The hematopoietic system consists of more than ten differentiated cell types, all of which are derived from a single type of hematopoietic stem cell. The accessibility and interest of this system have made it a model for understanding normal and abnormal differentiation of mammalian cells. Newer techniques have generated a mass of data that requires integrative approaches for analysis and interpretation. The traditional view of the differentiation program holds that a small number of regulators are involved in each stage of (...) cell specification. However, this may not be the case. Recent analyses have shown that almost all substantial subsets of genes, including the set of broadly expressed transcription factors, are expressed in patterns that are unique for each lineage. Further, much of this difference between lineages can be captured in two‐dimensional graphs. Understanding the biologic significance, mechanisms and constraints underlying these differences is a challenge for experimentalists and computational biologists alike. BioEssays 26:1276–1287, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

張載思想在當代儒學界引發熱烈論辯， 他是「理學宗師」？還是「氣學之祖」？ 是「唯物論／唯氣論」者？ 還是「即存有即活動」的儒家「心性論」、「道德的形上學」？ 針鋒相對的各種詮釋，使得張載格外具有研究趣味， 也展現他在當代儒學上的學術潛力。 《當代張載學》對張載的關懷集中在心性論與氣化論的交涉之上。作為北宋理學宗師，如同牟宗三以「天道性命相貫通」為張載的中心課題，唐君毅以「人道合天道之道」標示橫渠學性格，天、道、性、心的確是張載經常使用的 核心語詞，張載學乃是儒家傳統意義下的心性論與道德形上學。然而在心性論之外，張載同時使用大量的氣論語言，並且經常在氣化流行中説明世界誠明、物與無妄。由此形成的大有哲學，正是對抗佛老的利器。切割大量氣論， 無疑違反《正蒙》初心。「太虛即氣」正是張載刻意把氣帶入天道性命論域的新哲學命題。 可惜的是，理學內部高舉〈西銘〉，貶抑《正蒙》，「以氣說道」成為對張載經常使用的批評。相較於張載在理學史上未被善待的命運，一九四九年後唯物論氣學與新儒家心性論，或晚近新儒家心性論與先天型氣學的論辯，張載 卻是一重要戰場。當中牽涉對氣的理解，也摻雜政治對立因素，並涉及儒學典範的挑戰。一個張載，多種面貌，其間的拮抗張力使當代張載研究更有挑戰性。張載強調兩端一致、兼體無累，本書相信不僅唯心、唯物對立框架不適 用於張載，也認為心性論與氣化論不必然是二擇一的選題。張載具有打破二元框架、平視心物的潛力，此有待於重新檢證其氣學性格。.

內容簡介 儒學不應僅是「思辯哲學」或「實踐理論」。從「半日靜坐，半日讀書」到當代身體觀，透過理學工夫論研究，反思儒學進入現代西方學術之轉譯過程，所產生的實踐脫落，召喚逐漸被學院哲學遺忘的實踐向度。 本書是一部探討宋明理學工夫論的著作，雖概括不同時代理學家，但貫穿其間的是儒學作為「實踐之學」的基本信念。儒學現代化過程中，在學科分類下被勉強劃入「哲學」學門，但哲學家一向擅長以理論的方式探討實踐，卻往 往無法自己親自實踐。當代儒學也出現一個難題：學術化的儒家哲學如何「實踐」？如何不僅成為「思辯哲學」或「實踐理論」？如何避免「實踐的脫落」？此實是儒學現代化、學術化下的一項挑戰。 藉著回顧理學傳統的修養方法，尋找返本開新的可能。本書關注理學工夫的具體實踐與操作方法，如何被運作、展開；此訴求下，靜坐、讀書與與身體觀，是本書比較集中探討的理學工夫論面向。將工夫論研究，由思想文獻中靜 態結構描述的「實踐理論」，返回實修實證的動態歷程之展現。使儒家哲學研究從心性形上學，往身體向度落實，發展成完整的「身心之學」。 名人推薦 理學做為成德之學，向來與生命實踐密不可分。實踐工夫成為理學家日常性功課，甚至以證本體為生命大事，那種古典求道精神的實踐神聖性，在當今學術專技化的客觀年代，已逐漸成為一種實踐理論之客觀研究。而當存在體驗 化為抽象理論時，理學原初最濃厚的實踐動能與召喚力道，是否也將靈光消逝？本書作者的初發心，便具有這種存在的憂心與感受。換言之，身為現代的學者，作者仍懷有強烈的求道之古典關懷。本書的基本主題關涉：靜坐與讀 書這兩種工夫論的辯證，而除了心性修養的傳統論述以外，作者亦吸收當代的身體實踐觀點，企圖更為完整地描述理學家身心一體轉化的體證內涵。現今從事理學工夫理論的研究者不算少，但在理論與實踐之間尋尋覓覓者已不多 ，在這種儒門淡泊的工夫遺忘的現代氣氛下，作者的懷古初心尤為可貴，其研究成果也值得觀察。──賴錫三╱中山大學中文系教授 現代儒學研究，儒家的工夫論常被本體論取代，而呈失語現象。此書真正立基於工夫實踐的立場，可做為現今儒者內聖學道德實踐之重要參考著作。──廖俊裕╱南華大學生死學系副教授.

This book reinterprets classical Chinese philosophical tradition along the conceptual line of human dignity. Through extensive textual evidence, it illustrates that classical Confucianism, Mohism and Daoism contained rich notions of dignity, which laid the foundation for human rights and political liberty in China, even though, historically, liberal democracy failed to grow out of the authoritarian soil in China. The book critically examines the causes that might have prevented the classical schools from developing a liberal tradition, while affirming their positive contributions (...) to the human dignity concept. Analysing the inadequacies of the western concept of human dignity, the text covers relevant teachings of Kongzi, Mengzi, Xunzi, Mozi, Laozi and Zhuangzi (in comparison with Rousseau). While the Confucian notions of humanity (Ren), righteousness (Yi), and gentleman (Junzi) bear most directly on the conception of dignity, Mohism and Daoism provide salutary corrections to the ossification of the orthodox Confucian practice (Li). (shrink)

Tianyi Zhang offers in this study an innovative philosophical reconstruction of Shihāb al-Dīn al-Suhrawardī's (d. 1191) Illuminationism. Commonly portrayed as either a theosophist or an Avicennian in disguise, Suhrawardīappears here as an original and hardheaded philosopher who adopts mysticism only as a tool of philosophical inquiry. Zhang makes use of Plato's cave allegory to explain Suhrawardī's Illuminationist project. Focusing on three areas-the theory of presential knowledge, the ontological discussion of mental considerations, and Light Metaphysics-Zhang convincingly reveals the (...) Nominalist and Existential nature of Illuminationism, and thereby proposes a new way of understanding how Suhrawardī's central philosophical ideas cohere. (shrink)

Truth pluralism is the view that there is more than one truth property. The strong version of it (i.e. strong pluralism) further contends that no truth property is shared by all true propositions. In this paper, I help strong pluralism solve two pressing problems concerning mixed discourse: the problem of mixed inferences (PI) and the problem of mixed compounds (PC). According to PI, strong pluralism is incompatible with the truth- preservation notion of validity; according to PC, strong pluralists cannot find (...) any appropriate truth property for mixed compound propositions, whose atomic constituents are from different domains of discourse (e.g., <sky is blue and chocolate is tasty>). I argue that the strong pluralist is motivated to take the truth predicate in truth-involving universal statements to be deflationary to avoid the two pressing problems. Such a move entails that the truth predicate in the platitude of validity (V) for any argument, it is valid if and only if necessarily its conclusion is true when its premises are all true does not denote any substantive truth property. Instead, it is merely an expressive device to help people generalize instances of (V) to (V). Analogous stories hold for the truth predicate in the platitudes of compound (e.g., conjunction). The upshot is that, the strong pluralist can solve PI and PC by further conceding that mixed compounds are true/false in a deflationary way. (shrink)

中国儒学缄默维度是在语言关闭的缄默中，转向静的深度体证，具有渊与根两个特征，集约表达为“藏心于渊，美厥灵根”，诗意表达为“氤氲一气似初春”。本书从孔子观周见金人“三缄其口”开始，以方以智证成太极丸春结 束，选取颜回、言偃、扬雄、周敦颐、朱熹、杨简、文天祥、王阳明及其后学胡直与万廷言、刘宗周、王夫之等重要儒者，溯源至孟子、《易传》、庄子、屈原四个先秦流派的展开与互动，围绕罕言与雅言、深静与真动、冲然与 恬愉、主静与持敬、艺术大美与道德至善等重点问题，挖掘中国儒学缄默维度的深蕴及特质，并展望其在现代语境的展开，重写中国儒学史。.

In his paper, “A Causal Argument for Physicalism” (Zhong, 2023), Zhong presents a novel argument for non-reductive physicalism (which he calls “A2”), based on the causal argument for reductive physicalism (which he calls “A1”), and claims that A2 is better than A1 since the premises in A2 are more plausible than those in A1. In this paper, I will argue that A2 fails to be a sound argument for non-reductive physicalism, or even physicalism per se, because the premises in A2 (...) can be fulfilled by the kind of dualism which claims that the physical event (P), the mental event (M), and their effect (E) form a causal chain and that P and M are simultaneous causes. Also, I will argue that we do have ways to strengthen A2 to block the aforementioned problem. But the only plausible way to strengthen the argument is to appeal to the conservation of energy and momentum. And this favors A1 more than A2. So, I conclude that A2 is not better than A1, and a causal argument for physicalism still naturally favors reductive physicalism. (shrink)

To understand the qualities of Western civilization and its modernity, to think about the future of humanity, and to understand how modern science was gestated in Western civilization: in the author’s view, these are the most important reasons to do history of science research in China. Study of the history of Western science in China is in its infancy, and there are great deficiencies leading to its lagging behind the international world of scholarship. In this situation, the most urgent task (...) is to translate as soon as possible a batch of high quality and classic books in the field, to establish a basic academic platform for research in the history of science, and, once that foundation has been laid, to deepen our researches further. Given these considerations, this essay discusses why the author translates works on the history of science, how he chooses books for translation, and his experiences as a translator. (shrink)

C.S. Peirce offered an evaluation of Bentham's philosophy to the effect that on some points Bentham's performance was of great value, but essentially, he was ‘a shallow logician’ confined to analysis of ‘lower motive’. This paper argues that Bentham's logic is deeply metaphysically based, multi‐levelled, and comprehensive. There are at least three constituent parts in his utilitarian logic: the first is his ontology, with its distinction between real and fictitious entities, and with pain and pleasure constituting the core real entities; (...) the second is his reductionism in, and analytical view of, simple and complex pleasures and pains; the third is the distinction between private ethics and public ethics. Bentham's logic is staunchly based on empiricism and truth and he developed a pragmatic utilitarian solution to overcome the potential impasse of Hume's scepticism through a mechanism of reflection. Even the doctrines of belief and abduction embraced and developed by Peirce are contained in Bentham's utilitarian logic. Bentham would certainly take Peirce's philosophy as ipse dixitism. Peirce was not in fact a serious reader of Bentham and failed to employ the distinction between argument and argumentation in his study of Bentham's logic. (shrink)

Early and later Confucians, known in Chinese as the “ruists” school of ancient origins, perceived the idea of “harmony” as a fundamental concept that lies at the basis of self-cultivation, society and governance. In modern times this idea still plays in one or another form a dominant note in Chinese politics and social life. The article attempts to search for causes of the significance of “harmony” by focusing on analyzing two pivotal Confucian texts compiled in the Han dynasty, namely, Records (...) of Music [Yue ji 樂記] and Divination of Music [Yue wei 樂緯]. The analysis shows that ruists belonging to Zhou dynasty’s imperial class of music officials, gradually developed the aesthetics of music into a complex idea of "harmony" that contains the highest aesthetical way—“Dao”—which guides both the whole universe as well as the evolution of human society. (shrink)

本书收录了张家龙先生有关西方逻辑史论,数理逻辑史论以及中国逻辑史论的相关文章,是作者多年研究的精华集.他用现代逻辑的技术重新构建了亚里士多德的直言三段论和模态三段论系统,用现代逻辑观点对亚里士多德的模 态命题逻辑,关系理论和偏好理论作了解释,将欧洲中世纪逻辑的成果构建成类似模态逻辑S3的系统.全面系统地研究了从莱布尼茨到哥德尔的数理逻辑发展史.他在中国逻辑史研究方面,从数理逻辑观点构造了"周易"的形 式公理系统,用现代逻辑方法将'侔'式推理概括为两类共6种有效式.他研究了艾耶尔,布拉德雷和罗素的哲学思想,提出一些新见解.在逻辑哲学研究方面,他分析了国内外已有的悖论定义,提出了不同定义;提出了关于可 能世界的'模态结构论';对本质主义的观点作了新的辩护.

本书以人物、机构和刊物为抓手，对16-18世纪儒学西传欧洲进行了全面的梳理和总结，对中国古代文化经典外译的数量和时段做了初步的划分，也对我国中学西传研究滞后的原因做了分析。.

Rubin loves the beautiful sounds that are played by the orchestra. He wants to learn to play the violin and make his own music. But when Rubin plays, it doesn't sound like he imagines it should. Rubin goes into the forest to practice alone and despite only getting the violin to screech, he finds an unlikely audience that loves his unique style.

本书以向历史借鉴智慧为出发点，以人为本，从探寻人类生活基本问题出发，解读中国国学的优良传统及核心价值。在中国人五千年的历程中爬梳剔抉，把国学的精华复活在当代人的面前，蕴含着中华文明的博大精深，也浸透着 一代国学大师的睿智灼见，是中国经典国学智慧与当今精神生活所需的融会贯通。.