Results for 'command cell behavior'

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  1.  21
    The Command Neuron Concept.Irving Kupfermann & Klaudiusz R. Weiss - 1978 - Behavioral and Brain Sciences 1 (1):3-10.
  2.  10
    Is “Wolf‐Pack” Predation by Antimicrobial Bacteria Cooperative? Cell Behaviour and Predatory Mechanisms Indicate Profound Selfishness, Even When Working Alongside Kin.Rupert C. Marshall & David E. Whitworth - 2019 - Bioessays 41 (4):1800247.
    For decades, myxobacteria have been spotlighted as exemplars of social “wolf‐pack” predation, communally secreting antimicrobial substances into the shared public milieu. This behavior has been described as cooperative, becoming more efficient if performed by more cells. However, laboratory evidence for cooperativity is limited and of little relevance to predation in a natural setting. In contrast, there is accumulating evidence for predatory mechanisms promoting “selfish” behavior during predation, which together with conflicting definitions of cooperativity, casts doubt on whether microbial (...)
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  3.  39
    Unintended Changes in Cognition, Mood, and Behavior Arising From Cell-Based Interventions for Neurological Conditions: Ethical Challenges.P. S. Duggan, A. W. Siegel, D. M. Blass, H. Bok, J. T. Coyle, R. Faden, J. Finkel, J. D. Gearhart, H. T. Greely, A. Hillis, A. Hoke, R. Johnson, M. Johnston, J. Kahn, D. Kerr & P. King - 2009 - American Journal of Bioethics 9 (5):31-36.
    The prospect of using cell-based interventions to treat neurological conditions raises several important ethical and policy questions. In this target article, we focus on issues related to the unique constellation of traits that characterize CBIs targeted at the central nervous system. In particular, there is at least a theoretical prospect that these cells will alter the recipients' cognition, mood, and behavior—brain functions that are central to our concept of the self. The potential for such changes, although perhaps remote, (...)
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  4.  19
    Physiological Electrical Fields Modify Cell Behaviour.Colin D. McCaig & Min Zhao - 1997 - Bioessays 19 (9):819-826.
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  5.  14
    The Hitchhiker's Guide to Motility. Cell Movement and Cell Behaviour. By J. M. LACKIE. Allen & Unwin. 1986. Pp. 316 £30.00 Hardcover £11.95 Paperback. [REVIEW]Alastair F. Brown - 1987 - Bioessays 7 (4):185-186.
  6.  12
    Nitric Oxide and Metastatic Cell Behaviour.Emma L. Williams & Mustafa B. A. Djamgoz - 2005 - Bioessays 27 (12):1228-1238.
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  7.  1
    The Importance of Parametric Approaches in the Analysis of Cell Behavior.Neil R. Smalheiser - 1996 - Perspectives in Biology and Medicine 40 (1):60.
  8.  23
    Collective Behavior in Cancer Cell Populations.Thomas S. Deisboeck & Iain D. Couzin - 2009 - Bioessays 31 (2):190-197.
  9.  5
    Is the Mauthner Cell a Kupfermann & Weiss Command Neuron?Robert C. Eaton, Chris M. Wieland & Randolf DiDomenico - 1986 - Behavioral and Brain Sciences 9 (4):725-727.
  10.  19
    The Concept of “Command Neurons” in Explanations of Behavior.C. A. Fowler & M. T. Turvey - 1978 - Behavioral and Brain Sciences 1 (1):20-22.
  11.  20
    Central Command and Reflex Regulation: Cardiovascular Patterns During Behavior.Alberto Del Bo & Alberto Zanchetti - 1986 - Behavioral and Brain Sciences 9 (2):297-298.
  12.  18
    Animal-Human Chimeras, Sexually Deviant Behavior, and Embryonic Stem Cell Research: An Introduction.A. E. Hinkley - 2009 - Journal of Medicine and Philosophy 34 (5):439-446.
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  13.  7
    The Organismic Hypothesis and Differentiation of Behavior. I. The Cell Theory and the Neurone Doctrine.O. C. Irwin - 1932 - Psychological Review 39 (2):128-146.
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  14.  5
    Command Neurons and Unitary Behavior.John McCarthy - 1978 - Behavioral and Brain Sciences 1 (1):32-32.
  15.  4
    The Unpredictability of Cellular Behavior: Trivial or of Fundamental Importance to Cell Biology?M. B. Hallett - 1988 - Perspectives in Biology and Medicine 33 (1):110-119.
  16.  3
    Triggering and Organizing Functions of Command Neurons in Crayfish Escape Behavior.Jeffrey J. Wine - 1978 - Behavioral and Brain Sciences 1 (1):35-35.
  17.  15
    Excitable Behavior Can Explain the “Ping‐Pong” Mode of Communication Between Cells Using the Same Chemoattractant.Andrew B. Goryachev, Alexander Lichius, Graham D. Wright & Nick D. Read - 2012 - Bioessays 34 (4):259-266.
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  18. Is the Cell Really a Machine?Daniel J. Nicholson - 2019 - Journal of Theoretical Biology 477:108–126.
    It has become customary to conceptualize the living cell as an intricate piece of machinery, different to a man-made machine only in terms of its superior complexity. This familiar understanding grounds the conviction that a cell's organization can be explained reductionistically, as well as the idea that its molecular pathways can be construed as deterministic circuits. The machine conception of the cell owes a great deal of its success to the methods traditionally used in molecular biology. However, (...)
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  19.  35
    Developmental Motifs Reveal Complex Structure in Cell Lineages.Nicholas Geard, Seth Bullock, Rolf Lohaus, Ricardo B. R. Azevedo & Janet Wiles - 2011 - Complexity 16 (4):48-57.
    Many natural and technological systems are complex, with organizational structures that exhibit characteristic patterns but defy concise description. One effective approach to analyzing such systems is in terms of repeated topological motifs. Here, we extend the motif concept to characterize the dynamic behavior of complex systems by introducing developmental motifs, which capture patterns of system growth. As a proof of concept, we use developmental motifs to analyze the developmental cell lineage of the nematode Caenorhabditis elegans, revealing a new (...)
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  20.  8
    Asymmetric Segregation of Aged Spindle Pole Bodies During Cell Division: Mechanisms and Relevance Beyond Budding Yeast?Jette Lengefeld & Yves Barral - 2018 - Bioessays 40 (8):1800038.
    Asymmetric cell division generates cell diversity and contributes to cellular aging and rejuvenation. Here, we review the molecular mechanisms enabling budding yeast to recognize spindle pole bodies (SPB, centrosome equivalent) based on their age, and guide their non‐random mitotic segregation: SPB inheritance requires the distinction of old from new SPBs and is regulated by the SPB‐inheritance network (SPIN) and the mitotic exit network (MEN). The SPIN marks the pre‐existing SPB as old and the MEN recognizes these marks translating (...)
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  21.  32
    Cell Sociology: A Way of Reconsidering the Current Concepts of Morphogenesis.Rosine Chandebois - 1976 - Acta Biotheoretica 25 (2-3):71-102.
    Research in the field of planarian regeneration on the one hand, and a general survey of embryology on the other, throw doubt upon the reality of supra-cellular controls, which are still at the basis of all modern concepts of morphogenesis. The necessity of referring to such controls, which have never been convincingly demonstrated, is probably due to the fact that two aspects of cell behaviour have been underestimated: 1) the capacity of cells to change their individualities for a time (...)
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  22.  4
    Variation is Function: Are Single Cell Differences Functionally Important?Hannah Dueck, James Eberwine & Junhyong Kim - 2016 - Bioessays 38 (2):172-180.
    There is a growing appreciation of the extent of transcriptome variation across individual cells of the same cell type. While expression variation may be a byproduct of, for example, dynamic or homeostatic processes, here we consider whether single‐cell molecular variation per se might be crucial for population‐level function. Under this hypothesis, molecular variation indicates a diversity of hidden functional capacities within an ensemble of “identical” cells, and this functional diversity facilitates collective behavior that would be inaccessible to (...)
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  23. Muslim Perspectives on Stem Cell Research and Cloning.Fatima Agha Al-Hayani - 2008 - Zygon 43 (4):783-795.
    In Islam, the acquisition of knowledge is a form of worship. But human achievement must be exercised in conformity with God's will. Warnings against feelings of superiority often are coupled with the command to remain within the confines of God's laws and limits. Because of the fear of arrogance and disregard of the balance created by God, any new knowledge or discovery must be applied with careful consideration to maintaining balance in the creation. Knowledge must be applied to ascertain (...)
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  24.  28
    The Liberation of Life: From the Cell to the Community.Charles Birch - 1981 - Cambridge University Press.
    This book is about the liberation of the concept of life from the bondage fashioned by the interpreters of life ever since biology began, and about the liberation of the life of humans and non-humans alike from the bondage of social structures and behaviour, which now threatens the fullness of life's possibilities if not survival itself. It falls into a tradition of writings about human problems from a perspective informed by biology. It rejects the mechanistic model of life dominant in (...)
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  25.  16
    Parental Selection of Vocal Behavior.John L. Locke - 2006 - Human Nature 17 (2):155-168.
    Although all natural languages are spoken, there is no accepted account of the evolution of a skill prerequisite to language—control of the movements of speech. If selection applied at sexual maturity, individuals achieving some command of articulate vocal behavior in previous stages would have enjoyed unusual advantages in adulthood. I offer a parental selection hypothesis, according to which hominin parents apportioned care, in part, on the basis of their infants’ vocal behavior. Specifically, it is suggested that persistent (...)
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  26.  7
    Model and movement: studying cell movement in early morphogenesis, 1900 to the present.Janina Wellmann - 2018 - History and Philosophy of the Life Sciences 40 (3):59.
    Morphogenesis is one of the fundamental processes of developing life. Gastrulation, especially, marks a period of major translocations and bustling rearrangements of cells that give rise to the three germ layers. It was also one of the earliest fields in biology where cell movement and behaviour in living specimens were investigated. This article examines scientific attempts to understand gastrulation from the point of view of cells in motion. It argues that the study of morphogenesis in the twentieth century faced (...)
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  27.  5
    BCI-Mediated Behavior, Moral Luck, and Punishment.Daniel J. Miller - 2020 - American Journal of Bioethics Neuroscience 1 (11):72-74.
    An ongoing debate in the philosophy of action concerns the prevalence of moral luck: instances in which an agent’s moral responsibility is due, at least in part, to factors beyond his control. I point to a unique problem of moral luck for agents who depend upon Brain Computer Interfaces (BCIs) for bodily movement. BCIs may misrecognize a voluntarily formed distal intention (e.g., a plan to commit some illicit act in the future) as a control command to perform some overt (...)
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  28.  69
    Interactive Perception for Amplification of Intended Behavior in Complex Noisy Environments.Yasser Mohammad & Toyoaki Nishida - 2009 - AI and Society 23 (2):167-186.
    The detection of a human’s intended behavior is one of the most important skills that a social robot should have in order to become acceptable as a part of human society, because humans are used to understand the actions of other humans in a goal-directed manner and they will expect the social robot to behave similarly. A breakthrough in this area can advance several research branches related to social intelligence such as learning by imitation and mutual adaptation. To achieve (...)
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  29.  17
    Nucleation Behaviour and Anomalous Eutectic Formation in Highly Undercooled Fe 2 O 3 -La 2 O 3 Eutectic Melts.Mingjun Li, Kosuke Nagashio & Kazuhiko Kuribayashi - 2003 - Philosophical Magazine 83 (9):1095-1109.
    Employing an aero-acoustic levitator, the Fe 2 O 3 -16.5 mol% La 2 O 3 eutectic alloy was levitated, melted, undercooled and then solidified under a containerless condition when a continuous laser beam heating system was incorporated. By revealing the surface and cross-sectional microstructures, copious nucleation is confirmed to take place in the undercooled melts solidified by either an external seeding or spontaneous crystallization. The nucleation behaviour of eutectic alloys is summarized, indicating that copious nucleation may be an intrinsic attribute (...)
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  30.  1
    Lithium Iron Phosphate Power Cell Fault Detection System Based on Hybrid Intelligent System.José Luis Casteleiro-Roca, Héctor Quintián, José Luis Calvo-Rolle, Juan-Albino Méndez-Pérez, Francisco Javier Perez-Castelo & Emilio Corchado - forthcoming - Logic Journal of the IGPL.
    Nowadays, batteries play an important role in a lot of different applications like energy storage, electro-mobility, consumer electronic and so on. All the battery types have a common factor that is their complexity, independently of its nature. Usually, the batteries have an electrochemical nature. Several different test are accomplished to check the batteries performance, and commonly, it is predictable how they work depending of their technology. The present research describes the hybrid intelligent system created to accomplish fault detection over a (...)
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  31.  25
    Cell Sociology and the Problem of Position Effect: Pattern Formation, Origin and Role of Gradients.Rosine Chandebois - 1977 - Acta Biotheoretica 26 (4):203-238.
    The control of pattern formation and the significance of gradients is reconsidered on the basis of the concept of cell sociology (which takes into account continuous exchange of information between cells and the possibility of autonomous progression in differentiation). Not all traits of a pattern are imposed by a single prepattern, which would be an organized molecular framework or a gradient. Patterns are unfolded in steps; these are readjustments of a cell population to intrinsic and extrinsic changes in (...)
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  32.  35
    Proliferating Patent Problems with Human Embryonic Stem Cell Research?Matthew Herder - 2006 - Journal of Bioethical Inquiry 3 (1-2):69-79.
    The scientific challenges and ethical controversies facing human embryonic stem cell (hESC) research continue to command attention. The issues posed by patenting hESC technologies have, however, largely failed to penetrate the discourse, much less result in political action. This paper examines U.S. and European patent systems, illustrating discrepancies in the patentability of hESC technologies and identifying potential negative consequences associated with efforts to make available hESC research tools for basic research purposes while at same time strengthening the position (...)
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  33.  13
    Correlating Velocity Patterns with Spatial Dynamics in Glioma Cell Migration.Thomas S. Deisboeck, Tim Demuth & Yuri Mansury - 2005 - Acta Biotheoretica 53 (3):181-190.
    Highly malignant neuroepithelial tumors are known for their extensive tissue invasion. Investigating the relationship between their spatial behavior and temporal patterns by employing detrended fluctuation analysis (DFA), we report here that faster glioma cell motility is accompanied by both greater predictability of the cells' migration velocity and concomitantly, more directionality in the cells' migration paths. Implications of this finding for both experimental and clinical cancer research are discussed.
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  34.  10
    Modelling Biological Gel Contraction by Cells: Mechanocellular Formulation and Cell Traction Force Quantification.I. Ferrenq, L. Tranqui, B. Vailhé, P. Y. Gumery & P. Tracqui - 1997 - Acta Biotheoretica 45 (3-4):267-293.
    Traction forces developed by most cell types play a significant role in the spatial organisation of biological tissues. However, due to the complexity of cell-extracellular matrix interactions, these forces are quantitatively difficult to estimate without explicitly considering cell properties and extracellular mechanical matrix responses. Recent experimental devices elaborated for measuring cell traction on extracellular matrix use cell deposits on a piece of gel placed between one fixed and one moving holder. We formulate here a mathematical (...)
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  35.  14
    Transmission of Mechanical Stresses Within the Cytoskeleton of Adherent Cells: A Theoretical Analysis Based on a Multi-Component Cell Model.Philippe Tracqui & Jacques Ohayon - 2004 - Acta Biotheoretica 52 (4):323-341.
    How environmental mechanical forces affect cellular functions is a central problem in cell biology. Theoretical models of cellular biomechanics provide relevant tools for understanding how the contributions of deformable intracellular components and specific adhesion conditions at the cell interface are integrated for determining the overall balance of mechanical forces within the cell. We investigate here the spatial distributions of intracellular stresses when adherent cells are probed by magnetic twisting cytometry. The influence of the cell nucleus stiffness (...)
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  36.  54
    Supplementary Motor Area Structure and Function: Review and Hypotheses.Gary Goldberg - 1985 - Behavioral and Brain Sciences 8 (4):567-588.
  37.  16
    The Physiological Role of Hormones in Saliva.Michael Gröschl - 2009 - Bioessays 31 (8):843-852.
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  38.  13
    Profitable Exchanges for Scientists: The Case of Swedish Human Embryonic Stem Cell Research. [REVIEW]Anders Persson, Sven Hemlin & Stellan Welin - 2007 - Health Care Analysis 15 (4):291-304.
    In this article two inter-related issues concerning the ongoing commercialisation of biomedical research are analyzed. One aim is to explain how scientists and clinicians at Swedish public institutions can make profits, both commercially and scientifically, by controlling rare human biological material, like embryos and embryonic stem cell lines. This control in no way presupposes legal ownership or other property rights as an initial condition. We show how ethically sensitive material (embryos and stem cell lines) have been used in (...)
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  39. Kant, Morality, and Hell.James Edwin Mahon - 2015 - In Robert Arp & Ben McCraw (eds.), The Concept of Hell. Palgrave-Macmillan. pp. 113-126.
    In this paper I argue that, although Kant argues that morality is independent of God (and hence, agrees with the Euthyphro), and rejects Divine Command Theory (or Theological Voluntarism), he believes that all moral duties are also the commands of God, who is a moral being, and who is morally required to punish those who transgress the moral law: "God’s justice is the precise allocation of punishments and rewards in accordance with men’s good or bad behavior." However, since (...)
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  40. From Molecules to Behavior and the Clinic: Integration in Chronobiology.William Bechtel - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):493-502.
    Chronobiology, especially the study of circadian rhythms, provides a model scientific field in which philosophers can study how investigators from a variety of disciplines working at different levels of organization are each contributing to a multi-level account of the responsible mechanism. I focus on how the framework of mechanistic explanation integrates research designed to decompose the mechanism with efforts directed at recomposition that relies especially on computation models. I also examine how recently the integration has extended beyond basic research to (...)
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  41.  61
    From Cell-Surface Receptors to Higher Learning: A Whole World of Experience.Karola Stotz & Colin Allen - 2012 - In Philosophy of Behavioral Biology, eds, Katie Plaisance and Thomas Reydon. Boston: Springer. pp. 85-123.
    In the last decade it has become en vogue for cognitive comparative psychologists to study animal behavior in an ‘integrated’ fashion to account for both the ‘innate’ and the ‘acquired’. We will argue that these studies, instead of really integrating the concepts of ‘nature’ and ‘nurture’, rather cement this old dichotomy. They combine empty nativist interpretation of behavior systems with blatantly environmentalist explanations of learning. We identify the main culprit as the failure to take development seriously. While in (...)
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  42.  16
    Amoebae as Exemplary Cells: The Protean Nature of an Elementary Organism. [REVIEW]Andrew Reynolds - 2008 - Journal of the History of Biology 41 (2):307 - 337.
    In the nineteenth century protozoology and early cell biology intersected through the nexus of Darwin's theory of evolution. As single-celled organisms, amoebae offered an attractive focus of study for researchers seeking evolutionary relationships between the cells of humans and other animals, and their primitive appearance made them a favourite model for the ancient ancestor of all living things. Their resemblance to human and other metazoan cells made them popular objects of study among morphologists, physiologists, and even those investigating animal (...)
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  43.  12
    From Molecules to Behavior and the Clinic: Integration in Chronobiology.William Bechtel - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):493-502.
    Chronobiology, especially the study of circadian rhythms, provides a model scientific field in which philosophers can study how investigators from a variety of disciplines working at different levels of organization are each contributing to a multi-level account of the responsible mechanism. I focus on how the framework of mechanistic explanation integrates research designed to decompose the mechanism with efforts directed at recomposition that relies especially on computation models. I also examine how recently the integration has extended beyond basic research to (...)
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  44.  2
    Engaging the Adaptive Subject: Learning Evolution Beyond the Cell Walls.Ramsey Affifi - forthcoming - Biological Theory:1-15.
    According to the modern synthesis, evolution is the gradual change of gene frequencies in a population. The MS is closely allied to adaptationist explanations of phenotypes, where organismic form and behavior is treated as previously selected for and owes its genesis to some remote past. However, some new theories of evolution broadly aligned with the extended evolutionary synthesis, in particular developmental plasticity theory and niche construction theory, foreground the fact that evolution is sometimes much more rapid than previously imagined, (...)
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  45.  29
    Unethical Business Behavior in Post-Communist Russia: Origins and Trends.Alexander Filatov - 1994 - Business Ethics Quarterly 4 (1):11-15.
    Russian is presently in a transition stage between the old centrally administered command economy and a market economy. The result is uncertainty and instability. In such a situation there is both little room and little concern for business ethics. The objective conditions for this include distortions in the systems of supply and exchange, political instability, and judicial ineffectiveness. The subjective conditions include the breakdown of morality under the communist system, and the wide acceptance of “wild” capitalism as a necessary (...)
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  46.  12
    Unethical Business Behavior in Post-Communist Russia: Origins and Trends.Alexander Filatov - 1994 - Business Ethics Quarterly 4 (1):11-15.
    Russian is presently in a transition stage between the old centrally administered command economy and a market economy. The result is uncertainty and instability. In such a situation there is both little room and little concern for business ethics. The objective conditions for this include distortions in the systems of supply and exchange, political instability, and judicial ineffectiveness. The subjective conditions include the breakdown of morality under the communist system, and the wide acceptance of “wild” capitalism as a necessary (...)
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  47.  20
    Stability Properties of Proliferatively Coupled Cell Replication Models.A. Lasotal, K. Loskot & M. C. Mackey - 1991 - Acta Biotheoretica 39 (1):1-14.
    To address the possibility that proliferative disorders may originate from interactions between multiple populations of proliferating and maturing cells, we formulate a model for this process as a set of coupled nonlinear first order partial differential equations. Using recent results for the asymptotic behaviour of the solutions to this model, we demonstrate that there exists a region of coupling coefficients, maturation rates, and proliferation rates that will guarantee the stable coexistence of coupled cellular populations. The analysis shows that increases in (...)
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  48. Традиційне Та Новаційне В Протидії Злочинним Проявам У Радянській Україні За Умов Лібералізації Суспільства Хрущовської Доби.Oksana Mikheieva - 2013 - Схід 6 (126):232-237.
    State policy in the field of law enforcement during the Khrushchev's period wasn't a stabile. The first wave of changes was associated with the abolition of some legislative acts of the Stalinist period, a significant softening of punitive line, narrowing of the scope of capital punishment, empowerment convicted people etc. On the one hand, these steps are partially rehabilitating the Soviet law enforcement. On the other hand, government actions were unreasoned and populist, designed for quick political effect. The next wave (...)
     
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  49.  13
    Mesenchymal Stem Cells for Systemic Therapy: Shotgun Approach or Magic Bullets?Susan M. Millard & Nicholas M. Fisk - 2013 - Bioessays 35 (3):173-182.
    Given their heterogeneity and lack of defining markers, it is surprising that multipotent mesenchymal stem/stromal cells (MSCs) have attracted so much translational attention, especially as increasing evidence points to their predominant effect being not by donor differentiation but via paracrine mediators and exosomes. Achieving long-term MSC donor chimerism for treatment of chronic disease remains a challenge, requiring enhanced MSC homing/engraftment properties and manipulation of niches to direct MSC behaviour. Meanwhile advances in nanoparticle technology are furthering the development of MSCs as (...)
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  50.  14
    Human Pheromones and Food Odors: Epigenetic Influences on the Socioaffective Nature of Evolved Behaviors.James V. Kohl - 2012 - Socioaffective Neuroscience and Psychology 2.
    Background: Olfactory cues directly link the environment to gene expression. Two types of olfactory cues, food odors and social odors, alter genetically predisposed hormone-mediated activity in the mammalian brain. Methods: The honeybee is a model organism for understanding the epigenetic link from food odors and social odors to neural networks of the mammalian brain, which ultimately determine human behavior. Results: Pertinent aspects that extend the honeybee model to human behavior include bottom-up followed by top-down gene, cell, tissue, (...)
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