The aim of synthetic biology is to rationally design devices, systems, and organisms with desired innovative and useful functions (Slusarczyk, Lin, and Weiss 2012). To achieve this aim, synthetic biology uses a concept similar to engineering sciences: well-characterized and standardized modular biological building blocks are reassembled in a systematic and rational manner to generate complex devices and systems with a predicted function. In the past, molecular biological research in combination with intense work in new research areas like systems biology and (...) functional genomics revealed a large inventory of multifaceted modular biological parts that are now in the toolboxes of synthetic biologists. Due to .. (shrink)

Die in diesem Buch vorgestellten Theorien der Herrschaft zielen auf die Sozialbeziehungen und deren Legitimität. Sie beginnen mit Niccolo Machiavelli, in dessen Denken der Staat eine ähnlich zentrale Position einnimmt wie in den Vertragstheorien des neuzeitlichen Naturrechts von Thomas Hobbes und Jean-Jacques Rousseau. Von Bedeutung wird dabei die politische Machbarkeit der staatlichen Institutionen, die Karl Marx und Friedrich Engels, aber auch Max Horkheimer und Theodor W. Adorno kritisch hinterfragen. Zuvor haben Max Weber und Robert Michels den charismatischen beziehungsweise den (...) faschistischen Führerstaat mit Nachdruck propagiert. Insgesamt eine von der kritischen Politischen Philosophie her motivierte Ideengeschichte. (shrink)

Max Weber (1864-1920), generally known as a founder of modern social science, was concerned with political affairs throughout his life. The texts in this edition span his career and include his early inaugural lecture The Nation State and Economic Policy, Suffrage and Democracy in Germany, Parliament and Government in Germany under a New Political Order, Socialism, The Profession and Vocation of Politics, and an excerpt from his essay The Situation of Constitutional Democracy in Russia, as well as other shorter (...) writings. Together they illustrate the development of his thinking on the fate of Germany and the nature of politics in the modern western state in an age of cultural 'disenchantment'. The introduction discusses the central themes of Weber's political thought, and a chronology, notes and an annotated bibliography place him in his political and intellectual context. (shrink)

This unique volume gathers Weber's writings on a broad array of themes, from the nature of work, to the political culture of democracy, to the uniqueness of the West, to the character of the family and race relations, to the role of science and the fate of ethical action in the modern world. Gathers Weber’s writings in a comprehensive collection, organized by topic. Rejuvenates a central, pivotal theme of Weberian thought: "How do we live?" and "How can we (...) live in the industrial society?” Connects Weber’s writings to contemporary issues through modern essays and editorial introductions. (shrink)

Zuerst im 2CV, dann im umgebauten VW-Bus: Das Zürcher Fotografenpaar Margrit und Ernst Baumann, 1929 bzw. 1928 geboren, begann in den 1950er-Jahren rund um den Erdball zu reisen. Ihre Fotografien publizierten sie in Zeitschriften und Zeitungen wie Stern, Neue Zürcher Zeitung oder Das gelbe Heft und brachten so die Welt in die Wohnzimmer. Kosmopolitan und neugierig kamen sie zu Motiven mit Seltenheitswert: Farbporträts von Che Guevara gehören ebenso dazu wie Reportagen über die letzten Kopfjäger im ecuadorianischen Urwald. Ein Schwerpunkt dieser (...) reich bebilderten Doppelmonografie ist ihre Reise entlang der “Panamericana” 1957-1959, die Süd- und Nordamerika verbindet. Sie fotografierten Reportagen, Porträts und Landschaftsbilder und drehten den wohl ersten Farbfilm über den legendären Verkehrsweg. Dieser Film und ein Filporträt über die beiden Fotografen sind dem Buch auf DVD beigefügt. Das Buch präsentiert Funde aus ihrem Fotoarchiv - viele Bilder erstmals im Originalausschnitt - sowie Publikationen in Zeitschriften. Der Historiker und Schriftsteller Wilfried Meichtry erzählt vom ereignisreichen Leben des Paars, das sich zeitlebens als journalistische Handwerker verstanden hat. Der Fotohistoriker Markus Schürpf ordnet ihr Werk in die Foto- und Pressegeschichte ein, Nadine Olonetzky verfasst Begleittexte zu den Bildern. Eine Entdeckung in der Schweizer Fotogeschichte. (shrink)

Max Weber and Michael Foucault are among the most controversial and fascinating thinkers of our century. This book is the first to jointly analyse them in detail, and to make effective links between their lives and work; it coincides with a substantial resurgence of interest in their writings. The author's exciting interpretative approach reveals a new dimension in reading the work of Foucault and Weber; it will be invaluable to students and those researching in sociology and philosophy.

In this article we give a unifying approach to the theory of fundamental sequences and their related Hardy hierarchies of number-theoretic functions and we show the equivalence of the new approach with the classical one.

Philosophers and social scientists will welcome this highly original discussion of Max Weber's analysis of the objectivity of social science. Guy Oakes traces the vital connection between Weber's methodology and the work of philosopher Heinrich Rickert, reconstructing Rickert's notoriously difficult concepts in order to isolate the important, and until now poorly understood, roots of problems in Weber's own work.Guy Oakes teaches social philosophy at Monmouth College and sociology at the New School for Social Research.

In this rapid commentary, a mini-review is given of the present state-of-knowledge regarding the etiology and epidemiology of the new coronavirus 2019-nCoV and the risks for developing Acute respiratory distress syndrome. The available knowledge on the viral genomics, molecular biology and pathogenicity of viruses of the Coronaviridae family and other Nidovirales, forms a helpful template for understanding the present pandemic outbreak. However, important questions remain unanswered about the underlying mechanism causing the very high case fatality ratios and mechanisms regarding severe (...) reactions like ARDS, fatal cardiac and renal failures, associated with a number of important comorbidity factors. Immunological reactions to lung alveoles in particular in late phase ARDS in SARS-like CoV diseases, so far may not have received enough attention. Finally a shortlist of questions for high priority further research is suggested. (shrink)

In this paper we present a theoretical hybrid framework for ethical decision making, drawing upon Emmanuel Levinas’ view on ethics as “first philosophy”, as an inherent infinite responsibility for the other. The pivotal concept in this framework is an appeal to a heightened sense of personal responsibility of the moral actor to provide the ethical context within which conventional approaches to applied business ethics could be engaged. Max Weber’s method of reconciling absolutism and relativism in ethical decision making is (...) adopted to provide the synergy between personal responsibility and contextual realities, forging a coherent framework. The paper concludes by discussing ways that business could make way for the flourishing of ethics of responsibility in individuals. (shrink)

Weber-Fechner Law states that the perceived intensity is proportional to the logarithm of the stimulus. Recent experiments suggest that this law also holds true for perception of numerosity. Therefore, the use of a logarithmic scale for the quantification of the perceived intensity may also depend on how the cognitive apparatus processes information. If Weber-Fechner law is the result of natural selection, then the logarithmic scale should be better, in some sense, than other biologically feasible scales. We consider the (...) minimization of the relative error as the target of natural selection and we provide a formal proof that the logarithmic scale minimizes the maximal relative error. (shrink)

Since their inception, the Perspectives in Logic and Lecture Notes in Logic series have published seminal works by leading logicians. Many of the original books in the series have been unavailable for years, but they are now in print once again. This volume, the fifteenth publication in the Lecture Notes in Logic series, collects papers presented at the symposium 'Reflections on the Foundations of Mathematics' held in celebration of Solomon Feferman's 70th birthday at Stanford University, California in 1988. Feferman has (...) shaped the field of foundational research for nearly half a century. These papers reflect his broad interests as well as his approach to foundational research, which emphasizes the solution of mathematical and philosophical problems. There are four sections, covering proof theoretic analysis, logic and computation, applicative and self-applicative theories, and philosophy of modern mathematical and logic thought. (shrink)

Lighting upon Weber as a history student in the late 1950s led to all round engagement with his work to the present day, beginning with rationality and bureaucracy, passing through appreciation of his synoptic vision of modernity, and arguing for the continuing relevance of his rationalization thesis. This emphasis on Weber’s contribution to understanding the course of modernity led in the 1990s to pointing out that his approach to epochal shift provides the basis for understanding the global age. (...) The ever-developing nature of his thought can be further illustrated in his studies of China. (shrink)

English summary: Does pastoral care require ethical competence in order to fulfil its task properly? And, conversely, to what extent does ethical reflection require feedback from pastoral experience in order to remain true to life and of practical relevance? Wilfried Sturm examines the way hospital pastors deal with ethical challenges and conflict situations in neonatal clinics and enquires into the insights that can be gained from them for the relationship of pastoral care and ethics. German description: Braucht Seelsorge ethische (...) Kompetenz, um ihrem Auftrag gerecht zu werden? Inwiefern bedarf umgekehrt die ethische Reflexion der Ruckkopplung an seelsorgerliche Erfahrung, um lebensnah und praxisrelevant zu bleiben? Wilfried Sturm untersucht den Umgang von Klinikseelsorgerinnen und -seelsorgern mit ethischen Herausforderungen und Konfliktsituationen in der Fruh- und Neugeborenenmedizin und fragt, welche Einsichten sich daraus fur das Verhaltnis von Seelsorge und Ethik gewinnen lassen. (shrink)

Wilfried Sieg. Calculations by Man and Machine: Conceptual Analysis.

Wilfried Sieg and John Byrnes. AnModel for Parallel Computation: Gandy's Thesis.

David Hilbert was one of the great mathematicians who expounded the centrality of their subject in human thought. In this collection of essays, Wilfried Sieg frames Hilbert's foundational work, from 1890 to 1939, in a comprehensive way and integrates it with modern proof theoretic investigations.

While Weber’s distinction between ‘ideal’ and ‘material’ interests is one of the most enduring aspects of his theoretical legacy, it has been subjected to little critical commentary. In this article, we revisit the theoretical legacy of interest-based explanation in social theory, with an eye to clarifying Weber’s place in this tradition. We then reconsider extant critical commentary on the ideal/material interest distinction, noting the primarily Parsonian rendering of Weber and the unproductive allegiance to ‘generic need’ readings of (...) Weber’s action theory. We reconstruct the basis of the ideal/material interest distinction in the work of Rudolph von Ihering and provide a sounder basis for its analytic role in Weber’s ‘grand’ project. (shrink)

First Published in 2004. Routledge is an imprint of Taylor & Francis, an informa company.

Using the concept of notations for infinitary derivations we give an explanation of Takeuti's reduction steps on finite derivations (used in his consistency proof for Π1 1-CA) in terms of the more perspicious infinitary approach from [BS88].

The Hygiene Hypothesis has been recognized as an important cornerstone to explain the sudden increase in the prevalence of asthma and allergic diseases in modernized culture. The recent epidemic of allergic diseases is in contrast with the gradual implementation of Homo sapiens sapiens to the present-day forms of civilization. This civilization forms a gradual process with cumulative effects on the human immune system, which co-developed with parasitic and commensal Helminths. The clinical manifestation of this epidemic, however, became only visible in (...) the second half of the twentieth century. In order to explain these clinical effects in terms of the underlying IgE-mediated reactions to innocuous environmental antigens, the low biodiversity of antigens in the domestic environment plays a pivotal role. The skewing of antigen exposure as a cumulative effect of reducing biodiversity in the immediate human environment as well as in changing food habits, provides a sufficient and parsimonious explanation for the rise in allergic diseases in a highly developed and helminth-free modernized culture. Socio-economic tendencies that incline towards a further reduction of environmental biodiversity may provide serious concern for future health. This article explains that the “Hygiene Hypothesis”, the “Old Friends Hypothesis”, and the “Skewed Antigen Exposure Hypothesis” are required to more fully explain the rise of allergy in modern societies. (shrink)