In the eyes of some of its critics, disjunctivism fails to support adequately the key claim that a particular hallucination might be indistinguishable from a certain kind of veridical perception despite the two states having nothing other than this in common. Scott Sturgeon, for example, has complained that disjunctivism ‘‘offers no positive story about hallucination at all’’ (2000: 11) and therefore ‘‘simply takes [indistinguishability] for granted’’ (2000: 12). So according to Sturgeon, what the disjunctivist needs to provide is a (...) plausible explanation of just how two mental states which have no common component might be indistinguishable for their subject and this in turn will require the telling of a positive story about hallucination. This is the goal of the present essay. (shrink)

The dominant unspoken philosophical basis of medical care in the United States is a form of Cartesian reductionism that views the body as a machine and medical professionals as technicians whose job is to repair that machine. The purpose of this paper is to advocate for an alternative philosophy of medicine based on the concept of healing relationships between clinicians and patients. This is accomplished first by exploring the ethical and philosophical work of Pellegrino and Thomasma and then by connecting (...) Martin Buber's philosophical work on the nature of relationships to an empirically derived model of the medical healing relationship. The Healing Relationship Model was developed by the authors through qualitative analysis of interviews of physicians and patients. Clinician-patient healing relationships are a special form of what Buber calls I-Thou relationships, characterized by dialog and mutuality, but a mutuality limited by the inherent asymmetry of the clinician-patient relationship. The Healing Relationship Model identifies three processes necessary for such relationships to develop and be sustained: Valuing, Appreciating Power and Abiding. We explore in detail how these processes, as well as other components of the model resonate with Buber's concepts of I-Thou and I-It relationships. The resulting combined conceptual model illuminates the wholeness underlying the dual roles of clinicians as healers and providers of technical biomedicine. On the basis of our analysis, we argue that health care should be focused on healing, with I-Thou relationships at its core. (shrink)

Motivation: There is an ongoing search for definitive and reliable biomarkers to forecast or predict imminent seizure onset, but to date most research has been limited to EEG with sampling rates <1,000 Hz. High-frequency oscillations have gained acceptance as an indicator of epileptic tissue, but few have investigated the temporal properties of HFOs or their potential role as a predictor in seizure prediction. Here we evaluate time-varying trends in preictal HFO rates as a potential biomarker of seizure prediction.Methods: HFOs were (...) identified for all interictal and preictal periods with a validated automated detector in 27 patients who underwent intracranial EEG monitoring. We used LASSO logistic regression with several features of the HFO rate to distinguish preictal from interictal periods in each individual. We then tested these models with held-out data and evaluated their performance with the area-under-the-curve of their receiver-operating curve. Finally, we assessed the significance of these results using non-parametric statistical tests.Results: There was variability in the ability of HFOs to discern preictal from interictal states across our cohort. We identified a subset of 10 patients in whom the presence of the preictal state could be successfully predicted better than chance. For some of these individuals, average AUC in the held-out data reached higher than 0.80, which suggests that HFO rates can significantly differentiate preictal and interictal periods for certain patients.Significance: These findings show that temporal trends in HFO rate can predict the preictal state better than random chance in some individuals. Such promising results indicate that future prediction efforts would benefit from the inclusion of high-frequency information in their predictive models and technological architecture. (shrink)

Book Symposium on Cheryl Misak's Cambridge Pragmatism: From Peirce and James to Ramsey and WittgensteinCheryl Misak's Cambridge Pragmatism is posited on the thought that the link between belief and action is a pragmatist hallmark. It is this central commitment that Misak sees running through the work of the towering figures of the two Cambridges—C.S. Peirce, William James, Bertrand Russell, Frank Ramsey, and Ludwig Wittgenstein. It is on this basis that Misak holds that these figures can be termed 'pragmatists.' My (...) objective in this comment is to make two arguments in light of Misak's hallmark thesis. The first argument is that if Misak is right, then the term 'Cambridge... (shrink)

This book offers a philosophy for error-prone humans trying to understand messy systems in the real world.

To say ‘mysticism versus philosophy’ in the context of Islamic civilization means something far different from what it has come to signify in the West, where many philosophers have looked upon mysticism as the abandonment of any attempt to reconcile religious data with intelligent thought. Certainly the Muslim mystics and philosophers sometimes display a certain mutual opposition and antagonism, but never does their relationship even approach incompatibility.

Most philosophical accounts of emergence are incompatible with reduction. Most scientists regard a system property as emergent relative to properties of the system's parts if it depends upon their mode of organization--a view consistent with reduction. Emergence can be analyzed as a failure of aggregativity--a state in which "the whole is nothing more than the sum of its parts." Aggregativity requires four conditions, giving tools for analyzing modes of organization. Differently met for different decompositions of the system, and in different (...) degrees, these conditions provide powerful evaluation criteria for choosing decompositions, and heuristics for detecting biases of vulgar reductionisms. This analysis of emergence is compatible with reduction. (shrink)

Methodological reductionists practice ‘wannabe reductionism’. They claim that one should pursue reductionism, but never propose how. I integrate two strains in prior work to do so. Three kinds of activities are pursued as “reductionist”. “Successional reduction” and inter-level mechanistic explanation are legitimate and powerful strategies. Eliminativism is generally ill-conceived. Specific problem-solving heuristics for constructing inter-level mechanistic explanations show why and when they can provide powerful and fruitful tools and insights, but sometimes lead to erroneous results. I show how traditional metaphysical (...) approaches fail to engage how science is done. The methods used do so, and support a pragmatic and non-eliminativist realism. (shrink)

Most philosophical accounts of emergence are incompatible with reduction. Most scientists regard a system property as emergent relative to properties of its parts if it depends upon their mode of organization-a view consistent with reduction. Emergence is a failure of aggregativity, in which ``the whole is nothing more than the sum of its parts''. Aggregativity requires four conditions, giving powerful tools for analyzing modes of organization. Differently met for different decompositions of the system, and in different degrees, the structural conditions (...) can provide evaluation criteria for choosing decompositions, ``natural kinds'', and detecting functional localization fallacies, approximations, and various biases of vulgar reductionisms. This analysis of emergence and use of these conditions as heuristics is consistent with a broader reductionistic methodology. (shrink)

William C. Gentry was both an academic philosopher, perfectly willing to engage in the philosophical 'conversations' of the written word and, more importantly, a true philosopher, in the Platonic and Socratic style. Engaging with those around him in discourse, in live conversations, which are the vehicle of actual philosophical inquiry and discovery. These essays are the product of those conversations. Gentry's thoughts consisted of investigations into the deepest and most profound questions of human nature, ethics, and knowledge. This volume (...) is a tribute both to his role as a teacher and philosopher. As a teacher, friend, and colleague, Gentry was the epitome of the philosopher: questioning, exploring, critiquing, discovering. (shrink)

Richard Levins’ distinction between aggregate, composed and evolved systems acquires new significance as we recognize the importance of mechanistic explanation. Criteria for aggregativity provide limiting cases for absence of organization, so through their failure, can provide rich detectors for organizational properties. I explore the use of failures of aggregativity for the analysis of mechanistic systems in diverse contexts. Aggregativity appears theoretically desireable, but we are easily fooled. It may be exaggerated through approximation, conditions of derivation, and extrapolating from some conditions (...) of decomposition illegtimately to others. Evolved systems particularly may require analyses under alternative complementary decompositions. Exploring these conditions helps us to better understand the strengths and limits of reductionistic methods. (shrink)

The use of multiple means of determination to “triangulate” on the existence and character of a common phenomenon, object, or result has had a long tradition in science but has seldom been a matter of primary focus. As with many traditions, it is traceable to Aristotle, who valued having multiple explanations of a phenomenon, and it may also be involved in his distinction between special objects of sense and common sensibles. It is implicit though not emphasized in the distinction between (...) primary and secondary qualities from Galileo onward. It is arguably one of several conceptions involved in Whewell’s method of the “consilience of inductions” (Laudan 1971) and is to be found in several places in Peirce. (From M. Brewer and B. Collins, eds., (1981); Scientific Inquiry in the Social Sciences (a festschrift for Donald T. Campbell), San Francisco: Jossey-Bass, pp. 123–162.). (shrink)

From at least the time of the writing of The Philosophical Fragments , Søren Kierkegaard's work takes a special interest in both the transition from unbelief to faith and the character of the life of true faith. Trained in Lutheran dogma and convinced of the radical nature of human freedom, his work on this subject demonstrates a profound concern for and grasp of Lutheran orthodoxy, as well as a remarkable degree of subtlety. After all, it is no simple task to (...) give an account of the central features of the Christian life that is faithful to both a libertarian conception of human freedom and the doctrines of the church founded by the author of The Bondage of the Will . This paper proposes to accomplish two things: first, to state a problem that lies on the surface of Kierkegaard's account of the transformation involved in Christian conversion and second to present a resolution of the problem that is faithful to Kierkegaard's intentions. (shrink)

Scientific models may be more useful for false assumptions they make than true ones when one is interested not in the fit of the model, but in the form of the residuals. Modeling Darwin’s “blending” theory of inheritance shows how it illuminates features of Mendelian theory. Insufficient understanding of it leads to incorrect moves in modeling population structure. But it may prove even more useful for organizing a theory of cultural evolution. Analysis of “blending” inheritance gives new tools for recognizing (...) population structure for culture and for understanding differences between biological and cultural inheritance. (shrink)

The reductionistic vision of evolutionary theory, "the gene's eye view of evolution" is the dominant view among evolutionary biologists today. On this view, the gene is the only unit with sufficient stability to act as a unit of selection, with individuals and groups being more ephemeral units of function, but not of selection. This view is argued to be incorrect, on several grounds. The empirical and theoretical bases for the existence of higher-level units of selection are explored, and alternative analyses (...) discussed critically. The success of a multi-level selection theory demands the recognition and development of a multi-level genetics. The way to accomplish this is suggested. The genotype/phenotype distinction also requires further analysis to see how it applies at higher levels of organization. This analysis provides a way of defining genotype and phenotype for cultural evolution, and a treatment of the innate-acquired distinction which are both generalizeable to analyze problems of the nature and focus of scientific change. (shrink)

This paper attempts to provide a conceptual underpinning for codes of ethics in business and the professions. Rule-utilitarianism is a theory of ethics which I believe can successfully do this. Business persons and professionals, hopefully, will be able to develop codes of ethics in a manner consistent with a well-formulated general ethical theory. This will help enable codes of ethics to be a bridge between general ethical theory and specific ethical decisions made in business and the professions.

Scientific models may be more useful for false assumptions they make than true ones when one is interested not in the fit of the model, but in the form of the residuals. Modeling Darwin’s “blending” theory of inheritance shows how it illuminates features of Mendelian theory. Insufficient understanding of it leads to incorrect moves in modeling population structure. But it may prove even more useful for organizing a theory of cultural evolution. Analysis of “blending” inheritance gives new tools for recognizing (...) population structure for culture and for understanding differences between biological and cultural inheritance. (shrink)

After an initial discussion of the character of interdisciplinary linkages between complex disciplines, I consider an area with confluences of many diverse disciplines—the study of cultural evolution. This must embrace not only the traditional biological sciences, but also the multiple often warring disciplines of the human sciences. This interdisciplinary articulation is in its early stages compared, e.g., to that of evolutionary biology or evolutionary developmental biology, and I try to lay out major axes along which its articulation should plausibly occur, (...) given the relevant causal processes acting at different levels. One cannot have an adequate account of cultural evolution without recognizing a central role for cognitive and social development and the social and cultural organizations and institutions and artifactual tools and infrastructure that support and structure these developmental processes. These induce a population structure that mediates the transmission, expression, and elaboration of culture, and in particular the different ways in which they scaffold learning and the development and articulation of complex skills. I consider how these elements should articulate the disciplines that tend to focus separately on them. Intentions and the market are not explicitly included in this account, and I consider ways in which these perspectives might enter. (shrink)

Mesoudi et al.'s new synthesis for cultural evolution closely parallels the evolutionary synthesis of Neo-Darwinism. It too draws inspiration from population genetics, recruits other fields, and, unfortunately, also ignores development. Enculturation involves many serially acquired skills and dependencies that allow us to build a rich cumulative culture. The newer synthesis, evolutionary developmental biology, provides a key tool, generative entrenchment, to analyze them. (Published Online November 9 2006).

Michael Weisberg has given us a lovely book on models. It has very broad coverage of issues intersecting the nature of models and their use, an extensive consideration of long ignored “concrete” models with a rich case study, a discussion and classification of the many diverse kinds of models, and a particularly groundbreaking and innovative discussion of similarity concerning how models relate to the world. Included are insightful discussions of increasingly used “agent based” models, and the conjoint use of multiple (...) models in looking for robust results. Weisberg fills in some discussions with modeling and simulation results of his own.In addition, he considers and critiques other recent competing views on models, including the increasingly popular “models as fictions” account. His discussion is clear and technically precise without being needlessly so, and his distinctions are useful. The scientist is more likely to recognize his objects than the semantic theorist, and that is how it .. (shrink)