Results for 'epigenetic mark'

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  1.  21
    N6-Methyladenine Functions as a Potential Epigenetic Mark in Eukaryotes.Qinmiao Sun, Shoujun Huang, Xiaona Wang, Yuanxiang Zhu, Zhenping Chen & Dahua Chen - 2015 - Bioessays 37 (11):1155-1162.
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  2.  90
    Beyond the Baldwin Effect: James Mark Baldwin's 'Social Heredity', Epigenetic Inheritance, and Niche Construction.Paul E. Griffiths - 2001 - In Bruce H. Weber & David J. Depew (eds.), Evolution and Learning: The Baldwin Effect Reconsidered. MIT Press. pp. 193--215.
    I argue that too much attention has been paid to the Baldwin effect. George Gaylord Simpson was probably right when he said that the effect is theoretically possible and may have actually occurred but that this has no major implications for evolutionary theory. The Baldwin effect is not even central to Baldwin's own account of social heredity and biology-culture co-evolution, an account that in important respects resembles the modern ideas of epigenetic inheritance and niche-construction.
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  3.  49
    The 'Kinetochore Maintenance Loop'—The Mark of Regulation?William R. A. Brown & Zheng-yao Xu - 2009 - Bioessays 31 (2):228-236.
  4.  12
    Adenine Methylation in Eukaryotes: Apprehending the Complex Evolutionary History and Functional Potential of an Epigenetic Modification.Lakshminarayan M. Iyer, Dapeng Zhang & L. Aravind - 2016 - Bioessays 38 (1):27-40.
    While N6‐methyladenosine (m6A) is a well‐known epigenetic modification in bacterial DNA, it remained largely unstudied in eukaryotes. Recent studies have brought to fore its potential epigenetic role across diverse eukaryotes with biological consequences, which are distinct and possibly even opposite to the well‐studied 5‐methylcytosine mark. Adenine methyltransferases appear to have been independently acquired by eukaryotes on at least 13 occasions from prokaryotic restriction‐modification and counter‐restriction systems. On at least four to five instances, these methyltransferases were recruited as (...)
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  5.  45
    RNA Regulation of Epigenetic Processes.John S. Mattick, Paulo P. Amaral, Marcel E. Dinger, Tim R. Mercer & Mark F. Mehler - 2009 - Bioessays 31 (1):51-59.
    There is increasing evidence that dynamic changes to chromatin, chromosomes and nuclear architecture are regulated by RNA signalling. Although the precise molecular mechanisms are not well understood, they appear to involve the differential recruitment of a hierarchy of generic chromatin modifying complexes and DNA methyltransferases to specific loci by RNAs during differentiation and development. A significant fraction of the genome-wide transcription of non-protein coding RNAs may be involved in this process, comprising a previously hidden layer of intermediary genetic information that (...)
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  6.  31
    Epigenetic Exceptionalism.Mark A. Rothstein - 2013 - Journal of Law, Medicine and Ethics 41 (3):733-736.
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  7.  31
    Epigenetic Exceptionalism.Mark A. Rothstein - 2013 - Journal of Law, Medicine and Ethics 41 (3):733-736.
    This article considers the distinctive features of epigenetics and discusses whether, as a matter of ethics and law, epigenetics should be considered separate from genetics.
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  8.  92
    The Epigenetic Landscape in the Course of Time: Conrad Hal Waddington’s Methodological Impact on the Life Sciences.Jan Baedke - 2013 - Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):756-773.
    It seems that the reception of Conrad Hal Waddington’s work never really gathered speed in mainstream biology. This paper, offering a transdisciplinary survey of approaches using his epigenetic landscape images, argues that (i) Waddington’s legacy is much broader than is usually recognized—it is widespread across the life sciences (e.g. stem cell biology, developmental psychology and cultural anthropology). In addition, I will show that (ii) there exist as yet unrecognized heuristic roles, especially in model building and theory formation, which Waddington’s (...)
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  9. Epigenetic Landscaping: Waddington's Use of Cell Fate Bifurcation Diagrams. [REVIEW]Scott F. Gilbert - 1991 - Biology and Philosophy 6 (2):135-154.
    From the 1930s through the 1970s, C. H. Waddington attempted to reunite genetics, embryology, and evolution. One of the means to effect this synthesis was his model of the epigenetic landscape. This image originally recast genetic data in terms of embryological diagrams and was used to show the identity of genes and inducers and to suggest the similarities between embryological and genetic approaches to development. Later, the image became more complex and integrated gene activity and mutations. These revised (...) landscapes presented an image of how mutations could alter developmental pathways to yield larger phenotypic changes. These diagrams became less important as the operon became used to model differential gene regulation. (shrink)
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  10. Vitalism Without Metaphysics? Medical Vitalism in the Enlightenment.Charles T. Wolfe - 2008 - Science in Context 21 (4):461-463.
    This is the introduction to a special issue of 'Science in Context' on vitalism that I edited. The contents are: 1. Guido Giglioni — “What Ever Happened to Francis Glisson? Albrecht Haller and the Fate of Eighteenth-Century Irritability” 2. Dominique Boury— “Irritability and Sensibility: Two Key Concepts in Assessing the Medical Doctrines of Haller and Bordeu” 3. Tobias Cheung — “Regulating Agents, Functional Interactions, and Stimulus-Reaction-Schemes: The Concept of “Organism” in the Organic System Theories of Stahl, Bordeu and Barthez” 4. (...)
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  11. Where is My Mind? Mark Rowlands on the Vehicles of Cognition.Andreas Elpidorou - 2012 - Avant: Trends in Interdisciplinary Studies 3 (1):145-160.
    Do our minds extend beyond our brains? In a series of publications, Mark Rowlands has argued that the correct answer to this question is an affirmative one. According to Rowlands, certain types of operations on bodily and worldly structures should be considered to be proper and literal parts of our cognitive and mental processes. In this article, I present and critically evaluate Rowlands' position.
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  12. Review of Mark Sainsbury, Paradoxes. [REVIEW]Vincent C. Müller - 1994 - European Review of Philosophy 1:182-184.
  13. Intentionality, Consciousness, and the Mark of the Mental: Rorty’s Challenge.James Tartaglia - 2008 - The Monist 91 (2):324-346.
    Intentionality and phenomenal consciousness are the main candidates to provide a ‘ mark of the mental’. Rorty, who thinks the category ‘mental’ lacks any underlying unity, suggests a challenge to these positions: to explain how intentionality or phenomenal consciousness alone could generate a mental-physical contrast. I argue that a failure to meet Rorty’s challenge would present a serious indictment of the concept of mind, even though Rorty’s own position is untenable. I then argue that both intentionalism and proposals such (...)
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  14.  10
    Selezione organica ed eredità sociale. Sguardo sul pensiero evoluzionistico di James Mark Baldwin.Chiara Pertile - 2018 - Nóema 9.
    In the current evolutionary debate, the «Baldwin Effect» is increasingly mentioned. The aim of this article is to teoretically analyze the original form of this concept, initially called “organic selection”, through the thought of one of its main advocates: James Mark Baldwin. His evolutionary observations, almost forgotten in Modern Synthesis’s refolmulations of «Baldwin Effect», appear widely original in view of contemporary attempt to «extend» the darwinian paradigm.
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  15.  55
    Mark Twain y la verdad nociva.José Andrés Quintero Restrepo - 2012 - Escritos 20 (45):417-434.
    Samuel Langhorne Clemens o Mark Twain es el autor del Diario de Adán y Eva, Un yanki en la corte del rey Arturo, Las aventuras de Tom Sawyer, Las aventuras de Huckleberry Finn y otras. Este escritor norteamericano asumió la práctica literaria como un asunto que va más allá del entretenimiento: escribió para interpelar al lector. Y este detalle salta a la vista con un libro que rara veces es referenciado: Sobre la decadencia del arte de mentir, texto que (...)
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  16.  40
    Mark Twain y la verdad nociva.José Andrés Quintero Restrepo - 2012 - Escritos 20 (45):417-434.
    Samuel Langhorne Clemens o Mark Twain es el autor del Diario de Adán y Eva, Un yanki en la corte del rey Arturo, Las aventuras de Tom Sawyer, Las aventuras de Huckleberry Finn y otras. Este escritor norteamericano asumió la práctica literaria como un asunto que va más allá del entretenimiento: escribió para interpelar al lector. Y este detalle salta a la vista con un libro que rara veces es referenciado: Sobre la decadencia del arte de mentir, texto que (...)
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  17.  19
    DNA Methylation in Embryo Development: Epigenetic Impact of ART.Sebastian Canovas, Pablo J. Ross, Gavin Kelsey & Pilar Coy - 2017 - Bioessays 39 (11):1700106.
    DNA methylation can be considered a component of epigenetic memory with a critical role during embryo development, and which undergoes dramatic reprogramming after fertilization. Though it has been a focus of research for many years, the reprogramming mechanism is still not fully understood. Recent results suggest that absence of maintenance at DNA replication is a major factor, and that there is an unexpected role for TET3-mediated oxidation of 5mC to 5hmC in guarding against de novo methylation. Base-resolution and genome-wide (...)
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  18.  27
    Visual Metaphors in the Sciences: The Case of Epigenetic Landscape Images.Jan Baedke & Tobias Schöttler - 2016 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie:1-22.
    Recent philosophical analyses of the epistemic dimension of images in the sciences show a certain trend in acknowledging potential roles of these images beyond their merely decorative or pedagogical functions. We argue, however, that this new debate has yet paid little attention to a special type of pictures, we call ‘visual metaphor’, and its versatile heuristic potential in organizing data, supporting communication, and guiding research, modeling, and theory formation. Based on a case study of Conrad Hal Waddington’s epigenetic landscape (...)
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  19.  6
    Between Social and Biological Heredity: Cope and Baldwin on Evolution, Inheritance, and Mind.David Ceccarelli - 2019 - Journal of the History of Biology 52 (1):161-194.
    In the years of the post-Darwinian debate, many American naturalists invoked the name of Lamarck to signal their belief in a purposive and anti-Darwinian view of evolution. Yet Weismann’s theory of germ-plasm continuity undermined the shared tenet of the neo-Lamarckian theories as well as the idea of the interchangeability between biological and social heredity. Edward Drinker Cope, the leader of the so-called “American School,” defended his neo-Lamarckian philosophy against every attempt to redefine the relationship between behavior, development, and heredity beyond (...)
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  20.  5
    How Communication Between Nucleosomes Enables Spreading and Epigenetic Memory of Histone Modifications.Fabian Erdel - 2017 - Bioessays 39 (12):1700053.
    Nucleosomes “talk” to each other about their modification state to form extended domains of modified histones independently of the underlying DNA sequence. At the same time, DNA elements promote modification of nucleosomes in their vicinity. How do these site-specific and histone-based activities act together to regulate spreading of histone modifications along the genome? How do they enable epigenetic memory to preserve cell identity? Many models for the dynamics of repressive histone modifications emphasize the role of strong positive feedback loops, (...)
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  21.  14
    Human Pheromones and Food Odors: Epigenetic Influences on the Socioaffective Nature of Evolved Behaviors.James V. Kohl - 2012 - Socioaffective Neuroscience and Psychology 2.
    Background: Olfactory cues directly link the environment to gene expression. Two types of olfactory cues, food odors and social odors, alter genetically predisposed hormone-mediated activity in the mammalian brain. Methods: The honeybee is a model organism for understanding the epigenetic link from food odors and social odors to neural networks of the mammalian brain, which ultimately determine human behavior. Results: Pertinent aspects that extend the honeybee model to human behavior include bottom-up followed by top-down gene, cell, tissue, organ, organ-system, (...)
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  22. Mark Rothko and Romy Castro.Paulo Alexandre E. Castro (ed.) - 2014 - New York: Thephilosophersbookcompany & Createspace.
    This book is about what Mark Rothko and Romy Castro think about painting. The bottom line placed here is: what is matter for a painter? What they want to communicate with their art? And how they do it? This book seeks to uncover some of the secrets that are in minds painters. In the backgrond, waht unites, apparently, two such different artists is the way they establish intimacy with matter, even that a concept of matter or intimacy may assume (...)
     
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  23.  22
    Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life.Eva Jablonka, Marion J. Lamb & Anna Zeligowski - 2006 - Bradford.
    Ideas about heredity and evolution are undergoing a revolutionary change. New findings in molecular biology challenge the gene-centered version of Darwinian theory according to which adaptation occurs only through natural selection of chance DNA variations. In Evolution in Four Dimensions, Eva Jablonka and Marion Lamb argue that there is more to heredity than genes. They trace four "dimensions" in evolution -- four inheritance systems that play a role in evolution: genetic, epigenetic, behavioral, and symbolic. These systems, they argue, can (...)
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  24. Extended Cognition and the Mark of the Cognitive.Mark Rowlands - 2009 - Philosophical Psychology 22 (1):1 – 19.
    According to the thesis of the extended mind (EM) , at least some token cognitive processes extend into the cognizing subject's environment in the sense that they are (partly) composed of manipulative, exploitative, and transformative operations performed by that subject on suitable environmental structures. EM has attracted four ostensibly distinct types of objection. This paper has two goals. First, it argues that these objections all reduce to one basic sort: all the objections can be resolved by the provision of an (...)
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  25. Mathematics: Truth and Fiction? Review of Mark Balaguer's Platonism and Anti-Platonism in Mathematics.Mark Colyvan & Edward N. Zalta - 1999 - Philosophia Mathematica 7 (3):336-349.
    Mark Balaguer’s project in this book is extremely ambitious; he sets out to defend both platonism and fictionalism about mathematical entities. Moreover, Balaguer argues that at the end of the day, platonism and fictionalism are on an equal footing. Not content to leave the matter there, however, he advances the anti-metaphysical conclusion that there is no fact of the matter about the existence of mathematical objects.1 Despite the ambitious nature of this project, for the most part Balaguer does not (...)
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  26.  20
    An Embodied Model for Sensorimotor Grounding and Grounding Transfer: Experiments With Epigenetic Robots.Angelo Cangelosi & Thomas Riga - 2006 - Cognitive Science 30 (4):673-689.
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  27. Enactivism and Cognitive Science: Triple Review of J. Stewart, O. Gapenne, and E. A. Di Paolo (Eds.), Enaction: Towards a New Paradigm for Cognitive Science; Anthony Chemero, Radical Embodied Cognitive Science; and Mark Rowlands, The New Science of the Mind”. [REVIEW]Robert D. Rupert - 2016 - Mind 125 (497):209-228.
  28.  16
    Blurring the Germline: Genome Editing and Transgenerational Epigenetic Inheritance.Tim Lewens - 2020 - Bioethics 34 (1):7-15.
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  29. The Philosophical Work of Mark Sharlow: An Introduction and Guide.Mark F. Sharlow - manuscript
    Provides an overview of Mark Sharlow's philosophical work with summaries of his positions. Includes references and links to his writings.
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  30.  13
    On the Genetic and Epigenetic Bases of Primate Signal Processing.Louis J. Goldberg & Leonard A. Rosenblum - 2013 - Biosemiotics 6 (2):161-176.
    Four sequential, sub-processes are identified as the fundamental steps in the processing of signals by big-brained animals. These are, Detection of the signal, its Representation in correlated sensory brain structure, the Interpretation of the signal in another part of the brain and the Expression of the receiver’s response. We label this four-step spatiotemporal process DRIE. We support the view that when the context within which such signals are produced and received is relatively constant, the DRIE process can be ultimately assimilated (...)
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  31. The Unfinishable Scroll and Beyond: Mark Sharlow's Blogs, July 2008 to March 2011.Mark F. Sharlow - manuscript
    An archive of Mark Sharlow's two blogs, "The Unfinishable Scroll" and "Religion: the Next Version." Covers Sharlow's views on metaphysics, epistemology, mind, science, religion, and politics. Includes topics and ideas not found in his papers.
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  32. Review of Mark Schroeder, Slaves of the Passions[REVIEW]David Sobel - 2009 - Notre Dame Philosophical Reviews 2009 (4).
    I assess Schroeder's book Slaves of the Passions and isolate some grounds for concerns about the overall position.
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  33.  87
    The Making of British Socialism by Mark Bevir, And: Karl Marx: A Nineteenth-Century Lifeby Jonathan Sperber (Review).Mark Allison - 2014 - Utopian Studies 25 (1):221-226.
    In the twenty-four years since the dismantling of the Berlin Wall, a body of high-quality scholarship on socialism has slowly accumulated. Here I discuss two superb additions to this incipient post–Cold War canon, Mark Bevir’s The Making of British Socialism and Jonathan Sperber’s Karl Marx: A Nineteenth Century Life. Both authors take it as axiomatic that the socialist utopia, with its quasi-eschatological promise of complete human emancipation, is an idea whose time has passed. But Bevir and, to a lesser (...)
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  34.  64
    Mark T. Conard, Ed. (2009) The Philosophy of the Coen Brothers.Taylor Benjamin Worley - 2011 - Film-Philosophy 15 (1):240-246.
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  35.  48
    Perceptual Displacement of a Test Mark Toward the Larger of Two Visual Objects.Coleman T. Merryman & Frank Restle - 1970 - Journal of Experimental Psychology 84 (2):311.
  36.  11
    From Oblivion to Memory: A Blueprint for the Amnesty: Mark Freeman: Necessary Evils: Amnesties and the Search for Justice, Cambridge University Press, New York, 2009, 352 Pp, ISBN 978-0-521-89525-5. [REVIEW]Mark A. Drumbl - 2012 - Criminal Law and Philosophy 6 (3):467-477.
    This Review Essay examines Mark Freeman’s thoughtful book, Necessary Evils: Amnesties and the Search for Justice. One of the book’s core arguments is that amnesties from criminal prosecution, however unpalatable to liberal legalist sensibilities, should not be entirely purged from the toolbox of post-conflict transitions. Although advancing this argument, Freeman also struggles with it, and ultimately builds a very restrained and heavily technocratic defense of the amnesty. This Review Essay weighs this argument, among others, on its own terms and (...)
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  37. Mark Twain and the Limits of Power Emerson's God in Ruins.James L. Johnson - 1982
     
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  38. Intentionality as the Mark of the Mental.Tim Crane - 1998 - In Royal Institute of Philosophy Supplement. Cambridge University Press. pp. 229-251.
    ‘It is of the very nature of consciousness to be intentional’ said Jean-Paul Sartre, ‘and a consciousness that ceases to be a consciousness of something would ipso facto cease to exist’.1 Sartre here endorses the central doctrine of Husserl’s phenomenology, itself inspired by a famous idea of Brentano’s: that intentionality, the mind’s ‘direction upon its objects’, is what is distinctive of mental phenomena. Brentano’s originality does not lie in pointing out the existence of intentionality, or in inventing the terminology, which (...)
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  39. Epigenetic Inheritance and Evolution: The Lamarckian Dimension.Eva Jablonka & Marion Lamb - 2000 - Oxford University Press UK.
    '...a challenging and useful book, both because it provokes a careful scrutiny of one's own basic ideas regarding evolutionary theory, and because it cuts across so many biological disciplines.' -The Quarterly Review of Biology 'In my view, this work exemplifies Theoretical Biology at its best...here is rampant speculation that is consistently based on cautious reasoning from the available data. Even more refreshing is the absence of sloganeering, grandstanding, and 'isms'.' -Biology and Philosophy 'Epigenetics is fundamental to understanding both development and (...)
     
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  40. Morality and Art: The Case of Huck Finn (Mark Twain's The'Adventures of Huckleberry Finn').Donovan Miyasaki - 2007 - Philosophy and Literature 31 (1):125-132.
    In the following essay, I argue that in the case of some works of art, moral evaluation should not play a role in artistic appraisal. While I reject the strong ethicist’s view—the view that moral evaluation may inform the artistic evaluation of any artwork—I will not do so in favor of the aestheticist’s position. The aestheticist argues for a rigid distinction between the moral and aesthetic evaluation of an artwork. On this view, the moral status of the work is independent (...)
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  41. The Mark of the Cognitive.Fred Adams & Rebecca Garrison - 2013 - Minds and Machines 23 (3):339-352.
    It is easy to give a list of cognitive processes. They are things like learning, memory, concept formation, reasoning, maybe emotion, and so on. It is not easy to say, of these things that are called cognitive, what makes them so? Knowing the answer is one very important reason to be interested in the mark of the cognitive. In this paper, consider some answers that we think do not work and then offer one of our own which ties cognition (...)
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  42. Review of A Mark of the Mental. [REVIEW]Angela Mendelovici & David Bourget - 2019 - Philosophical Review 128 (3):378-385.
    Karen Neander's A Mark of the Mental is a noteworthy and novel contribution to the long-running project of naturalizing intentionality. The aim of the book is to “solve the part of Brentano’s problem that is within reach” (3). Brentano's problem is the problem of explaining intentionality; the part of this problem that is supposedly within reach is that of explaining nonconceptual sensory-perceptual intentionality; and Neander aims to solve it via an informational teleosemantic theory. In this review, we provide a (...)
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  43. Brentano's Concept of Mind: Underlying Nature, Reference-Fixing, and the Mark of the Mental.Uriah Kriegel - 2017 - In Sandra Lapointe & Christopher Pincock (eds.), Innovations in the History of Analytical Philosophy. London: Palgrave-Macmillan. pp. 197-228.
    Perhaps the philosophical thesis most commonly associated with Brentano is that intentionality is the mark of the mental. But in fact Brentano often and centrally uses also what he calls ‘inner perception’ to demarcate the mental. In this paper, I offer a new interpretation of Brentano’s conception of the interrelations between mentality, intentionality, and inner perception. According to this interpretation, Brentano took the concept of mind to be a natural-kind concept, with intentionality constituting the underlying nature of the mental (...)
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  44. Review of Mark Timmons (Ed.), Oxford Studies in Normative Ethics, Vol. 1[REVIEW]Noell Birondo - 2014 - Journal of Moral Philosophy 11 (5):669-672.
    This volume initiates a welcome new Oxford Studies series based on the annual meeting of the Arizona Workshop in Normative Ethics, organized by Mark Timmons. The back matter indicates that the series is a place where, "Leading philosophers present original contributions to our understanding of a wide range of moral issues and positions." But Timmons himself says more accurately, it seems, that the series aims to provide "some of the best contemporary work in the field of contemporary ethical theory" (...)
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  45. Mark Schroeder’s Hypotheticalism: Agent-Neutrality, Moral Epistemology, and Methodology. [REVIEW]Tristram McPherson - 2012 - Philosophical Studies 157 (3):445-453.
    Symposium contribution on Mark Schroeder's Slaves of the Passions. Argues that Schroeder's account of agent-neutral reasons cannot be made to work, that the limited scope of his distinctive proposal in the epistemology of reasons undermines its plausibility, and that Schroeder faces an uncomfortable tension between the initial motivation for his view and the details of the view he develops.
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  46.  71
    Epigenetic Responsibility.Maria Hedlund - 2012 - Medicine Studies 3 (3):171-183.
    The purpose of this article is to argue for a position holding that epigenetic responsibility primarily should be a political and not an individual responsibility. Epigenetic is a rapidly growing research field studying regulations of gene expression that do not change the DNA sequence. Knowledge about these mechanisms is still uncertain in many respects, but main presumptions are that they are triggered by environmental factors and life style and, to a certain extent, heritable to subsequent generations, thereby reminding (...)
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  47.  58
    The Mirage of Mark-to-Market: Distributive Justice and Alternatives to Capital Taxation.Charles Delmotte & Nick Cowen - forthcoming - Critical Review of International Social and Political Philosophy:1-24.
    Substantially increased wealth inequality across the developed world has prompted many philosophers, economists and legal theorists to support comprehensive taxes on all forms of wealth. Proposals include levying taxes on the basis of total wealth, or alternatively the change in the value of capital holdings measured from year-to-year. This contrasts with most existing policies that tax capital assets at the point they are transferred from one beneficiary to another through sale or gifts. Are these tax reforms likely to meet their (...)
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  48. Do Possible Worlds Compromise God's Beauty? A Reply to Mark Ian Thomas Robson.Jon Robson - 2012 - Religious Studies 48 (4):515 - 532.
    In a recent article Mark Ian Thomas Robson argues that there is a clear contradiction between the view that possible worlds are a part of God's nature and the theologically pivotal, but philosophically neglected, claim that God is perfectly beautiful. In this article I show that Robson's argument depends on several key assumptions that he fails to justify and as such that there is reason to doubt the soundness of his argument. I also demonstrate that if Robson's argument were (...)
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  49. Cognitive Extension: The Parity Argument, Functionalism, and the Mark of the Cognitive.Sven Walter - 2010 - Synthese 177 (2):285-300.
    During the past decade, the so-called “hypothesis of cognitive extension,” according to which the material vehicles of some cognitive processes are spatially distributed over the brain and the extracranial parts of the body and the world, has received lots of attention, both favourable and unfavourable. The debate has largely focussed on three related issues: (1) the role of parity considerations, (2) the role of functionalism, and (3) the importance of a mark of the cognitive. This paper critically assesses these (...)
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  50. Genetic, Epigenetic and Exogenetic Information.Karola Stotz & Paul Edmund Griffiths - 2017 - In Richard Joyce (ed.), The Routledge Handbook of Evolution and Philosophy. London & New York: Routledge.
    We describe an approach to measuring biological information where ‘information’ is understood in the sense found in Francis Crick’s foundational contributions to molecular biology. Genes contain information in this sense, but so do epigenetic factors, as many biologists have recognized. The term ‘epigenetic’ is ambiguous, and we introduce a distinction between epigenetic and exogenetic inheritance to clarify one aspect of this ambiguity. These three heredity systems play complementary roles in supplying information for development. -/- We then consider (...)
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