunger worldwide since 2005–2007 (...) had increased by 150 million, rising above 1 billion in 2009. However, in its State of Food Insecurity in the World 2012 the FAO presented new estimates, having revamped its methods and reinterpreted its hunger data back to 1990. The revised numbers for the period 1990–1992 to 2010–2012 reverse the trend to a steadily falling one. Based on the FAO's new calculations, extreme undernourishment peaked in 1990 at a record-breaking one billion, followed by a significant decline through 2006, when progress stalled but did not reverse. (shrink)

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

Written and directed by Paul-Thomas Anderson, Punch-Drunk Love exposes the complexity and kitsch superficialities of masculine gender constructions. The following essay provides a summary of gender theory in order to uncover and better understand the film's post-patriarchal vision of masculinity.

The conventional approach to international development by civil society—that is, the installation of “Western” programs and institutions by “Western” groups in “underdeveloped” regions—has remained largely unchanged since global poverty reduction, whether for political or social justice motivations, gained prominence in public discourse after World War II. Yet poverty rates, literacy, life expectancy, and unemployment in one of the poorest regions of the world, sub-Saharan Africa, has remained the same if not worsened since the 1970s . And, still, the great Development (...) Project continues: Problems in under-resourced areas are identified by well-meaning people from well-resourced areas, proposals to solve those problems are crafted by project managers and submitted to government and nongovernmental agencies, and successful projects are implemented by other well-meaning people who, for the most part, honestly want to make a difference. This is the system in which Priya seems to .. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Questioning the Motives of Habituated Action:Burke and Bourdieu on PracticeDana AndersonThe British official's habit, in the Empire's remotest spots, of dressing for dinner is in effect the transporting of an idol, the vessel of a motive that has its sanctuary in the homeland.—Kenneth Burke, A Grammar of Motives, 44In his recent Kenneth Burke and the Conversation after Philosophy, Timothy Crusius locates Burke in the context of "PostPhilosophical" thought (...) by describing Burke's expansive Dramatistic project as a praxis—as a program encompassing "any act whatsoever, including symbolic action (i.e., expression, whether artistic or discursive), in behalf of a better life." When praxis is conceived broadly as a dialectical perspective on human action—that agents and structures interact in mutually determining ways—the term becomes, in fact, an accurate summary of the entire Burkean corpus: "If we understand it as Burke does," Crusius continues, "all that he wrote is praxis" (1999, 198). This panoramic scope of Burke's dialectical inquiry is certainly one reason it remains rhetorical theory's perhaps most flexible and productive framework for considering human action; the Dramatistic pentad and its ratios for discussing the attribution of motive continue to invite theoretical "ways of placement" as multifaceted as human motives themselves.Speaking of Burke's work in terms of praxis, however, at least in the term's contemporary critical usage,1 raises a question regarding a cognate concept that the idea of praxis entails: in what sense is Burke's pentadic grammar of action equipped to consider the habituated actions characteristic of human practice?Practice, as a conceptual descendant of Marxian praxis, retains a connection with what Marx called "human sensuous activity" (1968, 28-30).2 In its most general sense, practice refers to the regular and repeated activities of agents that, in their quotidian enactment, dialectically [End Page 255] constitute an agent's sense of self and of reality in relation to external conditions of existence. While the activities of agents will tend to reify the dominant external conditions in which agents act, these external conditions are nonetheless open to change inasmuch as the evolving practices of individuals might come to challenge them. This perspective of the determined, yet determining nature of human practice is aptly summarized in The German Ideology, where Marx and Engels famously argue that "circumstances make men just as much as men make circumstances" (2000, 189).3 As Michel de Certeau's seminal studies of practice have demonstrated (de Certeau 1984; de Certeau, Giard, and Mayol 1998), the power of this relationship of mutual constitution between individuals and their worlds of external circumstances owes directly to the banality of the actions through which such constitution is accomplished—actions ranging from the way bread is served in a given household, to the way cosmetics are purchased in department stores, to the general "ways of operating" in urban spaces, including simply walking in one's own neighborhood (de Certeau, Giard, and Mayol 1998; Mayol 1998, 7-13). As Judith Butler very poignantly summarizes, it is through precisely such "embodied rituals of everydayness," however "taken-for-granted" they may be, that "a given culture produces and sustains belief in its own 'obviousness' " (1999, 113-14).The constitutive dynamics of such practical actions should surely figure prominently into any conception of Burke's work as praxis. Indeed, this dynamic is already implicit in the fact that, for Burke, it is only through the possibility of mutually transforming both ourselves and our worlds through actions material and symbolic that we might begin to move toward a better life. But while Dramatism and practice rest on similar perspectives of the dialectically constitutive nature of human action, several aspects of the grammar through which Burke investigates motive might appear to limit, or even to preclude, the Dramatistic examination of practice as a kind of motivated action. More specifically, Burke's consistent "anti-Behaviorist" emphasis on the conscious or purposive nature of action questions the extent to which Dramatism can account for the dispositional and habituated actions characteristic of practice, actions for which agents would be least able to articulate conscious purposes. To cast the issue in the context of my epigraph above... (shrink)

Knowledge and its Limits presents a systematic new conception of knowledge as a kind of mental stage sensitive to the knower's environment. It makes a major contribution to the debate between externalist and internalist philosophies of mind, and breaks radically with the epistemological tradition of analyzing knowledge in terms of true belief. The theory casts new light on such philosophical problems as scepticism, evidence, probability and assertion, realism and anti-realism, and the limits of what can be known. The arguments are (...) illustrated by rigorous models based on epistemic logic and probability theory. The result is a new way of doing epistemology and a notable contribution to the philosophy of mind. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Diacritics 29.4 (1999) 40-57 [Access article in PDF] Bogeyman: Benedict Anderson's "Derivative" Discourse Andrew Parker Between life and death, nationalism has as its own proper space the experience of haunting. There is no nationalism without some ghost. -Jacques Derrida, "Onto-Theology of National-Humanism" Writing a mere decade ago about Benedict Anderson's Imagined Communities, Timothy Brennan noted that "with the exception of some recent sociological works which use (...) literary theories, it is rare in English to see 'nation-ness' talked about as an imaginative vision--as a topic worthy of full fictional realization.... Even in the underrepresented branch of Third World English studies, one is likely to find discussions of race and colonialism, but not the 'nation' as such" [47]. If these sentences appear astonishing today--if over the past ten years we seem to have done little else but regard the nation as an imaginative construction--our sense of surprise may help to register how rapidly and profoundly Anderson's work has transformed the nature of literary and cultural studies. Viewing the modern nation primarily as an anthropological rather than political category, one that has less inherently to do with ideologies than with kinship, gender, and religion, Anderson argues in Imagined Communities for the irreducibility of material-cultural practices (what he memorably termed "print-capitalism") in creating and sustaining the "imagined community" of a nation whose citizens maintain "deep attachments" to each other in the absence of face-to-face contact: "the members of even the smallest nation will never know most of their fellow-members, meet them, or even hear of them, yet in the minds of each lives the image of their communion" [6]. Part of what makes such communities national, Anderson suggests, is a shared experience of simultaneity modeled on the spatio-temporal organization of newspapers and novels, for "these forms provided the technical means for 're-presenting' the kind of imagined community that is the nation" by furnishing their reader-consumers with a "complex gloss on the word 'meanwhile'" [25]. The "old-fashioned novel" especially, through its distinctive structures of address and omniscient point of view, becomes in this schema a "device" for generating a sociologically complex world populated by characters who, even though they "may be largely unaware of each other," nevertheless move together "calendrically through homogeneous, empty time"--a world, in short, that may be considered "a precise analogue of the idea of the nation, which also is conceived as a solid community moving steadily up (or down) history" [25-26]. As Jonathan Culler aptly summarizes in his contribution to this issue, Anderson thus takes the novel to be "a precondition for the nation" [24], "a formal condition of imagining the nation--a structural condition of possibility" [37]. Such strong emphasis on the novel as "a force for imagining the communities that are nations" certainly helps to explain why Imagined Communities so swiftly and pervasively became doxa in literary study--even if, as Culler elaborates, some of Anderson's readers have mistaken his argument for a stronger if less defensible [End Page 40] version that sees the novel as "a force in shaping or legitimating the nation" [37].While Anderson's analogy between novel and nation has been put by literary critics to a multitude of creative uses, what has been acknowledged much less commonly is that his literary interests are by no means exhausted by the paradigm for which he is best known. 1 The very title of his most recent book is, significantly as we shall see, a translated quotation from a novel, and he returns repeatedly for insights into the politics of literary form not only to Walter Benjamin but to certain exemplary "nationalist" novelists, José Rizal and Pramoedya Ananta Toer first and foremost. Where The Spectre of Comparisons is unusual in containing chapter-length readings of literary works (several of them reprinted from the earlier Language and Power), Imagined Communities was no stranger to detailed discussions of fiction. We may be struck, in fact, by the extent to which Anderson's theoretical and historical studies locate themselves persistently over time with reference to "literature... (shrink)

This is not your psychoanalyst's unconscious.

In this paper, we consider recent attempts to metaphysically explain agentive modality in terms of conditionals. We suggest that the best recent accounts face counterexamples, and more worryingly, they take some agentive modality for granted. In particular, the ability to perform basic actions features as a primitive in these theories. While it is perfectly acceptable for a semantics of agentive modal claims to take some modality for granted in getting the extension of action claims correct, a metaphysical explanation of agentive (...) modality cannot, at least not in the way that conditional approaches to agentive modality do. We argue that this problem was present even in the classical conditional analysis. By a pessimistic induction, we suggest that, probably, no conditional approach to agentive modality will succeed. (shrink)

Knepper criticizes existing efforts in the philosophy of religion for being out of step with, and therefore useless to, the academic study of religion, then forwards a new program for philosophy of religion that is in step with, and therefore useful to, the academic study of religion.

According to the Fragmentation Analysis, epistemic akrasia is a state of conflict between beliefs formed by the linguistic and non-linguistic belief-formation systems, and epistemic akrasia is irrational because it is a state of conflict between beliefs so formed. I argue that there are cases of higher-order epistemic akrasia, where both beliefs are formed by the linguistic belief-formation system. Because the Fragmentation Analysis cannot accommodate this possibility, the Fragmentation Analysis is incorrect. I consider three objections to the possibility of higher-order epistemic (...) akrasia. Along the way, I offer a revision of the Fragmentation Analysis that can allow for the possibility of higher-order akrasia while avoiding the problems I point out for the original view. (shrink)

In this global introduction to philosophy of religion you begin not with a single tradition, but with religious philosophies from East Asia, South Asia, West Africa, and Native North America, alongside the classical Abrahamic and modern European traditions. Matching this diversity of traditions, chapters are organized around questions that acknowledge there is no single understanding of any god or ultimate reality. Instead you approach six different traditions of philosophizing about religion by asking questions about the journeys of both the self (...) and the cosmos such as "What is my path?" and "Where did the cosmos come from?" Accompanied by introductory materials and an extensive glossary, each chapter includes learning objectives, questions for discussion, and suggested primary and secondary sources. The categories of religion and philosophy are interrogated throughout. Equipped with study tools and universal questions about the self and the cosmos, Philosophies of Religion: A Global and Critical Introduction shows you how to philosophize about religions around the world. (shrink)

Skeptical theism is a family of responses to the evidential problem of evil. What unifies this family is two general claims. First, that even if God were to exist, we shouldn’t expect to see God’s reasons for permitting the suffering we observe. Second, the previous claim entails the failure of a variety of arguments from evil against the existence of God. In this essay, we identify three particular articulations of skeptical theism—three different ways of “filling in” those two claims—and describes (...) their role in responding to evidential arguments of evil due to William Rowe and Paul Draper. But skeptical theism has been subject to a variety of criticisms, several of which raise interesting issues and puzzles not just in philosophy of religion but other areas of philosophy as well. Consequently, we discuss some of these criticisms, partly with an eye to bringing out the connections between skeptical theism and current topics in mainstream philosophy. Finally, we conclude by situating skeptical theism within our own distinctive methodology for evaluating world views, what we call “worldview theory versioning.”. (shrink)

Second-order logic and modal logic are both, separately, major topics of philosophical discussion. Although both have been criticized by Quine and others, increasingly many philosophers find their strictures uncompelling, and regard both branches of logic as valuable resources for the articulation and investigation of significant issues in logical metaphysics and elsewhere. One might therefore expect some combination of the two sorts of logic to constitute a natural and more comprehensive background logic for metaphysics. So it is somewhat surprising to find (...) that philosophical discussion of secondorder modal logic is almost totally absent, despite the pioneering contribution of Barcan. (shrink)

Christian ethical imagination was always tempered by various social prejudices prevalent in local contexts. Particularly during modernity and subsequently through colonial expansion, the role of race and caste became central to the expansion of Christianity through missionary activity. A closer scrutiny of colonial missionary Christianity clearly suggests the significance of racialised worldview shaping theological and ethical paradigms. In particular contexts, such racialised imagination underpinned and gave credence to other forms of social prejudices, such as caste in South Asia. Through a (...) post-colonial lens, I examine the role of race and caste in shaping Christian ethical frameworks and articulate the rationale for ‘decolonising’ the modern foundations of Christian ethics in pursuit of racial justice in our contemporary society. (shrink)

The paper explores the main competing interpretations of Aristotle's view of the relation between happiness and external goods in the Nicomachean Ethics. On the basis of a careful analysis of what Aristotle says in the Nicomachean Ethics (and other works such as the Eudemian Ethics, Politics, Rhetoric, etc.) it is argued that it is likely that Aristotle takes at least some external goods to be actual constituents of happiness provided that (1) they are accompanied by virtuous activity and (2) the (...) agent enjoying and using those external goods does so in ways compatible with the continuous aim of acting virtuously. (shrink)

On method, discursive logics, and epistemology -- Questions of medieval discursive practice -- From the middle ages to the (w)hole of Utopia -- Kepler, his Dream, and the analysis and pattern of thought -- Campanella and Bacon: concerning structures of mind -- The masculine birth of time -- Cyrano and the experimental discourse -- The myth of sun and moon -- The difficulty of writing -- Crusoe rights his story -- Gulliver's critique of Euclid -- Emergence, consolidation, and dominance of (...) a discourse. (shrink)

Jecker and colleagues open (2024) a critical and needed dialogue about the ethics of international conferencing. In particular, they focus on proposing a set of principles in selecting the location...

This is the first single volume to offer a comprehensive and systematic account of British and American aesthetics from the early eighteenth century to the late twentieth century.

Things in common: an introduction -- Life -- Specters -- Subscendence -- Species -- Kindness.

The chapter argues that a model‐building methodology like that widespread in contemporary natural and social science already plays a significant role in philosophy. One neglected form of progress in philosophy over the past fifty years has been the development of better and better formal models of significant phenomena. Examples are given from both philosophy of language and epistemology. Philosophy can do still better in the future by applying model‐building methods more systematically and self‐consciously, with consequent readjustments to its methodology. Although (...) it is neither likely nor desirable for model‐building to become the sole or even main philosophical method, its use enhances the power and reliability of philosophical thinking. (shrink)

This volume offers readers a unique and comprehensive overview of theoretical perspectives on "the sublime," the singular aesthetic response elicited by phenomena that move viewers by transcending and overwhelming them. The book consists of an editor's introduction and fifteen chapters written from a variety of disciplinary perspectives. Part One examines philosophical approaches advanced historically to account for the phenomenon, beginning with Longinus, moving through eighteenth and nineteenth century writers in Britain, France, and Germany, and concluding with developments in contemporary continental (...) philosophy. Part Two explores the sublime with respect to particular disciplines and areas of study, including Dutch literature, early modern America, the environment, religion, British Romanticism, the fine arts, and architecture. Each chapter is both accessible for nonspecialists and offers an original contribution to its respective field of inquiry. (shrink)

The author argues that all forms of life are interconnected and that no being, construct, or object can exist independently from the ecological entanglement, nor does "nature" exist as an entity separate from the uglier or more synthetic elements of life. Realizing this interconnectedness is what the author calls the ecological thought. He investigates the philosophical, political, and aesthetic implications of this interconnectedness.

Lewisian reference magnetism about linguistic content determination [Lewis 1983 has been defended in recent work by Weatherson [2003] and Sider [2009], among others. Two advantages claimed for the view are its capacity to make sense of systematic error in speakers' use of their words, and its capacity to distinguish between verbal and substantive disagreements. Our understanding of both error and disagreement is linked to the role of usage and first order intuitions in semantics and in linguistic theory more generally. I (...) argue, partially on the basis of these more general considerations, that reference magnetism delivers implausible results. Specifically, I argue that the proponent of reference magnetism maintains her analysis of genuinely systematic error at the cost of an empirically unjustifiable error theory regarding ordinary usage. In response, I describe an alternative view of content determination—MUMPS, or Meaning is Use Minus Pragmatics—which is not committed to such error theories. Despite this advantage, MUMPS has high prima facie costs. On such a view, there is a great deal of variation in linguistic meaning across speakers and times. As a result, a large number of seemingly mistaken claims are analysed as expressing true propositions. Correspondingly, a large number of seemingly substantive disagreements are analysed as terminological. However, I argue that these consequences are not as costly as they seem. Despite appearances, MUMPS is consistent with objective, metaphysically realist adjudication of disagreements, even in cases where meanings are not shared and where both parties to a dispute speak truly. MUMPS thus allows for a more nuanced understanding of linguistic usage, change, and variation, without imposing a commitment to any form of metaphysical anti-realism. (shrink)

The philosophical relevance of experimental psychology is hard to dispute. Much more controversial is the so‐called negative program's critique of armchair philosophical methodology, in particular the reliance on ‘intuitions’ about thought experiments. This chapter responds to that critique. It argues that, since the negative program has been forced to extend the category of intuition to ordinary judgments about real‐life cases, the critique is in immediate danger of generating into global scepticism, because all human judgments turn out to depend on intuitions. (...) Recently, some proponents of the negative program have tried to demarcate the target of their critique more narrowly. However, their attempts are still far too indiscriminate, and over‐generate scepticism. Nevertheless, once experimental philosophy has refined its own methodology, it may contribute to the refinement of the methodology of mainstream philosophy, by filtering out the effects of cognitive bias, although it offers no prospect of doing without judgments on real or imaginary cases. (shrink)

Discussions of sexual ethics often focus on the wrong of treating another as a mere object instead of as a person worthy of respect. On this view, the task of sexual ethics becomes putting the other’s subjectivity above their status as erotic object so as to avoid the harms of objectification. Ward and Anderson argue that such a view disregards the crucial, moral role that erotic objecthood plays in sexual encounters. Important moral features of intimacy are disclosed through the (...) experience of being an erotic object for another, as well as in perceiving another as an erotic object. Drawing on phenomenology, especially the insights of Simone de Beauvoir, Ward and Anderson argue that erotic encounters are shaped by the human condition of ambiguity, where being an object for others is intertwined with bodily agency. Because sexual agency is complex in this way, theories of sexual ethics and responsibility must widen their focus beyond transparent communication and authoritative expressions of will. (shrink)