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Tudor M. Baetu [15]Tudor Baetu [5]
  1.  60
    Filling in the Mechanistic Details: Two-Variable Experiments as Tests for Constitutive Relevance. [REVIEW]Tudor Baetu - 2012 - European Journal for Philosophy of Science 2 (3):337-353.
    This paper provides an account of the experimental conditions required for establishing whether correlating or causally relevant factors are constitutive components of a mechanism connecting input (start) and output (finish) conditions. I argue that two-variable experiments, where both the initial conditions and a component postulated by the mechanism are simultaneously manipulated on an independent basis, are usually required in order to differentiate between correlating or causally relevant factors and constitutively relevant ones. Based on a typical research project molecular biology, a (...)
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  2.  20
    The Completeness of Mechanistic Explanations.Tudor M. Baetu - 2015 - Philosophy of Science 82 (5):775-786.
    The paper discusses methodological guidelines for evaluating mechanistic explanations. According to current accounts, a satisfactory mechanistic explanation should include all of the relevant features of the mechanism, its component entities and activities, and their properties and organization, as well as exhibit productive continuity. It is not specified, however, how this kind of mechanistic completeness can be demonstrated. I argue that parameter sufficiency inferences based on mathematical model simulations provide a way of determining whether a mechanism capable of producing the phenomenon (...)
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  3. Mechanism Schemas and the Relationship Between Biological Theories.Tudor M. Baetu - 2011 - In Phyllis McKay Illari Federica Russo (ed.), Causality in the Sciences. Oxford University Press.
  4.  24
    From Interventions to Mechanistic Explanations.Tudor M. Baetu - 2016 - Synthese 193 (10).
    An important strategy in the discovery of biological mechanisms involves the piecing together of experimental results from interventions. However, if mechanisms are investigated by means of ideal interventions, as defined by James Woodward and others, then the kind of information revealed is insufficient to discriminate between modular and non-modular causal contributions. Ideal interventions suffice for constructing webs of causal dependencies that can be used to make some predictions about experimental outcomes, but tell us little about how causally relevant factors are (...)
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  5.  17
    Models and the Mosaic of Scientific Knowledge. The Case of Immunology.Tudor M. Baetu - 2014 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 45 (1):49-56.
    A survey of models in immunology is conducted and distinct kinds of models are characterized based on whether models are material or conceptual, the distinctiveness of their epistemic purpose, and the criteria for evaluating the goodness of a model relative to its intended purpose. I argue that the diversity of models in interdisciplinary fields such as immunology reflects the fact that information about the phenomena of interest is gathered from different sources using multiple methods of investigation. To each model is (...)
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  6.  1
    Models and the Mosaic of Scientific Knowledge. The Case of Immunology.Tudor Baetu - 2014 - Studies in History and Philosophy of Science Part C 45 (1):49-56.
    A survey of models in immunology is conducted and distinct kinds of models are characterized based on whether models are material or conceptual, the distinctiveness of their epistemic purpose, and the criteria for evaluating the goodness of a model relative to its intended purpose. I argue that the diversity of models in interdisciplinary fields such as immunology reflects the fact that information about the phenomena of interest is gathered from different sources using multiple methods of investigation. To each model is (...)
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  7. Models and the Mosaic of Scientific Knowledge. The Case of Immunology.Tudor M. Baetu - 2013 - Studies in History and Philosophy of Biological and Biomedical Sciences 45:49-56.
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  8.  32
    The Referential Convergence of Gene Concepts Based on Classical and Molecular Analyses.Tudor M. Baetu - 2010 - International Studies in the Philosophy of Science 24 (4):411-427.
    Kenneth Waters and Marcel Weber argue that the joint use of distinct gene concepts and the transfer of knowledge between classical and molecular analyses in contemporary scientific practice is possible because classical and molecular concepts of the gene refer to overlapping chromosomal segments and the DNA sequences associated with these segments. However, while pointing in the direction of coreference, both authors also agree that there is a considerable divergence between the actual sequences that count as genes in classical genetics and (...)
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  9.  75
    Emergence, Therefore Antireductionism? A Critique of Emergent Antireductionism.Tudor Baetu - 2012 - Biology and Philosophy 27 (3):433-448.
    Emergent antireductionism in biological sciences states that even though all living cells and organisms are composed of molecules, molecular wholes are characterized by emergent properties that can only be understood from the perspective of cellular and organismal levels of composition. Thus, an emergence claim (molecular wholes are characterized by emergent properties) is thought to support a form of antireductionism (properties of higher-level molecular wholes can only be understood by taking into account concepts, theories and explanations dealing with higher-level entities). I (...)
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  10.  49
    Mechanistic Constraints on Evolutionary Outcomes.Tudor M. Baetu - 2012 - Philosophy of Science 79 (2):276-294.
  11.  15
    Chance, Experimental Reproducibility, and Mechanistic Regularity.Tudor M. Baetu - 2013 - International Studies in the Philosophy of Science 27 (3):253-271.
    Examples from the sciences showing that mechanisms do not always succeed in producing the phenomena for which they are responsible have led some authors to conclude that the regularity requirement can be eliminated from characterizations of mechanisms. In this article, I challenge this conclusion and argue that a minimal form of regularity is inextricably embedded in examples of elucidated mechanisms that have been shown to be causally responsible for phenomena. Examples of mechanistic explanations from the sciences involve mechanisms that have (...)
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  12.  1
    Genes After the Human Genome Project.Tudor M. Baetu - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (1):191-201.
  13.  2
    On Pain Experience, Multidisciplinary Integration and the Level-Laden Conception of Science.Tudor M. Baetu - forthcoming - Synthese:1-20.
    Multidisciplinary models aggregating ‘lower-level’ biological and ‘higher-level’ psychological and social determinants of a phenomenon raise a puzzle. How is the interaction between the physical, the psychological and the social conceptualized and explained? Using biopsychosocial models of pain as an illustration, I argue that these models are in fact level-neutral compilations of empirical findings about correlated and causally relevant factors, and as such they neither assume, nor entail a conceptual or ontological stratification into levels of description, explanation or reality. If inter-level (...)
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  14.  44
    Defining Species: A Multi-Level Approach.Tudor Baetu - 2012 - Acta Biotheoretica 60 (3):239-255.
    Different concepts define species at the pattern-level grouping of organisms into discrete clusters, the level of the processes operating within and between populations leading to the formation and maintenance of these clusters, or the level of the inner-organismic genetic and molecular mechanisms that contribute to species cohesion or promote speciation. I argue that, unlike single-level approaches, a multi-level framework takes into account the complex sequences of cause-effect reinforcements leading to the formation and maintenance of various patterns, and allows for revisions (...)
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  15.  39
    Genes After the Human Genome Project.Tudor M. Baetu - 2012 - Studies in History and Philosophy of Science Part C 43 (1):191-201.
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  16.  36
    A Defense of Syntax-Based Gene Concepts in Postgenomics: Genes as Modular Subroutines in the Master Genomic Program.Tudor M. Baetu - 2011 - Philosophy of Science 78 (5):712-723.
    The purpose of this article is to update and defend syntax-based gene concepts. I show how syntax-based concepts can and have been extended to accommodate complex cases of processing and gene expression regulation. In response to difficult cases and causal parity objections, I argue that a syntax-based approach fleshes out a deflationary concept defining genes as genomic sequences and organizational features of the genome contributing to a phenotype. These organizational features are an important part of accepted molecular explanations, provide the (...)
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  17.  13
    Model Thinking in the Life Sciences: Complexity in the Making. [REVIEW]Tudor M. Baetu, Ann-Sophie Barwich, Daniel Brooks, Sébastien Dutreuil & Pierre-Luc Germain - 2013 - Biological Theory 8 (1):121-124.
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  18.  1
    Genes After the Human Genome Project.Tudor M. Baetu - 2012 - Studies in History and Philosophy of Biological and Biomedical Sciences 43 (1):191-201.
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  19. Model Thinking in the Life Sciences: Complexity in the Making: Second European Advanced Seminar in the Philosophy of the Life Sciences,“In Vivo, Ex Vivo, in Vitro, in Silico: Models in the Life Sciences” Hermance, Switzerland, 10–14 September 2012.(Meeting Report). [REVIEW]Tudor M. Baetu, Ann-Sophie Barwich, Daniel Brooks, Sébastien Dutreuil & Pierre-Luc Germain - 2013 - Biological Theory 8 (1):121 - 124.
     
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  20. When Is a Mechanistic Explanation Satisfactory? Reductionism and Antireductionism in the Context of Mechanistic Explanations.Tudor Băetu - 2015 - In Iulian D. Toader, Gabriel Sandu & Ilie Pȃrvu (eds.), Romanian Studies in Philosophy of Science. Springer Verlag.
     
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