Physical contact between organelles are widespread, in part to facilitate the shuttling of protein and lipid cargoes for cellular homeostasis. How do protein‐protein and protein‐lipid interactions shape organelle subdomains that constitute contact sites? The endoplasmic reticulum (ER) forms extensive contacts with multiple organelles, including lipid droplets (LDs) that are central to cellular fat storage and mobilization. Here, we focus on ER‐LD contacts that are highlighted by the conserved protein seipin, which promotes LD biogenesis and expansion. Seipin is enriched in ER (...) tubules that form cage‐like structures around a subset of LDs. Such enrichment is strongly dependent on polyunsaturated and cyclopropane fatty acids. Based on these findings, we speculate on molecular events that lead to the formation of seipin‐positive peri‐LD cages in which protein movement is restricted. We hypothesize that asymmetric distribution of specific phospholipids distinguishes cage membrane tubules from the bulk ER. (shrink)

本書意在對中國哲學史史料學的學科演變歷程進行系統梳理，將中國哲學史史料學史分為萌芽、形成、發展和突破四個歷史時期，並在萌芽階段以胡適和梁啟超為代表，在形成階段以朱謙之和馮友蘭為代表，在發展階段以張岱年 、劉建國和石峻為代表，在突破階段以蕭萐父、劉文英和商聚德、韓進軍為代表逐步展現中國哲學史史料學學科各個時期的面貌特徵。在此基礎上，本書總結了中國哲學史史料學的學科發展規律，並預測了其未來走勢。.

作者自接觸老子後，從暸解與省思《道德經》中，感到其歸於天地自在的言詞，可使人身心歸於平靜，因而感受到《道德經》是適合人與天地萬物的哲學。 以天地自然運行的法則與人回歸自然良善本質「孝慈」為出發，向天學習效法，從整體正向以善的光輝，從人的自然良善本質「孝慈」，與國家執政者的影響與責任，以達人與萬物的恆久遠的發展。.

本书以20世纪全球社会经济、政治、精神体系的世界震荡为背景,剖析思维革命家们创立的五项思维方法论,及马克思主义戏剧化的兴衰变化历程。.

本书侧重分析中华民族哲学智慧的个性及其对人类哲学文明发展的特殊贡献。中华文明从未间断并发展下来的哲学原因是中华民族不断开发不断完善的直观智慧,中华民族的哲学精神为人类简单明了地指出了走出民族冲突与宗教 冲突困惑的思路。.

Chu tu wen xian yu ru dao guan xi " nei rong jian jie: ru dao guan xi shi yi xiang gui mo hong da de yan jiu ke ti, ta she ji daozheng ge Zhongguo si xiang shi de nei zai jie gou he fa zhan guo cheng, she ji dao Zhongguo wen hua jin hou de zou xiang, yi yi zhong da. Er shi shi ji yi hou, yi huo de le shu liang ke guan de yan jiu (...) cheng guo. Zui jin chu tu wen xian de da liang yong xian you wei zhe ge wen ti de tao lun ti gong le xu duo xin cai liao, xin shi ye, xin guian dian."Chu tu wen xian yu ru dao guan xi " shou ji le 30 duo pian you dai biao xing de lun wen, tong guo "Kong Lao Meng Zhuang zhi bian", "Ru dao hu bu yu ying xiang", "Chu tu wen xian xin shi ye" san ge ban kuai jia yi cheng xian, xi wang du zhe jie ci dui yi wang ru dao guan xi yan jiu de fa zhan mai luo yu kuang jia you zong ti de ba wo, bing you ci kai chu xin de yan jiu tian di. (shrink)

From reviews of the hardback edition: a deep study of 20th century field ... of the conceptual origins and development of twentieth century field theories, ...

Introduction: On the Huang-Lao tradition of Daoist thought. Looking at the basic characteristics of Huang-Lao Daoism -- Reviewing past research and looking to the future -- How does the idea of a "Huang-Lao Daoist" school stand up to scrutiny? -- A brief introduction to the contents of this book -- Conclusions -- Huang-Lao Daoism research in light of excavated texts. Introduction -- Two types of theories regarding Dao and governance in the Huangdi Sijing -- Early Huang-Lao thought in bamboo manuscripts (...) from the ancient state of Chu -- Conclusions -- Huang-Lao thought and folk techniques and calculations: using clues from excavated texts. A look back at previous studies -- Techniques and calculations in textual images of the Yellow Emperor -- The relationships between the concepts of "forms and names" and "forms/punishment and virtue/bounty" and techniques and calculations -- Linguistic characteristics of techniques and calculations in Huang-Lao texts -- Conclusion -- The literary structure and characteristics of the thought in the bamboo manuscript known as All Things Flow into Forms (Fanwu Liuxing). Introduction -- The literary structure of the Fanwu Liuxing -- The characteristics of thought in the Fanwu Liuxing -- Some last observations -- From auto-creation to autonomy: an analysis of political philosophy in the Hengxian. Introduction -- Past research -- Self-generation from Pre-Qin, throughout Qin to the Han dynasties -- The parallel between the sections of the Hengxian -- Concluding remarks -- The idea of names or naming as one of the key concepts in the Huangdi Sijing: discussing the relationship between the concepts of the schools of Dao, names and legality. Preface -- The kinds of names seen in the Huangdi Sijing -- Surveying names in the Huangdi Sijing -- The relationship between ruler and names -- The relationship between names and law -- Conclusion. (shrink)

全书共分回顾与展望、继承与创新、征程与轨迹三部分。主要内容包括:一次难度的申报国家项目的经历;三十年间两三事;难以忘却的记忆;且放白鹿青崖间;入会二十年琐忆;相干条件句命题逻辑系统BW等。.

限制級小說，未成年請勿閱聽 身心俱虐的BL情深 ＹＹ耽美小說的極端， 「攻」與「受」間不可說的一片空白.

Auditory perception is traditionally conceived as the perception of sounds — a friend’s voice, a clap of thunder, a minor chord. However, daily life also seems to present us with experiences characterized by the absence of sound — a moment of silence, a gap between thunderclaps, the hush after a musical performance. In these cases, do we positively hear silence? Or do we just fail to hear, and merely judge or infer that it is silent? This longstanding question remains controversial (...) in both the philosophy and science of perception, with prominent theories holding that sounds are the only objects of auditory experience and thus that our encounter with silence is cognitive, not perceptual. However, this debate has largely remained theoretical, without a key empirical test. Here, we introduce a novel empirical approach, presenting experimental evidence that silence can be genuinely perceived (not just cognitively inferred). We ask whether silences can ‘substitute’ for sounds in event-based auditory illusions — empirical signatures of auditory event representation in which auditory events distort perceived duration. Seven experiments introduce three new ‘silence illusions’ — the one-silence-is-more illusion, silence-based warping, and the oddball-silence illusion — each adapted from a prominent perceptual illusion previously thought to arise only from sounds. Subjects were immersed in ambient noise interrupted by silences structurally identical to the sounds in the original illusions. In all cases, silences elicited temporal distortions perfectly analogous to the illusions produced by sounds. Our results suggest that silence is truly heard, not merely inferred, introducing a general approach for studying absence perception. (shrink)

On Nguyễn An Ninh political and social views.

中共浙江省委党校学科建设成果资助出版项目 “浙江省科学发展观与浙江发展研究中心”研究成果.

禮是華夏傳統文化的核心。先秦古禮幽眇，傳統禮儀研究聚訟紛紜，本書綜合利用甲骨、金文、簡帛等出土資料，對先秦時期的祼禮、朝聘禮、贈饋、牲體禮等禮儀做了多角度、多視野的綜合研究，對禮儀所蘊含的思想觀念提出 了獨到的認識。研究古禮的意義，不是要恢復古制或以古律今，而是為了探究其化民成德、敦睦群倫的功能，探求其內在的人文精神，以期稽古振今。.