Results for 'developmental biology'

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  1.  59
    Evolutionary Morphology, Innovation, and the Synthesis of Evolutionary and Developmental Biology.Alan C. Love - 2001 - Biology and Philosophy 18 (2):309-345.
    One foundational question in contemporarybiology is how to `rejoin evolution anddevelopment. The emerging research program(evolutionary developmental biology or`evo-devo) requires a meshing of disciplines,concepts, and explanations that have beendeveloped largely in independence over the pastcentury. In the attempt to comprehend thepresent separation between evolution anddevelopment much attention has been paid to thesplit between genetics and embryology in theearly part of the 20th century with itscodification in the exclusion of embryologyfrom the Modern Synthesis. This encourages acharacterization of evolutionary developmentalbiology as (...)
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  2. The Proximate–Ultimate Distinction and Evolutionary Developmental Biology: Causal Irrelevance Versus Explanatory Abstraction.Massimo Pigliucci & Raphael Scholl - 2015 - Biology and Philosophy 30 (5):653-670.
    Mayr’s proximate–ultimate distinction has received renewed interest in recent years. Here we discuss its role in arguments about the relevance of developmental to evolutionary biology. We show that two recent critiques of the proximate–ultimate distinction fail to explain why developmental processes in particular should be of interest to evolutionary biologists. We trace these failures to a common problem: both critiques take the proximate–ultimate distinction to neglect specific causal interactions in nature. We argue that this is implausible, and (...)
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  3. How Development Changes Evolution: Conceptual and Historical Issues in Evolutionary Developmental Biology.Stavros Ioannidis - 2008 - Biology and Philosophy 23 (4):567-578.
    Evolutionary developmental biology (Evo-Devo) is a new and rapidly developing field of biology which focuses on questions in the intersection of evolution and development and has been seen by many as a potential synthesis of these two fields. This synthesis is the topic of the books reviewed here. Integrating Evolution and Development (edited by Roger Sansom and Robert Brandon), is a collection of papers on conceptual issues in Evo-Devo, while From Embryology to Evo-Devo (edited by Manfred Laubichler (...)
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  4.  47
    How to Be an Anti-Reductionist About Developmental Biology: Response to Laubichler and Wagner.Greg Frost-Arnold - 2004 - Biology and Philosophy 19 (1):75-91.
    Alexander Rosenberg recently claimed (1997) that developmental biology is currently being reduced to molecular biology. cite several concrete biological examples that are intended to impugn Rosenberg's claim. I first argue that although Laubichler and Wagner's examples would refute a very strong reductionism, a more moderate reductionism would escape their attacks. Next, taking my cue from the antireductionist's perennial stress on the importance of spatial organization, I describe one form an empirical finding that refutes this moderate reductionism would (...)
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  5.  9
    Ecological Developmental Biology: Interpreting Developmental Signs.Scott F. Gilbert - 2016 - Biosemiotics 9 (1):51-60.
    Developmental biology is a theory of interpretation. Developmental signals are interpreted differently depending on the previous history of the responding cell. Thus, there is a context for the reception of a signal. While this conclusion is obvious during metamorphosis, when a single hormone instructs some cells to proliferate, some cells to differentiate, and other cells to die, it is commonplace during normal development. Paracrine factors such as BMP4 can induce apoptosis, proliferation, or differentiation depending upon the history (...)
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  6.  89
    How Molecular is Molecular Developmental Biology? A Reply to Alex Rosenberg's Reductionism Redux: Computing the Embryo. [REVIEW]Manfred D. Laubichler & Günter P. Wagner - 2001 - Biology and Philosophy 16 (1):53-68.
    This paper argues in defense of theanti-reductionist consensus in the philosophy ofbiology. More specifically, it takes issues with AlexRosenberg's recent challenge of this position. Weargue that the results of modern developmentalgenetics rather than eliminating the need forfunctional kinds in explanations of developmentactually reinforce their importance.
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  7.  9
    [The work of Richard Goldschmidt: an attempt at a synthesis of genetics, developmental biology, and evolutionary theory surrounding the concept of homeosis].S. Schmitt - 1999 - Revue d'Histoire des Sciences 53 (3-4):381-399.
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  8.  88
    Evolutionary Developmental Biology and the Limits of Philosophical Accounts of Mechanistic Explanation.Ingo Brigandt - 2015 - In P.-A. Braillard & C. Malaterre (eds.), Explanation in Biology: An Enquiry into the Diversity of Explanatory Patterns in the Life Sciences. Springer. pp. 135–173.
    Evolutionary developmental biology (evo-devo) is considered a ‘mechanistic science,’ in that it causally explains morphological evolution in terms of changes in developmental mechanisms. Evo-devo is also an interdisciplinary and integrative approach, as its explanations use contributions from many fields and pertain to different levels of organismal organization. Philosophical accounts of mechanistic explanation are currently highly prominent, and have been particularly able to capture the integrative nature of multifield and multilevel explanations. However, I argue that evo-devo demonstrates the (...)
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  9.  78
    Homology in Comparative, Molecular, and Evolutionary Developmental Biology: The Radiation of a Concept.Ingo Brigandt - 2003 - Journal of Experimental Zoology (Molecular and Developmental Evolution) 299:9-17.
    The present paper analyzes the use and understanding of the homology concept across different biological disciplines. It is argued that in its history, the homology concept underwent a sort of adaptive radiation. Once it migrated from comparative anatomy into new biological fields, the homology concept changed in accordance with the theoretical aims and interests of these disciplines. The paper gives a case study of the theoretical role that homology plays in comparative and evolutionary biology, in molecular biology, and (...)
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  10.  70
    How Developmental is Evolutionary Developmental Biology?Jason Scott Robert - 2002 - Biology and Philosophy 17 (5):591-611.
    Evolutionary developmental biology (evo-devo) offers both an account of developmental processes and also new integrative frameworks for analyzing interactions between development and evolution. Biologists and philosophers are keen on evo-devo in part because it appears to offer a comfort zone between, on the one hand, what some take to be the relative inability of mainstream evolutionary biology to integrate a developmental perspective; and, on the other hand, what some take to be more intractable syntheses of (...)
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  11.  4
    Teaching Evolutionary Developmental Biology: Concepts, Problems, and Controversy.A. C. Love - 2013 - In K. Kampourakis (ed.), Philosophy of Biology: A Companion for Educators. Springer. pp. 323-341.
    Although sciences are often conceptualized in terms of theory confirmation and hypothesis testing, an equally important dimension of scientific reasoning is the structure of problems that guide inquiry. This problem structure is evident in several concepts central to evolutionary developmental biology (Evo-devo)—constraints, modularity, evolvability, and novelty. Because problems play an important role in biological practice, they should be included in biological pedagogy, especially when treating the issue of scientific controversy. A key feature of resolving controversy is synthesizing methodologies (...)
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  12. Conceptual Change and Evolutionary Developmental Biology.A. C. Love - 2015 - In Conceptual Change in Biology: Scientific and Philosophical Perspectives on Evolution and Development. Springer. pp. 1-54.
    The 1981 Dahlem conference was a catalyst for contemporary evolutionary developmental biology (Evo-devo). This introductory chapter rehearses some of the details of the history surrounding the original conference and its associated edited volume, explicates the philosophical problem of conceptual change that provided the rationale for a workshop devoted to evaluating the epistemic revisions and transformations that occurred in the interim, explores conceptual change with respect to the concept of evolutionary novelty, and highlights some of the themes and patterns (...)
     
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  13.  29
    Stages in the Development of a Model Organism as a Platform for Mechanistic Models in Developmental Biology: Zebrafish, 1970–2000.Robert Meunier - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (2):522-531.
    Model organisms became an indispensable part of experimental systems in molecular developmental and cell biology, constructed to investigate physiological and pathological processes. They are thought to play a crucial role for the elucidation of gene function, complementing the sequencing of the genomes of humans and other organisms. Accordingly, historians and philosophers paid considerable attention to various issues concerning this aspect of experimental biology. With respect to the representational features of model organisms, that is, their status as models, (...)
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  14. Two Concepts of Constraint: Adaptationism and the Challenge From Developmental Biology.Ron Amundson - 1994 - Philosophy of Science 61 (4):556-578.
    The so-called "adaptationism" of mainstream evolutionary biology has been criticized from a variety of sources. One, which has received relatively little philosophical attention, is developmental biology. Developmental constraints are said to be neglected by adaptationists. This paper explores the divergent methodological and explanatory interests that separate mainstream evolutionary biology from its embryological and developmental critics. It will focus on the concept of constraint itself; even this central concept is understood differently by the two sides (...)
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  15.  4
    Developmental Biology.A. C. Love - 2015 - The Stanford Encyclopedia of Philosophy.
    Developmental biology is the science of explaining how a variety of interacting processes generate an organism’s heterogeneous shapes, size, and structural features that arise on the trajectory from embryo to adult, or more generally throughout a life cycle. It represents an exemplary area of contemporary experimental biology that focuses on phenomena that have puzzled natural philosophers and scientists for more than two millennia.
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  16.  17
    Developmental Biology, Natural Selection, and the Conceptual Boundaries of the Modern Evolutionary Synthesis.David J. Depew & Bruce H. Weber - 2017 - Zygon 52 (2):468-490.
    Using the evolution of the stickleback family of subarctic fish as a touchstone, we explore the effect of new discoveries about regulatory genetics, developmental plasticity, and epigenetic inheritance on the conceptual foundations of the Modern Evolutionary Synthesis. Identifying the creativity of natural selection as the hallmark of the Modern Synthesis, we show that since its inception its adherents have pursued a variety of research projects that at first seemed to conflict with its principles, but were accommodated. We situate challenges (...)
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  17. The Erotetic Organization of Developmental Biology.A. C. Love - 2014 - In A. Minelli & T. Pradeu (eds.), Towards a Theory of Development. Oxford University Press. pp. 33–55.
    Developmental biology is the science of explaining how a variety of interacting processes generate the heterogeneous shapes, size, and structural features of an organism as it develops rom embryo to adult, or more generally throughout its life cycle (Love, 2008b; Minelli, 2011a). Although it is commonplace in philosophy to associate sciences with theories such that the individuation of a science is dependent on a constitutive theory or group of models, it is uncommon to find presentations of developmental (...)
     
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  18. Generative Entrenchment and an Evolutionary Developmental Biology for Culture.William C. Wimsatt - 2006 - Behavioral and Brain Sciences 29 (4):364-366.
    Mesoudi et al.'s new synthesis for cultural evolution closely parallels the evolutionary synthesis of Neo-Darwinism. It too draws inspiration from population genetics, recruits other fields, and, unfortunately, also ignores development. Enculturation involves many serially acquired skills and dependencies that allow us to build a rich cumulative culture. The newer synthesis, evolutionary developmental biology, provides a key tool, generative entrenchment, to analyze them. (Published Online November 9 2006).
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  19. Evolutionary Developmental Biology, the Human Life Course, and Transpersonal Experience.Edward Dale - 2011 - Journal of Mind and Behavior 32 (4):277.
    This paper explicates secular psychodynamic growth through the life time and meditation as routes to the transpersonal from the perspective of evolutionary developmental biology, based around a multi-line model of growth. A multi-line model raises many significant points for a transpersonal audience. Such models have been pioneered by Hunt. When set on the footing of evolutionary developmental biology and nonlinear dynamics these kind of models become all the more cogent, penetrating and far reaching, validating plurality and (...)
     
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  20.  10
    The Significance and Scope of Evolutionary Developmental Biology: A Vision for the 21st Century.A. P. Moczek, K. E. Sears, A. Stollewerk, P. J. Wittkopp, P. Diggle, I. Dworkin, C. Ledon-Rettig, D. Q. Mattus, S. Roth, E. Abouheif, F. D. Brown, C.-H. Chiu, C. S. Cohen & A. W. De Tomaso - 2015 - Evolution & Development 17:198–219.
    Evolutionary developmental biology (evo-devo) has undergone dramatic transformations since its emergence as a distinct discipline. This paper aims to highlight the scope, power, and future promise of evo-devo to transform and unify diverse aspects of biology. We articulate key questions at the core of eleven biological disciplines—from Evolution, Development, Paleontology, and Neurobiology to Cellular and Molecular Biology, Quantitative Genetics, Human Diseases, Ecology, Agriculture and Science Education, and lastly, Evolutionary Developmental Biology itself—and discuss why evo-devo (...)
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  21.  1
    The Grassblade Beyond Newton: The Pragmatizing of Kant for Evolutionary-Developmental Biology.Lenny Moss & Stuart A. Newman - 2015 - Lebenswelt: Aesthetics and Philosophy of Experience 7:94-111.
    Much of the philosophical attention directed to Kant’s intervention into biology has been directed toward Kant’s idea of a transcendental limit upon what can be understood constitutively. Kant’s own wider philosophical practice, however, was principally oriented toward solving problems and the scientific benefits of his methodology of teleology have been largely underappreciated, at least in the English language literature. This paper suggests that all basic biology has had, and continues to have, a need for some form of heuristic (...)
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  22. Evolutionary Developmental Biology: Philosophical Issues.Alan Love - 2015 - In T. Heams, Philippe Huneman, L. Lecointre & Michael Silberstein (eds.), Handbook of Evolutionary Thinking in the Sciences. Berlin: Springer. pp. 265-283.
    Evolutionary developmental biology (Evo-devo) is a loose conglomeration of research programs in the life sciences with two main axes: (a) the evolution of development, or inquiry into the pattern and processes of how ontogeny varies and changes over time; and, (b) the developmental basis of evolution, or inquiry into the causal impact of ontogenetic processes on evolutionary trajectories—both in terms of constraint and facilitation. Philosophical issues are found along both axes surrounding concepts such as evolvability, novelty, and (...)
     
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  23.  11
    Rethinking Causation in Cancer with Evolutionary Developmental Biology.Katherine E. Liu - 2017 - Biological Theory 13 (4):228-242.
    Despite the productivity of basic cancer research, cancer continues to be a health burden to society because this research has not yielded corresponding clinical applications. Many proposed solutions to this dilemma have revolved around implementing organizational and policy changes related to cancer research. Here I argue for a different solution: a new conceptualization of causation in cancer. Neither the standard molecular biomarker approaches nor evolutionary biology approaches to cancer fully capture its complex causal dynamics, even when considered jointly. These (...)
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  24. A Theory of Conceptual Advance: Explaining Conceptual Change in Evolutionary, Molecular, and Evolutionary Developmental Biology.Ingo Brigandt - 2006 - Dissertation, University of Pittsburgh
    The theory of concepts advanced in the dissertation aims at accounting for a) how a concept makes successful practice possible, and b) how a scientific concept can be subject to rational change in the course of history. Traditional accounts in the philosophy of science have usually studied concepts in terms only of their reference; their concern is to establish a stability of reference in order to address the incommensurability problem. My discussion, in contrast, suggests that each scientific concept consists of (...)
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  25.  77
    The Philosophy of Molecular and Developmental Biology.Paul Edmund Griffiths - unknown
    Philosophical discussion of molecular and developmental biology began in the late 1960s with the use of genetics as a test case for models of theory reduction. With this exception, the theory of natural selection remained the main focus of philosophy of biology until the late 1970s. It was controversies in evolutionary theory over punctuated equilibrium and adaptationism that first led philosophers to examine the concept of developmental constraint. Developmental biology also gained in prominence in (...)
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  26.  46
    Scientific Exchange: Jacques Loeb (1859–1924) and Emil Godlewski (1875–1944) as Representatives of a Transatlantic Developmental Biology[REVIEW]Heiner Fangerau & Irmgard Müller - 2007 - Studies in History and Philosophy of Science Part C 38 (3):608-617.
    The German–American physiologist Jacques Loeb (1859–1924) and the Polish embryologist Emil Godlewski, jr. (1875–1944) contributed many valuable works to the body of developmental biology. Jacques Loeb was world famous at the beginning of the twentieth century for his development and demonstration of artificial parthenogenesis in 1899 and his experiments on regeneration. He served as a role model for the younger Polish experimenter Emil Godlewski, who began his career as a researcher like Loeb at the Zoological Station in Naples. (...)
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  27. Crystals, Fabrics, and Fields: Metaphors of Organicism in Twentieth-Century Developmental Biology.Donna Jeanne Haraway - 1976 - Yale University Press.
  28.  32
    The Use of Natural Kinds in Evolutionary Developmental Biology.Jessica Bolker - 2013 - Biological Theory 7 (2):121-129.
    Evolutionary developmental biologists categorize many different kinds of things, from ontogenetic stages to modules of gene activity. The process of categorization—the establishment of “kinds”—is an implicit part of describing the natural world in consistent, useful ways, and has an essentially practical rather than philosophical basis. Kinds commonly serve one of three purposes: they may function (1) as practical tools for communication; (2) to support prediction and generalization; or (3) as a basis for theoretical discussions. Beyond the minimal requirement that (...)
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  29.  38
    Plants and the Conceptual Articulation of Evolutionary Developmental Biology.Francisco Vergara-Silva - 2003 - Biology and Philosophy 18 (2):249-284.
  30.  20
    Readers of the Book of Life: Contextualizing Developmental Evolutionary Biology.Anton Markoš - 2002 - Oxford University Press.
    This is a wide ranging and deeply learned examination of evolutionary developmental biology, and the foundations of life from the perspective of information theory. Hermeneutics was a method developed in the humanities to achieve understanding, in a given context, of texts, history, and artwork. In Readers of the Book of Life, the author shows that living beings are also hermeneutical interpreters of genetics texts saved in DNA; an interpretation based on the past experience of the cell (cell lineage, (...)
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  31.  12
    Expanding the Temporal Dimensions of Developmental Biology: The Role of Environmental Agents in Establishing Adult-Onset Phenotypes.Scott F. Gilbert - 2011 - Biological Theory 6 (1):65-72.
  32. Evolutionary Developmental Biology Offers a Significant Challenge to the Neo-Darwinian Paradigm.Manfred D. Laubichler - 2010 - In Francisco José Ayala & Robert Arp (eds.), Contemporary Debates in Philosophy of Biology. Wiley-Blackwell.
  33. Exporting Causal Knowledge in Evolutionary and Developmental Biology.Sandra D. Mitchell - 2008 - Philosophy of Science 75 (5):697-706.
    In this article I consider the challenges for exporting causal knowledge raised by complex biological systems. In particular, James Woodward’s interventionist approach to causality identified three types of stability in causal explanation: invariance, modularity, and insensitivity. I consider an example of robust degeneracy in genetic regulatory networks and knockout experimental practice to pose methodological and conceptual questions for our understanding of causal explanation in biology. †To contact the author, please write to: Department of History and Philosophy of Science, University (...)
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  34. How the Mind Grows: A Developmental Perspective on the Biology of Cognition.Paul E. Griffiths & Karola Stotz - 2000 - Synthese 122 (1-2):29-51.
    The 'developmental systems' perspective in biology is intended to replace the idea of a genetic program. This new perspective is strongly convergent with recent work in psychology on situated/embodied cognition and on the role of external 'scaffolding' in cognitive development. Cognitive processes, including those which can be explained in evolutionary terms, are not 'inherited' or produced in accordance with an inherited program. Instead, they are constructed in each generation through the interaction of a range of developmental resources. (...)
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  35. Evolutionary Developmental Biology Does Not Offer a Significant Challenge to the Neo-Darwinian Paradigm.Alessandro Minelli - 2010 - In Francisco José Ayala & Robert Arp (eds.), Contemporary Debates in Philosophy of Biology. Wiley-Blackwell.
  36. Keywords and Concepts in Evolutionary Developmental Biology.Brian K. Hall & Wendy M. Olson - 2004 - Journal of the History of Biology 37 (2):406-408.
  37. Keywords and Concepts in Evolutionary Developmental Biology.Brian Hall & Wendy Olson - 2007 - Journal of the History of Biology 40 (4):776-777.
     
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  38. Evolutionary Developmental Biology.Manfred D. Laubichler - 2007 - In David L. Hull & Michael Ruse (eds.), The Cambridge Companion to the Philosophy of Biology. Cambridge University Press.
  39.  43
    The Concept of Morphospaces in Evolutionary and Developmental Biology: Mathematics and Metaphors.Philipp Mitteroecker & Simon M. Huttegger - 2009 - Biological Theory 4 (1):54-67.
    Formal spaces have become commonplace conceptual and computational tools in a large array of scientific disciplines, including both the natural and the social sciences. Morphological spaces are spaces describing and relating organismal phenotypes. They play a central role in morphometrics, the statistical description of biological forms, but also underlie the notion of adaptive landscapes that drives many theoretical considerations in evolutionary biology. We briefly review the topological and geometrical properties of the most common morphospaces in the biological literature. In (...)
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  40.  74
    What Developmental Biology Can Tell Us About Innateness.Gary F. Marcus - 2005 - In Peter Carruthers, Stephen Laurence & Stephen Stich (eds.), The Innate Mind: Structure and Contents. New York: Oxford University Press New York. pp. 23.
    This chapter examines an apparent tension created by recent research on neurological development and genetics on the one hand and cognitive development on the other. It considers what it might mean for intrinsic signals to guide the initial establishment of functional architecture. It argues that an understanding of the mechanisms by which the body develops can inform our understanding of the mechanisms by which the brain develops. It cites the view of developmental neurobiologists Fukuchi-Shimogori and Grove, that the patterning (...)
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  41.  11
    Making Sense of Life: Explanation in Developmental Biology.E. F. Keller - 2000 - In Richard Creath & Jane Maienschein (eds.), Biology and Epistemology. Cambridge University Press. pp. 244--260.
  42.  4
    Competing Epistemologies and Developmental Biology.Jane Maienschein - 2000 - In Richard Creath & Jane Maienschein (eds.), Biology and Epistemology. Cambridge University Press. pp. 122--137.
  43.  22
    Reframing Developmental Biology and Building Evolutionary Theory's New Synthesis.Alfred I. Tauber - 2010 - Perspectives in Biology and Medicine 53 (2):257-270.
  44.  2
    In Situ Hybridization: Application to Developmental Biology and Medicine.E. D. Garber - 1991 - Perspectives in Biology and Medicine 35 (1):156-156.
  45. Lehrman's Dictum: Information and Explanation in Developmental Biology.Paul E. Griffiths - 2013 - Developmental Psychobiology 55 (1):22--32.
  46.  72
    Information in Genetics and Developmental Biology: Comments on Maynard Smith.Sahotra Sarkar - 2000 - Philosophy of Science 67 (2):208-213.
  47.  30
    Model Systems in Developmental Biology.Jessica A. Bolker - 1995 - Bioessays 17 (5):451-455.
  48. Evolutionary Developmental Biology Meets Levels of Selection: Modular Integration or Competition, or Both?Rasmus Grønfeldt Winther - 2005 - In Werner Callebaut & Diego Rasskin-Gutman (eds.), Modularity. Understanding the Development and Evolution of Natural Complex Systems. MIT Press.
  49.  31
    Bridging the Gap Between Developmental Systems Theory and Evolutionary Developmental Biology†.Jason Scott Robert, Brian K. Hall & Wendy M. Olson - 2001 - Bioessays 23 (10):954-962.
  50.  5
    The Diversification of Developmental Biology.Nathan Crowe, Michael R. Dietrich, Beverly S. Alomepe, Amelia F. Antrim, Bay Lauris ByrneSim & Yi He - 2015 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 53:1-15.
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