Current COVID-19 pandemic and previous SARS/MERS outbreaks have caused a series of major crises to global public health. We must integrate the large and exponentially growing amount of heterogeneous coronavirus data to better understand coronaviruses and associated disease mechanisms, in the interest of developing effective and safe vaccines and drugs. Ontologies have emerged to play an important role in standard knowledge and data representation, integration, sharing, and analysis. We have initiated the development of the community-based Coronavirus Infectious Disease Ontology (CIDO). (...) As an Open Biomedical Ontology (OBO) library ontology, CIDO is an open source and interoperable with other existing OBO ontologies. In this article, the general architecture and the design patterns of the CIDO are introduced, CIDO representation of coronaviruses, phenotypes, anti-coronavirus drugs and medical devices (e.g. ventilators) are illustrated, and an application of CIDO implemented to identify repurposable drug candidates for effective and safe COVID-19 treatment is presented. (shrink)
Unethical behavior is under-examined in the workplace. To date, few studies have attempted to explore the antecedents of an employee’s ethical decisions, particularly with respect to unethical behavior and its effects. To capture an employee’s psychological perception of unethical behavior in the workplace, this paper integrates organizational factors into the Theory of Reasoned Action. By conducting an empirical study in a Chinese firm, we found that codes of conduct and performance pressure have a significant influence on an employee’s attitude toward (...) and social beliefs about unethical behavior. We also demonstrated that employees’ unethical behaviors affect the firm performance of an entrepreneurial venture. The insights gleaned from the findings on this Chinese company have a number of important implications for both research and practice. (shrink)
Social networking sites have challenged ethical issues about users’ information security and privacy. SNS users are concerned about their privacy and need to control the information they share and its use. This paper examines the security of SNS by taking a look at the influence of users’ perceived control of information over their information-sharing behaviors. Employing an empirical study, this paper demonstrates the importance of perceived control in SNS users’ information-sharing behaviors. Specifically, perceived control has been found to be negatively (...) related to perceived privacy risk and attitude toward information sharing, which in turn has an impact on their information-sharing behaviors. In addition, gender has been shown to be an important factor that moderates the influences of both perceived control and perceived privacy risk on SNS users’ attitudes toward information sharing. Theoretical and practical implications are discussed. (shrink)
The content of existence theorems in the calculus of variations has been explored and an effective treatment of semi-continuity has been achieved. An algorithm has been developed which captures the natural algorithmic content of the notion of a semi-continuous function and this is used to obtain an effective version of the “chattering lemma” of control theory and ordinary differential equations. This lemma reveals the main computational content of the theory of relaxed optimal control.
This paper is to argue that conductive arguments could be understood from a rhetorical perspective. It contends that conductive arguments can be regarded as a particular mode of strategic maneuvering, rather than a new type of argument. Moreover, it demonstrates that the use of conductive arguments can be adequately analyzed and evaluated by adopting the theoretical tools developed in the extended Pragma-Dialectics.
China has a longstanding tradition of stressing the values of harmony and coherence, and Chinese society has often been portrayed as a culture in which conflict avoidance is viewed more positively than direct confrontation and argumentation. In order to evaluate the validity of this claim, this paper sketches Chinese people’s feelings and understandings about interpersonal arguing by reporting results of a data collection in China, using measures of argumentativeness, verbal aggressiveness, argument frames, and personalization of conflict. These results were compared (...) to those from a US sample. Chinese and US data differed in complex ways, but did not show Chinese respondents to be more avoidant. The Chinese correlations among variables were a reasonable match to expectations based on Western argumentation theories, although they did not replicate the US results precisely. The paper offers evidence that Chinese respondents had a more sophisticated understanding of interpersonal arguing than their US counterparts, and were more sensitive to the constructive possibilities of face-to-face disagreement. (shrink)
Argument by analogy has long been regarded as the characteristic way of arguing in ancient Chinese culture. Classic Chinese philosophers not only prefer to use analogy to argue for their own views, but also take efforts to theorize it in a systematic way. This paper aims to provide a careful study on the relevant ideas in ancient China in order to reconstruct the ancient Chinese theory of argument by analogy, and then to reveal some of its distinctive features through a (...) comparison with the Western counterpart account as developed by Aristotle. It is indicated that in ancient China analogical argument was conceived primarily as a way of arguing based on classification, with a unique mechanism of taking and giving according to kind. On that basis, it is argued that although such a characterization captures the logical structure of analogical argument in a similar way to Aristotle, the ancient Chinese theory stresses the foundational role of a particular notion of kind, thus makes the construction and application of analogical arguments become highly flexible and context-sensitive. Moreover, it is also contended that in ancient China the rationale of analogical arguments is explained from a general perspective of kind, relying upon the universal knowledge pertaining to the forming of kinds. Then it is further revealed that, unlike Aristotle who emphasizes the causal links between attributes in the physical world, ancient Chinese thinkers justify analogical argument by appealing to some normative metaphysical and epistemological principles. (shrink)
Corruption as a non-market strategy for firms has gained increasing attention in the field of strategy management. However, the effect of corruption on innovation is unclear, especially in the context of transition economies. Using institutional theory, we examine the relationship between corruption and new product innovation and identify the contextual conditions of the relationship. Using the World Bank Enterprise Survey data from China, our empirical results show that corruption has a positive effect on firms’ new product innovation. Moreover, we find (...) that policy instability and competitive threats from the informal sector positively moderate the relationship between corruption and new product innovation. Using post hoc analysis, we find that the potentially positive effect of corruption on new product innovation is the consequence of inherent institutional weaknesses in transition economies; as the level of institutional development increases, the effect of corruption on firms’ new product innovation will gradually decrease. Overall, our findings provide new insights into understanding corrupt behaviors in transition economies and present managerial implications for firms’ ethical dilemmas in a transition economy context. We argue that the key to overcoming these ethical dilemmas lies in promoting pro-market institutional reform to reduce the potential benefits of corruption. (shrink)
Soft-sensor technology plays a vital role in tracking and monitoring the key production indicators of the grinding and classifying process. Least squares support vector machine, as a soft-sensor model with strong generalization ability, can be used to predict key production indicators in complex grinding processes. The traditional crossvalidation method cannot obtain the ideal structure parameters of LSSVM. In order to improve the prediction accuracy of LSSVM, a golden sine Harris Hawk optimization algorithm was proposed to optimize the structure parameters of (...) LSSVM models with linear kernel, sigmoid kernel, polynomial kernel, and radial basis kernel, and the influences of GSHHO algorithm on the prediction accuracy under these LSSVM models were studied. In order to deal with the problem that the prediction accuracy of the model decreases due to changes of industrial status, this paper adopts moving window strategy to adaptively revise the LSSVM, which greatly improves the prediction accuracy of the LSSVM. The prediction accuracy of the regularized extreme learning machine with MW strategy is higher than that of MW-LSSVM at some moments. Based on the training errors of LSSVM and RELM within the window, this paper proposes an adaptive hybrid soft-sensing model that switches between LSSVM and RELM. Compared with the previous MW-LSSVM, MW-neural network trained with extended Kalman filter, and MW-RELM, the prediction accuracy of the hybrid model is further improved. Simulation results show that the proposed hybrid adaptive soft-sensor model has good generalization ability and prediction accuracy. (shrink)
There are generally two controversial issues over Kant's solution to the free will problem. One is over whether he is a compatibilist or an incompatibilist and the other is over whether his solution is a success. In this paper, I will argue, regarding the first controversy, that “compatibilist” and “incompatibilist” are not the right terms to describe Kant for his unique views on freedom and determinism; but that of the two, incompatibilist is the more accurate description. Regarding the second controversy, (...) I will argue that Kant's solution to the free will problem is not a success because his effort in making the effects of freedom part of the field of appearance has made his solution incoherent and ambiguous. Despite this, I argue that Kant's attempt to solve the free will problem is groundbreaking because he at least has separated freedom from the dominance of determinism. (shrink)
Recent theoretical advances describing consciousness from information and integration have highlighted the unique role of the thalamocortical system in leading to integrated information and thus, consciousness. Here, we examined the differential distributions of specific and nonspecific thalamocortical functional connections using resting-state fMRI in a group of healthy subjects and vegetative-state patients. We found that both thalamic systems were widely distributed, but they exhibited different patterns. Nonspecific connections were preferentially associated with brain regions involved in higher-order cognitive processing, self-awareness and introspective (...) mentalizing . In contrast, specific connections were prevalent in the ventral and posterior part of the prefrontal and precuneus, known involved in representing externally-directed attentions. Significant reductions of functional connectivity in both systems, especially the nonspecific system, were observed in VS. These data suggest that brain networks sustaining information and integration may be differentiated by the nature of their thalamic functional connectivity. (shrink)
Based on its productionguideline, organic agriculture has set foritself the goals of minimizing all forms ofpollution and maintaining sustainability of thefarming system. By striving for these goals,organic farming meets the demands of anincreasing number of consumers who are criticalof conventional production methods. This papergives an overview of the present state of theart in the different issues. Possibilities ofand limitations in performing the self-aimedgoals under the basic standards of organicagriculture are discussed. Concerningenvironmental protection, in general, the riskof adverse environmental effects is (...) lower withorganic than with conventional farming methods,though not necessarily so; with reference tosoil fertility and nutrient management, organicfarming is suited to improve soil fertility andnutrient management markedly on the farm level;regarding biodiversity, comparison studies showthat organic farming has more positive effectson biodiversity conservation; in relation toproduct quality, under the basic standards oforganic farming, there is no sufficientevidence for a system-related effect on productquality due to the production method. (shrink)
In this paper, the properties of the super quantum measures are studied. Firstly, the products of Dirac measures are discussed; Secondly, based on the properties of Dirac measures, the structures of super quantum measures are characterized; At last, we prove that any super quantum measure can determine a unique diagonally positive strongly symmetric signed measure. This result verifies the conjecture which was proposed by Gudder.
In a recent paper, “One Logician’s Perspective on Argumentation”, van Benthem expressed his reservations on Toulmin’s diagnosis and abandonment of formal logic, and argued that Toulmin was wrong for leading the study of argumentation apart from formal approach. In this paper we will try to reveal two se-rious misunderstandings of Toulmin’s ideas in his discussions, and thereby make an apology for Toulmin.
There were two prevailing sentiments in Europe after the Reformation: One opposing papal authority and one advocating individual freedom. This paper analyzes these two sentiments and finds that the concept of conscience is crucial in understanding them. The issue of conscience is about judging truth and good, and in initiating the Reformation, Martin Luther heavily appealed to his conscience while countering Catholic attacks. With the wide dispersal of the Reformation, Luther’s notion of conscience was well received among his supporters throughout (...) Europe. Descartes later transformed Luther’s conscience into an epistemological being (the cogito ), and argued that its existence was the only valid thing that survived his thorough skepticism — and as such is the foundation of human knowledge. Rousseau continued this line of thinking, which we call subjectivism, and re-employed the term conscience as a replacement for cogito , holding that conscience is the final authority in judging good and bad; that, as the starting point of human existence, it cannot be withheld from any human being; and that it therefore constitutes an inalienable human right. This paper argues that the Enlightenment was a subjectivist movement propelled by this conscience- cogito -conscience conceptualization, and that it sought to enlighten this inalienable conscience. (shrink)